164,950 results match your criteria retrospective case

Refractive and keratometric outcomes of supervised novice surgeon-performed limbal relaxing incisions: 1-year results.

J Cataract Refract Surg 2021 Oct;47(10):1319-1326

From the Dean McGee Eye Institute, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma (Riaz, Kloek); Cullen Eye Institute, Baylor College of Medicine, Houston, Texas (Wang, Koch); Department of Ophthalmology and Visual Science, University of Chicago, Chicago, Illinois (Williams, Farooq); Department of Biostatistics & Epidemiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma (Dvorak).

Purpose: To report refractive and keratometric astigmatism outcomes of resident-performed limbal relaxing incisions (LRIs) during cataract surgery.

Setting: Tertiary care academic teaching hospital.

Design: Retrospective case series. Read More

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October 2021

Adjustment of intraocular lens tilt during intrascleral fixation assisted by intraoperative OCT.

J Cataract Refract Surg 2021 Oct;47(10):1308-1313

From the Kyorin Eye Center, Kyorin University School of Medicine, Tokyo, Japan.

Purpose: To evaluate the efficacy of using intraoperative optical coherence tomography (iOCT) to adjust the tilting of an intraocular lens (IOL) during implantation with intrascleral fixation.

Setting: Kyorin University Hospital, Tokyo, Japan.

Design: Retrospective, case-control, single-center study. Read More

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October 2021

Systematic Review of Outcome Measures Used in Observational Studies of Adults with Eosinophilic Esophagitis.

Int Arch Allergy Immunol 2021 Sep 20:1-25. Epub 2021 Sep 20.

Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland.

Background: Over the last 20 years, diverse outcome measures have been used to evaluate the effectiveness of therapies for eosinophilic esophagitis (EoE). This systematic review aims to identify the readouts used in observational studies of topical corticosteroids, diet, and dilation in adult EoE patients.

Methods: We searched MEDLINE and Embase for prospective and retrospective studies (cohorts/case series, randomized open-label, and case-control) evaluating the use of diets, dilation, and topical corticosteroids in adults with EoE. Read More

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September 2021

A Machine Learning Model for Evaluating Imported Disease Screening Strategies in Immigrant Populations.

Am J Trop Med Hyg 2021 Sep 20. Epub 2021 Sep 20.

Tropical Medicine Unit, Hospital Universitario Central de Asturias (HUCA), Oviedo, Spain.

Given the high prevalence of imported diseases in immigrant populations, it has postulated the need to establish screening programs that allow their early diagnosis and treatment. We present a mathematical model based on machine learning methodologies to contribute to the design of screening programs in this population. We conducted a retrospective cross-sectional screening program of imported diseases in all immigrant patients who attended the Tropical Medicine Unit between January 2009 and December 2016. Read More

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September 2021

Hypoparathyroidism, neutropenia and nephrotic syndrome in a patient with mitochondrial trifunctional protein deficiency: A case report and review of the literature.

Eur J Med Genet 2021 Sep 17:104344. Epub 2021 Sep 17.

Department of Neurology, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, 400014, China; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, 400014, China; Chongqing Key Laboratory of Pediatrics, Chongqing, 400014, China. Electronic address:

Introduction: Mitochondrial trifunctional protein (TFP) deficiency is an autosomal recessive disorder that causes a clinical spectrum of diseases ranging from severe infantile cardiomyopathy to mild chronic progressive neuromyopathy, however, parathyroid glands, hematologic system and kidney damage are not the common presentations of this disease.

Methods: We describe the clinical, biochemical and molecular features of the TFP deficiency patient at our institution. We also provide an extensive literature review of previous published cases with emphasis on the clinical/biochemical phenotype-genotype correlation of this disorder. Read More

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September 2021

Post-clozapine in a clinical setting: A retrospective case note review in Kumamoto, Japan (2009-2019).

Asian J Psychiatr 2021 Sep 7;65:102845. Epub 2021 Sep 7.

Meisei-Hospital, Okubo, Kumamoto, Japan.

Clozapine is commonly prescribed in dopamine supersensitivity psychosis (DSP) cases in Japan. However, limited knowledge on treatment post-clozapine discontinuation use exists. We investigated antipsychotic medications, patient status, and DSP episodes before, during, and after clozapine treatment using medical records of 30 schizophrenia patients (mean age, 51 years; mean illness duration before clozapine treatment, 24 years; mean clozapine treatment duration, 1. Read More

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September 2021

Adult-onset idiopathic dystonia: a national data-linkage study to determine epidemiological, social deprivation and mortality characteristics.

Eur J Neurol 2021 Sep 20. Epub 2021 Sep 20.

Neuroscience and Mental Health Research Institute, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University School of Medicine, Cardiff, UK.

Background And Objectives: Accurate epidemiological information is essential for the improved understanding of dystonia syndromes, as well as better provisioning of clinical services and providing context for diagnostic decision-making. Here, we determine epidemiological, social deprivation and mortality characteristics of adult-onset idiopathic dystonia in the Welsh population.

Methods: A retrospective population-based cohort study using anonymised electronic healthcare data in Wales was conducted to identify individuals with dystonia between January 1 1994 and December 31 2017. Read More

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September 2021

Expanding the clinical spectrum of anti-IgLON5 disease: A multicenter retrospective study.

Eur J Neurol 2021 Sep 20. Epub 2021 Sep 20.

Department of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: We conducted this study to describe detailed clinical characteristics, ancillary test results and treatment response of a group of Chinese patients with anti-IgLON5 disease.

Methods: We recruited 13 patients with positive IgLON5 antibodies in serum and/or cerebrospinal fluid from nine tertiary referral centers. Patients were enrolled from February 2017 to July 2021. Read More

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September 2021

Dystrophic epidermolysis bullosa pruriginosa: a new case series of a rare phenotype unveils skewed Th2 immunity.

J Eur Acad Dermatol Venereol 2021 Sep 20. Epub 2021 Sep 20.

Department of Dermatology, Hôpital Saint Louis, Assistance Publique des Hôpitaux de Paris (AP-HP), Paris, France.

Importance: Dystrophic epidermolysis bullosa pruriginosa (DEB-Pr) is a rare subtype of hereditary epidermolysis bullosa, with a poorly understood pathogenesis and no satisfactory treatment.

Objective: To assess the clinical and biological features, genetic basis and therapeutic management in order to better characterize this rare genodermatosis.

Design: We have conducted a retrospective study, reviewing the clinical presentation, genetic diagnosis, biological analyses and management of patients with dystrophic epidermolysis bullosa pruriginosa. Read More

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September 2021

Hypoxemia in Young Children Undergoing One-lung Ventilation: A Retrospective Cohort Study.

Anesthesiology 2021 Sep 20. Epub 2021 Sep 20.

Background: One-lung ventilation in children remains a specialized practice with low case numbers even at tertiary centers, preventing an assessment of best practices. The authors hypothesized that certain case factors may be associated with a higher risk of intraprocedural hypoxemia in children undergoing thoracic surgery and one-lung ventilation.

Methods: The Multicenter Perioperative Outcomes database and a local quality improvement database were queried for documentation of one-lung ventilation in children 2 months to 3 yr of age inclusive between 2010 and 2020. Read More

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September 2021

Factors associated with severe sepsis in diarrheal adults and their outcome at an urban hospital, Bangladesh: A retrospective analysis.

PLoS One 2021 20;16(9):e0257596. Epub 2021 Sep 20.

Nutrition and Clinical Services Division (NCSD), International Centre for Diarhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh.

Background: To describe factors associated with severe sepsis in diarrheal adults and their outcomes and offender in blood and stool to understand their interplay as clinical features of sepsis and severe diarrhea often overlap.

Methods And Results: We used this retrospective chart analysis employing an unmatched case-control design to study critically ill diarrheal adults aged ≥18 years treated in ICU of Dhaka hospital, icddr,b between January 2011 to December 2015. Of 8,863 in-patient diarrheal adults, 350 having severe sepsis were cases and an equal number of randomly selected non-septic patients were the controls. Read More

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September 2021

Feline sialocoele: clinical presentation, treatment and outcome in 19 cases.

J Feline Med Surg 2021 Sep 20:1098612X211046197. Epub 2021 Sep 20.

Eastcott Referrals Veterinary Hospital, Swindon, UK.

Objectives: The aim of this retrospective observational study was to describe the clinical presentation, treatment and outcome of cats with sialocoele.

Methods: Clinical records from seven referral hospitals were retrospectively searched to identify cats with sialocoele between 2007 and 2021.

Results: Nineteen cats were identified. Read More

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September 2021

Reactivation of varicella zoster infection presenting as acute retinal necrosis post COVID 19 vaccination in an Asian Indian male.

Eur J Ophthalmol 2021 Sep 18:11206721211046485. Epub 2021 Sep 18.

Department of Cornea and Neurophthalmology, Narayana Nethralaya, Bengaluru, Karnataka, India.

Purpose: To present the clinical features of a rare case of varicella zoster infection following one dose of Coronavirus Disease 2019 (COVID-19) vaccination in an elderly Asian Indian male.

Methods: Retrospective observational case report.

Results: A 71-year-old gentleman presented to us with complaints of reduced vision associated with redness and pain in his right eye for 1 week. Read More

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September 2021

A retrospective study on the prevalence of anti-phospholipid antibodies, thrombotic events and cutaneous signs of vasculopathy in 173 hospitalized COVID-19 patients.

Int J Immunopathol Pharmacol 2021 Jan-Dec;35:20587384211042115

Section of Dermatology, Department of Health Sciences (DISSAL), 9302University of Genoa, Genoa, Italy.

Background: Hypercoagulability is a risk factor of thromboembolic events in COVID-19. Anti-phospholipid (aPL) antibodies have been hypothesized to be involved. Typical COVID-19 dermatological manifestations of livedo reticularis and digital ischemia may resemble cutaneous manifestations of anti-phospholipid syndrome (APS). Read More

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September 2021

The utility of geriatric nutritional risk index to predict outcomes in chronic limb-threatening ischemia.

Catheter Cardiovasc Interv 2021 Sep 19. Epub 2021 Sep 19.

Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

Objectives: To assess geriatric nutritional risk index (GNRI) in patients with chronic limb-threatening ischemia (CLTI).

Background: The prevalence of CLTI continues to rise, with major amputation and mortality remaining prominent. Frailty is a vital risk factor for adverse outcomes in cardiovascular care. Read More

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September 2021

Nasal high flow oxygen therapy in hospitalised neonatal foals.

Equine Vet J 2021 Sep 19. Epub 2021 Sep 19.

Rossdales Equine Hospital, Cotton End Rd, Exning, Newmarket, Suffolk, CB8 7NN, UK.

Background: Respiratory disease is common in critically ill neonatal foals. Traditional oxygen therapy (TOT) with nasal insufflation of oxygen is often used to provide first line respiratory support. Mechanical ventilation is used in foals which require a greater level of support but requires specialist expertise and can be associated with significant complications. Read More

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September 2021

Clinical characteristics of two-hundred thirty-two dogs (2006-2018) treated for suspected anaphylaxis in Perth, Western Australia.

Aust Vet J 2021 Sep 19. Epub 2021 Sep 19.

College of Science, Health, Engineering and Education, Murdoch University, Perth, Western Australia, Australia.

Objective: To describe the clinical features of dogs treated for suspected anaphylaxis in Perth, Western Australia.

Design: Single-centre observational case series with retrospective and prospective phases.

Methods: This was a two-phase study of dogs with clinical suspicion of anaphylaxis presenting to the emergency service of a university teaching hospital. Read More

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September 2021

Potential role of biochemical placentation markers - pregnancy associated plasma protein-A and human chorionic gonadotropin for early gestational diabetes screening - a pilot study.

Ginekol Pol 2021 Sep 20. Epub 2021 Sep 20.

Department of Internal Medicine, Medical University -Sofia, Sofia, Bulgaria;Clinic of Endocrinology, University Hospital, Sofia, Bulgaria.

Objectives: Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications. The universal screening for GDM is usually performed between 24-28 weeks' gestation. This often delays the diagnosis and could increase the risk of adverse pregnancy outcomes. Read More

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September 2021

Breathing dystonia in Meige syndrome.

Clin Park Relat Disord 2021 28;5:100106. Epub 2021 Aug 28.

Ear, Nose & Throat Department, St George's Hospital, London, United Kingdom.

Background: Dyspnoea is rarely mentioned in the clinical description of adult-onset isolated dystonia. In this study, we present the clinical features of 13 patients with Meige syndrome (cranio-cervical dystonia) with breathing difficulties.

Methods: A retrospective case note review was performed of patients presenting with Meige syndrome and shortness of breath, to a neuro-laryngology MDT clinic. Read More

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"Double-Pulley" Dual-Row Technique for Arthroscopic Fixation of Large Bony Bankart Lesion: Minimum 2-Year Follow-up With CT Evaluation.

Orthop J Sports Med 2021 Sep 15;9(9):23259671211029239. Epub 2021 Sep 15.

Sports Medicine Department, Beijing Jishuitan Hospital, Peking University School of Medicine, Beijing, China.

Background: A "double-pulley" dual-row technique had been applied for arthroscopic fixation of large bony Bankart lesion in which the fragment has a wide base.

Purpose: To investigate clinical outcomes and glenoid healing after arthroscopic fixation of bony Bankart lesion using the double-pulley dual-row technique.

Study Design: Case series; Level of evidence, 4. Read More

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September 2021

Simultaneous pars plana vitrectomy, panretinal photocoagulation, cryotherapy, and Ahmed valve implantation for neovascular glaucoma.

Int J Ophthalmol 2021 18;14(9):1396-1401. Epub 2021 Sep 18.

Institut Clínic d'Oftalmologia (ICOF), Hospital Clínic, Barcelona 08028, Spain.

Aim: To describe and evaluate the efficacy of Ahmed glaucoma valve implantation (AGV) combined with pars plana vitrectomy (PPV) in a single surgical act for the treatment of advanced neovascular glaucoma (NVG).

Methods: Retrospective observational case series included 51 eyes from 50 patients with severe NVG treated with PPV, AGV, and panretinal photocoagulation and/or cryotherapy in a single surgical act during a 13-year period (2005-2018). Preoperative, intraoperative and postoperative data at day 1 and months 1, 3, 6, 21, and 24 were systematically collected. Read More

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September 2021

Evaluation of a new nomogram for Ferrara ring segment implantation in keratoconus.

Int J Ophthalmol 2021 18;14(9):1371-1383. Epub 2021 Sep 18.

Department of Optics, Pharmacology, and Anatomy, University of Alicante, Alicante 03690, Spain.

Aim: To evaluate the short-term clinical outcomes of Ferrara rings in keratoconus using an optimized nomogram developed after several years of research and retrospective analysis of clinical data.

Methods: This prospective longitudinal non-comparative clinical trial evaluated 88 eyes of 88 patients (age 18-62y) with keratoconus diagnosis from two Spanish centers. Ferrara ring segment (AJL Ophthalmic) implantation was performed in all cases, using the mechanical procedure in 25 eyes (28. Read More

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September 2021

Impact of COVID-19 on gastroenterology fellowship training: a multicenter analysis of endoscopy volumes.

Endosc Int Open 2021 Oct 16;9(10):E1572-E1578. Epub 2021 Sep 16.

Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States.

The COVID-19 pandemic has had a profound impact on gastroenterology training programs. We aimed to objectively evaluate procedural training volume and impact of COVID-19 on gastroenterology fellowship programs in the United States. This was a retrospective, multicenter study. Read More

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October 2021

Miliary tuberculosis presenting as bilateral pseudo-retinoblastoma.

GMS Ophthalmol Cases 2021 28;11:Doc12. Epub 2021 Jul 28.

Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, Chennai, Tamil Nadu, India.

To describe an interesting case of miliary tuberculosis mimicking retinoblastoma. A retrospective case report. The twin brother of a known case of retinobastoma presented with headache. Read More

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Use of Vancomycin Mixed Bone Graft and Vancomycin Mixed Saline Wash Before Wound Closure Reduces the Rate of Infection in Lumbar Spine Fusion Surgery.

Cureus 2021 Aug 18;13(8):e17275. Epub 2021 Aug 18.

Orthopaedics, All India Institute of Medical Sciences, Raipur, IND.

This study aims to evaluate whether surgical site vancomycin mixed in bone grafts and local vancomycin mixed in normal saline wash before wound closure decrease the infection rates in patients undergoing lumbar spinal instrumentation and posterolateral fusion. A retrospective study was performed on cases between 2017 and 2019, who underwent lumbar spine instrumentation and posterolateral fusion for lumbar canal stenosis or listhesis. The routine prophylactic procedures were performed in all patients as per institutional protocol. Read More

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Morphological Spectrum and Survival Analysis of Diffuse Midline Glioma With H3K27M Mutation.

Cureus 2021 Aug 17;13(8):e17267. Epub 2021 Aug 17.

Histopathology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.

Background Diffuse midline gliomas with the H3K27M mutation are now recognized as separate entities due to their unique molecular signature, clinical features, and adverse outcome. Objective To determine the morphological spectrum and survival rate of diffuse midline gliomas with H3K27M mutation. Material and methods This retrospective study was conducted between January 2015 and January 2021 at Shaukat Khanum Memorial Cancer Hospital and Research Centre. Read More

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Preliminary Evaluation of a New Orthotic for Patellofemoral and Multicompartment Knee Osteoarthritis.

Rehabil Res Pract 2021 6;2021:5923721. Epub 2021 Sep 6.

Spring Loaded Technology, Halifax, Canada.

Purpose: Traditional knee osteoarthritis (OA) braces are usually indicated for a minority of patients with knee OA, as they are only suitable for those with unicompartmental disease affecting the tibiofemoral joint. A new assistive brace design is intended for use in a wider range of knee OA patients with heterogeneous symptoms characteristic of patellofemoral, tibiofemoral, or multicompartmental knee OA. The purpose of this case series was to explore whether the use of this novel "tricompartment offloader" (TCO) brace was associated with clinically relevant improvements in pain and function. Read More

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September 2021

Anthropometrics of Estonian children in relation to family disruption: Thrifty phenotype and Trivers-Willard effects.

Evol Med Public Health 2021 20;9(1):276-286. Epub 2021 Jul 20.

Department of Zoology, University of Tartu, Vanemuise 46, Tartu 51014, Estonia.

Background And Objectives: The thrifty phenotype hypothesis proposes that at resource limitation, the growth of some organs/tissues is selectively spared to preserve more critical ones, such as the brain or lungs. The Trivers-Willard hypothesis (TWH) predicts that boys are more vulnerable in the case of resource limitation than girls. Both hypotheses were tested in children from disrupted families, differing in the extent of deprivation/adversities imposed on them. Read More

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Analysis of risk factor for pediatric intensive care unit delirium in children: a case-control study.

Am J Transl Res 2021 15;13(8):9143-9151. Epub 2021 Aug 15.

School of Nursing, Naval Medical University Shanghai, China.

Objective: This study aimed to survey the prevalence of delirium in the pediatric intensive care unit (PICU) and explore the associated risk factors.

Design: A retrospective case-control study.

Setting: Two PICUs within a tertiary-A general hospital. Read More

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Evaluation of the tolerability and effectiveness of Tenecteplase in patients with ST-Segment-Elevation Myocardial Infarction in a Secondary Hospital in Malaysia: A Retrospective Case Series.

Curr Ther Res Clin Exp 2021 21;95:100641. Epub 2021 Aug 21.

Clinical Research Centre, Hospital Taiping, Ministry of Health Malaysia, Perak, Malaysia.

Background: In Malaysia, knowledge regarding the clinical efficacy of tenecteplase (TNK), a fibrin-specific tissue-plasminogen activator, is limited.

Objectives: To evaluate the effectiveness and tolerability of TNK in patients with ST-segment-elevation myocardial infarction in a secondary referral Malaysian hospital.

Methods: This was a single-center retrospective case series based on the medical records of patients with ST-segment-elevation myocardial infarction admitted to the cardiac care unit between January 2016 and May 2019. Read More

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