73 results match your criteria retraction determinants


Fibrinolysis in Platelet Thrombi.

Int J Mol Sci 2021 May 12;22(10). Epub 2021 May 12.

Faculty of Medicine, National Heart and Lung Institute, Imperial College, London SW3 6LY, UK.

The extent and duration of occlusive thrombus formation following an arterial atherothrombotic plaque disruption may be determined by the effectiveness of endogenous fibrinolysis. The determinants of endogenous fibrinolysis are the subject of much research, and it is now broadly accepted that clot composition as well as the environment in which the thrombus was formed play a significant role. Thrombi with a high platelet content demonstrate significant resistance to fibrinolysis, and this may be attributable to an augmented ability for thrombin generation and the release of fibrinolysis inhibitors, resulting in a fibrin-dense, stable thrombus. Read More

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Retraction: Determinants of self-reported adherence to inhaler therapy in patients with chronic obstructive pulmonary disease.

Multidiscip Respir Med 2020 Jan 23;15(1):721. Epub 2020 Sep 23.

S.C. Pneumologia U, Respiratory Clinic Città della Salute e della Scienza, Turin, Italy.

[This retracts the article DOI: 10.4081/mrm.2020. Read More

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January 2020

Labor, health and vulnerability in the COVID-19 pandemic.

Cad Saude Publica 2020;36(12):e00178320. Epub 2020 Dec 16.

Faculdade de Medicina da Bahia, Universidade Federal da Bahia, Salvador, Brasil.

This essay discusses the repercussions of the COVID-19 pandemic on the relation between labor and health, from the perspective of the workers' risk and vulnerability. The pandemic has represented a humanitarian crisis, since both the disease and the measures to contain it lead to persistent socioeconomic effects. In this context, the labor category has an important role, either because of the feasibility of maintaining the social distancing and living conditions allowed by the employment relationship, or because of the impossibility of adopting protection strategies due to job insecurity. Read More

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December 2020

Necessities, opportunities, and challenges for tympanic membrane perforation scaffolding-based bioengineering.

Biomed Mater 2020 Dec 1. Epub 2020 Dec 1.

SINANO, Suzhou Institute of Nano-Tech and Nano-Bionics, Suzhou, Jiangsu, 215123, CHINA.

Tympanic membrane perforation is a global clinical dilemma. It occurs as a consequence of object penetration, blast trauma, barotrauma, and middle ear diseases. Tympanic membrane perforation may lead to otitis media, retraction pockets, cholesteatoma, and conductive deafness. Read More

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December 2020

Effects of open rhinoplasty on upper lip position in profile and frontal views.

Br J Oral Maxillofac Surg 2021 02 15;59(2):174-178. Epub 2020 Aug 15.

Social Determinants of Health Research Center, Semnan University of Medical Sciences, Semnan, Iran; Epidemiology and Biostatistics Department, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.

Examining the upper lip position is a key indicator of facial beauty. This study aimed to examine the upper lip position following cosmetic rhinoplasty at the frontal and profile views. The medical records of 67 patients who underwent rhinoplasty with no history of any facial skeletal surgery were obtained from archives. Read More

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February 2021

Forward flexed posture: reliability and determinants of tragus-to-wall measurement.

Physiother Theory Pract 2020 May 29:1-8. Epub 2020 May 29.

Physical Therapy, Campbell University College of Pharmacy and Health Sciences, Buies Creek, NC, USA.

Introduction: Forward flexed posture is an impairment in body structure commonly seen among older adults and those with pathologies such as ankylosing spondylitis and osteoporosis. Accurate measurement of forward flexed posture is important as it is related to pain, mobility limitations, and falls. Our purpose was to examine the reliability and determinants of forward flexed posture as indicated by tragus-to-wall (TTW) distance. Read More

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Substrate-rigidity dependent migration of an idealized twitching bacterium.

Soft Matter 2019 Aug 23;15(30):6224-6236. Epub 2019 Jul 23.

Theoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Juelich, D-52425 Juelich, Germany.

Mechanical properties of the extracellular matrix are important determinants of cellular migration in diverse processes, such as immune response, wound healing, and cancer metastasis. Moreover, recent studies indicate that even bacterial surface colonization can depend on the mechanics of the substrate. Here, we focus on physical mechanisms that can give rise to substrate-rigidity dependent migration. Read More

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Visual and Automated CT Measurements of Lung Volume Loss in Idiopathic Pulmonary Fibrosis.

AJR Am J Roentgenol 2019 08 7;213(2):318-324. Epub 2019 May 7.

2 Royal Brompton and Harefield NHS Foundation Trust, London, UK.

The purpose of this study is to establish the relationship between CT markers of lung volume and pulmonary function test (PFT) parameters of lung volume in idiopathic pulmonary fibrosis (IPF). The relationships between PFT-derived parameters of lung volume (forced vital capacity [FVC] and total lung capacity [TLC]) and both CT-derived automated lung volume and manually derived surrogate measurements of lung volume on CT were evaluated in 273 patients (212 men and 61 women; median age, 67 years) with a multidisciplinary diagnosis of IPF. All patients underwent unenhanced volumetric high-resolution CT of the thorax. Read More

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The Use of Mini-Plates for the Treatment of a High-Angle, Dual Bite, Class II Malocclusion.

Turk J Orthod 2019 Mar 8;32(1):52-58. Epub 2019 Jan 8.

Department of Orthodontics, Federal University of Goiás School of Dentistry, Goiânia, Goiás, Brazil.

To present a case report of an orthodontic treatment of a high-angle, dual bite, Class II malocclusion without extractions and with the use of mini-plates. Class II malocclusion treatment protocols vary according to the morphological component of the malocclusion and the magnitude and direction of craniofacial growth. It is generally agreed that the cooperation of the patient and careful planning of anchorage are the key determinants of successful treatment. Read More

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Editorial Commentary: "Doctor, Are You Sure the Steroid Injection Won't Harm My Shoulder?" Perhaps We Should Stop Injecting Corticosteroids and Just Repair Those Rotator Cuffs.

Authors:
Mo Saffarini

Arthroscopy 2019 01;35(1):51-53

Nyon, Switzerland.

Analysis of insurance records indicates that 2 or more corticosteroid injections before rotator cuff repair could triple the odds of revision. The cause-and-effect relationship cannot be ascertained because it remains unclear whether steroids worsen outcomes or are injected in shoulders that are worse to start with. Registry studies cannot adjust for lesional determinants of prognosis and should be interpreted with caution to avoid depriving patients from safe and simple treatments to delay or circumvent surgery. Read More

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January 2019

What Acute Stress Protocols Can Tell Us About PTSD and Stress-Related Neuropsychiatric Disorders.

Front Pharmacol 2018 12;9:758. Epub 2018 Jul 12.

Laboratory of Neuropsychopharmacology and Functional Neurogenomics - Dipartimento di Scienze Farmacologiche e Biomolecolari and Center of Excellence on Neurodegenerative Diseases, University of Milano, Milan, Italy.

Posttraumatic stress disorder (PTSD), the fifth most prevalent mental disorder in the United States, is a chronic, debilitating mental illness with as yet limited options for treatment. Hallmark symptoms of PTSD include intrusive memory of trauma, avoidance of reminders of the event, hyperarousal and hypervigilance, emotional numbing, and anhedonia. PTSD is often triggered by exposure to a single traumatic experience, such as a traffic accident, a natural catastrophe, or an episode of violence. Read More

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Retraction of DNA-bound type IV competence pili initiates DNA uptake during natural transformation in Vibrio cholerae.

Nat Microbiol 2018 07 11;3(7):773-780. Epub 2018 Jun 11.

Department of Biology, Indiana University, Bloomington, IN, USA.

Natural transformation is a broadly conserved mechanism of horizontal gene transfer in bacterial species that can shape evolution and foster the spread of antibiotic resistance determinants, promote antigenic variation and lead to the acquisition of novel virulence factors. Surface appendages called competence pili promote DNA uptake during the first step of natural transformation ; however, their mechanism of action has remained unclear owing to an absence of methods to visualize these structures in live cells. Here, using the model naturally transformable species Vibrio cholerae and a pilus-labelling method, we define the mechanism for type IV competence pilus-mediated DNA uptake during natural transformation. Read More

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Prevalence and severity of ocular involvement in Graves' disease according to sex and age: A clinical study from Babol, Iran.

Caspian J Intern Med 2018 ;9(2):178-183

Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Thyroid-associated eye disease (TED), previously known as Graves' ophthalmopathy is a cosmetically and functionally debilitating disease that is seen worldwide. The aim of this study was to evaluate the prevalence and clinical severity of ocular manifestations of Graves' disease according to sex, age and duration in northern Iran.

Methods: Between April 2011 and March 2012, 105 patients with Graves' disease, underwent ophthalmic examination, including ocular motility, exophthalmometry, intraocular pressure (IOP), slit lamp and fundoscopy. Read More

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January 2018

Rotator Cuff Tear Morphologic Parameters at Magnetic Resonance Imaging: Relationship With Muscle Atrophy and Fatty Infiltration and Patient-Reported Function and Health-Related Quality of Life.

J Comput Assist Tomogr 2018 Sep/Oct;42(5):784-791

Department of Medicine and.

Objective: The aim of this study was to determine the relationship between rotator cuff tear (RCT) morphologic parameters and muscle atrophy and fatty infiltration, and patient-reported outcome measures, in patients with symptomatic full-thickness RCT.

Methods: Rotator cuff tear location, length, width, thickness, and musculotendinous junction position were assessed in 57 magnetic resonance imaging scans and correlated to the outcome measures using multivariate regression analysis.

Results: Supraspinatus tendon tear length (odds ratio [OR], 2. Read More

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September 2018

Retraction Note: Determinants of suboptimal breastfeeding practice in Debre Berhan town, Ethiopia: a cross sectional study.

Int Breastfeed J 2018 7;13:13. Epub 2018 Mar 7.

2Department of Nursing and Midwifery, College of Health Science, Addis Ababa University, Addis Ababa, Ethiopia.

[This retracts the article DOI: 10.1186/s13006-016-0063-z.]. Read More

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RETRACTED ARTICLE: Effective environmental factors on geographical distribution of traffic accidents on pedestrians, downtown of Tehran City.

Int J Inj Contr Saf Promot 2019 12 20;26(4). Epub 2018 Feb 20.

Safety Promotion and Injury Prevention Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

The following article has been retracted from publication in the Taylor & Francis journalAli Moradi, 'Effective environmental factors on geographical distribution of traffic accidents on pedestrians, downtown of Tehran City', , https://doi.org/10.1080/17457300. Read More

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December 2019

Local injection of carrageenan accelerates orthodontic tooth movement: A preliminary experimental animal study.

Int Orthod 2017 12 9;15(4):588-599. Epub 2017 Nov 9.

Social Determinants of Health Research Center, Health research institute, Babol University of Medical Sciences, Babol, Iran.

Background: Orthodontic tooth movement (OTM) can be accelerated by increasing bone turnover. Carrageenan is a common food additive, which can induce inflammation. Hence, it might accelerate OTM. Read More

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December 2017

Defining the Mechanical Determinants of Kingella kingae Adherence to Host Cells.

J Bacteriol 2017 12 31;199(23). Epub 2017 Oct 31.

Cell and Molecular Biology Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA

is an important pathogen in young children and initiates infection by colonizing the posterior pharynx. Adherence to pharyngeal epithelial cells is an important first step in the process of colonization. In the present study, we sought to elucidate the interplay of type IV pili (T4P), a trimeric autotransporter adhesin called Knh, and the polysaccharide capsule in adherence to host cells. Read More

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December 2017

Correlation in histological subtypes with high resolution computed tomography signatures of early stage lung adenocarcinoma.

Transl Lung Cancer Res 2017 Feb;6(1):14-22

Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medical, Nanjing 210002, China;; Nanjing University Institute of Respiratory Medicine, Nanjing 210002, China.

Background: Uncertainty remains on the association between image characteristics of the nodules in computed tomography (CT) scans and lung adenocarcinoma histopathologic subtypes. We aimed to estimate the correlation between preoperative high resolution computed tomography (HRCT) scan and postoperative histopathology of stage IA lung adenocarcinoma in East Asian Chinese population.

Methods: We retrospectively reviewed the clinical records and HRCT images of 190 patients (106 female and 84 male) with resected, preoperatively untreated stage IA adenocarcinomas. Read More

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February 2017

Role of Cyclic Di-GMP and Exopolysaccharide in Type IV Pilus Dynamics.

J Bacteriol 2017 04 28;199(8). Epub 2017 Mar 28.

Department of Physics, University of Cologne, Cologne, Germany

For , levels of cyclic di-GMP (c-di-GMP) govern the transition from the planktonic state to biofilm formation. Type IV pili (T4P) are crucial determinants of biofilm structure and dynamics, but it is unknown how levels of c-di-GMP affect pilus dynamics. Here, we scrutinized how c-di-GMP affects molecular motor properties and adhesive behavior of T4P. Read More

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Labrets in Africa and Amazonia: medical implications and cultural determinants.

Trop Med Int Health 2017 02 12;22(2):232-240. Epub 2016 Dec 12.

Institute for Tropical Medicine, Eberhard-Karls University Tübingen, Tübingen, Germany.

The custom of wearing labrets has a long tradition. Labrets appeared independently several thousand years ago in various culture groups in Asia, Europe, Africa and the Americas. Today, apart from diverse body modifications as increasingly practiced in western civilisations, lip plates and plugs are found among a small number of tribal groups only in Africa and Amazonia. Read More

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February 2017

The growth determinants and transport properties of tunneling nanotube networks between B lymphocytes.

Cell Mol Life Sci 2016 12 28;73(23):4531-4545. Epub 2016 Apr 28.

Department of Immunology, Eötvös Loránd University, Budapest, Hungary.

Tunneling nanotubes (TNTs) are long intercellular connecting structures providing a special transport route between two neighboring cells. To date TNTs have been reported in different cell types including immune cells such as T-, NK, dendritic cells, or macrophages. Here we report that mature, but not immature, B cells spontaneously form extensive TNT networks under conditions resembling the physiological environment. Read More

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December 2016

Epidemiological, clinical and prognostic profile of childhood acute bacterial meningitis in a resource poor setting.

J Neurosci Rural Pract 2015 Oct-Dec;6(4):549-57

Department of Paediatrics, Wesley Guild Hospital, Ilesa, Osun State, Nigeria.

Background: Childhood bacterial meningitis is a neurologic emergency that continues to kill and maims children particularly in developing countries with poor immunization coverage.

Objective: This study set out to assess the hospital incidence, pattern of presentation, etiologic agents, outcome and determinants of mortality among the children admitted with bacterial meningitis at the Wesley Guild Hospital (WGH), Ilesa.

Patients And Methods: We carried out a retrospective review of admitted cases of bacterial meningitis in children aged one month to 15 years at the WGH, Ilesa over a three year period by looking at the hospital records. Read More

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January 2016

Determinants of Return to Play After the Nonoperative Management of Hamstring Injuries in Athletes: A Systematic Review.

Am J Sports Med 2016 Aug 15;44(8):2166-72. Epub 2015 Dec 15.

Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal, Institut de Réadaptation Gingras-Lindsay de Montréal, Montréal, Canada School of Rehabilitation, Université de Montréal, Montréal, Canada

Background: It is important for clinicians to rely on suitable prognosis factors after hamstring injuries because of the high incidence of these injuries and time away from athletic activities.

Purpose: To summarize the current literature on factors that influence return to play after a hamstring injury in athletes.

Study Design: Systematic review. Read More

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Studies on the antiplatelet and antithrombotic profile of anti-inflammatory coumarin derivatives.

J Enzyme Inhib Med Chem 2015 Dec 23;30(6):925-33. Epub 2015 Sep 23.

c Department of Pharmacy , University of Parma , Parma , Italy .

The interest towards coumarin-based structures stems from their polypharmacological profile. Herein, we present a series of Mannich bases and 7-azomethine-linked coumarin derivatives exhibiting antiplatelet and antithrombotic activities, in addition to the already known anti-inflammatory and antioxidant activities. Among others, compounds 15 and 16 were found to be the most potent and selective inhibitors of platelet aggregation whereas compound 3 also proved to be the most potent in the clot retraction assay. Read More

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December 2015

A Vector Force Model of Upper Eyelid Position in the Setting of a Trabeculectomy Bleb.

Ophthalmic Plast Reconstr Surg 2016 Mar-Apr;32(2):127-32

*Department of Ophthalmology and Visual Sciences, Carver College of Medicine and †Department of Biomedical Engineering, University of Iowa, Iowa City, Iowa, U.S.A.; ‡Department of Ophthalmology, Colorado Permanente Medical Group, Denver, Colorado, U.S.A.; §Laser Center, Santo Domingo, Dominican Republic; and ‖Bascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, University of Miami, Miami, Florida, U.S.A.

Purpose: A vector force model for the determination of upper eyelid position in the setting of a trabeculectomy bleb is presented. The model is used to explain the clinical courses of 5 patients with bleb-induced upper eyelid malposition and the efficacy of modalities previously described for the treatment of bleb-induced upper eyelid retraction. The novel use of botulinum toxin in the treatment of bleb-induced eyelid retraction and unique surgical considerations in patients with trabeculectomy blebs undergoing upper eyelid surgery are discussed. Read More

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