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The clinical management of cardiac rehabilitation.

Panminerva Med 2021 May 5. Epub 2021 May 5.

President of the Iberoamerican Society of Prevention and Cardiovascular Rehabilitation, León, Spain.

Cardiac rehabilitation (CR) has pioneered using multidisciplinary teams to attend to all aspects of a patient's illness with high levels of professionalism and quality, provide individualized treatment, and negotiate any changes in lifestyle and treatment course. Clinical management transfers the management capacity and to professionals, thus avoiding any increase in costs and healthcare spending, which can result in quality losses and less social legitimacy. Modern CR has been configured as the most effective comprehensive cardiovascular prevention strategy and must be a part of all cardiovascular health-related processes as a sub-process given its preventive nature. Read More

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Systems biology for crop improvement.

Plant Genome 2021 May 5:e20098. Epub 2021 May 5.

Center of Excellence in Genomics & Systems Biology, International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Patancheru, Hyderabad, 502 324, India.

In recent years, generation of large-scale data from genome, transcriptome, proteome, metabolome, epigenome, and others, has become routine in several plant species. Most of these datasets in different crop species, however, were studied independently and as a result, full insight could not be gained on the molecular basis of complex traits and biological networks. A systems biology approach involving integration of multiple omics data, modeling, and prediction of the cellular functions is required to understand the flow of biological information that underlies complex traits. Read More

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Bmcas-1 plays an important role in response against BmNPV infection in vitro.

Arch Insect Biochem Physiol 2021 May 5:e21793. Epub 2021 May 5.

Jiangsu Key Laboratory of Sericultural Biology and Biotechnology, School of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang, Jiangsu, China.

Apoptosis, as one kind of innate immune system, is involved in host response against pathogens innovation. Caspases play a vital role in the execution stage of host cell apoptosis. It has been reported that Bmcaspase-1 (Bmcas-1) has a close relationship with Bombyx mori nucleopolyhedrovirus (BmNPV) infection for its differentially expressed patterns after viral infection. Read More

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Achieving full-color emission of Cu nanocluster self-assembly nanosheets by the virtue of halogen effects.

Soft Matter 2021 May;17(17):4550-4558

State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, P. R. China. and Green Catalysis Center, College of Chemistry, Zhengzhou University, Zhengzhou, 450001, P. R. China.

Fluorescent Cu nanoclusters (NCs) have shown potential in lighting and display, because Cu is cheap and easily available. Despite recent successes in improving the emission intensity of Cu NCs on the basis of aggregation-induced emission enhancement and self-assembly-induced emission enhancement, the difficulty in tuning the emission color sheds the doubt for achieving high-performance white light-emitting diodes (WLEDs). In this work, halogen effects are utilized to tune the emission color of Cu nanocluster self-assembly nanosheets (NSASs). Read More

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Improved osteogenesis and angiogenesis of theranostic ions doped calcium phosphates (CaPs) by a simple surface treatment process: A state-of-the-art study.

Mater Sci Eng C Mater Biol Appl 2021 May 29;124:112082. Epub 2021 Mar 29.

Department of Materials Engineering, Faculty of Engineering, Ferdowsi University of Mashhad (FUM), Azadi Sq., Mashhad 917794-8564, Iran.

Surface treatment of biomaterials could enable reliable and quick cellular responses and accelerate the healing of the host tissue. Here, a series of calcium phosphates (CaPs) were surface treated by hydrogen peroxide (HO) and the treatment effects were physicochemically and biologically evaluated. For this aim, as-synthesized CaPs doped with strontium (Sr), iron (Fe), silicon (Si), and titanium (Ti) ions were sonicated in HO media. Read More

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Effect of Nitrogen Ion Implantation on the Cavitation Erosion Resistance and Cobalt-Based Solid Solution Phase Transformations of HIPed Stellite 6.

Materials (Basel) 2021 Apr 29;14(9). Epub 2021 Apr 29.

Institute of Physics, Maria Curie-Sklodowska University in Lublin, pl. M. Curie-Sklodowskiej 1, 20-031 Lublin, Poland.

From the wide range of engineering materials traditional Stellite 6 (cobalt alloy) exhibits excellent resistance to cavitation erosion (CE). Nonetheless, the influence of ion implantation of cobalt alloys on the CE behaviour has not been completely clarified by the literature. Thus, this work investigates the effect of nitrogen ion implantation (NII) of HIPed Stellite 6 on the improvement of resistance to CE. Read More

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Charge Carrier Mobility Improvement in Diketopyrrolopyrrole Block-Copolymers by Shear Coating.

Polymers (Basel) 2021 Apr 29;13(9). Epub 2021 Apr 29.

Leibniz-Institut für Polymerforschung Dresden e.V., Hohe Straße 6, 01069 Dresden, Germany.

Shear coating is a promising deposition method for upscaling device fabrication and enabling high throughput, and is furthermore suitable for translating to roll-to-roll processing. Although common polymer semiconductors (PSCs) are solution processible, they are still prone to mechanical failure upon stretching, limiting applications in e.g. Read More

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Investigation of the Effect of Mixing Time on the Mechanical Properties of Alkali-Activated Cement Mixed with Fly Ash and Slag.

Materials (Basel) 2021 Apr 29;14(9). Epub 2021 Apr 29.

Department of Ocean Civil Engineering, Gyeongsang National University, Tongyeong 53064, Korea.

This is an experiment on the effect of mixing time for alkali-activated cement (AAC) using a binder mixed with ground granulated blast furnace slag (slag) and fly ash (FA) in a ratio of 1:1 on the mechanical properties. The mixing method of ASTM C305 was used as the basic mixing method, and the following mixing method was changed. Simply adding the same mixing time and procedure, the difference in the order of mixing slag and FA, and controlling the amount of activator and mixed water were considered. Read More

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Evaluation of TiO Based Photocatalytic Treatment of Odor and Gaseous Emissions from Swine Manure with UV-A and UV-C.

Animals (Basel) 2021 Apr 30;11(5). Epub 2021 Apr 30.

Department of Agricultural and Biosystems Engineering, Iowa State University, Ames, IA 50011, USA.

It is essential to mitigate gaseous emissions that result from poultry and livestock production to increase industry sustainability. Odorous volatile organic compounds (VOCs), ammonia (NH), hydrogen sulfide (HS), and greenhouse gases (GHGs) have detrimental effects on the quality of life in rural communities, the environment, and climate. This study's objective was to evaluate the photocatalytic UV treatment of gaseous emissions of odor, odorous VOCs, NH, and other gases (GHGs, O-sometimes considered as by-products of UV treatment) from stored swine manure on a pilot-scale. Read More

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Estimation of the Closest In-Path Vehicle by Low-Channel LiDAR and Camera Sensor Fusion for Autonomous Vehicles.

Sensors (Basel) 2021 Apr 30;21(9). Epub 2021 Apr 30.

Department of Robotics Engineering, Daegu Gyeongbuk Institute of Science & Technology (DGIST), Daegu 333, Korea.

In autonomous driving, using a variety of sensors to recognize preceding vehicles at middle and long distances is helpful for improving driving performance and developing various functions. However, if only LiDAR or cameras are used in the recognition stage, it is difficult to obtain the necessary data due to the limitations of each sensor. In this paper, we proposed a method of converting the vision-tracked data into bird's eye-view (BEV) coordinates using an equation that projects LiDAR points onto an image and a method of fusion between LiDAR and vision-tracked data. Read More

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Development and Processing of Continuous Flax and Carbon Fiber-Reinforced Thermoplastic Composites by a Modified Material Extrusion Process.

Materials (Basel) 2021 Apr 30;14(9). Epub 2021 Apr 30.

TU Braunschweig, Institute for Engineering Design, 38106 Braunschweig, Germany.

Additive manufacturing, especially material extrusion (MEX), has received a lot of attention recently. The reasons for this are the numerous advantages compared to conventional manufacturing processes, which result in various new possibilities for product development and -design. By applying material layer by layer, parts with complex, load-path optimized geometries can be manufactured at neutral costs. Read More

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Dichoptic Perceptual Training in Children With Amblyopia With or Without Patching History.

Invest Ophthalmol Vis Sci 2021 May;62(6)

School of Psychological and Cognitive Sciences, and Beijing Key Laboratory of Behavior and Mental Health, Peking University, Beijing, China.

Purpose: Dichoptic training is becoming a popular tool in amblyopia treatment. Here we investigated the effects of dichoptic demasking training in children with amblyopia who never received patching treatment (NPT group) or were no longer responsive to patching (PT group).

Methods: Fourteen NPT and thirteen PT amblyopes (6-16. Read More

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An uncommon case of nonconvulsive status epilepticus successfully treated with enteral Brivaracetam.

Acta Biomed 2021 Apr 30;92(S1):e2021156. Epub 2021 Apr 30.

Department of Neuroscience, Stroke Unit San Camillo Hospital, Rome.

Background And Aim Of The Work: We present a case of a woman affected by nonconvulsive status epilepticus (NCSE) caused by cerebral hyperperfusion syndrome (CHS) after carotid endarterectomy (CEA) who was successfully treated with Brivaracetam (BRV) administered via nasogastric tube (NGT).

Case Presentation: An 82-years old woman was referred for increasing blood pressure, severe headache and two focal motor seizures on postoperative day four after right CEA. CT scan showed edema of the right hemisphere with a midline shift of 5 mm. Read More

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A quality improvement programme in radiotherapy using workflow audits.

S Afr Med J 2021 Feb 1;111(2):106-109. Epub 2021 Feb 1.

Head of Clinical Governance, Icon Oncology, South Africa; and Emeritus Professor of Radiation Oncology, Faculty of Health Sciences, University of Cape Town, South Africa.

Background: Evaluation of the quality of healthcare depends on measures of structures, processes and outcomes. Progress in recording data allows for better measures of processes, such as the completeness of clinical data, the performance of professional tasks and the use of checklists.

Objectives: To report the results of a radiotherapy (RT) workflow audit and a subsequent online survey of user experience. Read More

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February 2021

Lung-RADS Version 1.0 versus Lung-RADS Version 1.1: Comparison of Categories Using Nodules from the National Lung Screening Trial.

Radiology 2021 May 4:203704. Epub 2021 May 4.

From the Department of Diagnostic Radiology, University of Maryland, 22 S Greene St, Baltimore, MD 21136 (J.K., R.H., J.J., F.D., V.M., C.W.); Philips Research North America, Cambridge, Mass (S.D.); and Philips Healthcare, Highland Heights, Ohio (E.D.).

Background The American College of Radiology updated Lung Imaging Reporting and Data System (Lung-RADS) version 1.0 to version 1.1 in May 2019, with the two key changes involving perifissural nodules (PFNs) and ground-glass nodules (GGNs) now designated as a negative screening result. Read More

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'There's the end of an auld sang': Farewell to the NHS market.

Authors:
Calum Paton

Int J Health Plann Manage 2021 May 4. Epub 2021 May 4.

Public Policy (Health Policy), Keele University, Staffordshire, UK.

The new White Paper, Integration and Innovation, prefiguring a Health and Social Care Bill for England, means that the NHS structure in England will have come full circle in the last 32 years, since the Thatcher government began in 1989 to implement the reforms announced that year in the White Paper, Working for Patients (incidentally without waiting for parliamentary approval, which came in 1990). This will be denied by some, who will depict the 'new' integration as only being possible as a result of learning during the various phases of reform over the last 30 years. This is a fallacious teleology. Read More

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Adapting Existing Resources for Serious Illness Communication Skills Training for Internal Medicine Residents.

South Med J 2021 May;114(5):283-287

From the Division of General Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, the Division of General Internal Medicine, Section of Palliative Care, University of Texas Southwestern Medical Center, Dallas, the Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, Maryland, and the Division of Hospital Medicine, University of California, San Francisco, Zuckerberg San Francisco General Hospital, San Francisco.

Objectives: Goals of care discussions are a vital component of patient care, but Internal Medicine residents receive limited training in these skills. Existing curricula often require simulated patients or faculty development, limiting implementation in many residency programs. Thus, we developed and implemented a curriculum leveraging existing educational resources with the goal of improving resident attitudes and confidence in conducting goals of care discussions in training settings. Read More

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Midterm Outcome of Subtalar Joint Revision Arthrodesis.

Foot Ankle Int 2021 May 3:1071100721995187. Epub 2021 May 3.

Orthopoint, Vienna, Austria.

Background: The outcomes of revision subtalar arthrodesis have received relatively little focus in research compared with primary subtalar arthrodesis outcomes. This study aimed to assess the midterm clinical and radiologic results of subtalar joint revision arthrodesis and to analyze the risk factors that might influence the outcome of this procedure.

Methods: We performed a retrospective review of 20 patients after subtalar joint revision arthrodesis for malunion, using interposition of iliac crest bone graft. Read More

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On the efficient modeling of generic source directivity in Gaussian beam tracing.

J Acoust Soc Am 2021 Apr;149(4):2743

Department of Mechanical and Aerospace Engineering, Hong Kong University of Science and Technology, Clear Water Bay Road, Hong Kong, China.

For large-distance sound propagation with complex obstacles, the Gaussian beam tracing (GBT) method is often applied. An omnidirectional source model is commonly implemented in GBT, which, however, neglects the influence of generic directivity patterns of practical acoustic problems. There have been efforts to synthesize or reproduce the target directivity pattern over an observation surface by using multiple distributed point sources. Read More

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Significance of vacuolar proton pumps and metal/H antiporters in plant heavy metal tolerance.

Authors:
Habib Khoudi

Physiol Plant 2021 May 2. Epub 2021 May 2.

Laboratory of Plant Biotechnology and Improvement, Center of Biotechnology of Sfax (CBS), University of Sfax, Sfax, Tunisia.

Soil and water are among the most valuable resources on earth. Unfortunately, their contamination with heavy metals has become a global problem. Heavy metals are not biodegradable and cannot be chemically degraded; therefore, they tend to accumulate in soils or to be transported by streaming water and contaminate both surface and groundwater. Read More

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Appropriateness and Pattern of Antibiotic Prescription in Pediatric Patients at Adigart General Hospital, Tigray, Ethiopia.

Biomed Res Int 2021 10;2021:6640892. Epub 2021 Apr 10.

Adigrat University, Department of Pharmacy, Adigrat, Ethiopia.

Background: Inappropriate and unnecessary use of antibiotics can increase morbidity, mortality, medical expenses or patient cost, and microbial antibiotic resistance. However, in developing countries like Ethiopia, information regarding appropriateness of antibiotic prescribing pattern to guide improvement strategies is scant.

Objective: The aim of this study was to assess appropriateness and pattern of antibiotic prescription in pediatric patients at pediatric ward of Adigrat General Hospital. Read More

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Improved rheological properties and shelf-life of wheat starch-lipid complex produced by the homogenization process.

Food Sci Biotechnol 2021 Apr 13;30(4):541-544. Epub 2021 Mar 13.

Department of Functional Food and Biotechnology, Jeonju University, Jeonju, 55069 Republic of Korea.

Physical homogenization was applied to the production of a starch-lipid complex formed through a hydrophobic interaction between amylose and fatty acid molecules. In addition, vegetable oils as a source of fatty acids and wheat starch as a source of amylose molecules were used to produce the starch-lipid complex. The complex index was significantly ( < 0. Read More

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The Prevalence of Malaria among Children in Ethiopia: A Systematic Review and Meta-Analysis.

J Parasitol Res 2021 13;2021:6697294. Epub 2021 Apr 13.

Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia.

Background: Malaria is one of the most public health important and life-threatening parasitic infections caused by the protozoan parasite. Since children are immunologically naive to the malaria parasite, they are the main vulnerable groups. During malaria infection, they might have a complication of anemia, cerebral malaria, coma, respiratory distress, and a decrease in cognitive and behavioral improvement. Read More

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Various Neurological Symptoms with Vitamin B12 Deficiency and Posttreatment Evaluation.

J Pediatr Neurosci 2020 Oct-Dec;15(4):365-369. Epub 2021 Jan 19.

Department of Pediatric Neurology, Izmir Katip Celebi University, Izmir, Turkey.

Background: Vitamin B12 deficiency occurs primarily as a result of insufficient dietary intake in children in developing countries. Vitamin B12 deficiency produces a cluster of neurological symptoms in children.

Aim: The aim of this study was to describe the vitamin B12 status of patients who were admitted with neurological symptoms and to evaluate the clinical response to vitamin B12 treatment. Read More

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January 2021

A Major and Stable Quantitative Trait Locus for Seed Size and Shape Traits in a Soybean RIL Population.

Front Genet 2021 16;12:646102. Epub 2021 Apr 16.

Biological Resources and Post-Harvest Division, Japan International Research Center for Agricultural Sciences, Tsukuba, Japan.

Seed size and shape traits are important determinants of seed yield and appearance quality in soybean [ (L.) Merr.]. Read More

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Adaptive Esports for People With Spinal Cord Injury: New Frontiers for Inclusion in Mainstream Sports Performance.

Front Psychol 2021 15;12:612350. Epub 2021 Apr 15.

Department of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

People with Spinal Cord Injury (SCI) are at risk of feeling socially disconnected. Competitive esports present an opportunity for people with SCI to remotely engage in a community. The aim of this study is to discuss barriers to esports participation for people with SCI, present adaptive solutions to these problems, and analyze self-reported changes in social connection. Read More

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Efficacy of Antiangiogenic Drugs in the Treatment of Diabetic Macular Edema: A Bayesian Network Analysis.

Front Pharmacol 2021 15;12:637667. Epub 2021 Apr 15.

Beijing University of Chinese Medicine, Beijing, China.

To compare the efficacy of five kinds of antiangiogenic drugs in the treatment of diabetic macular edema A comprehensive search of seven databases without language restrictions includes PubMed, EMBASE, Web of Science, CBM, the Cochrane Library, CNKI, and WanFang date. All literature used was published before October 2020. Eligible randomized trials were screened for inclusion in this study, and Bayesian framework was used to perform a network meta-analysis (NMA). Read More

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Reduced Functional Connectivity in Children With Congenital Cataracts Using Resting-State Electroencephalography Measurement.

Front Neurosci 2021 14;15:657865. Epub 2021 Apr 14.

Department of Otolaryngology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, China.

Objectives: Numerous task-based functional magnetic resonance imaging studies indicate the presence of compensatory functional improvement in patients with congenital cataracts. However, there is neuroimaging evidence that shows decreased sensory perception or cognition information processing related to visual dysfunction, which favors a general loss hypothesis. This study explored the functional connectivity between visual and other networks in children with congenital cataracts using resting state electroencephalography. Read More

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Quantitative Gait Analysis Using a Pose-Estimation Algorithm with a Single 2D-Video of Parkinson's Disease Patients.

J Parkinsons Dis 2021 Apr 30. Epub 2021 Apr 30.

Department of Neurology, Seoul National University Hospital, Seoul National University, Seoul, South Korea.

Background: Clinician-based rating scales or questionnaires for gait in Parkinson's disease (PD) are subjective and sensor-based analysis is limited in accessibility.

Objective: To develop an easily accessible and objective tool to evaluate gait in PD patients, we analyzed gait from a single 2-dimensional (2D) video.

Methods: We prospectively recorded 2D videos of PD patients (n = 16) and healthy controls (n = 15) performing the timed up and go test (TUG). Read More

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Structural resolution of disaccharides through halogen anion complexation using negative trapped ion mobility spectrometry.

Talanta 2021 Aug 30;230:122348. Epub 2021 Mar 30.

Zhejiang Provincial Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis, Institute of Mass Spectrometry, Ningbo University, Ningbo, 315211, PR China; School of Material Science and Chemical Engineering, Ningbo University, Ningbo, 315211, PR China. Electronic address:

Carbohydrates are an indispensable part of early life evolution. The determination of their structures is a key step to analyze their critical roles in biological systems. A variation of composition, glycosidic linkage, and (or) configuration between carbohydrate isomers induces structure diversity and brings challenges for their structural determination. Read More

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