2,323 results match your criteria restoration interventions

Twelve-Week Quadriceps Strength as A Predictor of Quadriceps Strength At Time Of Return To Sport Testing Following Bone-Patellar Tendon-Bone Autograft Anterior Cruciate Ligament Reconstruction.

Int J Sports Phys Ther 2021 Jun 2;16(3):681-688. Epub 2021 Jun 2.

Northwestern University.

Background: Restoration of quadriceps strength following anterior cruciate ligament reconstruction (ACL-R) continues to challenge both patients and clinicians. Failure to adequately restore quadriceps strength has been linked to decreased patients' self-reported outcomes and an increased risk for re-injury. Early identification of quadriceps strength deficits may assist in tailoring early interventions to better address impairments. Read More

View Article and Full-Text PDF

Prioritizing forest management actions to benefit marine habitats in data-poor regions.

Conserv Biol 2021 Jun 11. Epub 2021 Jun 11.

Seascape Solutions LLC, PO box 223839, Princeville, HI, 96722, USA.

Land-use change is considered one of the greatest human threats to marine ecosystems globally. Given limited resources for conservation, we adapted and scaled up a spatially explicit, linked land-sea decision support tool using open access global geospatial datasets and software to inform the prioritization of future forest management interventions that can have the greatest benefit on marine conservation in Vanuatu. We leveraged and compared outputs from two global marine habitat maps to prioritize land areas for forest conservation and restoration that can maximize sediment retention, water quality, and healthy coastal/marine ecosystems. Read More

View Article and Full-Text PDF

Seed encrusting with salicylic acid: A novel approach to improve establishment of grass species in ecological restoration.

PLoS One 2021 9;16(6):e0242035. Epub 2021 Jun 9.

ARC Centre for Mine Site Restoration, School of Molecular and Life Science, Curtin University, Bentley, Western Australia, Australia.

To achieve global ambitions in large scale ecological restoration, there is a need for approaches that improve the efficiency of seed-based interventions, particularly in overcoming the bottleneck in the transition from germination to seedling establishment. In this study, we tested a novel seed-based application of the plant stress modulator compound salicylic acid as a means to reduce seedling losses in the seed-to-seedling phase. Seed coating technology (encrusting) was developed as a precursor for optimising field sowing for three grass species commonly used in restoration programs, Austrostipa scabra, Microlaena stipoides, and Rytidosperma geniculatum. Read More

View Article and Full-Text PDF

The effect of pre-treatment levels of tooth wear and the applied increase in the vertical dimension of occlusion (VDO) on the survival of direct resin composite restorations.

J Dent 2021 Jun 5:103712. Epub 2021 Jun 5.

Department of Dentistry, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.

Objectives: To investigate the effects of the level of pre-treatment tooth wear and increasing the VDO on the performance of direct resin composite restorations for the rehabilitation of pathological tooth wear.

Methods: Full-mouth (pre-treatment) grading was performed on digital greyscale scan records for 34 participants (35.3 ± 8. Read More

View Article and Full-Text PDF

Targeting angiogenesis for fracture nonunion treatment in inflammatory disease.

Bone Res 2021 Jun 7;9(1):29. Epub 2021 Jun 7.

Department of Orthopaedic Surgery, School of Medicine, Washington University, St. Louis, MO, USA.

Atrophic fracture nonunion poses a significant clinical problem with limited therapeutic interventions. In this study, we developed a unique nonunion model with high clinical relevance using serum transfer-induced rheumatoid arthritis (RA). Arthritic mice displayed fracture nonunion with the absence of fracture callus, diminished angiogenesis and fibrotic scar tissue formation leading to the failure of biomechanical properties, representing the major manifestations of atrophic nonunion in the clinic. Read More

View Article and Full-Text PDF

Ultrasound in Traumatic Spinal Cord Injury: A Wide-Open Field.

Neurosurgery 2021 Jun 7. Epub 2021 Jun 7.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Traumatic spinal cord injury (SCI) is a common and devastating condition. In the absence of effective validated therapies, there is an urgent need for novel methods to achieve injury stabilization, regeneration, and functional restoration in SCI patients. Ultrasound is a versatile platform technology that can provide a foundation for viable diagnostic and therapeutic interventions in SCI. Read More

View Article and Full-Text PDF

Impact of COVID-19 Pandemic on Pre-Treatment Delays, Detection, and Clinical Characteristics of Tuberculosis Patients in Ningxia Hui Autonomous Region, China.

Front Public Health 2021 21;9:644536. Epub 2021 May 21.

National Center for TB Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

To contain the pandemic of COVID-19, China has implemented a series of public health interventions that impacted the tuberculosis control substantially, but these impacts may vary greatly depending on the severity of the local COVID-19 epidemic. The impact of COVID-19 on TB control in Ningxia Hui Autonomous Region is little known. Based on the national TB Information Management System (TBIMS), this study accessed the actual impact of COVID-19 on TB by comparing TB notifications, pre-treatment delays, and clinical characteristics of TB cases between 2020 COVID-19 period and 2017-2019 baseline. Read More

View Article and Full-Text PDF

Immune thrombocytopenia associated with Hashimoto thyroiditis in a pediatric patient: A case report.

Medicine (Baltimore) 2021 Jun;100(22):e26140

Department of Emergency/Key Laboratory of Birth Defects and Related Diseases of Women and Children (Ministry of Education), West China Second University Hospital, Sichuan University, Chengdu, China.

Rationale: Immune thrombocytopenia (ITP) is one of the most commonly acquired bleeding diseases in children. Infection and autoimmune disorders are the most common causes of ITP. The pathogenic mechanism of ITP is complex and is not completely understood. Read More

View Article and Full-Text PDF

Obesity-associated deterioration of the hippocampus is partially restored after weight loss.

Brain Behav Immun 2021 Jun 2. Epub 2021 Jun 2.

Department of Physiology, Faculty of Medical Sciences in Katowice, Medical University of Silesia, Katowice 40-752, Poland.

Objective: Obesity is a multidimensional condition that is treatable by the restoration of a lean phenotype; however, some obesity-related outcomes may persist after weight normalization. Among the organs of the human body, the brain possesses a relatively low regenerative capacity and could retain perturbations established as a result of developmental obesity. Calorie restriction (CR) or a restricted ketogenic diet (KD) are successfully used as weight loss approaches, but their impact on obesity-related effects in the brain have not been previously evaluated. Read More

View Article and Full-Text PDF

Autonomic biomarkers of shock in idiopathic systemic capillary leak syndrome.

PLoS One 2021 1;16(6):e0251775. Epub 2021 Jun 1.

Division of Anesthesiology and Intensive Care, ASST Fatebenefratelli Sacco, Luigi Sacco Hospital-Polo Universitario-University of Milan, Milan, Italy.

Objective: The term Idiopathic Systemic Capillary Leak Syndrome (ISCLS) refers to an uncommon condition of severe distributive shock, resulting from an abrupt shift of fluids and proteins from the intravascular to the interstitial compartment. We hypothesise that the autonomic nervous system (ANS) fails in regulating the response to hypovolemia in acute ISCLS and that ANS variables characterise the progression to the recovery.

Design: Prospective cohort study of patients admitted to ICU for severe ISCLS flares. Read More

View Article and Full-Text PDF

Becoming One with Nature: A Nature Intervention for Individuals Living with Cancer Participating in a Ten-Week Group Exercise and Wellness Program.

Int J Exerc Sci 2021 1;14(3):498-518. Epub 2021 Apr 1.

Department of Psychology, Trent University, Peterborough, ON, CANADA.

Positive outcomes for psychological and physiological health have resulted from a nature experience. However, evidence is limited for nature-based interventions and their effect on a cancer population. The purpose of this mixed-methods study was to determine if incorporating the One Nature Challenge (ONC) into a ten-week group exercise program (WE-Can) for individuals living with cancer could offer additional psychological and/or physiological benefits to those previously observed in WE-Can. Read More

View Article and Full-Text PDF

Exploring autonomic regulation in children with ADHD with and without comorbid anxiety disorder through three systematic levels of cardiac vagal control analysis: Rest, reactivity, and recovery.

Psychophysiology 2021 May 28:e13850. Epub 2021 May 28.

The International Institute for the Advanced Studies of Psychotherapy and Applied Mental Health, Babeʂ-Bolyai University, Cluj-Napoca, Romania.

Autonomic nervous system (ANS) dysregulation, characterized by reduced vagally mediated Heart Rate Variability (HRV), has been associated with Attention-Deficit/ Hyperactivity Disorder (ADHD). This study investigated the dynamic vagal modulation of cardiac output in response to shifts in environmental demands in children and adolescents with ADHD, with and without a comorbid anxiety disorder. High-frequency HRV (HF-HRV) measures were obtained from 46 children and adolescents ranging from 6 to 17 (M = 9. Read More

View Article and Full-Text PDF

Mitochondrial and metabolic dysfunction in Friedreich ataxia: update on pathophysiological relevance and clinical interventions.

Neuronal Signal 2021 Jun 17;5(2):NS20200093. Epub 2021 May 17.

Division of Neurology, Departments of Neurology and Pediatrics, The Children's Hospital of Philadelphia, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, U.S.A.

Friedreich ataxia (FRDA) is a recessive disorder resulting from relative deficiency of the mitochondrial protein frataxin. Frataxin functions in the process of iron-sulfur (Fe-S) cluster synthesis. In this review, we update some of the processes downstream of frataxin deficiency that may mediate the pathophysiology. Read More

View Article and Full-Text PDF

Swimming Exercise Promotes Post-injury Axon Regeneration and Functional Restoration through AMPK.

eNeuro 2021 May-Jun;8(3). Epub 2021 Jun 16.

Department of Biotechnology National Brain Research Centre, Manesar 122052, India

Restoration of lost function following a nervous system injury is limited in adulthood as the regenerative capacity of nervous system declines with age. Pharmacological approaches have not been very successful in alleviating the consequences of nervous system injury. On the contrary, physical activity and rehabilitation interventions are often beneficial to improve the health conditions in the patients with neuronal injuries. Read More

View Article and Full-Text PDF

Quantifying the influences of natural and human factors on the water footprint of afforestation in desert regions of northern China.

Sci Total Environ 2021 Aug 19;780:146577. Epub 2021 Mar 19.

Key Laboratory of Land Surface Pattern and Simulation, Institute of Geographic Sciences and Natural Resources Research, Chinese Academy of Sciences, Beijing 100101, China.

To mitigate desertification and alleviate soil erosion, a wide range of ecological restoration initiatives have been implemented in arid and semi-arid areas, the water consumption of ecological projects and driving mechanisms received increasing attention to balance economy development and ecology restoration at different scales. In this study, the water footprint (WF) was employed as an indicator of water consumption by afforestation, and trend analysis, texture classification and geographical detector methods were used to identify the afforestation area and assess the influences of natural and human factors on the afforestation WF in the desert regions of northern China. The results revealed four major findings. Read More

View Article and Full-Text PDF

Restoration of dysbiotic human gut microbiome for homeostasis.

Life Sci 2021 Aug 17;278:119622. Epub 2021 May 17.

Symbiosis School of Biological Sciences (SSBS), Symbiosis International (Deemed University), Pune, India. Electronic address:

The human microbiome is a complex and dynamic ecosystem, and the imbalance of its microbial community structure from the normal state is termed dysbiosis. The dysbiotic gut microbiome has been proved to be related to several pathological conditions like Inflammatory Bowel Disease (IBD), Irritable Bowel Syndrome (IBS), Colorectal Cancer (CRC), etc., and several other extra-intestinal conditions like Type 1 & 2 diabetes, obesity, etc. Read More

View Article and Full-Text PDF

Specialized post-inpatient psychotherapy for sustained recovery in anorexia nervosa via videoconference - study protocol of the randomized controlled SUSTAIN trial.

J Eat Disord 2021 May 19;9(1):61. Epub 2021 May 19.

Department of Psychosomatic Medicine und Psychotherapy, Medical University Hospital Tübingen, Eberhard Karls University Tübingen, Osianderstr. 5, 72076, Tübingen, Germany.

Background: A major barrier to long-term recovery from anorexia nervosa (AN) are early and frequent relapses after inpatient treatment. There is an urgent need for enhanced continuity of specialized care involving effective aftercare interventions and relapse prevention strategies in order to improve the long-term outcome for patients with AN.

Methods: SUSTAIN is a multi-center, prospective, randomized-controlled trial investigating the efficacy of a novel post-inpatient aftercare intervention for patients with AN as compared to optimized treatment-as-usual (TAU-O). Read More

View Article and Full-Text PDF

Post-ischemic Myocardial Inflammatory Response: A Complex and Dynamic Process Susceptible to Immunomodulatory Therapies.

Front Cardiovasc Med 2021 28;8:647785. Epub 2021 Apr 28.

Department of Surgery, Leiden University Medical Center, Leiden, Netherlands.

Following acute occlusion of a coronary artery causing myocardial ischemia and implementing first-line treatment involving rapid reperfusion, a dynamic and balanced inflammatory response is initiated to repair and remove damaged cells. Paradoxically, restoration of myocardial blood flow exacerbates cell damage as a result of myocardial ischemia-reperfusion (MI-R) injury, which eventually provokes accelerated apoptosis. In the end, the infarct size still corresponds to the subsequent risk of developing heart failure. Read More

View Article and Full-Text PDF

Change in normative eating self-efficacy is associated with six-month weight restoration following inpatient treatment for anorexia nervosa.

Eat Behav 2021 May 8;42:101518. Epub 2021 May 8.

Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, United States of America.

Anorexia nervosa (AN) is a disorder characterized by rigid and restrictive eating behaviors, resulting in significantly low body weight. While specialized behavioral intensive treatment programs can reliably support individuals with AN to normalize eating and weight control behaviors and achieve weight restoration, prognostic factors predicting relapse following treatment are unclear. We examined whether changes in (i) normative eating self-efficacy, (ii) body image self-efficacy, (iii) drive for thinness, and (iv) body dissatisfaction from inpatient admission to six-month follow-up were associated with weight restoration status at program discharge and at six-month follow-up. Read More

View Article and Full-Text PDF

Incidence of postoperative complications and non- periprosthetic fractures after total hip arthroplasty: A more than 10-year follow-up retrospective cohort study.

Phys Ther Res 2021 13;24(1):77-83. Epub 2020 Nov 13.

Department of Orthopaedic Surgery, Shonan Kamakura Joint Reconstruction Center, Japan.

Objective: Postoperative complications and non-periprosthetic fractures (NPPFs), which was defined as a fracture existing non- periprosthetic implant, after total hip arthroplasty (THA) have a negative effect on the patients' ability to perform activities of daily living. Thus, investigating these incidences of patients after THA will be valuable as it lead to a more strategic physical therapy interventions and advanced research to prevent these problems. The purpose of this study was to investigate the incidence of postoperative complications related to implants and NPPFs in patients after THA, a more than 10-year follow-up. Read More

View Article and Full-Text PDF
November 2020

Clinical Outcomes Following the Early Application of Multimodal Scar Programs for Facial Incisional Wounds.

Aesthetic Plast Surg 2021 May 10. Epub 2021 May 10.

Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Severance Hospital, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Background: Even though scars are major issues for patients who undergo facial lacerations, programs for their prevention and early management are not well established. The purpose of this study was to evaluate the clinical outcomes of prophylactic scar assessments and early scar interventions in patients with lacerations.

Patients And Methods: A total of 116 patients underwent suture line and scar prevention treatment in the emergency room from 2014 to 2015. Read More

View Article and Full-Text PDF

Shedding light on therapeutics in alopecia and their relevance to COVID-19.

Clin Dermatol 2021 Jan-Feb;39(1):76-83. Epub 2020 Dec 16.

National and International Skin Registry Solutions (NISR), Charles Institute of Dermatology, University College Dublin, Dublin, Ireland; Hair Restoration Blackrock, Dublin, Ireland.

As of July 9, 2020, there were more than 12 million confirmed cases of coronavirus disease 2019 (COVID-19) across the globe, with more than 550,000 deaths. Many European countries, including Belgium, the United Kingdom, Italy, and Spain, have had the highest numbers of fatalities per capita. This indicates the potential for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus to overwhelm even the most advanced health care systems despite extreme societal interventions. Read More

View Article and Full-Text PDF

Surgical repair techniques, functional outcome, and return to sports after apophyseal avulsion fractures of the ischial tuberosity in adolescents.

Int Orthop 2021 May 8. Epub 2021 May 8.

Department Orthopeadic and Sports Trauma Surgery, Sportklinik Stuttgart GmbH, Taubenheimstrasse 8, 70372, Stuttgart, Germany.

Purpose: Among juvenile apophyseal avulsion injuries of the pelvis in adolescents, fractures of the ischial tuberosity are rare but sustainably debilitating. Also because informations on surgical repair options are very sparse and so far limited to general reviews, reports of individual cases or heterogeous small case series, practitioners, patients and their parental environment still feel a comprehensible hesitation regarding operative treatment. Therefore we intended to investigate patient related outcome measurements and return to sports rates after different types of surgical intervention in an own case series, so far unprecendented in its size. Read More

View Article and Full-Text PDF

Complex interventions in the failing heart.

Curr Opin Organ Transplant 2021 Jun;26(3):267-272

Division of Cardiovascular Diseases.

Purpose Of Review: Heart failure is a complex clinical syndrome with a substantial disease burden. We aim to review the interventional aspects of management of advanced heart failure, focusing on the role of management of coronary artery disease, valvular heart disease, and mechanical circulatory support.

Recent Findings: The patients with coronary artery disease and heart failure requiring revascularization are at higher risk than the rest of the general population. Read More

View Article and Full-Text PDF

The pathways linking objectively-measured greenspace exposure and mental health: A systematic review of observational studies.

Environ Res 2021 07 30;198:111233. Epub 2021 Apr 30.

Behavioural Medicine Laboratory, School of Exercise Science, Physical and Health Education, University of Victoria, Victoria, Canada.

Background: With an increasing volume of research exploring the pathways linking greenspace exposure to mental health, there is a need to synthesise the strength of evidence on the mediation mechanisms. Synthesising the strength of evidence on the pathways can help us better understand how greenspace exposure affects mental health and guide future green space interventions to improve mental health.

Purpose: The purpose of this study was to synthesise current evidence on the pathways linking objectively-measured greenspace exposure and mental health using a systematic review approach. Read More

View Article and Full-Text PDF

Third time recurrent Boerhaave's syndrome: a case report.

J Med Case Rep 2021 May 2;15(1):223. Epub 2021 May 2.

Department of Clinical Sciences in Surgery, Lund University, Lund, Sweden.

Background: Effort rupture of the esophagus or Boerhaave's syndrome is a rare entity, and prognosis is largely dependent on early diagnosis and treatment. Recurrent effort ruptures are very rare, only reported in a few case reports in English literature. We present a case with a third time effort rupture, and to the best of our knowledge there are no such previous publications. Read More

View Article and Full-Text PDF

N-Acetyl-L-leucine improves functional recovery and attenuates cortical cell death and neuroinflammation after traumatic brain injury in mice.

Sci Rep 2021 Apr 29;11(1):9249. Epub 2021 Apr 29.

Department of Anesthesiology, Shock, Trauma and Anesthesiology Research (STAR) Center, University of Maryland School of Medicine, Baltimore, MD, 21201, USA.

Traumatic brain injury (TBI) is a major cause of mortality and long-term disability around the world. Even mild to moderate TBI can lead to lifelong neurological impairment due to acute and progressive neurodegeneration and neuroinflammation induced by the injury. Thus, the discovery of novel treatments which can be used as early therapeutic interventions following TBI is essential to restrict neuronal cell death and neuroinflammation. Read More

View Article and Full-Text PDF

Factor structure of the BDI-II in Parkinson's disease.

Neuropsychology 2021 Apr 29. Epub 2021 Apr 29.

Center for Neurological Restoration, Neurological Institute, Cleveland Clinic.

Objective: There is substantial heterogeneity in depressive symptomology for individuals with Parkinson's disease (PD). It is unknown whether the Beck Depression Inventory-Second Edition (BDI-II) is capable of identifying such phenotypic variations of depression.

Method: We investigated the factor structure of the BDI-II and its associations with demographic characteristics and other nonmotor symptoms in PD. Read More

View Article and Full-Text PDF

Water and sectoral policies in agriculture-forest frontiers: An expanded interdisciplinary research approach.

Ambio 2021 Apr 21. Epub 2021 Apr 21.

Center for International Forestry Research (CIFOR) Germany gGmbH, Charles-de-Gaulle-Strasse 5, 53113, Bonn, Germany.

Major land use changes such as deforestation and restoration influence water resources in agriculture-forest landscapes. Changes are observed in water flows, groundwater infiltration, water quality and rainfall. Interdisciplinary water-forest research has unravelled biophysical parts of the interplay that influences forest and water resources. Read More

View Article and Full-Text PDF

Conservation agriculture-related practices contribute to maize ( L.) yield and soil improvement in Central Malawi.

Heliyon 2021 Mar 31;7(3):e06636. Epub 2021 Mar 31.

Ministry of Agriculture, Irrigation and Water Development, Nkhotakota District Agriculture Office, P. O. Box 41, Nkhotakota, Malawi.

Conservation agriculture-related practices (CARP) improve soil fertility, maize yield, and profitability. A study was conducted to generate evidence on the benefits of CARP in the long-term (nine years) in Salima District, Central Malawi. The objectives of the study were 1) to compare the maize yields between farmer practice and CARP interventions in the long-term, 2) to compare soil fertility changes between farmer practice and CARP interventions in the long-term, and 3) to verify the intercropping efficiency of maize with groundnut using the land equivalent ratio (LER) and land equivalent coefficient (LEC). Read More

View Article and Full-Text PDF