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Chemosphere 2021 Jan 19;263:128007. Epub 2020 Aug 19.

Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing, China; Academy of Agricultural Sciences, Southwest University, Chongqing, China; State Cultivation Base of Crop Stress Biology for Southern Mountainous Land of Southwest University, Southwest University, Chongqing, China. Electronic address:

Selenium is a trace element necessary for living organisms. It exists mainly in the form of selenite in nature. In plants, selenium can enhance defenses against pests. Read More

Bioorg Med Chem Lett 2020 08 12;30(16):127346. Epub 2020 Jun 12.

College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi Province, PR China; Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, Huzhou University, Huzhou 313000, Zhejiang Province, PR China. Electronic address:

Besides structural modification of natural bioactive products to afford promising agrochemical candidates, investigation of their mechanisms of action against pests is also an important strategy to obtain novel potentially botanical pesticides. N-(p-Ethyl)phenylsulfonylmatrinic acid (2), derived from an natural alkaloid matrine (1), exhibited about 5.9-fold more pronounced acaricidal activity than 1 against the adult females of Tetranychus cinnabarinus Boisduval, and good control efficiency in the greenhouse. Read More

Insect Biochem Mol Biol 2020 08 11;123:103413. Epub 2020 Jun 11.

Key Laboratory of Entomology and Pest Control Engineering, College of Plant Protection, Southwest University, Chongqing, China; Academy of Agricultural Sciences, Southwest University, Chongqing, China; State Cultivation Base of Crop Stress Biology for Southern Mountainous Land of Southwest University, Southwest University, Chongqing, China. Electronic address:

Differential expression of metabolic detoxification enzymes is an important mechanism involved in pesticide/acaricide resistance of mite pests. The competing endogenous RNA hypothesis offers a new opportunity to investigate post-transcriptional regulation of those genes. In this study, 4454 long non-coding RNAs were identified in the carmine spider mite Tetranychus cinnabarinus by transcriptome sequencing. Read More

DNA Res 2020 Apr;27(2)

INRAE, UMR1163, Biodiversity and Biotechnology of Fungi, Aix Marseille University, 13009 Marseille, France.

White-rot (WR) fungi are pivotal decomposers of dead organic matter in forest ecosystems and typically use a large array of hydrolytic and oxidative enzymes to deconstruct lignocellulose. However, the extent of lignin and cellulose degradation may vary between species and wood type. Here, we combined comparative genomics, transcriptomics and secretome proteomics to identify conserved enzymatic signatures at the onset of wood-decaying activity within the Basidiomycota genus Pycnoporus. Read More

J Agric Food Chem 2020 Apr 25;68(14):4131-4143. Epub 2020 Mar 25.

College of Plant Protection, Northwest A&F University, Yangling, Shaanxi Province 712100, China.

To discover natural-product-based pesticides, 7β-oxycarbonylandrographolide derivatives were stereoselectively constructed from a labdane diterpenoid andrographolide. Among them, 2'-()Pr-1',3'-dioxin-7β-oxy(-Cl)benzoylandrographolide (), 2'-()Pr-1',3'-dioxin-7β-oxyacetylandrographolide (), 2'-(Me)Ph-1',3'-dioxin-7β-oxy(-Cl)benzoylandrographolide (), and 2'-(Me)Ph-1',3'-dioxin-7β-oxy(-Cl)benzoylandrographolide () against displayed the most promising growth inhibitory activity; 2'-()Pr-1',3'-dioxin-7β-oxy(-Cl)benzoylandrographolide (: LC = 0.406 mg/mL) and (LC = 0. Read More

Molecules 2019 Feb 3;24(3). Epub 2019 Feb 3.

Department of Applied Chemistry, College of Science, China Agricultural University, Beijing 100193, China.

New 1,3,5-trimethylpyrazole-containing malonamide derivatives based on pyflubumide were designed, synthesized, and characterized using ¹H-NMR, C-NMR, and high-resolution mass spectra (HRMS). The results of preliminary bioassays showed that the target compounds possessed good activities against , , and . Most of the target compounds exhibited moderate to good acaricidal activity against at a concentration of 400 µg/mL, and some showed moderate activity at a concentration of 200 µg/mL; in particular, compounds and exhibited 70. Read More

Bioorg Chem 2019 05 17;86:28-33. Epub 2019 Jan 17.

Research Institute of Pesticidal Design & Synthesis, College of Plant Protection/Chemistry and Pharmacy, Northwest A&F University, Yangling 712100, Shaanxi Province, PR China. Electronic address:

To discover new natural-product-based pesticides, we structurally modified andrographolide, a labdane diterpenoid isolated from Andrographis paniculata, and stereoselectively prepared a series of 12α-(substituted)benzylamino-14-deoxyandrographolide derivatives (I-V). Three-dimensional structures of compounds 3c, 3d, IIIa and IIIb were further determined by single-crystal X-ray diffraction. Compounds IIa (R = n-CH, R = PhCH) exhibited more promising insecticidal activity against Mythimna separata than toosendanin. Read More

PLoS One 2018 5;13(11):e0199269. Epub 2018 Nov 5.

Department of Plant Protection, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, P. R. China.

Objective: Tetranychus cinnabarinus (Boisduval) is an agricultural mite pest threatens crops throughout the world, causing serious economic loses. Exploring the effects of acaricides on predatory mites is crucial for the combination of biological and chemical control of T. cinnabarinus. Read More

Bioorg Chem 2018 12 6;81:88-92. Epub 2018 Aug 6.

Research Institute of Pesticidal Design & Synthesis, College of Crop Protection/Chemistry and Pharmacy, Northwest A&F University, Yangling Shaanxi 712100, China; Beijing Key Laboratory of Agricultural Product Detection and Control for Spoilage Organisms and Pesticides, College of Food Science and Engineering, Beijing University of Agriculture, Beijing 102206, China. Electronic address:

In continuation of our program aimed at the development of natural product-based pesticidal agents, a series of matrinic amide derivatives containing 1,3,4-thiadiazole scaffold were prepared, and their insecticidal and acaricidal activities were evaluated against Mythimna separata and Tetranychus cinnabarinus. Some compounds exhibited potent insecticidal and acaricidal activities. It suggested that R as a nitro group and R as a fluorine atom, were important for the insecticidal activity; R as the electron-donating groups and R as the methyl group, were necessary for the acaricidal activity. Read More

Bioorg Med Chem Lett 2018 06 12;28(10):1753-1757. Epub 2018 Apr 12.

Research Institute of Pesticidal Design & Synthesis, College of Sciences/Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi Province, China; State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjing 300071, China. Electronic address:

In continuation of our program to discover natural product-based pesticidal agents, a series of new quinolinomatrine derivatives were prepared. Especially three-dimensional structures of five compounds were unambiguously determined by single-crystal X-ray diffraction. Among them, 21-chloroquinolinomatrine exhibited good insecticidal and acaricidal activities against two crop-threatening insect pests, Mythimna separata and Tetranychus cinnabarinus. Read More

Bioorg Med Chem Lett 2018 02 19;28(3):360-364. Epub 2017 Dec 19.

Research Institute of Pesticidal Design & Synthesis, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi Province, China; State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjing 300071, China; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry and Pharmacy, Northwest A&F University, Yangling 712100, Shaanxi Province, China. Electronic address:

In continuation of our program aimed at the development of natural product-based pesticidal agents, a series of andrographolide-related esters, such as 3,19-dialkyl(aryl)carbonyloxy andrographolide (3a-g), 3-alkyl(aryl)carbonyloxyandrographolide (4a-g), and 19-alkyl(aryl)carbonyloxyandrographolide (5a-g), were prepared. Their structures were well characterized by H NMR, IR, optical rotation, HRMS and mp. Especially three-dimensional structures of compounds 3a, 4g, and 5g were unambiguously confirmed by single-crystal X-ray diffraction. Read More

Bioorg Med Chem Lett 2017 09 16;27(18):4336-4340. Epub 2017 Aug 16.

Research Institute of Pesticidal Design & Synthesis, College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi Province, China; Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry and Pharmacy, Northwest A&F University, Yangling 712100, Shaanxi Province, China. Electronic address:

To develop natural-product-based pesticidal agents, a series of monosaccharide-related ester derivatives (17a-q and 18a-f), glucose (xylose)-piperic acid/piperic acid-like conjugates, were synthesized. Three-dimensional structures of compounds 17b, 17g, 17h, and 17n were unambiguously determined by single-crystal X-ray diffraction. Especially compounds 18e and 18f exhibited the most potent insecticidal and acaricidal activities against Mythimna separata and Tetranychus cinnabarinus. Read More

Front Physiol 2017 11;8:216. Epub 2017 Apr 11.

Key Laboratory of Entomology and Pest Control Engineering of Chongqing, College of Plant Protection, Southwest UniversityChongqing, China.

Abamectin has been widely used as an insecticide/acaricide for more than 30 years because of its superior bioactivity. Recently, an interesting phenomenon was identified in the carmine spider mite, , an important pest in agriculture. The gamma aminobutyric acid (GABA) contents in a laboratory abamectin resistant strain of (AbR) were significantly increased. Read More

Biomed Res Int 2016;2016:2796260. Epub 2016 Sep 8.

College of Plant Protection, Southwest University, Chongqing 400716, China.

is an important agricultural pest with a broad host range. We previously identified curcumin as a promising acaricidal compound against . However, the acaricidal mechanism of curcumin remains unknown. Read More

Bioorg Med Chem Lett 2016 08 7;26(15):3818-21. Epub 2016 May 7.

College of Chemistry and Chemical Engineering, Nantong University, Nantong 226019, People's Republic of China. Electronic address:

A new library of 1,3,4-thiadiazole-containing pyrazole oximes was designed and synthesized. Their acaricidal and insecticidal activities were evaluated. Bioassay results indicated that some target compounds exhibited good acaricidal and insecticidal properties. Read More

Biomed Res Int 2015 11;2015:794718. Epub 2015 May 11.

College of Biological Science and Engineering, Beijing University of Agriculture, Beijing 102206, China ; Key Laboratory of Urban Agriculture (North), Ministry of Agriculture, Beijing 102206, China.

Tetranychus cinnabarinus (Acari: Tetranychidae) is a worldwide polyphagous agricultural pest that has the title of resistance champion among arthropods. We reported previously the identification of the acaricidal compound β-sitosterol from Mentha piperita and Inula japonica. However, the acaricidal mechanism of β-sitosterol is unclear. Read More

Ying Yong Sheng Tai Xue Bao 2013 Jan;24(1):197-204

College of Plant Protection, Southwest University, Chongqing 400716, China.

By using slide-dip bioassay method under laboratory condition, an investigation was made on the lethal effects of scopoletin, bisdemethoxycurcumin (BDMC), and their combination at an optimal mass ratio (7:6) of scopoletin to BDMC against the adult females of Tetranychus cinnabarinus Boisd. A time-dose mortality model (TDM) was established, which passed the Hosmer-Lemeshow test. The sensitivity of the adult females to the concentration change of the acaricides was in the sequence of scopoletin > optimal mass ratio of scopoletin to BDMC > BDMC. Read More

Chemosphere 2012 Oct 19;89(6):708-16. Epub 2012 Jul 19.

Department of Soil Microbiology and Symbiotic Systems, Estación Experimental del Zaidín, Consejo Superior de Investigaciones Científicas, Prof. Albareda 1 Apdo. 419, E-18008 Granada, Spain.

ADOR is an aqueous extract obtained from the dry olive mill residue (DOR) which contains the majority of its soluble phenolic compounds, which are responsible for its phytotoxic properties. Some studies have shown that ADOR negatively affects seed germination. However, to date, few studies have been carried out on the effect of ADOR on the oxidative stress of the plant. Read More

BMC Biotechnol 2010 Sep 14;10:67. Epub 2010 Sep 14.

Lignocellulose Biotechnology Laboratory, Department of Microbiology, University of Delhi South Campus, Benito Juarez Road, New Delhi, India.

Background: White-rot fungi are primarily the major degraders of lignin, a major obstacle for commercial exploitation of plant byproducts to produce bioethanol and other industrially important products. However, to improve their efficacy for lignin degradation, it has become necessary to genetically modify these organisms using appropriate vectors. Agrobacterium tumefaciens, a soil phytopathogenic bacterium, generally transforms plants by delivering a portion of the resident Ti- plasmid, the T-DNA (transfer DNA). Read More

Insect Mol Biol 2009 Apr;18(2):183-94

Key College of Plant Protection Southwest University, Beibei, Chongqing, China.

Three heat shock protein 70 (Hsp70) cDNAs were isolated from the carmine spider mite, Tetranychus cinnabarinus. They were tentatively named as TCHsp70-1, TCHsp70-2 and TCHsp70-3. Structural analyses showed that all of the three TCHsp70 cDNAs held the full open reading frame (ORF). Read More

Ying Yong Sheng Tai Xue Bao 2006 Jul;17(7):1351-3

College of Biotechnology, Jiangsu University of Science and Technology, Zhenjiang 212018, China.

By using Jackknife technique and Wilcoxon (Gehan) statistic method, the LC35 sublethal effect of chlorpyrifos on the population dynamics of Tetranychus cinnabarinus was studied in laboratory. The results showed that under the conditions of 30 degrees C +/- 1degrees C, (70 +/- 15) % RH and a photoperiod of 16L: 8D, there were no significant differences in the longevity of female adult, F1 hatchability, and sex ratio of T. cinnabarinus between chlorpyrifos treatment and the control, but the total oviposition (42. Read More

Oecologia 2003 May 11;135(3):442-50. Epub 2003 Mar 11.

Department of Entomology, University of California, Davis, CA 95616, USA.

We examined the potential of a leaf roller to indirectly influence a community of arthropods. Two mite species are the key herbivores on papaya leaves in Hawaii: a spider mite, Tetranychus cinnabarinus Boisduval, and an eriophyid mite, Calacarus flagelliseta, which induces upward curling of the leaf margin at the end of the summer when populations reach high densities. A survey and three manipulative field experiments demonstrated that (1) leaf rolls induce a consistent shift in the spatial distribution of spider mites and their predators, the coccinellid Stethorus siphonulus Kapur, the predatory mites Phytoseiulus spp. Read More

J Appl Microbiol 2003 ;94(4):618-24

Unité Mixte de Recherche 1163 INRA/Universités de Provence et de la Méditerranée de Biotechnologie des Champignons Filamenteux, IFR 86 de Biotechnologie Agro-Industrielle de Marseille, France.

Aims: Laccase production by the monokaryotic strain Pycnoporus cinnabarinus ss3 was studied using ethanol as inducer in the culture medium.

Methods And Results: The effect of ethanol was tested at 10, 20, 30, 35 and 45 g l-1 and compared with that of ferulic acid, known until now as the most efficient inducer for laccase expression by P. cinnabarinus ss3. Read More

Gene 1999 Aug;236(1):169-77

Institute of General Microbiology and Microbial Genetics, Friedrich-Schiller University Jena, Neugasse 24, D-07743, Jena, Germany.

The gene lcc3-2 encoding a second laccase of the white-rot fungus Pycnoporus cinnabarinus has been cloned, sequenced, and characterized. The isolated gene consists of 2840bp, with the coding region interrupted by ten introns and flanked by an upstream region in which putative CAAT and TATA boxes were identified. The cDNA of lcc3-2 contains an open reading frame of 1563bp. Read More