424 results match your criteria respiratory polygraphy

Contribution of pulse oximetry in relation to respiratory flow events in a home-based approach aimed at diagnosing obstructive sleep apnea.

Sleep Sci 2021 Jan-Mar;14(1):77-81

Hospital Alemán de Buenos Aires, Sleep - Buenos Aires - Capital Federal - Argentina.

Objective: To compare pulse oximetry with manual analysis against all signals of respiratory polygraphy.

Material And Methods: This retrospective study estimated sensitivity (S), specificity (Sp) and positive/negative likelihood ratio (LR+/-) of the oxygen desaturation index (ODI-test) and apnea-hypopnea index (AHI-reference).

Results: 3854 patients (61. Read More

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Sacubitril-valsartan initiation in chronic heart failure patients impacts sleep apnea: the ENTRESTO-SAS study.

ESC Heart Fail 2021 Jun 8. Epub 2021 Jun 8.

PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, Montpellier, France.

Aims: Optimizing medical cardiac treatment for sleep apnoea (SA) in patients with chronic heart failure and reduced ejection fraction (HFrEF) is an expert Grade C recommendation based on six studies encompassing a total of 67 patients only. Whether sacubitril-valsartan (SV), a cornerstone of HFrEF medical treatment, impacts SA is unknown and requires evaluation.

Methods And Results: The ENTRESTO-SAS trial is a six-centre, prospective, open-label real-life cohort study (NCT02916160). Read More

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Azithromycin for the Treatment of Chronic Cough in Idiopathic Pulmonary Fibrosis: A Randomized Controlled Cross-over Trial.

Ann Am Thorac Soc 2021 May 20. Epub 2021 May 20.

Inselspital, Bern University Hospital, University of Bern, Department of Pulmonary Medicine, Bern, Switzerland;

Rationale: Patients with idiopathic pulmonary fibrosis (IPF) frequently suffer from difficult to treat chronic cough, which substantially affects their quality of life. Azithromycin has been demonstrated to relieve chronic cough in some populations, however this has not been investigated in IPF.

Objectives: To determine the safety and efficacy of azithromycin for the treatment of chronic cough in patients with IPF. Read More

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Obstructive sleep apnoea testing and management in atrial fibrillation patients: a joint survey by the European Heart Rhythm Association (EHRA) and the Association of Cardiovascular Nurses and Allied Professions (ACNAP).

Europace 2021 May 17. Epub 2021 May 17.

Centre for Heart Rhythm Disorders, University of Adelaide and Royal Adelaide Hospital, Adelaide, Australia.

Obstructive sleep apnoea (OSA) is highly prevalent in atrial fibrillation (AF) patients and associated with reduced response to rhythm control strategies. However, there is no practical guidance on testing for OSA in AF patients and for OSA treatment implementation. We sought to evaluate current practices and identify challenges of OSA management in AF. Read More

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Nocturnal non invasive ventilation in normocapnic cystic fibrosis patients: a pilot study.

Acta Biomed 2021 05 12;92(2):e2021164. Epub 2021 May 12.

Pediatric Respiratory Unit, San Marco Hospital, Department of Clinical and Experimental Medicine, University of Catania.

Background And Aim: In patients with cystic fibrosis (CF) non-invasive ventilation (NIV) improves lung mechanics and gas exchange, and decreases the work of breathing. Domiciliary NIV is mainly used in hypercapnic patients with severe disease, because it counteracts the progression of lung functional impairment and it is often used as a useful "bridge" to lung transplantation. However, to date, there are no standardized criteria to indicate the effect of a precocious starting of NIV in patients with functional ventilation inhomogeneity without hypercapnia. Read More

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The role of screening questionnaires in the assessment of risk and severity of obstructive sleep apnea - polysomnography versus polygraphy.

Adv Respir Med 2021 ;89(2):188-196

Department of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, Lodz, Poland.

Obstructive sleep apnea (OSA) is a disease of significant importance, which may lead to numerous severe clinical consequences. The gold standard in the diagnosis of this sleep-related breathing disorder (SRBD) is polysomnography (PSG). However, due to the need for high expertise of staff who perform this procedure, its complexity, and relatively low availability, some simpler substitutes have been developed; among them is polygraphy (PG), which is most widely used. Read More

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January 2021

Clinical characteristics of sleep apnea in middle-old and oldest-old inpatients: symptoms and comorbidities.

Sleep Med 2021 Jun 16;82:179-185. Epub 2021 Apr 16.

Sorbonne Université, CNRS, UMR 8256 Biological Adaptation and Aging, F-75005, Paris, France; Assistance Publique - Hôpitaux de Paris (AP-HP), DHU FAST, Functional Explorations and Sleep Investigation Unit for the Older Patients, Charles Foix Hospital, Pitié-Salpêtrière-Charles Foix Group, F-94200, Ivry-sur-Seine, France; Sorbonne Université, UFR Médecine, F-75013, Paris, France. Electronic address:

Background: Obstructive sleep apnea (OSA) is prevalent in older adults but still underdiagnosed for many reasons, such as underreported symptoms, non-specific ones because of the comorbidities and polypharmacy, or the social belief of sleep problems as normal with aging.

Objectives: To identify salient symptoms and comorbidities associated with OSA, diagnosed by nocturnal respiratory polygraphy in geriatric inpatients.

Method: We conducted a retrospective, cross-sectional study in a sample of 102 geriatric inpatients from a French Geriatric University Hospital. Read More

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Effect of Continuous Positive Airway Pressure on Arrhythmia in Atrial Fibrillation and Sleep Apnea: A Randomized Controlled Trial.

Am J Respir Crit Care Med 2021 May 3. Epub 2021 May 3.

Oslo University Hospital, 155272, Oslo, Norway.

Rationale: Sleep apnea (SA) is highly prevalent in patients with atrial fibrillation (AF), and both conditions are associated with adverse cardiovascular outcomes.

Objectives: To determine the effect of continuous positive airway pressure (CPAP) on AF burden.

Methods: This open-label, parallel-group, randomized, controlled trial included patients with paroxysmal AF and moderate-to-severe SA (apnea-hypopnea index ≥15). Read More

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Sleep-Disordered Breathing and Nocturnal Hypoxemia in Precapillary Pulmonary Hypertension: Prevalence, Pathophysiological Determinants, and Clinical Consequences.

Respiration 2021 Apr 28:1-12. Epub 2021 Apr 28.

Institute of Life Sciences, Scuola Superiore Sant'Anna, Pisa, Italy.

Background And Objective: The clinical relevance and interrelation of sleep-disordered breathing and nocturnal hypoxemia in patients with precapillary pulmonary hypertension (PH) is not fully understood.

Methods: Seventy-one patients with PH (age 63 ± 15 years, 41% male) and 35 matched controls were enrolled. Patients with PH underwent clinical examination with assessment of sleep quality, daytime sleepiness, 6-minute walk distance (6MWD), overnight cardiorespiratory polygraphy, lung function, hypercapnic ventilatory response (HCVR; by rebreathing technique), amino-terminal pro-brain natriuretic peptide (NT-proBNP) levels, and cardiac MRI (n = 34). Read More

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Galectin-3 and neutrophil-to-lymphocyte ratio are indicative of heart remodelling and disease severity in patients with obstructive sleep apnoea.

Sleep Med 2021 Jun 9;82:117-124. Epub 2021 Apr 9.

Unit of Internal Medicine "Guido Baccelli", Department of Biomedical Sciences and Human Oncology, University of Bari Aldo Moro Medical School, Piazza Giulio Cesare 11, I-70124 Bari, BA, Italy.

Background: Galectin-3, considered as a new inflammatory marker; it is increased in cardiovascular disease. We investigated Galectin-3 in relation to heart damage in patients with OSA and its role in inflammation, based on the Neutrophil-to-Lymphocyte Ratio (NLR).

Methods: Sixty-three consecutive patients (45 males, 18 females, 58. Read More

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Sleep-disordered breathing and its management in children with rare skeletal dysplasias.

Am J Med Genet A 2021 Apr 28. Epub 2021 Apr 28.

AP-HP, Hôpital Necker-Enfants Malades, Pediatric Noninvasive Ventilation and Sleep Unit, Paris, France.

Sleep-disordered breathing (SDB) is common in patients with skeletal dysplasias. The aim of our study was to analyze SDB and respiratory management in children with rare skeletal dysplasias. We performed a retrospective analysis of patients with spondyloepiphyseal dysplasia congenita (SEDC), metatropic dysplasia (MD), spondyloepimetaphyseal dysplasia (SEMD), acrodysostosis (ADO), geleophysic dysplasia (GD), acromicric dysplasia (AD), and spondylocostal dysplasia (SCD) between April 2014 and October 2020. Read More

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Dysphagia symptoms in obstructive sleep apnea: prevalence and clinical correlates.

Respir Res 2021 Apr 21;22(1):117. Epub 2021 Apr 21.

Division of Respiratory Diseases, Ospedale L. Sacco, ASST-Fatebenefratelli-Sacco, Department of Biomedical and Clinical Sciences "Luigi Sacco", Università degli Studi di Milano, Milan, Italy.

Background: Epidemiology of dysphagia and its drivers in obstructive sleep apnea (OSA) are poorly understood. The study aims to investigate the prevalence of dysphagia symptoms and their association with demographic and clinical factors in patients with OSA.

Methods: Patients with OSA referring to an Academic Sleep Outpatient Clinic were enrolled in a prospective study. Read More

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Copeptin, pro-atrial natriuretic peptide and pro-adrenomedullin as markers of hypoxic stress in patients with obstructive sleep apnea-a prospective intervention study.

Respir Res 2021 Apr 20;22(1):114. Epub 2021 Apr 20.

Clinic of Respiratory Medicine and Pulmonary Cell Research, University Hospital of Basel, Petersgraben 4, 4031, Basel, Switzerland.

Study Objectives: Obstructive sleep apnea (OSA) might lead to oxidative stress, inflammation and elevated circulating copeptin, proANP and proADM levels. We aimed to evaluate whether the levels of these prohormones are higher in patients with OSA and whether they might change under continuous positive airway pressure (CPAP) therapy, serving as potential proxies for the diagnosis and therapy-response in OSA.

Methods: A total of 310 patients with suspicion of OSA were recruited. Read More

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Management of respiratory complications and rehabilitation in individuals with muscular dystrophies: 1st Consensus Conference report from UILDM - Italian Muscular Dystrophy Association (Milan, January 25-26, 2019).

Acta Myol 2021 Mar 31;40(1):8-42. Epub 2021 Mar 31.

Neurorehabilitation Unit, the NEMO Clinical Center in Milan, University of Milan, Italy.

Respiratory complications are common in the patient with muscular dystrophy. The periodic clinical and instrumental respiratory evaluation is extremely important. Despite the presence in the literature of updated guidelines, patient associations often report lack of knowledge of these pathologies, particularly in peripheral hospitals. Read More

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Comparing respiratory polygraphy with pulse transit time analysis versus overnight polysomnography in the diagnosis of obstructive sleep apnoea in children.

Sleep Med 2021 May 1;81:457-462. Epub 2021 Mar 1.

FHKAM(Otolaryngology), Department of Otolaryngology, Tuen Mun Hospital, Hong Kong.

Objective: Obstructive sleep apnea syndrome in children is associated with significant morbidity. Polysomnography is the main diagnostic tool but is time consuming and requires skilled manpower to supervise the patient overnight and hence long referral to diagnosis time. However, there are limitations and underestimation of the apnoea hyponea index (AHI) with alternative home sleep apnoea testing (HSAT), such as type 3 respiratory polygraphy (RP). Read More

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Usefulness of sleep events detection using a wrist worn peripheral arterial tone signal device (WatchPAT™) in a population at low risk of obstructive sleep apnea.

J Sleep Res 2021 Apr 12:e13352. Epub 2021 Apr 12.

Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.

Due to the high prevalence of obstructive sleep apnea (OSA), it is recommended to use in-laboratory polysomnography (PSG) or a home sleep apnea test (HSAT) in uncomplicated adult subjects at high risk of OSA. The aims of the present study were to compare a HSAT device, a wrist worn peripheral arterial tone signal device (WatchPAT™-200 [WP]) with PSG and respiratory polygraphy (RP) in a low-risk population of OSA. A total of 47 adult subjects at low risk of OSA were simultaneously examined with the three different approaches in a single night. Read More

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The role of morphometric and respiratory factors in predicting the severity and evolution of urinary symptoms in patients with obstructive sleep apnea syndrome.

Sleep Breath 2021 Mar 16. Epub 2021 Mar 16.

Surgery Section, Universidad de León, León, Spain.

Objectives: To assess the severity, evolution, and behaviour of several urinary symptoms in patients with obstructive sleep apnea syndrome (OSAS) before and after the treatment with continuous positive airway pressure (CPAP).

Methods: A prospective study was performed on patients with a recent diagnosis of sleep apnea confirmed by nocturnal sleep polygraphy and absence of medical urological past history. The symptom incidence was analysed seeking predictive factors for initial nocturia, nocturnal polyuria (NP), and unfavourable International Prostate Symptoms Score (IPSS) before and after a 1-year period of treatment using a CPAP device. Read More

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Normal values for respiratory sleep polygraphy in children aged 4 to 9 years at 2,560 m above sea level.

J Sleep Res 2021 Mar 15:e13341. Epub 2021 Mar 15.

ENT, Pontifical Xavierian University, Bogota, Colombia.

Obstructive sleep apnea syndrome affects 1%-4% of all children worldwide. Currently, diagnosis of obstructive sleep apnea is based on sea-level guidelines, without taking into account the altitude at which the populations live. It has been shown that at 3,200 m of altitude there is an increase in obstructive events in healthy children aged 7 to 16 years; on the other hand, it is known that SpO dispersion between individuals becomes wider as altitude increases, a phenomenon that is more marked during sleep. Read More

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Comparison of the Apnea-Hypopnea Index Determined by a Peripheral Arterial Tonometry-Based Device With That Determined by Polysomnography - Results From a Multicenter Study.

Circ Rep 2020 Oct 16;2(11):674-681. Epub 2020 Oct 16.

Department of Cardiovascular Medicine, Saitama Medical Center, Jichi Medical University Saitama Japan.

Sleep disordered breathing (SDB) is prevalent and associated with increased mortality in patients both with and without cardiovascular disease (CVD). Many portable monitoring devices, including peripheral arterial tonometry (PAT)-based devices, have been developed. Although previous studies have demonstrated that the apnea-hypopnea index (AHI) determined by PAT devices (pAHI) is strongly correlated with AHI determined by polysomnography (AHI-PSG), no data have been reported from a Japanese patient population or patients with CVD. Read More

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October 2020

Prevalence of sleep apnea and daytime sleepiness in professional truck drivers.

Sleep Med 2021 May 16;81:136-143. Epub 2021 Feb 16.

Helsinki Sleep Clinic, Vitalmed Research Centre, Helsinki, Finland; Department of Clinical Neurosciences, University of Helsinki, Finland.

Introduction: The prevalence of obstructive sleep apnea (OSA) among professional truck drivers has varied from 28 to 78% in previous studies. In this study we wanted to estimate the prevalence of OSA and OSA with both subjectively measured sleepiness and objectively measured ability to stay awake (ie obstructive sleep apnea syndrome, OSAS) among professional truck drivers in Finland.

Subjects And Methods: Altogether 2066 professional truck drivers received a structured questionnaire. Read More

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Quality of poly(somno)graphy recordings in children.

J Sleep Res 2021 Mar 5:e13241. Epub 2021 Mar 5.

Pediatric Noninvasive Ventilation and Sleep Unit, AP-HP, Hôpital Necker-Enfants Malades, Paris, France.

The aim of the study was to assess the scorability of the signals of four poly(somno)graphy devices and transcutaneous carbon dioxide tracings (PtcCO ) of one device in children. The presence (0%, < 25%, 25%-50%, 50%-75%, 75%-99%, 100% of recording time) and quality (bad, average, good) of the signal of each sensor were analysed. During a 5-month period, 364 poly(somno)graphies were performed in 12 different hospital units. Read More

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Comparison of Frequency and Severity of Sleep-Related Breathing Disorders in Children with Simple Obesity and Paediatric Patients with Prader-Willi Syndrome.

J Pers Med 2021 Feb 18;11(2). Epub 2021 Feb 18.

Department of Endocrinology and Diabetology, The Children's Memorial Health Institute, Al. Dzieci Polskich 20, 04-730 Warsaw, Poland.

Sleep-related breathing disorders (SRBDs) can be present in children with simple obesity and with Prader-Willi syndrome (PWS) and influence an individual diagnostic and treatment approach. We compared frequency and severity of SRBDs in children with simple obesity and with PWS, both without and on recombinant human growth hormone (rhGH) treatment, and correlation of SRBDs with insulin resistance tests. A screening polysomnography-polygraphy (PSG), the oral glucose tolerance test (OGTT) and homeostasis model assessment of insulin resistance (HOMA-IR) were analysed in three groups of patients-with simple obesity (group 1, = 30, mean age 14. Read More

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February 2021

Mood, sleepiness, and weight gain after three years on CPAP therapy for sleep apnoea.

Eur Clin Respir J 2021 Feb 17;8(1):1888394. Epub 2021 Feb 17.

Division of Medicine, Department of Pulmonary Diseases, Turku University Hospital, Turku, Finland.

The prevalence of obstructive sleep apnoea syndrome (OSAS) keeps on rising. Daytime sleepiness resulting from fragmented sleep is the prime symptom, and obesity the major risk factor for OSAS. Quality of life with OSAS is often affected by depressive symptoms and anxiety. Read More

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February 2021

Sex differences in the association between arterial hypertension, blood pressure, and sleep apnea in the general population.

J Clin Sleep Med 2021 May;17(5):1057-1066

Ghent University, Faculty of Medicine and Health Sciences, Department of Internal Medicine and Pediatrics, Ghent, Belgium.

Study Objectives: To assess sex-related differences in the relationship between hypertension (HT), blood pressure (BP), and sleep apnea in the general population.

Methods: We performed home polygraphy in a cohort of 1809 men and women in the general population. Office BP was measured. Read More

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Diaphragmatic dysfunction at the first visit to a chest diseases outpatient clinic in 500 patients with amyotrophic lateral sclerosis.

Muscle Nerve 2021 05 25;63(5):683-689. Epub 2021 Feb 25.

Istanbul Faculty of Medicine, Department of Pulmonary Medicine, Istanbul University, Istanbul, Turkey.

Introduction: In this study, we aimed to evaluate diaphragmatic dysfunction (DD) by using a practical approach in patients with amyotrophic lateral sclerosis (ALS) at the first visit to a chest diseases outpatient clinic.

Methods: Patients with ALS seen in our outpatient clinic for the past 5 y and followed up for at least 1 y, were retrospectively evaluated. Having at least one of the following three criteria was accepted as DD: (a) paradoxical abdominal movement (PAM), (b) sitting-supine forced vital capacity (FVC) difference ≥ 20%, (c) sitting-supine arterial oxygen saturation measured by pulse oximetry (SpO ) difference ≥ 4%. Read More

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A one-arm surgical trial of obstructive sleep apnea (OSA) patients before and 12 months after Bilateral Internal Ramus Distraction of the mandible (BIRD).

Sleep Med 2021 Apr 20;80:57-65. Epub 2021 Jan 20.

Oral and Maxillofacial Department, Pneumology Department, Neurophysiology Department, Instituto de Investigación Hospital Universitario de La Princesa (IISP), Universidad Autónoma de Madrid, Madrid, Spain.

Background: An innovative approach for the primary and definitive treatment of obstructive sleep apnea (OSA) in adult patients is presented: Bilateral Internal Ramus Distraction of the mandible (BIRD), which is a slow, progressive and more stable procedure to advance the mandibular bone. This study investigated whether this surgical approach is useful to cure OSA.

Methods: Study design was of an interventional (surgical) one-arm trial of OSA patients assessed before and 12 months after BIRD. Read More

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Clinical Characteristics of Hypertensive Patients with Obstructive Sleep Apnoea Syndrome Developing Different Types of Left Ventricular Geometry.

Biomed Res Int 2021 23;2021:6631500. Epub 2021 Jan 23.

Department of Internal Medicine, Medical University of Lublin, Staszica 16, 20-081 Lublin, Poland.

Objective: The objective of the study was to compare polygraphic parameters and selected laboratory parameters in patients with obstructive sleep apnoea (OSA) who develop various types of left ventricular (LV) geometry. . The research covered 122 patients with obstructive sleep apnoea and coexisting effectively treated systemic hypertension (95 men, 27 women, average age: 54 ± 10. Read More

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January 2021

Clinical screening tools for obstructive sleep apnea in a population with atrial fibrillation: a diagnostic accuracy trial.

J Clin Sleep Med 2021 May;17(5):1015-1024

Department of Respiratory and Sleep Medicine, Royal North Shore Hospital, Sydney, Australia.

Study Objectives: Although obstructive sleep apnea (OSA) is a known risk factor for atrial fibrillation (AF), there is a paucity of data around its diagnosis and management in patients with AF. The objectives of this study were to compare the diagnostic accuracy of commonly used OSA screening tools in an AF population, including a level 3 portable sleep study device, and to examine the epidemiology of OSA in a hospital cohort with AF.

Methods: One hundred seven patients with AF recruited from 2 tertiary centers underwent a panel of OSA screening tools and in-laboratory polysomnography in randomized order. Read More

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Home respiratory polygraphy in obstructive sleep apnea syndrome in children: Comparison with a screening questionnaire.

Int J Pediatr Otorhinolaryngol 2021 Apr 27;143:110635. Epub 2021 Jan 27.

Pediatric Pulmonary Unit, Division of Pediatric Specialties, Department of Pediatrics, Gynecology and Obstetrics, University Hospitals of Geneva and University of Geneva, Switzerland. Electronic address:

Objectives: The prevalence of obstructive sleep apnea syndrome (OSAS) in children referred for sleep-disordered breathing reaches up to 59%. We aimed to test the adequacy of a questionnaire compared to home respiratory polygraphy (HRP), in 45 subjects (5-16 years-old), without maxillofacial malformations nor other comorbidities, presenting with symptoms compatible with OSAS.

Methods: All children passed a 12-items questionnaire (Obstructive Airway Child test: OACT) and the HRP. Read More

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Effect of early sleep apnoea treatment with adaptive servo-ventilation in acute stroke patients on cerebral lesion evolution and neurological outcomes: study protocol for a multicentre, randomized controlled, rater-blinded, clinical trial (eSATIS: early Sleep Apnoea Treatment in Stroke).

Trials 2021 Jan 22;22(1):83. Epub 2021 Jan 22.

Department of Neurology, Bern University Hospital (Inselspital) and University of Bern, Bern, Switzerland.

Background: Sleep-disordered breathing (SDB) is highly prevalent in acute ischaemic stroke and is associated with worse functional outcome and increased risk of recurrence. Recent meta-analyses suggest the possibility of beneficial effects of nocturnal ventilatory treatments (continuous positive airway pressure (CPAP) or adaptive servo-ventilation (ASV)) in stroke patients with SDB. The evidence for a favourable effect of early SDB treatment in acute stroke patients remains, however, uncertain. Read More

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January 2021