J Pediatr 2021 May 10. Epub 2021 May 10.
Department of Paediatrics and Child Health, University College Cork, Cork, Ireland; Division of Endocrinology and Diabetes, The Children's Hospital of Philadelphia, Philadelphia, USA; Perelman School of Medicine, University of Pennsylvania, Philadelphia.
Objectives: | To determine the weight, BMI, cardiometabolic and gastrointestinal effects of GLP-1 receptor agonists in children with obesity.
Study Design: | Web of Science, PubMed/MEDLINE, and Scopus databases from 01/01/1994-01/01/2021 for randomized control trials examining the weight, BMI, cardiometabolic or gastrointestinal effects of GLP-1 receptor agonists in children and adolescents with obesity. Data were extracted by two independent surveyors and a random effects model was applied to meta-analyze generic inverse variance outcomes. Read More