Am J Surg Pathol 2021 Mar 24. Epub 2021 Mar 24.
Mount Sinai Hospital Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto Lakeridge Health, Oshawa Royal Victoria Regional Health Centre, Barrie Grey Bruce Health Services, Owen Sound Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada.
Venous invasion (VI) is a powerful prognostic factor in colorectal cancer (CRC) that is widely underreported. The ability of elastin stains to improve VI detection is now recognized in several international CRC pathology protocols. However, concerns related to the cost and time required to perform and evaluate these stains in addition to routine hematoxylin and eosin (H&E) stains remains a barrier to their wider use. Read More