3,259 results match your criteria represented urinary

Age and sex-specific prevalence of serious bacterial infections in febrile infants ≤60 days, in Sweden.

Acta Paediatr 2021 Jul 26. Epub 2021 Jul 26.

Department of Pediatrics, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Aim: To describe age and sex-specific prevalence of serious bacterial infections (SBI: urinary tract infection, bacteremia, meningitis) among febrile infants ≤60 days in Sweden.

Methods: Retrospective study in 4 Pediatric Emergency Departments from 2014-2017, in previously healthy, full-term infants ≤60 days with fever without a source.

Results: Of the 1701 included infants, 214 (12. Read More

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Optimal clamping time in meatotomy procedure for children with meatal stenosis: Experience with 120 cases.

Arch Ital Urol Androl 2021 Jun 29;93(2):244-247. Epub 2021 Jun 29.

Urology Research Center, Al-Thora General Hospital, Department of Urology, Ibb University of Medical Since, Ibb.

Objective: During meatotomy procedure for children with meatal stenosis (MS), a straight clamp used as a hemostat on the ventrum of the meatus before incised with scissors for clamping and holding bleeding from the site of operation. The aim of this study was to evaluate the optimum clamping time for meatotomy in children with MS.

Materials And Methods: All the patients with MS between 2014 to 2019 were enrolled in this retrospective study. Read More

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Cauda Equina Syndrome: Poor Recovery Prognosis Despite Early Treatment.

Spine (Phila Pa 1976) 2021 Jul 7. Epub 2021 Jul 7.

Département de Neurochirurgie, Hôpital de Bretonneau, Tours, France INSERM U1253, faculté de Tours, France, Tours.

Study Design: A prospective patient' database operated on a cauda equina syndrome (CES).

Objective: The aim of our study was to identify prognosis factors for favorable functional recovery after CES.

Summary Of Background: CES is a neurologic impairment of variable symptoms associating urinary, bowel, and sexual dysfunctions with or without motor or sensitive deficits caused by nerve root compression of the cauda equina. Read More

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"Nerve-sparing" laparoscopic treatment of parametrial ectopic pregnancy.

Fertil Steril 2021 Jul 9. Epub 2021 Jul 9.

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

Objective: To demonstrate laparoscopic surgical management of parametrial ectopic pregnancy.

Design: Video presentation of laparoscopic nerve-sparing treatment of parametrial pregnancy.

Setting: Tertiary university center. Read More

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[Cystoscopic and morphological features of chronic recurrent papillomavirus cystitis].

Urologiia 2021 Jun(3):45-49

Rostov State Medical University, Rostov-on-Don, Russia.

Introduction: Chronic recurrent cystitis (CRC) is a common disease in the female population and a serious medical problem. There are not enough data about etiology of this desiase and effective treatment.

Objective: To increase the accuracy of the differential diagnosis of bacterial and papillomavirus chronic recurrent cystitis. Read More

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Characterization of Urothelial Inclusions in Male Wistar Han Rats Treated Orally With the Novel α2A-Adrenoceptor Agonist Tasipimidine.

Toxicol Pathol 2021 Jul 9:1926233211027471. Epub 2021 Jul 9.

Orion Corporation, Orion Pharma, Espoo, Finland.

Intracellular inclusions were observed in urinary bladder epithelium of male Wistar rats, following oral treatment with high doses of the α-adrenoceptor agonist tasipimidine for 28 days. No cell death or inflammation was associated with the brightly eosinophilic inclusions. Electron microscopy (EM) studies showed that the inclusions represented intact or fragmented red blood cells (RBC) resulting from erythrophagocytosis, further supported by the presence of iron in urothelial cells. Read More

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activity of cefiderocol and comparators against isolates of Gram-negative pathogens from a range of infection sources: SIDERO-WT-2014-2018 studies in France.

JAC Antimicrob Resist 2021 Jun 14;3(2):dlab081. Epub 2021 Jun 14.

Laboratory of Bacteriology, School of Medicine and University Hospital, Strasbourg, France.

Objectives: Over recent years, France has experienced an increase of infections caused by carbapenem-resistant Gram-negative (GN) pathogens. Cefiderocol is approved in Europe for the treatment of aerobic GN infections in adults with limited treatment options. This study evaluated the activity of cefiderocol and comparators against GN clinical isolates from France. Read More

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Paraplegia due to medullary compression caused by a large cell neuroendocrine carcinoma of the urinary bladder: A case report.

Ann Med Surg (Lond) 2021 Jul 6;67:102475. Epub 2021 Jun 6.

Department of Urology, Sahloul Hospital, Sousse, Tunisia.

Background: Neuroendocrine carcinomas of the urinary bladder are rare tumors, estimated at less than 1% of urinary bladder malignancies. They are mainly represented by small cell neuroendocrine carcinoma, while large cell neuroendocrine carcinoma (LCNEC) is rarely reported.

Case Presentation: We report a case of a 49-year-old man presenting paraplegia caused by a metastatic urinary bladder LCNEC, which was managed with palliative external beam radiotherapy (EBRT) associated with MVAC chemotherapy, including methotrexate, vinblastine sulfate, doxorubicin hydrochloride (Adriamycin), and cisplatin. Read More

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Resistance Patterns from Urine Cultures in Children Aged 0 to 6 Years: Implications for Empirical Antibiotic Choice.

Infect Drug Resist 2021 23;14:2341-2348. Epub 2021 Jun 23.

Infectious Disease Unit, Meyer Children's University Hospital, Florence, Italy.

Purpose: Urinary tract infection (UTI) is a frequent disorder of childhood, caused mainly by Gram negative . The aim of this study is to evaluate etiology and antimicrobial susceptibility patterns of bacterial isolates in urine cultures of children under the age of 6 and to analyze the relationship between previous hospitalization or antibiotic prescriptions and antimicrobial resistance rates.

Patients And Methods: A retrospective study on positive urine cultures from 13 public laboratories in Tuscany, Italy was conducted. Read More

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Protective prospects of eco-friendly synthesized selenium nanoparticles using Moringa oleifera or Moringa oleifera leaf extract against melamine induced nephrotoxicity in male rats.

Ecotoxicol Environ Saf 2021 Sep 23;221:112424. Epub 2021 Jun 23.

Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Zagazig University, El-Sharkia Province 44511, Egypt.

Nanotechnology is used in a wide range of applications, including medical therapies that precisely target disease prevention and treatment. The current study aimed firstly, to synthesize selenium nanoparticles (SeNPs) in an eco-friendly manner using Moringa oleifera leaf extract (MOLE). Secondly, to compare the protective effects of green-synthesized MOLE-SeNPs conjugate and MOLE ethanolic extract as remedies for melamine (MEL) induced nephrotoxicity in male rats. Read More

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September 2021

FUrTIHF: French Urinary Tract Infections in Healthcare Facilities French Urinary Tract Infections in Healthcare Facilities: 5-year historic cohort 2014-2018.

J Hosp Infect 2021 Jun 21. Epub 2021 Jun 21.

EpiDcliC, Unité de santé publique, SIMEES, CHRU de Tours, France; Faculté de médecine, Université de Tours, France; CIAFU Comité d'infectiologie de L'Association Française d'Urologie, France. Electronic address:

Background: Urinary tract infections (UTIs) are common and diverse. Even when not severe UTIs regularly lead to hospitalization, but their hospital burden remains unknown. This study aimed to estimate the national incidence of hospitalized UTIs in France. Read More

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Case of pheochromocytoma mimicking MINOCA.

BMJ Case Rep 2021 Jun 21;14(6). Epub 2021 Jun 21.

Cardiology Department, Buckinghamshire Healthcare NHS Trust, Aylesbury, Buckinghamshire, UK.

We present a 52-year-old woman who was admitted to the emergency department with a short history of palpitations, sweating and nausea. An electrocardiogram (ECG) that was performed suggested inferolateral ischaemia with a significant troponin rise. The patient underwent an invasive coronary angiogram that showed mild non-obstructive coronary disease. Read More

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Direct and indirect costs and cost-driving factors of Tuberous sclerosis complex in children, adolescents, and caregivers: a multicenter cohort study.

Orphanet J Rare Dis 2021 06 21;16(1):282. Epub 2021 Jun 21.

Division of Pediatric Epileptology, Centre for Paediatrics and Adolescent Medicine, University Hospital Heidelberg, Heidelberg, Germany.

Background: Tuberous sclerosis complex (TSC), a multisystem genetic disorder, affects many organs and systems, characterized by benign growths. This German multicenter study estimated the disease-specific costs and cost-driving factors associated with various organ manifestations in TSC patients.

Methods: A validated, three-month, retrospective questionnaire was administered to assess the sociodemographic and clinical characteristics, organ manifestations, direct, indirect, out-of-pocket, and nursing care-level costs, completed by caregivers of patients with TSC throughout Germany. Read More

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New data on the metabolism of chloromethylisothiazolinone and methylisothiazolinone in human volunteers after oral dosage: excretion kinetics of a urinary mercapturic acid metabolite ("M-12").

Arch Toxicol 2021 Aug 21;95(8):2659-2665. Epub 2021 Jun 21.

Institute for Occupational, Social and Environmental Medicine, Medical Faculty, RWTH Aachen University, Pauwelsstrasse 30, 52074, Aachen, Germany.

Methylisothiazolinone (MI) as well as the mixture of chloromethylisothiazolinone/methylisothiazolinone [MCI/MI (3:1)] are biocides that are used in a variety of products of every-day life. Due to the skin sensitizing properties of these biocides, their use has come under scrutiny. We have previously examined the human metabolism of MI and MCI after oral dosage of isotope-labelled analogues in human volunteers and confirmed N-methylmalonamic acid to be a major, but presumably unspecific human urinary metabolite. Read More

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Urogenital fascia anatomy study in the inguinal region of 10 formalin-fixed cadavers: new understanding for laparoscopic inguinal hernia repair.

BMC Surg 2021 Jun 17;21(1):295. Epub 2021 Jun 17.

First Department of General Surgery, Shaanxi Provincial People's Hospital, Xi'an, Shaanxi, 710000, China.

Purpose: To investigate the urogenital fascia (UGF) anatomy in the inguinal region, to provide anatomical guidance for laparoscopic inguinal hernia repair (LIHR).

Methods: The anatomy was performed on 10 formalin-fixed cadavers. The peritoneum and its deeper fascial tissues were carefully dissected. Read More

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Cyclophosphamide-associated bladder cancers and considerations for survivorship care: A systematic review.

Urol Oncol 2021 Jun 13. Epub 2021 Jun 13.

Harvard Medical School, 25 Shattuck Street, Boston, MA 02115; Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, 02215; Division of Urologic Surgery, Brigham and Women's Hospital, 45 Francis Street, Boston, MA, 02115. Electronic address:

Purpose: We performed a systematic review to assess the clinical features of cyclophosphamide-associated bladder cancer.

Materials And Methods: MEDLINE, Web of Science, and Cochrane Library were searched from inception to August 2020 according to PRISMA guidelines. Studies that associated bladder cancer with prior cyclophosphamide use on an individual level were included. Read More

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Continuous renal replacement therapy in sepsis-associated acute kidney injury: Effects on inflammatory mediators and coagulation function.

Asian J Surg 2021 Jun 1. Epub 2021 Jun 1.

Department of Infectious Disease, Affiliated Hospital of Southwest Medical University, Luzhou City, Sichuan Province, 646000, China. Electronic address:

Background: To explore the effect of continuous renal replacement therapy (CRRT) in patients with sepsis-associated acute kidney injury (SA-AKI) with the Acute Kidney Injury Network Classification III and its effect on inflammatory mediators and coagulation function.

Methods: We evaluated 90 patients who were diagnosed with sepsis and treated at our hospital. Forty patients received CRRT (group A) and the remainder received routine therapy (group B). Read More

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Safety and efficacy of holmium laser enucleation of prostate as salvage procedure for persistent or recurrent lower urinary tract symptoms secondary to bladder outlet obstruction after prior prostate artery embolization: a match analysis.

World J Urol 2021 Jun 3. Epub 2021 Jun 3.

Department of Urology, University of Miami Miller School of Medicine, Miami, FL, USA.

Purpose: To evaluate safety and efficacy of Holmium laser enucleation of Prostate (HoLEP) for management of persistent or recurrent lower urinary tract symptoms after prior prostate artery embolization (PAE). We also evaluated histopathological changes in prostate after PAE.

Methods: Ten patients who underwent HoLEP after prior PAE were matched according to age, weight of resected prostate tissue, and anticoagulation status in 1:2 ratio with patients who underwent HoLEP without prior PAE by a researcher who was blinded to patient's outcome at the time of matching. Read More

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Direct and indirect costs and cost-driving factors in adults with tuberous sclerosis complex: a multicenter cohort study and a review of the literature.

Orphanet J Rare Dis 2021 06 2;16(1):250. Epub 2021 Jun 2.

Epilepsy Center Frankfurt Rhine-Main, Department of Neurology, Goethe-University Frankfurt, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.

Background: Tuberous sclerosis complex (TSC) is a monogenetic, multisystem disorder characterized by benign growths due to TSC1 or TSC2 mutations. This German multicenter study estimated the costs and related cost drivers associated with organ manifestations in adults with TSC.

Methods: A validated, three-month, retrospective questionnaire assessed the sociodemographic and clinical characteristics, organ manifestations, direct, indirect, out-of-pocket (OOP), and nursing care-level costs among adult individuals with TSC throughout Germany from a societal perspective (costing year: 2019). Read More

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Epidemiological and clinical characteristics of stone composition: a single-center retrospective study.

Urolithiasis 2021 May 31. Epub 2021 May 31.

Department of Urology, The Second Hospital of Tianjin Medical University, 23 Pingjiang Road, Hexi District, Tianjin, People's Republic of China.

The aim of the study was to investigate the epidemiological characteristics of stone components in patients with urolithiasis and analyze the associations between stone components with patients' clinical characteristics. A total of 7126 patients with urolithiasis between July 2005 and June 2020 were retrospectively analyzed. In this research, calcium oxalate stones (74. Read More

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Current Insights into the Steroidal Module of the Athlete Biological Passport.

Int J Sports Med 2021 May 28. Epub 2021 May 28.

Center for Preventive Doping Research - Institute of Biochemistry, German Sport University Cologne, Cologne, Germany.

For decades, the class of anabolic androgenic steroids has represented the most frequently detected doping agents in athletes' urine samples. Roughly 50% of all adverse analytical findings per year can be attributed to anabolic androgenic steroids, of which about 2/3 are synthetic exogenous steroids, where a qualitative analytical approach is sufficient for routine doping controls. For the remaining 1/3 of findings, caused by endogenous steroid-derived analytical test results, a more sophisticated quantitative approach is required, as their sheer presence in urine cannot be directly linked to an illicit administration. Read More

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Evaluation of sensitivity profiles to fosfomycin in bacterial urine samples from outpatients.

Eur J Obstet Gynecol Reprod Biol 2021 Jul 14;262:184-187. Epub 2021 May 14.

Statistics Department, Fluminense Federal University, 24210-200, Niteroi, Brazil.

Objective: To evaluate and compare the susceptibilities of bacteria found in outpatient cultures to fosfomycin and other main antibiotics commonly available in clinical practice.

Study Design: A retrospective cross-sectional study was conducted using 2,673 positive urine cultures collected between 2014 and 2017 at private laboratories located in the cities of Niterói and São Gonçalo. Susceptibilities to fosfomycin and other antibiotics were tested using the McNemar test with the level of significance set at 5 %. Read More

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In vitro activity of cefiderocol and comparators against isolates of Gram-negative pathogens from a range of infection sources: SIDERO-WT-2014-2018 studies in Italy.

J Glob Antimicrob Resist 2021 06 18;25:390-398. Epub 2021 May 18.

Department of Biomedical and Biotechnological Sciences, Università di Catania, Via Santa Sofia 97, I-95123 Catania, Italy.

Objectives: Antimicrobial resistance, particularly carbapenem resistance, in Gram-negative pathogens poses a significant healthcare threat. Carbapenem resistance rates in Italy are among the highest in Europe. We report the in vitro activity of cefiderocol, a novel siderophore cephalosporin, and comparator antibiotics against Gram-negative isolates from Italy as part of the SIDERO-WT studies. Read More

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Soft Urinary Bladder Phantom for Endoscopic Training.

Ann Biomed Eng 2021 May 17. Epub 2021 May 17.

Cyber Valley Research Group, Institute of Physical Chemistry, University of Stuttgart, Pfaffenwaldring 55, 70569, Stuttgart, Germany.

Bladder cancer (BC) is the main disease in the urinary tract with a high recurrence rate and it is diagnosed by cystoscopy (CY). To train the CY procedures, a realistic bladder phantom with correct anatomy and physiological properties is highly required. Here, we report a soft bladder phantom (FlexBlad) that mimics many important features of a human bladder. Read More

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Morbidity and mortality after open radical cystectomy and ileal diversion - 10 years experience and a comprehensive assessment in a single tertiary center.

Neoplasma 2021 May 17. Epub 2021 May 17.

Department of Urology, University Hospital of Motol , Second Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

Open radical cystectomy (ORC) remains the gold standard for the treatment of muscle-invasive and high-risk non-muscle invasive bladder cancer unsuitable for bladder preservation techniques. Despite improvements in operative technique and perioperative care, it continues to be associated with significant complications. We analyzed our series of prospectively collected data of patients that underwent ORC at a tertiary referral academic center and evaluated early and late postoperative complications and mortality. Read More

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Epidemiology of biopsy-proven glomerulonephritis in the past 25 years in the North-Eastern area of Romania.

Int Urol Nephrol 2021 May 15. Epub 2021 May 15.

Nephrology Clinic, Dialysis and Renal Transplant Center, 'C.I. Parhon' University Hospital, and "Grigore T. Popa" University of Medicine, Iasi, Romania.

Purpose: The aim of this retrospective study was: to analyze the epidemiological patterns of the kidney disease based on clinical and histological features in a single-center in the N-E region of Romania, between 2011 and 2019 and to compare the biopsy results with the others periods, as well as the results from other countries.

Methods: We studied 442 renal biopsies. The indications for renal biopsy were represented by the clinical features: nephrotic syndrome, nephritic syndrome, asymptomatic urinary abnormalities, acute kidney injury, and chronic kidney disease of unknown etiology. Read More

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Abdominal radical trachelectomy as fertility-sparing management for early stages of cervical cancer: Our experience in 18 cases.

Exp Ther Med 2021 Jul 23;22(1):674. Epub 2021 Apr 23.

First Obstetrics and Gynecology Clinic, 'George Emil Palade' University of Medicine, Pharmacy, Science and Technology, 540136 Târgu Mures, Romania.

The aim of this study was to present our experience of 18 cases of abdominal radical trachelectomy (ART), including 5 performed during pregnancy, analyzing patient selection, surgical complications, and oncological and obstetrical outcomes. This reproductive study included all early stage cervical cancer patients referred for ART at the 1st Obstetrics and Gynecology Clinic of the Emergency Clinical County Hospital Targu Mures, between 2010 and 2020. A total of 19 women were considered for ART, and only 1 case required conversion to radical hysterectomy. Read More

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Primary squamous cell carcinoma of the urinary bladder presenting as an inguinal mass.

SA J Radiol 2021 29;25(1):2048. Epub 2021 Mar 29.

Department of Radiology, St. Vincent's Medical Center, Bridgeport, CT, The United States of America.

This report involves a rare case of a 74-year-old man who presented with a progressively increasing swelling in the right groin, which represented a squamous cell bladder carcinoma herniating into the right inguinal canal. The manuscript discusses the role of multimodality imaging in bladder carcinoma presenting as an inguinoscrotal hernia. The patient subsequently underwent treatment with a chemotherapy regimen consisting of 5-fluorouracil and mitomycin, which was extrapolated from squamous cell carcinoma of the anal canal, and responded well. Read More

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Carnitine/organic cation transporter 1 precipitates the progression of interstitial fibrosis through oxidative stress in diabetic nephropathy in mice.

Sci Rep 2021 Apr 27;11(1):9093. Epub 2021 Apr 27.

Department of Nephrology and Laboratory Medicine, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.

Carnitine/organic cation transporter 1 (OCTN1) is the only known uptake transporter for ergothioneine which is a food-derived strong antioxidant amino acid that is absorbed by OCTN1. We previously reported the roles of OCTN1/ergothioneine in the progression of kidney fibrosis in ischemic kidney disease. In this study, we evaluated the roles of OCTN1 in the progression of diabetic kidney disease. Read More

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Levofloxacin Versus Ciprofloxacin in the Treatment of Urinary Tract Infections: Evidence-Based Analysis.

Front Pharmacol 2021 8;12:658095. Epub 2021 Apr 8.

Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China.

Urinary tract infections (UTIs) are one of the most common bacterial infections acquired both in community and hospital. Fluoroquinolones, represented by levofloxacin and ciprofloxacin, are widely used for treatment of UTIs. However, it remains controversial for the comparison between the 2 drugs, which propelled us to conduct the first evidence-based research on this topic. Read More

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