361,086 results match your criteria reported cases

IgM-enriched immunoglobulin in COVID-19: Case series of 15 severely ill SARS-CoV-2-infected patients.

Int Immunopharmacol 2021 Jul 23;99:107998. Epub 2021 Jul 23.

Chronic Respiratory Diseases Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran; Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:

The healthcare system in Iran, like most around the world, is managing thousands of patients hospitalised with COVID-19. In Iran, in-hospital mortality is in the region of 25%, rising to 50-60% in patients admitted to intensive care. Hyperinflammation, characterised by cytokine storm, appears to be a hallmark of severe COVID-19 and to date only the anti-inflammatory drug dexamethasone has been shown to reduce mortality in those hospitalised with the disease. Read More

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Levenberg-Marquardt multi-classification using hinge loss function.

Neural Netw 2021 Jul 12;143:564-571. Epub 2021 Jul 12.

Scientific Networking Division, Lawrence Berkeley National Laboratory, Berkeley, CA, United States of America. Electronic address:

Incorporating higher-order optimization functions, such as Levenberg-Marquardt (LM) have revealed better generalizable solutions for deep learning problems. However, these higher-order optimization functions suffer from very large processing time and training complexity especially as training datasets become large, such as in multi-view classification problems, where finding global optima is a very costly problem. To solve this issue, we develop a solution for LM-enabled classification with, to the best of knowledge first-time implementation of hinge loss, for multiview classification. Read More

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Online sexual harassment and depression in Chilean adolescents: Variations based on gender and age of the offenders.

Child Abuse Negl 2021 Jul 24;120:105219. Epub 2021 Jul 24.

School of Health in Social Sciences, University of Edinburgh, UK.

Background: Online sexual harassment in adolescence is associated with depressive symptoms. There is, however, a dearth of research investigating variability of symptom profiles in this population in relation to offender gender and age.

Objective: To identify the proportion of adolescents reporting online harassment by different types of offenders and compare their levels of depression. Read More

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Surgical resection of pulmonary crystal-storing histiocytosis with Sjögren's syndrome: A case report.

Int J Surg Case Rep 2021 Jul 14;85:106196. Epub 2021 Jul 14.

Department of Chest Surgery, Sasebo City General Hospital, 9-3 Hirase-cho, Sasebo, Nagasaki 857-8511, Japan. Electronic address:

Introduction And Importance: Crystal-storing histiocytosis (CSH) is a rare clinical entity characterized by an abnormal increase in the number of histiocytes with massive accumulation of crystallized immunoglobulins. Yano et al. reported only one case of gastric CSH associated with Sjögren's syndrome. Read More

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Chronic subdural hematoma-induced parkinsonism: A systematic review.

Clin Neurol Neurosurg 2021 Jul 21;208:106826. Epub 2021 Jul 21.

Department of Neurosurgery, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.

Background: Chronic subdural hematoma (CSDH) is one of the most common neurosurgical cases, especially in elderly individuals. Secondary parkinsonism due to CSDH is a rare entity. The mechanism of parkinsonism symptoms in chronic subdural hematoma has been suggested to include direct mechanical compression of the basal ganglia due to hematoma or indirectly through brain structure changes due to space lesions and vascular disorders. Read More

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Diplopia due to acquired Brown syndrome after COVID-19 infection.

J AAPOS 2021 Jul 24. Epub 2021 Jul 24.

Department of Ophthalmology, Ankara University, School of Medicine, Ankara, Turkey.

Coronavirus disease 2019 (COVID-19) is a multisystem, inflammatory condition usually presenting with respiratory symptoms, such as fever, shortness of breath, and severe cough. It may also present with ocular, neurological, and musculoskeletal manifestations. However, since the emergence of the disease in 2019, only a few cases with ocular involvement have been reported in the literature. Read More

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A disproportionate epidemic: COVID-19 cases and deaths among essential workers in Toronto, Canada.

Ann Epidemiol 2021 Jul 24. Epub 2021 Jul 24.

St. Michael's Hospital, University of Toronto, Toronto, Canada; Division of Infectious Diseases, Department of Medicine, University of Toronto, Toronto, Canada. Electronic address:

Shelter-in-place mandates and closure of non-essential businesses have been central to COVID19 response strategies including in Toronto, Canada. Approximately half of the working population in Canada are employed in occupations that do not allow for remote work suggesting potentially limited impact of some of the strategies proposed to mitigate COVID-19 acquisition and onward transmission risks and associated morbidity and mortality. We compared per-capita rates of COVID-19 cases and deaths from January 23, 2020 to January 24, 2021, across neighborhoods in Toronto by proportion of the population working in essential services. Read More

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Hemorrhoidectomy Versus Rubber Band Ligation in Grade III Hemorrhoidal Disease: A Large Retrospective Cohort Study With Long-term Follow-up.

Ann Coloproctol 2021 Jul 27. Epub 2021 Jul 27.

1Department of Surgery, Proctos Kliniek, Bilthoven, The Netherlands.

Purpose: Standard therapy for grade III hemorrhoids is rubber band ligation (RBL) and hemorrhoidectomy. The long-term clinical and patient-reported outcomes of these treatments in a tertiary referral center for proctology were evaluated.

Methods: A retrospective analysis was performed in all patients with grade III hemorrhoids who were treated between January 2013 and August 2018. Read More

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The prevalence of intra-tumoral and distant thrombi, as well as tumor-cell emboli in canine neoplasia.

Vet Comp Oncol 2021 Jul 27. Epub 2021 Jul 27.

Department of Companion Animal Clinical Studies, Faculty of Veterinary Science, University of Pretoria, Pretoria, South Africa.

Macroscopic thromboembolic disease has been associated with canine neoplasia, whereas prevalence studies of concurrent microthrombi and tumor-cell emboli are lacking. This retrospective study investigated microthrombi and tumor cell emboli by reviewing pathology records of dogs diagnosed with lymphoma, sarcoma, carcinoma and mast cell tumors with a concurrent description of thrombi or emboli. Pathology reports and medical records of cases with either tumor biopsies and/or post mortems with a diagnosis of neoplasia were reviewed for the presence of microthrombi, macrothrombi and/or tumor-cell emboli and the association with tumor type. Read More

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Lower serum 25(OH)D levels associated with higher risk of COVID-19 infection in U.S. Black women.

PLoS One 2021 27;16(7):e0255132. Epub 2021 Jul 27.

Slone Epidemiology Center at Boston University, Boston, Massachusetts, United States of America.

Objective: Limited evidence suggests that higher levels of serum vitamin D (25(OH)D) protect against SARS-CoV-2 virus (COVID-19) infection. Black women commonly experience 25(OH)D insufficiency and are overrepresented among COVID-19 cases. We conducted a prospective analysis of serum 25(OH)D levels in relation to COVID-19 infection among participants in the Black Women's Health Study. Read More

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The burden of scrub typhus in India: A systematic review.

PLoS Negl Trop Dis 2021 Jul 27;15(7):e0009619. Epub 2021 Jul 27.

Department of Infectious Diseases, Christian Medical College, Vellore, Tamil Nadu, India.

Background: Scrub typhus, a vector-borne zoonotic infection caused by the bacteria Orientia tsutsugamushi, is one of the most common and clinically important rickettsial infections worldwide. An estimated one million cases occur annually with a high case fatality rate. Although scrub typhus is a major public health threat in India, the burden and distribution remains unclear. Read More

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Clinical Presentations, Management and Outcomes of Rhino-Orbital-Cerebral Mucormycosis (ROCM) Following COVID-19: A Multi-Centric Study.

Ophthalmic Plast Reconstr Surg 2021 Jul 27. Epub 2021 Jul 27.

Ophthalmic Plastic Surgery Service, Kallam Anji Reddy Campus, L V Prasad Eye Institute, Hyderabad; Aditya Jyot Eye Hospital; Lokmanya Tilak Municipal Medical College and General Hospital, Mumbai; Kempegowda Institute of Medical Sciences, Bangalore, India; Manipal Hospital, Bangalore; P D Hinduja National Hospital and Medical Research Centre, Sir H N Reliance Foundation Hospital, Mumbai; Eye Hub Vision Care, Faridabad; and I-Plast Eye and Plastic Surgery Centre, Amritsar, India.

Purpose: To report clinical presentations and factors affecting outcomes in rhino-orbital-cerebral mucormycosis following COVID-19.

Methods: Retrospective multi-centric interventional case series of 58 eyes with rhino-orbital-cerebral mucormycosis. Demography, clinical parameters and management outcomes were noted. Read More

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Aquablation, Prostatic Urethral Lift, and Transurethral Water Vapor Therapy: A Comparison of Device Related Adverse Events in a National Registry.

J Endourol 2021 Jul 27. Epub 2021 Jul 27.

Maimonides Medical Center, 2042, Brooklyn, New York, United States;

Purpose: Aquablation, prostatic urethral lift (PUL), and transurethral water vapor therapy (TWVT) have demonstrated efficacy for the treatment of benign prostatic hyperplasia (BPH). Our objective was to describe device malfunctions and complications to help guide procedural selection and performance.

Materials And Methods: The Manufacturer and User Facility Device Experience (MAUDE) database was examined for reports related to the use of these three procedures for the treatment of BPH between January 1, 2015 and July 1, 2020. Read More

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Underreported Breast and Cervical Cancer Deaths Among Brought-In-Dead Cases in Zambia.

JCO Glob Oncol 2021 Jul;7:1209-1211

Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.

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Site-Specific Fragmentation of Green Fluorescent Protein Induced by Blue Light.

Biochemistry 2021 Jul 27. Epub 2021 Jul 27.

Lehrstuhl für Chemie der Biopolymere, Technische Universität München, Weihenstephaner Berg 3, 85354 Freising, Germany.

Green fluorescent protein (GFP) and related fluorescent proteins have multiple applications in cell biology, and elucidating their functions has been at the focus of biophysical research for about three decades. Fluorescent proteins can be bleached by intense irradiation, and a number of them undergo photoconversion. Rare cases have been reported where distant functional relatives of GFP exhibit UV-light-induced protein fragmentation. Read More

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Combined molecular and histologic end points inform cancer risk estimates for thyroid nodules classified as atypia of undetermined significance.

Cancer Cytopathol 2021 Jul 27. Epub 2021 Jul 27.

Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.

Background: Thyroid nodules classified as atypia of uncertain significance (AUS) on fine-needle aspiration cytology are heterogeneous. Prior studies reported a higher risk of noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP)/cancer among AUS nodules that had cytologic (AUS-C) versus architectural (AUS-A) atypia; however, such studies were generally confined to resected cohorts, introducing bias into risk calculations. The authors hypothesized that combined histologic and molecular end points would permit clinically meaningful calculations of NIFTP/malignancy risk among AUS nodules. Read More

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Estimating the transmissibility of hepatitis C: a modelling study in Yichang City, China.

J Viral Hepat 2021 Jul 27. Epub 2021 Jul 27.

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, School of Public Health, Xiamen University, Xiamen City, Fujian Province, People's Republic of China.

Yichang is a city in central China in the Hubei Province. This study aimed to estimate the dynamics of the transmissibility of hepatitis C using a mathematical model and predict the transmissibility of hepatitis C in 2030. Data of hepatitis C cases from 13 counties or districts (cities) in Yichang from 2008 to 2016 were collected. Read More

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An integrative histopathological and epigenetic characterization of primary intracranial mesenchymal tumors, FET:CREB-fused broadening the spectrum of tumor entities in comparison with their soft tissue counterparts.

Brain Pathol 2021 Jul 27:e13010. Epub 2021 Jul 27.

Department of Neuropathology, GHU Paris-Psychiatrie et Neurosciences, Sainte-Anne Hospital, Paris, France.

FET:CREB fusions have been described in a variety of tumors from various phenotypes. Recently, these fusion transcripts were reported in intracranial tumors, variably named intracranial mesenchymal myxoid tumors or angiomatoid fibrous histiocytomas. Controversy remains concerning the terminology for these tumors. Read More

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Pedicle screws implantation in polymethylmethacrylate construct to stabilise sixth lumbar vertebral body fracture in dogs: 5 cases (2015-2018).

E Gougeon P Meheust

J Small Anim Pract 2021 Jul 27. Epub 2021 Jul 27.

Clinique Vétérinaire Vétocéane, 9 allée Alphonse Fillion, 44120, Vertou, France.

Objectives: To assess the feasibility and outcome of pedicle screw implantation on sixth lumbar vertebral body fractures.

Materials And Methods: Dogs with sixth lumbar vertebral body fractures stabilised using L6 and L7 (±L5) pedicular implantation via a dorsal approach preferentially and conventional vertebral body implantation otherwise were reviewed. Coaptation was made with bone cement. Read More

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Characteristics, management, and outcomes among admissions for primary cardiac tumors: Results from the National Inpatient Sample.

J Card Surg 2021 Jul 27. Epub 2021 Jul 27.

Division of Cardiology, Cardiovascular Research Unit, RWJ Barnabas Health, NBIMC, Newark, New Jersey, USA.

Introduction: Primary cardiac tumors (PCT) are rare, and their contemporary outcomes are not well characterized in the literature. We assessed temporal trends in patient characteristics and management of admissions for PCT in US hospitals.

Methods: Admissions with the principal diagnoses of a PCT (benign neoplasm of heart: ICD-9 212. Read More

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Solution using Stomahesive® wafers for allergic contact dermatitis caused by isobornyl acrylate in glucose monitoring sensors.

Australas J Dermatol 2021 Jul 27. Epub 2021 Jul 27.

Skin Health Institute, Carlton, Victoria, Australia.

Isobornyl acrylate (IBOA) has recently caused a number of cases of allergic contact dermatitis (ACD) from its use in medical devices. We would like to enhance the awareness of this issue with the reporting of three Australian cases, involving two adults and a child. We also report a successful solution by using hydrocolloid wafer (Stomahesive®) as a barrier. Read More

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High Prevalence of DICER1 Mutations and Low Frequency of Gene Fusions in Pediatric Follicular-Patterned Tumors of the Thyroid.

Endocr Pathol 2021 Jul 27. Epub 2021 Jul 27.

College of Medicine, Cancer Research Institute, The Catholic University of Korea, Seoul, 06591, Republic of Korea.

Follicular-patterned tumors of the thyroid in the adult population frequently harbor RAS mutations or PAX8-PPARG rearrangement, but little is known about molecular profiles in the pediatric patients with thyroid tumors, which is rare. To identify the molecular profile of pediatric follicular-patterned tumors, we enrolled 41 pediatric patients with follicular-patterned tumors from two institutions. We did next-generation sequencing using a mutation panel targeting 49 thyroid-tumor-related genes and a fusion panel targeting 88 types of thyroid-related gene fusions. Read More

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Estimating the Public Health and Economic Impact of Introducing the 13-Valent Pneumococcal Conjugate Vaccine or 10-Valent Pneumococcal Conjugate Vaccines into State Immunization Programs in India.

Infect Dis Ther 2021 Jul 27. Epub 2021 Jul 27.

Pfizer Inc., Health Economics and Outcomes Research, New York, USA.

Introduction: Although the pneumococcal conjugate vaccine (PCV) has been introduced into select state immunization programs (SIPs) in India, many children remain unvaccinated. Recently, India's Advisory Committee on Vaccines & Immunization Practices recommended PCV on the pediatric immunization schedule nationally. This study estimates the public health and economic impact of introducing either Pfizer's 13-valent PCV (PCV13-PFE), GlaxoSmithKline's 10-valent PCV (PCV10-GSK), or Serum Institute of India's 10-valent PCV (PCV10-SII) into every pediatric SIP. Read More

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Headache Attributed to Vaccination Against COVID-19 (Coronavirus SARS-CoV-2) with the ChAdOx1 nCoV-19 (AZD1222) Vaccine: A Multicenter Observational Cohort Study.

Pain Ther 2021 Jul 27. Epub 2021 Jul 27.

Kiel Migraine and Headache Centre, Kiel, Germany.

Introduction: The most frequently reported neurological adverse event of ChAdOx1 nCoV-19 (AZD1222) vaccine is headache in 57.5%. Several cases of cerebral venous thrombosis (CVT) have developed after vaccination. Read More

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Bucket-handle meniscal tears in children under the age of 10: a literature review.

Acta Biomed 2021 Jul 26;92(S3):e2021020. Epub 2021 Jul 26.


Background And Aim Of The Work: Traumatic meniscal tears are raising in skeletally immature patients due to increasing participation in sport activities. Nonetheless, meniscal tears remain a rare injury in children, with a lack of evidence regarding treatment and outcome. The aim of the study is to review the literature on BHMT in children aged under 10 years. Read More

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Simultaneous bilateral olecranon fracture: a case report and review of the literature.

Acta Biomed 2021 Jul 26;92(S3):e2021029. Epub 2021 Jul 26.

Orthopaedics and Traumatology Unit, Cattinara Hospital - ASUGI, Strada di Fiume 447, 34149 Trieste (Italy).

Background And Aim Of The Work: A bilateral fracture of the olecranon is a rare injury, with only few cases reported in the literature.

Methods: A single case of bilateral Mayo type II A olecranon fracture in a 88 years old woman is described. A research of all articles regarding simultaneous bilateral olecranon fracture was performed in the PubMed database. Read More

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Cementless reverse total shoulder arthroplasty in a patient affected by Osteogenesis Imperfecta: a case report and review of the literature.

Acta Biomed 2021 Jul 26;92(S3):e2021024. Epub 2021 Jul 26.

Clinica Ortopedica - ASUFC - Udine, Italy DAME - University of Udine, Italy.

Background And Aim Of The Work: Osteogenesis Imperfecta is a rare genetic condition. The use of total shoulder arthroplasty in these patients is very uncommon, with only two cases reported in the literature. This study describes a cementless reverse total shoulder arthroplasty (rTSA) for a multi-fragmented fracture in a patient affected by Osteogenesis Imperfecta (OI) type 1 and aims to review literature results of shoulder replacement in patients affected by this uncommon condition. Read More

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Are vascular grafts at risk of occlusion after total hip replacement? A systematic review of the literature.

Acta Biomed 2021 Jul 26;92(S3):e2021030. Epub 2021 Jul 26.

Clinica Ortopedica - ASUFC - Udine, Italy DAME - University of Udine, Italy.

Vascular complications during and after total hip replacement are relatively uncommon despite the close relationship between the involved structures. Previous surgical procedure of arterial reconstruction or substitution may be at higher risk of damage due to the modification in the anatomical landmarks or to the mechanical properties of the grafts different from native vessels. In literature few cases of graft occlusion or failure are reported during or soon after a total hip replacement. Read More

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Factors influencing the occurrence of infectious disease outbreaks in Lebanon since the Syrian crisis.

Pathog Glob Health 2021 Jul 27:1-9. Epub 2021 Jul 27.

Department of Orthopedic Surgery, Lebanese American University Medical Center, Beirut, Lebanon.

Since the beginning of the Syrian crisis in 2011, the region has witnessed a major population displacement. Lebanon, a country with a population of 4.2 million, has welcomed around one million refugees. Read More

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A Computed Tomography Angiography (CTA): Based score (SGPGI score) to predict level of difficulty, operative, and postoperative outcomes for right-sided radical nephrectomy.

Urologia 2021 Jul 27:3915603211015541. Epub 2021 Jul 27.

Department of Urology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Objective: With the advent of laparoscopic approach for the large (T1b-T3a ± N1) right renal masses, higher rates of complications and conversion to open surgery are being reported. The role of preoperative angioembolization (PAE), which has increased cost and inherent morbidity but may help in select circumstances has also not been clearly defined in the literature. We therefore devised a scoring system (SGPGI score) based on pre-operative Computed Tomography Angiography (CTA) to predict the level of difficulty of radical nephrectomy and enhance its safety and efficacy which could also be used for the judicious use of PAE in selected cases. Read More

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