59,996 results match your criteria report unusual


Case report of metastatic breast cancer mimicking ileal Crohn's disease.

Int J Surg Case Rep 2021 Sep 15;87:106408. Epub 2021 Sep 15.

Department of Clinical Surgical Sciences, The University of the West Indies, St. Augustine, Trinidad and Tobago.

Introduction: Lobular breast cancer (LBC) has an increased risk of gastrointestinal (GI) spread compared with ductal breast carcinoma. Breast cancer commonly metastasises to bone, lung, liver, central nervous system and rarely to the gastrointestinal tract. As the prognosis for breast cancer continues to improve with modern medical practice it is important to be aware of the various clinical presentations and the appropriate management of breast cancer metastases. Read More

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September 2021

Unusual interlayer coupling in layered Cu-based ternary chalcogenides CuMCh (M = Sb, Bi; Ch = S, Se).

Nanoscale 2021 Sep 17;13(35):14621-14627. Epub 2021 Sep 17.

Key Laboratory of Computational Physical Sciences (Ministry of Education), State Key Laboratory of Surface Physics, and Department of Physics, Fudan University, Shanghai 200433, China.

Interlayer interactions play important roles in manipulating the electronic properties of layered semiconductors. One common mechanism is that the valence band maximum (VBM) and the conduction band minimum (CBM) in one layer couple to the VBM and CBM in another layer, respectively, resulting in the decrease of the band gap from the monolayer to the bilayer. Here we report an unusual interlayer coupling mechanism in layered Cu-based ternary chalcogenides CuMCh (M = Sb, Bi; Ch = S, Se) that the CBM in one layer strongly couples to the VBM in the other layer, leading to the band gap increase from the monolayer to the bilayer. Read More

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September 2021

Late Testicular Yolk Sac Tumor With Cerebellar Metastasis and a Rapid Recurrence After a Gross Total Resection: A Case Report.

Cureus 2021 Aug 13;13(8):e17143. Epub 2021 Aug 13.

Department of Neurosurgery, University of Texas Medical Branch, Galveston, USA.

Yolk sac tumor (YST) is the most common prepubertal testicular tumor. It is considered a subtype of non-seminoma germ cell tumor (NSGCT) that is presumed to have an aggressive behavior with high malignant potential, thus requiring multimodality treatment with resection and chemotherapy. Treatment is curative for the majority of patients, even the ones with relapse after a few years. Read More

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Unusual presentation of a five-month-old boy with NaPi2a homozygous mutation without hyperphosphaturia: Case report and review of the literature.

Clin Case Rep 2021 Sep 12;9(9):e04740. Epub 2021 Sep 12.

Department of Pediatrics ZNA Queen Paola Children's Hospital Antwerp Belgium.

Deletions of the gene and mutations in the gene should be considered in patients with atypical presentation, without phosphaturia, with mild hypo to normal phosphatemia, and nephrocalcinosis. Read More

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September 2021

Gonococcus infection probably acquired from bathing in a natural thermal pool: a case report.

J Med Case Rep 2021 Sep 17;15(1):458. Epub 2021 Sep 17.

Department of Biosciences, University of Salzburg, Salzburg, Austria.

Background: Authorities need to recognize that, while rare, gonorrhea can be transmitted nonsexually, and should not be presumed definitive evidence of abuse. We report the unusual case of a girl diagnosed with Neisseria gonorrhoeae after bathing in a heavily frequented hot pool at the edge of the crater lake Specchio di Venere ("Mirror of Venus") on Pantelleria Island, Italy.

Case Presentation: Two days after bathing in the pool, this 11-year-old Austrian girl developed vulvovaginitis that partially settled with antifungal cream. Read More

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September 2021

Pleomorphic Invasive Lobular Cancer of the Breast Presenting with Orbital Metastasis: A Case Report.

Curr Med Imaging 2021 Sep 15. Epub 2021 Sep 15.

Sultan 2. Abdulhamid Han Training and Research Hospital, İstanbul. Turkey.

Background: Orbital metastasis of breast cancer is an unusual condition, especially in the absence of a previous diagnosis of primary breast cancer. The main MRI findings in patients with orbital metastasis are retroorbital soft tissue with thickening of extraocular muscles. Paradoxical enophtalmos secondary to fibrosis can be seen. Read More

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September 2021

Hereditary Pancreatitis in a Young Adult: Acute to Chronic.

Clin Biochem 2021 Sep 13. Epub 2021 Sep 13.

Department of Pathology and ARUP Laboratories, University of Utah, Salt Lake City, Utah, USA. Electronic address:

This case report investigates an unusual case of recurrent pancreatitis. A 22-year-old female was admitted to the emergency room for severe abdominal pain, nausea, and weight loss. She reported having these symptoms since she was a toddler. Read More

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September 2021

Not All Subarachnoid Hemorrhages in Pregnancy Are Intracranial in Origin: A Case Report.

A A Pract 2021 Sep 15;15(9):e01521. Epub 2021 Sep 15.

From the Department of Anesthesiology, University of Maryland School of Medicine, Baltimore, Maryland.

Subarachnoid hemorrhage is uncommon in pregnancy and may be caused by intracranial aneurysms, arteriovenous malformations, venous thrombosis, or preeclampsia. We present an unusual case of subarachnoid hemorrhage in a term parturient where the bleeding originated from an extracranial source, namely a cervicothoracic arteriovenous malformation. This case highlights the challenge of diagnosing this condition when the initial presentation may be nonspecific, lacking in neurologic deficits, and confounded by the simultaneous presence of preeclampsia. Read More

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September 2021

Synthesis of the unusual lipid bis(monoacylglycero)phosphate in environmental bacteria.

Environ Microbiol 2021 Sep 16. Epub 2021 Sep 16.

Microbial Biology, Ruhr University Bochum, Universitätsstraße 150, 44801, Bochum, Germany.

The bacterial membrane is constantly remodelled in response to environmental conditions and the external supply of precursor molecules. Some bacteria are able to acquire exogenous lyso-phospholipids and convert them to the corresponding phospholipids. Here we report that some soil-dwelling bacteria have alternative options to metabolize lyso-phosphatidylglycerol (L-PG). Read More

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September 2021

Models and Processes to Extract Drug-like Molecules From Natural Language Text.

Front Mol Biosci 2021 30;8:636077. Epub 2021 Aug 30.

Department of Computer Science, University of Chicago, Chicago, IL, United States.

Researchers worldwide are seeking to repurpose existing drugs or discover new drugs to counter the disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). A promising source of candidates for such studies is molecules that have been reported in the scientific literature to be drug-like in the context of viral research. However, this literature is too large for human review and features unusual vocabularies for which existing named entity recognition (NER) models are ineffective. Read More

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Moyamoya disease associated with pediatric pulmonary hypertension-a case report.

Cardiovasc Diagn Ther 2021 Aug;11(4):1052-1056

Division of Pediatric Cardiology, Children's Hospital, University of Ulm, Ulm, Germany.

Moyamoya disease (MD) is a rare vaso-occlusive disorder that primarily affects intracranial cerebral arteries. The involvement of extracranial vessels is unusual. However, there are previous reports suggesting MD to be a systemic disorder, causing disease manifestations in vessels of other parts of the body. Read More

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Unusual Presentation of Castleman's Disease Encroaching on the Brachial Plexus.

Cureus 2021 Aug 7;13(8):e16981. Epub 2021 Aug 7.

Department of Medical and Population Health Sciences Research, Florida International University Herbert Wertheim College of Medicine, Miami, USA.

Castleman's disease is an uncommon benign lymphoproliferative disorder that commonly involves the mediastinum. We report an unusual case that involves the presentation of unicentric Castleman's disease in a 52-year-old female. The patient had a supraclavicular mass extending onto the brachial plexus. Read More

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Ruptured intraventricular tuberculous brain abscess mimicking cystic neoplasm: a case report.

Pan Afr Med J 2021 12;39:122. Epub 2021 Jun 12.

Department of Neurosurgery, University Hospital Center Mohammed VI of Marrakech, Marrakech, Morocco.

Central nervous system (CNS) tuberculosis is a potentially life-threatening condition that may manifest in different forms and simulate other pathologies. It rarely involves the ventricles and the occurrence of primary intraventricular tuberculous brain abscess (TBA) has exceptionally been reported. As far as we know, ruptured intraventricular TBA has not been described before. Read More

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An unusual presentation of hydatid cyst: A tight mass a case report with a literature review.

Radiol Case Rep 2021 Nov 8;16(11):3485-3490. Epub 2021 Sep 8.

Radiology department, Mohammed V Military Hospital, Rabat -Morocco.

Hydatidosis is a worldwide infectious disease caused by the larval form of a parasitic tapeworm of helminths affecting mainly the liver and lungs in cattle- and sheep-raising regions. Muscle localization remains extremely rare and its diagnosis is sometimes challenging. We report the case of a 45-year-old man presenting with a swelling of the left thigh gradually increasing in size. Read More

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November 2021

Report of two cases of Accessory Cavitated Uterine Mass (ACUM): Diagnostic challenge for MRI.

Radiol Case Rep 2021 Nov 7;16(11):3465-3469. Epub 2021 Sep 7.

Department of Radiology B, Strasbourg University Hospital - New Civil Hospital, Strasbourg, 67091 Cedex, France.

Cystic adenomyosis is an unusual form of adenomyosis, characterized by a well-circumscribed cavitated endometrial gland and stroma, ≥ 1 cm in diameter, located within the myometrium. Few cases have been reported in the gynecological literature, with confusing naming such as: juvenile cystic adenomyosis, cystic myometrial lesions, cystic adenomyoma or juvenile adenomyotic cysts. The current preferred terminology is accessory cavitated uterine mass /or malformation (ACUM). Read More

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November 2021

Asymptomatic unilateral aplasia of the left parotid gland: an unusual entity and case report.

Radiol Case Rep 2021 Nov 6;16(11):3453-3456. Epub 2021 Sep 6.

Radiology Department, University Hospital of Larissa, Larissa, Greece.

Congenital agenesis of major salivary glands is considered a very infrequent condition and typically appears to be a coincidental finding. It can be present as sporadic case or may be combined with aplasia or hypoplasia of other salivary glands or the lacrimal glands, or as a part of syndromes. Only 23 cases documented in the literature to date, while the youngest patient was 50 days old. Read More

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November 2021

Hematuria - Look beyond the Urinary Tract - A Rare Case Report.

J Midlife Health 2021 Apr-Jun;12(2):176-178. Epub 2021 Jul 27.

Department of Medicine, Lady Hardinge Medical College and SSK Hospital, New Delhi, India.

The major causes of hematuria in a middle-aged female include infections, renal calculi, or structural abnormalities of the urinary tract. Most patients are investigated and treated on an outpatient basis. While a possibility of malignancy of the bladder or kidneys may also be considered, hematological malignancy is an uncommon cause of hematuria. Read More

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Evidence of two-dimensional flat band at the surface of antiferromagnetic kagome metal FeSn.

Nat Commun 2021 Sep 15;12(1):5345. Epub 2021 Sep 15.

Department of Physics, Massachusetts Institute of Technology, Cambridge, MA, USA.

The kagome lattice has long been regarded as a theoretical framework that connects lattice geometry to unusual singularities in electronic structure. Transition metal kagome compounds have been recently identified as a promising material platform to investigate the long-sought electronic flat band. Here we report the signature of a two-dimensional flat band at the surface of antiferromagnetic kagome metal FeSn by means of planar tunneling spectroscopy. Read More

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September 2021

ADAR1 edits the SenZ and SenZ-ability of RNA.

Immunity 2021 Sep;54(9):1909-1911

Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, 53127 Bonn, Germany; Unit of Experimental Immunology, Department of Biomedical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium. Electronic address:

Some RNAs can assume a Z conformation, an unusual, left-handed turn. In this issue of Immunity, three studies report that mutations in the Zα-RNA binding domain of the adenosine deaminase ADAR1 are sufficient to induce autoinflammatory disease in mice, which models human Aicardí-Goutières syndrome, highlighting the important role of Z-RNA editing in limiting innate immune recognition of endogenous RNA. Read More

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September 2021

Occurrence of Klinefelter Syndrome Mosaic 45,X/46,XY/47,XXY/48,XXYY/48,XXXY and Primary Hyperparathyroidism.

AACE Clin Case Rep 2021 Sep-Oct;7(5):293-298. Epub 2021 Mar 13.

Department of Genetics, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.

Objective: The presence of primary hyperparathyroidism (PHPT) and Klinefelter syndrome (KS) is rare, and its association with KS mosaicism is even rarer. We report an unusual combination of these entities with a mild phenotype of KS.

Methods: The patient was a 44-year-old male with a history of PHPT who had recurrent urolithiasis despite being treated with a successful parathyroidectomy. Read More

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Minimally Invasive Endoscopic Approach towards Management of Frontoethmoidal Mucocoele with Lateral Displacement of Eyeball and Proptosis - A Case Report.

Ann Maxillofac Surg 2021 Jan-Jun;11(1):129-131. Epub 2021 Jul 24.

Department of Oral & Maxillofacial Surgery, Kaushal Dental Care Centre, New Delhi, India.

Rationale: Mucocoeles of paranasal sinuses are expansile and destructive lesions which can present with a variety of symptoms. If not treated early, they may lead to various complications.

Patient Concerns: This report presents a case of a 26-year-old male patient with complaints of swelling of the left eye and double vision for 18 months. Read More

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Left hand necrosis as the initial presentation of disseminated mucormycosis: A case report and literature review.

IDCases 2021 31;26:e01269. Epub 2021 Aug 31.

Parkland Health and Hospital Systems, Dallas, TX, USA.

Cutaneous mucormycosis typically occurs as a primary infection following traumatic inoculation or as a secondary disseminated disease in immunocompromised patients with hematologic malignancy or organ transplantation. We describe an unusual case of a poorly controlled type 1 diabetic patient presenting with wet gangrene of the hand due to angioinvasive dissemination from a primary pulmonary infection, with additional suspected foci of cardiac and central nervous system involvement. Despite combined medical and surgical treatment, the patient ultimately died due to complications of her infection. Read More

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Unusual case of immune haemolytic disease causing severe neonatal cholestasis in a newborn.

BMJ Case Rep 2021 Sep 14;14(9). Epub 2021 Sep 14.

Neonatology, Bharati Vidyapeeth University, Pune, Maharashtra, India.

Neonatal hyperbilirubinaemia is a very common entity witnessed in most of the newborns. Rarely are there events where the bilirubin levels reach extreme values mandating invasive therapy. Unconjugated hyperbilirubinaemia when solely present is easy to manage and diagnose the common aetiological factors associated with it. Read More

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September 2021

Multiple, large intra-abdominal cystic lesions and iron deficiency anaemia as the presenting symptoms of SDHD gastrointestinal stromal tumour (GIST) in a young sub-Saharan woman.

BMJ Case Rep 2021 Sep 14;14(9). Epub 2021 Sep 14.

Anatomical Pathology, Butaro Hospital, Burera, Rwanda.

We report the case of a 27-year-old female patient from sub-Saharan Africa who presented with non-specific abdominal complaints, iron deficiency anaemia and multiple, large intra-abdominal cystic lesions on imaging. The lesions appeared to be a most unusual presentation of gastrointestinal stromal tumour (GIST). GIST is a sarcomatous tumour that comprises only 0. Read More

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September 2021

An Unusual Cause of Bulbar Palsy in the Emergency Department.

J Emerg Med 2021 Sep 11. Epub 2021 Sep 11.

Department of Emergency Medicine, Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry, India. Electronic address:

Background: Osmotic demyelination syndrome commonly occurs after rapid correction of hyponatremia. But it has also been reported after graded correction of hyponatremia in the presence of other risk factors like chronic alcoholism, malnutrition, liver disease, and hypokalemia.

Case Report: We report a case of a 67-year-old man who presented with dysphagia and nasal regurgitation and had features suggestive of bulbar palsy on neurological examination. Read More

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September 2021

A Rare Case of Henoch-Schönlein Purpura Following a COVID-19 Vaccine-Case Report.

SN Compr Clin Med 2021 Sep 8:1-4. Epub 2021 Sep 8.

Department of Emergency, Cheikh Khalifa International University Hospital, Mohammed VI University of Health Sciences (UM6SS), Casablanca, Morocco.

In the COVID-19 pandemic era, anti-SARS-CoV-2 vaccination is considered to be the most efficient way to overtake the COVID-19 scourge. Like all medicines, vaccines are not devoid of risks and can in rare cases cause some various side effects. The objective of this case report is to highlight this unusual presentation of Henoch-Schönlein purpura following an anti-COVID-19 vaccination in a 62-year-old adult. Read More

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September 2021

Multimodality Imaging in COVID19 Patient with Large Mobile RV Thrombus Protruding into the Pulmonary Trunk with Bilateral Pulmonary Embolism.

J Cardiol Cases 2021 Sep 9. Epub 2021 Sep 9.

Division of Nuclear Medicine, Section of Cardiac Hybrid Imaging, Victoria Hospital, London Health Sciences Centre, London, Ontario, Canada.

Inflammation related to coronavirus disease (COVID)-19 can promote a pro-thrombotic process and subsequent thrombosis. We report a confirmed COVID-19 case in a 51-year-old patient who presented with chest pain and severe hypoxemia. Although the right heart chambers are unusual locations for a thrombus, an echocardiogram demonstrated a large mobile right ventricular thrombus protruding into the right ventricle outflow tract. Read More

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September 2021

Superconducting Long-Range Proximity Effect through the Atomically Flat Interface of a BiTe Topological Insulator.

J Phys Chem Lett 2021 Sep 13:9068-9075. Epub 2021 Sep 13.

Laboratoire de Physique et d'Etudes des Matériaux, LPEM, UMR-8213, ESPCI Paris, PSL Research University, CNRS, Sorbonne University, 75005 Paris, France.

We report on structural and electronic properties of superconducting nanohybrids made of Pb grown in the ultrahigh vacuum on the atomically clean surface of single crystals of topological BiTe. In situ scanning tunneling microscopy and spectroscopy demonstrated that the resulting network is composed of Pb-nanoislands dispersed on the surface and linked together by an amorphous atomic layer of Pb, which wets BiTe. As a result, the superconducting state of the system is characterized by a thickness-dependent superconducting gap of Pb-islands and by a very unusual position-independent proximity gap between them. Read More

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September 2021

A case of colonoscopy-induced Wunderlich's syndrome in a hemodialysis patient: coincidence or association?

J Bras Nefrol 2021 Sep 13. Epub 2021 Sep 13.

Notre Dame Maritime Hospital, Department of Urology, Byblos, Lebanon.

Wunderlich syndrome, or spontaneous renal hemorrhage (SRH), is a rare condition encountered in patients undergoing chronic hemodialysis (HD) usually attributed to acquired cystic kidney disease (ACKD) among other causes. In the literature, colonoscopy is associated with splenic injuries, and renal hemorrhage has not been previously described. Management can range from conservative treatment to angiographic embolization or exploration and nephrectomy. Read More

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September 2021

Complex Fibroadenoma with Pronounced Squamous Metaplasia: A Rare Case Report, Differential Diagnostic Considerations, and Associated Breast Cancer Risk.

Int J Surg Pathol 2021 Sep 13:10668969211035842. Epub 2021 Sep 13.

12280Wake Forest University Baptist Medical Center, Winston-Salem, NC, USA.

Squamous metaplasia of the breast is a rare and unusual finding. A number of benign and malignant differential entities exist when squamous cells are present in a breast lesion. Our patient was found to have pronounced squamous metaplasia and keratin cysts arising in a complex fibroadenoma. Read More

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September 2021