130 results match your criteria reorganized considered


Epidemiology of tick-borne encephalitis in Poland (2010-2019) and the impact of the COVID-19 pandemic on the notified incidence of the disease.

Przegl Epidemiol 2021 ;75(1):76-85

Medical University of Bialystok, Department of Infectious Diseases and Neuroinfections.

Introduction: Tick-borne encephalitis (TBE) is endemic in many parts of Eurasia including countries previously considered to be free from the disease. The incidence of TBE is changing owing to various ecological and climatic factors. The factors influencing the variability of the number of TBE cases are still under investigation. Read More

View Article and Full-Text PDF
January 2021

Graduate student confidence following a for-credit systematic review course pilot.

J Med Libr Assoc 2021 Apr;109(2):323-329

Purdue University, West Lafayette, IN.

Background: In 2015, librarians at Purdue University began fielding requests from many disciplines to consult or collaborate on systematic review projects, and in 2016, health sciences librarians led the launch of a formal systematic review service. In 2019, Purdue University Libraries was reorganized as the Libraries and School of Information Studies (PULSIS) and assigned its own course designation, ILS. The increase in calls for systematic review services and the ability to teach ILS courses inspired the development of a credit-bearing ILS systematic review course. Read More

View Article and Full-Text PDF

Functional reorganization of brain regions into a network in childhood absence epilepsy: A magnetoencephalography study.

Epilepsy Behav 2021 Jul 8;122:108117. Epub 2021 Jul 8.

Department of Neurology, The Affiliated Brain Hospital of Nanjing Medical University, Nanjing Medical University, Nanjing, Jiangsu 210029, China. Electronic address:

Objective: Epilepsy is considered as a network disorder. However, it is unknown how normal brain activity develops into the highly synchronized discharging activity seen in disordered networks. This study aimed to explore the epilepsy brain network and the significant re-combined brain areas in childhood absence epilepsy (CAE). Read More

View Article and Full-Text PDF

[Impact of family restrictions during COVID-19 pandemic on the use of physical restraint in an acute hospital: An observational study].

J Healthc Qual Res 2021 May 18. Epub 2021 May 18.

Área de Desarrollo de Enfermería, Hospital Universitari Mútua Terrassa, Terrassa, Barcelona, España.

Introduction: During the worldwide pandemic of COVID-19 caused by coronavirus SARS-CoV-2, hospitals developed contingency plans that transformed and reorganized the hospital activity. One of the measures was to restrict access to family members of hospitalized patients. The presence of the patient's family is considered an alternative to physical restraint. Read More

View Article and Full-Text PDF

Psychometric Testing of the Self-care of Hypertension Inventory Version 3.0.

J Cardiovasc Nurs 2021 Jun 9. Epub 2021 Jun 9.

Victoria Vaughan Dickson, PhD, RN, CRNP, FAHA, FHFSA, FAAN Associate Professor, New York University Rory Meyers College of Nursing. Jason Fletcher, PhD Senior Biostatistician, New York University Rory Meyers College of Nursing. Barbara Riegel, PhD, RN, FAHA, FHFSA, FAAN Edith Clemmer Steinbright Professor of Gerontology, University of Pennsylvania School of Nursing, Philadelphia and Professorial Fellow, Australian Catholic University.

In this updated Self-care of Hypertension Inventory Version 3.0 (SC-HI v3.0), items were added to better reflect the Theory of Self-care of Chronic Illness and revised based on recent research. Read More

View Article and Full-Text PDF

Response to a massive SARS-CoV-2 infection in a nursing home transformed into a caring center.

Aging Clin Exp Res 2021 Feb 28;33(2):443-450. Epub 2021 Jan 28.

Senior Researcher, University of Padua, Padua, Italy.

Background: The best policy to follow when nursing homes are massively hit by SARS-CoV2 is unclear.

Aim: To describe COVID-19 containment in a nursing home transformed into a caring center.

Methods: Physicians and nurses were recruited. Read More

View Article and Full-Text PDF
February 2021

Additional Role of Nicotinic Acid Hydroxylase for the Transformation of 3-Succinoyl-Pyridine by sp. Strain JY-Q.

Appl Environ Microbiol 2021 02 26;87(6). Epub 2021 Feb 26.

College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou, China

Nicotine and nicotinic acid (NA) are both considered to be representatives of -heterocyclic aromatic compounds, and their degradation pathways have been revealed in species. However, the cooccurrence of these two pathways has only been observed in sp. strain JY-Q. Read More

View Article and Full-Text PDF
February 2021

In vivo imaging of neural circuit formation in the neonatal mouse barrel cortex.

Authors:
Takuji Iwasato

Dev Growth Differ 2020 Oct 26;62(7-8):476-486. Epub 2020 Oct 26.

Laboratory of Mammalian Neural Circuits, National Institute of Genetics, Mishima, Japan.

Higher brain function in mammals primarily relies on complex yet sophisticated neuronal circuits in the neocortex. In early developmental stages, neocortical circuits are coarse. Mostly postnatally, the circuits are reorganized to establish mature precise connectivity, in an activity-dependent manner. Read More

View Article and Full-Text PDF
October 2020

Sensitive immunoassay of cardiac troponin I using an optimized microelectrode array in a novel integrated microfluidic electrochemical device.

Anal Bioanal Chem 2020 Dec 4;412(30):8325-8338. Epub 2020 Oct 4.

Key Laboratory for Micro/Nano Technology and System of Liaoning Province, Dalian University of Technology, No.2 Linggong Road, Ganjingzi District, Dalian, 116024, Liaoning, China.

A sensitive and portable microfluidic electrochemical array device (μFED) was developed for the immunoassay of trace amounts of human cardiac troponin I (cTnI), which is an attractive biomarker for acute myocardial infarction (AMI). The classical "sandwich" method was adopted for the immunoassay. The capture antibody was immobilized using a self-assembled monolayer (SAM) technique, and the process was reorganized to be compatible with the bonding process. Read More

View Article and Full-Text PDF
December 2020

Atypical language representation as a protective factor against verbal memory decline following epilepsy surgery.

Epilepsy Behav 2020 11 18;112:107451. Epub 2020 Sep 18.

Barrow Neurological Institute, United States of America. Electronic address:

Objective: An important role of neuropsychology in the preoperative evaluation of epilepsy surgery candidates is to assess risk for postoperative memory decline. One factor associated with postoperative verbal memory decline is surgery in the language-dominant temporal lobe (TL). The aim of the study was to determine whether atypical language representation has a protective effect against verbal memory decline following left temporal, frontotemporal, or hippocampal excision. Read More

View Article and Full-Text PDF
November 2020

Emerging challenges and possible strategies in maxillo-facial and oral surgery during the COVID-19 pandemic.

J Oral Sci 2020 Sep 24;62(4):452-454. Epub 2020 Aug 24.

Cranio-Maxillo-Facial Unit and Biomaterials Laboratory, Department of Medical and Surgical Sciences for Children & Adults, University of Modena and Reggio Emilia.

The Coronavirus disease 2019 (COVID-19) pandemic suddenly took the world by storm and Italy was one of the hardest hit countries. Maxillo-facial surgery and dentistry procedures had to be significantly reorganized, since they are considered high-risk procedures. Protocols had to be changed and interdepartmental cooperation was put in place to plan surgical interventions and maintain high standards. Read More

View Article and Full-Text PDF
September 2020

BRCA testing in a genomic diagnostics referral center during the COVID-19 pandemic.

Mol Biol Rep 2020 Jun 9;47(6):4857-4860. Epub 2020 May 9.

Molecular and Genomic Diagnostics Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy.

The first person-to-person transmission of the 2019-novel coronavirus in Italy on 21 February 2020 led to an infection chain that represents one of the largest known COVID-19 outbreaks outside Asia. Hospitals have been forced to reorganized their units in response to prepare for an unforeseen healthcare emergency. In this context, our laboratory (Molecular and Genomic Diagnostics Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS) re-modulated its priorities by temporarily interrupting most of the molecular tests guaranteeing only those considered "urgent" and not postponable. Read More

View Article and Full-Text PDF

The Combination of Antimicrobial Photodynamic Therapy and Photobiomodulation Therapy for the Treatment of Palatal Ulcers: A Case Report.

J Lasers Med Sci 2020 15;11(2):228-233. Epub 2020 Mar 15.

Department of Pediatric Dentistry and Orthodontics, Federal University of Minas Gerais - UFMG, Belo Horizonte - MG, Brazil.

One of the unexpected side effects of the Haas type palatal expander is ulcers progressing to necrotic lesions in the palatal area due to poor hygiene. The use of antibiotic therapy is mandatory. However, long periods of healing/pain and the need for a systemic host response with the aid of metabolization, especially in children, are issues that should be taken into account in the management of this type of injury. Read More

View Article and Full-Text PDF

Language Dominance in Patients With Malformations of Cortical Development and Epilepsy.

Front Neurol 2019 21;10:1209. Epub 2019 Nov 21.

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Language function may be reorganized in patients with malformations of cortical development (MCD). This prospective cohort study aimed in assessing language dominance in a large group of patients with MCD and epilepsy using functional MRI (fMRI). Sixty-eight patients (40 women) aged 10-73 years (median, 28. Read More

View Article and Full-Text PDF
November 2019

Quantification of the dynamic behaviour of ribosomal DNA genes and nucleolus during yeast Saccharomyces cerevisiae cell cycle.

J Struct Biol 2019 11 23;208(2):152-164. Epub 2019 Aug 23.

Laboratoire de Biologie Moléculaire Eucaryote, Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, UPS, 31000 Toulouse, France. Electronic address:

Spatial organisation of chromosomes is a determinant of genome stability and is required for proper mitotic segregation. However, visualization of individual chromatids in living cells and quantification of their geometry, remains technically challenging. Here, we used live cell imaging to quantitate the three-dimensional conformation of yeast Saccharomyces cerevisiae ribosomal DNA (rDNA). Read More

View Article and Full-Text PDF
November 2019

Observations of Membrane Domain Reorganization in Mechanically Compressed Artificial Cells.

Chembiochem 2019 10 1;20(20):2666-2673. Epub 2019 Oct 1.

ETH Zurich, Department of Biosystems Science and Engineering, Mattenstrasse 26, 4058, Basel, Switzerland.

Giant unilamellar vesicles (GUVs) are considered to be the gold standard for assembling artificial cells from the bottom up. In this study, we investigated the behavior of such biomimetic vesicles as they were subjected to mechanical compression. A microfluidic device is presented that comprises a trap to capture GUVs and a microstamp that is deflected downwards to mechanically compress the trapped vesicle. Read More

View Article and Full-Text PDF
October 2019

Value of Texture Analysis of Intravoxel Incoherent Motion Parameters in Differential Diagnosis of Pancreatic Neuroendocrine Tumor and Pancreatic Adenocarcinoma.

Chin Med Sci J 2019 Mar;34(1):1-9

Department of Radiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572013, China.

Objective To evaluate the value of texture features derived from intravoxel incoherent motion (IVIM) parameters for differentiating pancreatic neuroendocrine tumor (pNET) from pancreatic adenocarcinoma (PAC).Methods Eighteen patients with pNET and 32 patients with PAC were retrospectively enrolled in this study. All patients underwent diffusion-weighted imaging with 10 b values used (from 0 to 800 s/mm ). Read More

View Article and Full-Text PDF

Re-examining the crowding hypothesis in pediatric epilepsy.

Epilepsy Behav 2019 05 20;94:281-287. Epub 2019 Mar 20.

Department of Psychology, The Hospital for Sick Children, 555 University Ave, Toronto, ON M5G 1X8, Canada; Department of Psychology, University of Toronto Mississauga, Mississauga, Canada; Neurosciences and Mental Health Program, The Hospital for Sick Children, Toronto, Canada. Electronic address:

Objective: In adults with left-sided epilepsy, reorganized language may "crowd out" right-hemisphere visual-spatial skills, with relative sparing of language (i.e., the crowding hypothesis). Read More

View Article and Full-Text PDF

Is play a behavior system, and, if so, what kind?

Behav Processes 2019 Mar 14;160:1-9. Epub 2019 Jan 14.

Department of Psychology, University of Lethbridge, Lethbridge, Alberta, Canada.

Given that many behavior patterns cluster together in sequences that are organized to solve specific problems (e.g., foraging), a fruitful perspective within which to study behaviors is as distinct 'behavior systems'. Read More

View Article and Full-Text PDF

Mechanisms of Creativity Differences Between Art and Non-art Majors: A Voxel-Based Morphometry Study.

Front Psychol 2018 11;9:2319. Epub 2018 Dec 11.

School of Sports and Health of East China Normal University, Shanghai, China.

Creativity is considered the ability to generate new ideas or behaviors, an ability that have diverse expressions in different human groups, such as painters and non-painters. Art major students require more creative activities than non-art students do. In this study, we plan to explore the figural creativity abilities of art major students and whether these students exhibited higher figural creativity scores and why their brain structure of gray matter are lower which may benefit from their professional training relative to non-art majors. Read More

View Article and Full-Text PDF
December 2018

The role of mesenchymal-epithelial transition in endometrial function.

Hum Reprod Update 2019 01;25(1):114-133

Department of Obstetrics, Gynecology, and Women's Health, Rutgers-New Jersey Medical School, Newark, NJ, USA.

Background: The human uterine endometrium undergoes significant remodeling and regeneration on a rapid and repeated basis, after parturition, menstruation, and in some cases, injury. The ability of the adult endometrium to undergo cyclic regeneration and differentiation/decidualization is essential for successful human reproduction. Multiple key physiologic functions of the endometrium require the cells of this tissue to transition between mesenchymal and epithelial phenotypes, processes known as mesenchymal-epithelial transition (MET) and epithelial-mesenchymal transition (EMT). Read More

View Article and Full-Text PDF
January 2019

Organization of projection from brainstem auditory nuclei to the inferior colliculus of Japanese house bat (Pipistrellus abramus).

Brain Behav 2018 08 12;8(8):e01059. Epub 2018 Jul 12.

Neuroethology and Bioengineering Laboratory, Faculty of Life and Medical Sciences, Doshisha University, Kyotanabe, Japan.

Objectives: Echolocating bats show remarkable specialization which is related to analysis of echoes of biosonars in subcortical auditory brainstem pathways. The inferior colliculus (IC) receives inputs from all lower brainstem auditory nuclei, i.e. Read More

View Article and Full-Text PDF

Coherent apoptotic and autophagic activities involved in regression of chicken postovulatory follicles.

Aging (Albany NY) 2018 04;10(4):819-832

Department of Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou, Zhejiang Province 310058, China.

After ovulation in mammals, rupture of mature follicles is reorganized into the corpus luteum that secrets progesterone (P) to stimulate endometrial development. The situation in birds differs considerably. Beyond ovulation the ruptured avian follicle forms a postovulatory follicle (POF) that is not considered analogous to mammalian corpus luteum. Read More

View Article and Full-Text PDF

Recent advances in polysaccharides from Ophiopogon japonicus and Liriope spicata var. prolifera.

Int J Biol Macromol 2018 Jul 7;114:1257-1266. Epub 2018 Apr 7.

Chongqing Jiangbei Hospital of Traditional Chinese Medicine, Chongqing 400020, PR China.

O. japonicus and L. spicata var. Read More

View Article and Full-Text PDF

Fast Screening Technology for Drug Emergency Management: Predicting Suspicious SNPs for ADR with Information Theory-based Models.

Comb Chem High Throughput Screen 2018 ;21(2):93-99

Second School of Clinic Medicine, Guangzhou University of Chinese Medicine, Guanzhou 510120, China.

Objective: The genetic polymorphism of Cytochrome P450 (CYP 450) is considered as one of the main causes for adverse drug reactions (ADRs). In order to explore the latent correlations between ADRs and potentially corresponding single-nucleotide polymorphism (SNPs) in CYP450, three algorithms based on information theory are used as the main method to predict the possible relation.

Methods: The study uses a retrospective case-control study to explore the potential relation of ADRs to specific genomic locations and single-nucleotide polymorphism (SNP). Read More

View Article and Full-Text PDF

Dynamic Reorganization of the Cytoskeleton during Apoptosis: The Two Coffins Hypothesis.

Int J Mol Sci 2017 Nov 11;18(11). Epub 2017 Nov 11.

Centro Andaluz de Biología del Desarrollo (CABD), and Centro de Investigación Biomédica en Red: Enfermedades Raras, Instituto de Salud Carlos III, Consejo Superior de Investigaciones Científicas, Universidad Pablo de, Carretera de Utrera Km 1, 41013 Sevilla, Spain.

During apoptosis, cells undergo characteristic morphological changes in which the cytoskeleton plays an active role. The cytoskeleton rearrangements have been mainly attributed to actinomyosin ring contraction, while microtubule and intermediate filaments are depolymerized at early stages of apoptosis. However, recent results have shown that microtubules are reorganized during the execution phase of apoptosis forming an apoptotic microtubule network (AMN). Read More

View Article and Full-Text PDF
November 2017

: A New Strategy for Vaccination.

Avicenna J Med Biotechnol 2017 Oct-Dec;9(4):163-168

Department of Microbiology, Islamic Azad University, Arak Branch, Arak, Iran.

Needle free vaccines have a several advantages and very attractive way for vaccination. In a body, mucosal surfaces provide a universal entry portal for all the known and emerging infectious pathogenic microbes. Therefore, it seems, vaccination strategies need to be reorganized for vaccines that are hindering the entry capability of pathogenic microbes through mucosal surfaces. Read More

View Article and Full-Text PDF
November 2017

Theoretical modeling of mechanical homeostasis of a mammalian cell under gravity-directed vector.

Biomech Model Mechanobiol 2018 02 17;17(1):191-203. Epub 2017 Aug 17.

Center for Biomechanics and Bioengineering, Key Laboratory of Microgravity (National Microgravity Laboratory), and Beijing Key Laboratory of Engineered Construction and Mechanobiology, Institute of Mechanics, Chinese Academy of Sciences, Beijing, China.

Translocation of dense nucleus along gravity vector initiates mechanical remodeling of a eukaryotic cell. In our previous experiments, we quantified the impact of gravity vector on cell remodeling by placing an MC3T3-E1 cell onto upward (U)-, downward (D)-, or edge-on (E)- orientated substrate. Our experimental data demonstrate that orientation dependence of nucleus longitudinal translocation is positively correlated with cytoskeletal (CSK) remodeling of their expressions and structures and also is associated with rearrangement of focal adhesion complex (FAC). Read More

View Article and Full-Text PDF
February 2018

The Molecular Revolution in Cutaneous Biology: Chromosomal Territories, Higher-Order Chromatin Remodeling, and the Control of Gene Expression in Keratinocytes.

J Invest Dermatol 2017 05;137(5):e93-e99

Centre for Skin Sciences, Faculty of Life Sciences, University of Bradford, Bradford, UK; Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts, USA. Electronic address:

Three-dimensional organization of transcription in the nucleus and mechanisms controlling the global chromatin folding, including spatial interactions between the genes, noncoding genome elements, and epigenetic and transcription machinery, are essential for establishing lineage-specific gene expression programs during cell differentiation. Spatial chromatin interactions in the nucleus involving gene promoters and distal regulatory elements are currently considered major forces that drive cell differentiation and genome evolution in general, and such interactions are substantially reorganized during many pathological conditions. During terminal differentiation of the epidermal keratinocytes, the nucleus undergoes programmed transformation from highly active status, associated with execution of the genetic program of epidermal barrier formation, to a fully inactive condition and finally becomes a part of the keratinized cells of the cornified epidermal layer. Read More

View Article and Full-Text PDF

Quality of Life Changes Following Concurrent Septoplasty and/or Inferior Turbinoplasty During Endoscopic Pituitary Surgery.

World Neurosurg 2017 Feb 9;98:303-307. Epub 2016 Nov 9.

Division of Otolaryngology/Head and Neck Surgery, Department of Surgery, Albany Medical Center, Albany, New York, USA. Electronic address:

Objective: Endoscopic endonasal transsphenoidal surgery (EETS) is a widely accepted technique for sellar tumors. Common findings during preoperative assessment include septal deviations and turbinate hypertrophy. This study evaluated quality of life changes after concurrent septoplasty and/or inferior turbinoplasty during EETS. Read More

View Article and Full-Text PDF
February 2017