Sci Rep 2021 Apr 16;11(1):8356. Epub 2021 Apr 16.
Penn Neurodegeneration Genomics Center, Perelman School of Medicine, University of Pennsylvania, Richards Building, D101, 3700 Hamilton Walk, Philadelphia, PA, 19104, USA.
While awaiting the COVID-19 vaccines, researchers have been actively exploring the effectiveness of existing vaccines against the new virus, among which the BCG vaccine (Bacillus Calmette-Guérin) receives the most attention. While many reports suggest a potential role for BCG immunization in ameliorating SARS-CoV-2 infection, these findings remain controversial. With country-level COVID-19 outbreak data from Johns Hopkins University Coronavirus Resource Center, and BCG program data from World Atlas of BCG Policies and Practices and WHO/UNICE, we estimated a dynamic model to investigate the effect of BCG vaccination across time during the pandemic. Read More