Sci Total Environ 2021 Mar 10;778:146257. Epub 2021 Mar 10.
Royal Academy of Veterinary Sciences of Spain (RACVE), Maestro Ripoll, 8, 28006 Madrid, Spain; Department of Pharmacology and Toxicology, Faculty of Veterinary Medicine, Universidad Complutense de Madrid (UCM) and Research Institute Hospital 12 de Octubre (i+12), 28040 Madrid, Spain.
Several medicinal products for human use are currently under consideration as potential treatment for COVID-19 pandemic. As proposals cover also prophylactic use, the treatment could be massive, resulting in unprecedent levels of antiviral emissions to the aquatic environment. We have adapted previous models and used available information for predicting the environmental impact of representative medicinal products, covering the main groups under consideration: multitarget antiparasitic (chloroquines and ivermectin), glucocorticoids, macrolide antibiotics and antiviral drugs including their pharmacokinetic boosters. Read More