Cancer Chemother Pharmacol 2021 Jul 13. Epub 2021 Jul 13.
Department of Gastroenterology, Renmin Hospital, Hubei University of Medicine, Maojian District, Chaoyangzhong Road 39, Shiyan, 442000, Hubei, China.
Background: Cytosolic phospholipase A2alpha (cPLA2α), an enzyme that is responsible for the hydrolysis of membrane phospholipids, is a key mediator of tumor transformation, progression and metastasis. The role of cPLA2α in gastric cancer has not been revealed.
Methods: cPLA2α expression was analyzed using RT-PCR and immunohistochemistry approaches in gastric cancer patient samples (n = 26) and multiple cell lines (n = 7). Read More