92 results match your criteria regression p=052

Associations between Bone Material Strength Index, Calcaneal Quantitative Ultrasound, and Bone Mineral Density in Men.

J Endocr Soc 2021 Apr 22;5(4):bvaa179. Epub 2020 Nov 22.

Deakin University, IMPACT - Institute for Mental and Physical Health and Clinical Translation, Geelong, VIC, Australia.

Objectives: Impact micro-indentation (IMI) measures bone material strength index (BMSi) in vivo. This study investigated how IMI is associated with calcaneal quantitative ultrasound and bone densitometry parameters in men.

Methods: BMSi was measured on the tibial plateau using the OsteoProbe in 377 men (age 33-96 years) from the Geelong Osteoporosis Study. Read More

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Predictors of recantation after child sexual abuse disclosure among a Brazilian sample.

Child Abuse Negl 2021 May 10;115:105006. Epub 2021 Mar 10.

Federal University of Rio Grande do Sul, Brazil.

Background: Recantation after child sexual abuse (CSA) disclosure refers to the complete denial of prior reports by a victim. In substantiated cases of CSA, recantation has negative effects on criminal proceedings and the protection of current and future victims. Past studies have identified the socio-family factors and CSA characteristics that are associated with recantation. Read More

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Relationship Between Gene Polymorphism of Methylenetetrahydrofolate Reductase C677T and Left Ventricular Hypertrophy in Chinese Patients with Chronic Kidney Disease.

Lab Med 2021 Mar 8. Epub 2021 Mar 8.

Department of Nephrology, Zhongshan Hospital, Fudan University, Shanghai, China.

Objective: This study aimed to investigate the relationship between the gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) C677T and left ventricular hypertrophy (LVH) in patients with chronic kidney disease (CKD).

Methods: A total of 763 Chinese patients with CKD undergoing genetic testing were included in the study. The association between the gene polymorphism of MTHFR C677T and echocardiographic parameters was analyzed through univariate and multivariate analyses. Read More

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Transepithelial corneal collagen cross-linking using iontophoresis versus the Dresden protocol in progressive keratoconus: A meta-analysis.

Clin Exp Ophthalmol 2021 Mar 5. Epub 2021 Mar 5.

Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

Background: Standard epithelium-off collagen cross-linking using Dresden protocol (S-CXL) is the standard of care for progressive keratoconus. Despite its efficacy, epithelial debridement is associated with pain, delayed visual rehabilitation, stromal oedema and haze. Minimising these complications while achieving a comparable efficacy remains an unmet need. Read More

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Impact of donor blood type on outcomes after prolonged allograft ischemic times.

J Thorac Cardiovasc Surg 2021 Jan 12. Epub 2021 Jan 12.

Department of Cardiac Surgery, University of Michigan Frankel Cardiovascular Center, Ann Arbor, Mich.

Objective: The study objective was to determine the influence of allograft ischemic time on heart transplant outcomes among ABO donor organ types given limited prior reports of its survival impact.

Methods: We identified 32,454 heart transplants (2000-2016) from the United Network for Organ Sharing database. Continuous and categoric variables were analyzed by parametric and nonparametric testing. Read More

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January 2021

The risks of ankylosis of 89 avulsed human teeth stored in saliva prior to replantation-A re-evaluation of a long-term clinical study.

Dent Traumatol 2021 Feb 1. Epub 2021 Feb 1.

Department of Oral and Maxillofacial Surgery and Medicine, Faculty of Odontology, Malmö University, Malmö, Sweden.

Background/aim: The survival of an avulsed tooth highly depends on the emergency management. The aim of this study was to evaluate the risk of ankylosis for avulsed human teeth stored in saliva preceded by various dry storage conditions prior to replantation.

Material And Methods: Data include 74 patients (54 male and 20 female) with 89 avulsed and replanted teeth (16 immature teeth, 73 mature teeth). Read More

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February 2021

Prevalence and Factors Associated With Liver Fibrosis Among Adult HIV-Infected Patients Attending Urban and Rural Care Clinics in Uganda.

Open Forum Infect Dis 2020 Nov 13;7(11):ofaa483. Epub 2020 Oct 13.

HIV and HCC in Uganda (H2U) Consortium, Infectious Diseases Institute, Kampala, Uganda.

Background: Liver fibrosis is common among HIV-infected patients. Risk factors vary by location. Understanding this variation may inform prevention strategies. Read More

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November 2020

Interest in reducing methamphetamine and opioid use among syringe services program participants in Washington State.

Drug Alcohol Depend 2020 11 23;216:108243. Epub 2020 Aug 23.

Department of Health Services, School of Public Health, University of Washington, 1959 NE Pacific St, Seattle, WA, 98195, USA; Alcohol and Drug Abuse Institute, University of Washington, 1107 NE 45th St, Suite 120, Seattle, WA, 98105, USA.

Background: Methamphetamine use is increasing, and opioid use remains elevated in the US. Understanding interest in reducing/stopping substance use among people who inject drugs (PWID), as well as types of help wanted, can inform interventions.

Methods: Data from the 2019 Washington State Syringe Exchange Survey were used in logistic regression analyses to assess if demographics, substance use, and concern about anxiety or depression were associated with interest in reducing/stopping substance use among people whose main drug was methamphetamine or opioids. Read More

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November 2020

Low Tibial Valgization Osteotomy for More Severe Varus Ankle Arthritis.

Foot Ankle Int 2020 Sep 31;41(9):1122-1132. Epub 2020 Jul 31.

Department of Orthopedic Surgery, Inje University, Ilsan Paik Hospital, Goyang-si, Gyeonggi-do, South Korea.

Background: Low tibial valgization osteotomy with medial opening wedge (LTO) is generally indicated for ankle arthritis with a small talar tilt (TT). We addressed the following research questions: the efficacy of LTO for more significant varus ankle arthritis, the effect of additional inframalleolar correction followed by LTO, and the preoperative or operation-related factors influencing postoperative TT decrease.

Methods: We retrospectively reviewed the radiographic and clinical findings of 31 patients with more significant varus ankle arthritis (≥8 degrees) who underwent LTO or LTO plus inframalleolar correction. Read More

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September 2020

Impact of Lymph Node Yield on Survival in Surgically Treated Oropharyngeal Squamous Cell Carcinoma.

Otolaryngol Head Neck Surg 2021 01 21;164(1):146-156. Epub 2020 Jul 21.

University of Pennsylvania Health System, Philadelphia, Pennsylvania, USA.

Objectives: (1) To estimate the association between neck dissection lymph node yield (LNY) and survival among patients with surgically treated human papilloma virus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC). (2) To identify a clinically relevant quality metric for surgical treatment of HPV-related OPSCC.

Study Design: Retrospective cohort study. Read More

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January 2021

Study of the Risk and Preventive Factors for Progress of Mild Cognitive Impairment to Dementia.

Am J Alzheimers Dis Other Demen 2020 Jan-Dec;35:1533317520925324

Department of Psychiatric Control and Prevention, Shanghai Pudong New Area Mental Health Center, Tongji University School of Medicine, Shanghai, China.

Objective: To evaluate the risk factors for progress of mild cognitive impairment to dementia.

Methods: This study was based on the epidemiological survey in 2011 (No. PKJ2010-Y26) and contained 441 MCI individuals. Read More

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February 2021

Resilience factors, race/ethnicity and sleep disturbance among diverse older females with hypertension.

J Affect Disord 2020 06 3;271:255-261. Epub 2020 Apr 3.

Department of Population Health, Center for Healthful Behavior Change, New York University Langone Health, 180 Madison Avenue, 7th Floor,7-23C, New York, NY 10016, United States.

Background: This study examined the relationships between resilience and sleep disturbance in a diverse sample of older women with a history of hypertension and whether this relationship is moderated by individuals' race/ethnicity.

Methods: Sample includes 700 females from a community-based study in Brooklyn, New York with a mean age of 60.7 years (SD=6. Read More

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Presence and prognostic value of ventricular diastolic function in arrhythmogenic right ventricular cardiomyopathy.

Echocardiography 2020 11 27;37(11):1766-1773. Epub 2020 May 27.

Echocardiography Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.

Introduction: Limited data exist regarding the presence and importance of diastolic parameters in patients with arrhythmogenic right ventricular cardiomyopathy (ARVC). We sought to evaluate RV diastolic parameters and echo-based diastolic predictors of major adverse cardiovascular events (MACE).

Method: 48 patients with a definitive diagnosis of ARVC were included and followed for 6-18 months. Read More

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November 2020

Long-term Outcome of Gastric Per-Oral Endoscopic Pyloromyotomy in Treatment of Gastroparesis.

Clin Gastroenterol Hepatol 2021 Apr 22;19(4):816-824. Epub 2020 May 22.

Division of Digestive Diseases, Emory University School of Medicine, Atlanta, Georgia. Electronic address:

Background & Aims: Gastric per oral endoscopic pyloromyotomy (GPOEM) is a promising treatment for gastroparesis. There are few data on the long-term outcomes of this procedure. We investigated long-term outcomes of GPOEM treatment of patients with refractory gastroparesis. Read More

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Effect of Surgical Setting on Hospital-Reported Outcomes for Elective Lumbar Spinal Procedures: Tertiary Versus Community Hospitals.

Global Spine J 2020 Jun 16;10(4):375-383. Epub 2019 May 16.

University of Maryland School of Medicine, Baltimore, MD, USA.

Study Design: Retrospective cohort study.

Objective: As hospital compensation becomes increasingly dependent on pay-for-performance and bundled payment compensation models, hospitals seek to reduce costs and increase quality. To our knowledge, no reported data compare these measures between hospital settings for elective lumbar procedures. Read More

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DNA methylation of the 5'-UTR DAT 1 gene in Parkinson's disease patients.

Acta Neurol Scand 2020 Sep 3;142(3):275-280. Epub 2020 Jun 3.

Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University, Rome, Italy.

Objectives: The involvement of epigenetics mechanisms in the transcriptional regulation of key genes has been investigated in the initiation and progression of neurodegenerative disorders, including Parkinson's disease (PD). Among others, we, here, focused the attention on the dopamine transporter (DAT) gene playing a critical role in maintaining the integrity of dopaminergic neurons.

Materials And Methods: We performed bisulfite pyrosequencing to examine DNA methylation levels of six CpG sites in the 5'-UTR of DAT1 gene in human peripheral blood mononuclear cells (PBMCs) obtained from 101 sporadic PD patients and 59 healthy controls. Read More

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September 2020

Risk Factors for Mortality in 244 Older Adults With COVID-19 in Wuhan, China: A Retrospective Study.

J Am Geriatr Soc 2020 Jun 12;68(6):E19-E23. Epub 2020 May 12.

Department of Infectious Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

Background/objectives: Previous studies have reported that older patients may experience worse outcome(s) after infection with severe acute respiratory syndrome coronavirus-2 than younger individuals. This study aimed to identify potential risk factors for mortality in older patients with coronavirus disease 2019 (COVID-19) on admission, which may help identify those with poor prognosis at an early stage.

Design: Retrospective case-control. Read More

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Clinical Factors Associated with Apical Periodontitis Visible on Cone-beam Computed Tomography but Missed with Periapical Radiographs: A Retrospective Clinical Study.

J Endod 2020 Jun 12;46(6):832-838. Epub 2020 Apr 12.

Department of Conservative Dentistry, College of Medicine, Ewha Womans University, Seoul, Korea. Electronic address:

Introduction: Cone-beam computed tomographic (CBCT) imaging is useful in detecting apical periodontitis, which is often missed in periapical (PA) radiographs. This study aimed to identify preoperative predictors correlated with the presence of apical periodontitis visible only in CBCT images and to investigate the important characteristics of such lesions.

Methods: In total, 332 consecutive patients with both PA radiographs and CBCT images were enrolled in this study. Read More

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Predicting Lower Quarter Y-Balance Test Performance From Foot Characteristics.

J Sport Rehabil 2020 Feb 5:1-6. Epub 2020 Feb 5.

Context: The lower quarter Y-Balance Test (YBT-LQ) is associated with injury risk; however, ankle range of motion impacts YBT-LQ. Arch height and foot sensation impact static balance, but these characteristics have not yet been evaluated relative to YBT-LQ.

Objective: Determine if arch height index (AHI), forefoot sensation (SEN), and ankle dorsiflexion predict YBT-LQ composite score (CS). Read More

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February 2020

Relation of infarction location and volume to vertigo in vertebrobasilar stroke.

Brain Behav 2020 03 5;10(3):e01564. Epub 2020 Feb 5.

Department of Neurology, University Hospital of Alexandria, Alexandria, Egypt.

Objective: Vertigo is a common presentation of vertebrobasilar stroke. Anecdotal reports have shown that vertigo occurs more often in multiple than in single brainstem or cerebellar infarctions. We examined the relation between the location and volume of infarction and vertigo in patients with vertebrobasilar stroke. Read More

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The Effectiveness of Intraoperative Clip Placement in Improving Radiation Therapy Boost Targeting After Oncoplastic Surgery.

Pract Radiat Oncol 2020 Sep - Oct;10(5):e348-e356. Epub 2019 Dec 19.

Department of Radiation Oncology, Tufts Medical Center, Boston, Massachusetts. Electronic address:

Purpose: The role of surgical clips as markers of the tumor bed cavity for radiation therapy boost targeting after oncoplastic surgery is not well understood. Therefore, we sought to evaluate whether the placement of surgical clips can reduce interobserver variability in the delineation of the tumor bed cavities of oncoplastic surgery patients and ultimately determine an optimal number of clips to place.

Methods And Materials: We reviewed records of 39 women with breast cancer who underwent oncoplastic breast surgery and adjuvant radiation therapy at our institution. Read More

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December 2019

Predictors of Service Dosage, Recommendation, and Usage in an Early Childhood System of Care.

J Child Fam Stud 2019 Feb 22;28(2):599-608. Epub 2018 Nov 22.

Yale School of Medicine, New Haven, CT.

Objectives: Children and families enrolled in early childhood systems of care (SOC) present with various psychological and behavioral risk factors that may inhibit healthy development. Within a SOC, wraparound services are designed to increase families' access to numerous child-serving sectors in order to target those risk factors. This study examined whether child and family risk factors at enrollment in an early childhood SOC predicted dosage, service recommendation, and usage of recommended services. Read More

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February 2019

A New Recall of Alcohol Marketing Scale for Youth: Measurement Properties and Associations With Youth Drinking Status.

J Stud Alcohol Drugs 2019 09;80(5):563-571

Department of Pediatrics, Geisel School of Medicine at Dartmouth, Lebanon, New Hampshire.

Objective: Adolescents are exposed to alcohol marketing through traditional advertising and through newer digital media channels. Cumulative marketing exposure across channels is of concern but has been insufficiently studied. This study explores the measurement of alcohol marketing exposure across channels and whether cumulative recalled exposure is independently associated with underage drinking. Read More

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September 2019

Doppler Velocity Estimates of Internal Carotid Artery Stenosis: Angle Correction Parallel to the Color Doppler Lumen Versus Parallel to the Artery Wall.

J Ultrasound Med 2019 Dec 23;38(12):3211-3218. Epub 2019 May 23.

Wake Forest University School of Medicine, Winston-Salem, North Carolina, USA.

Objectives: We compared internal carotid artery Doppler peak systolic velocities (PSVs) measured with angle correction parallel to the artery wall (// wall) on grayscale images and parallel to the direction of blood flow (// flow) on color Doppler images.

Methods: We studied 25 internal carotid lesions with PSVs higher than 125 cm/s. The PSVs were measured in the same imaging plane, at the stenosis orifice (0 cm) and at 0. Read More

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December 2019

Serum Glucose and Potassium Ratio as Risk Factors for Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage.

J Stroke Cerebrovasc Dis 2019 Jul 3;28(7):1951-1957. Epub 2019 May 3.

Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan.

Objective: Cerebral vasospasm is associated with poor prognosis in patients with aneurysmal subarachnoid hemorrhage (SAH), and biomarkers for predicting poor prognosis have not yet been established. We attempted to clarify the relationship between serum glucose/potassium ratio and cerebral vasospasm in patients with aneurysmal SAH.

Methods: We studied 333 of 535 aneurysmal SAH patients treated between 2006 and 2016 (123 males, 210 females; mean age 59. Read More

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Choroidal thickness in thyroid-associated orbitopathy.

Clin Exp Ophthalmol 2019 Sep 20;47(7):918-924. Epub 2019 May 20.

Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong.

Importance: To investigate the choroidal thickness (CT) in patients with thyroid-associated orbitopathy (TAO).

Background: To compare CT of TAO patients and healthy subjects.

Design: Prospective cross-sectional study in a public hospital. Read More

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September 2019

Impact of Renal Artery Stent-Graft Placement on Renal Function in Chronic Aortic Dissection.

J Vasc Interv Radiol 2019 Jul 11;30(7):979-986. Epub 2019 Apr 11.

Division of Cardiovascular Surgery, Department of Surgery, Taipei Veterans General Hospital, Taiwan; Institute of Clinical Medicine, School of Medicine, National Yang Ming University, No. 201, Section 2, Shipai Road, Beitou District, Taipei City, Taiwan. Electronic address:

Purpose: To evaluate the effect of renal stent-graft placement on kidney function and size alternation in chronic aortic dissection.

Materials And Methods: Twenty-five consecutive patients with chronic aortic dissection after thoracic endovascular aortic repair who underwent renal stent-graft placement between January 2015 and December 2016 were retrospectively reviewed. Forty-three patients with chronic aortic dissection who received thoracic endovascular aortic repair in the same period were reviewed as a control group for kidney volume comparison. Read More

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Serum cholesterol positively associated with oxidative DNA damage: a propensity score-matched analysis.

Free Radic Res 2019 Apr 4;53(4):411-417. Epub 2019 Apr 4.

a Department of Preventive Medicine , School of Public Health and Management, Wenzhou Medical University , Wenzhou , China.

Oxidative DNA damage pathogenically links to some major diseases. This study aimed to comprehensively assess the association between serum total cholesterol (TC) and oxidative DNA damage based on propensity score matching (PSM) method. A total of 407 participants chronically exposed to arsenic via drinking water from China were enrolled. Read More

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Prognostic effect of serum BDNF levels in late-life depression: Moderated by childhood trauma and SSRI usage?

Psychoneuroendocrinology 2019 05 7;103:276-283. Epub 2019 Feb 7.

University of Groningen, University Medical Center Groningen, Department of Psychiatry, University of Groningen PO Box 72, 9700 AB, Groningen, the Netherlands.

Background: Brain-derived neurotrophic factor (BDNF) levels decline during depression and normalise after remission, although studies in older patient samples are inconsistent. Whether BDNF serum levels predict depression remission is unclear. We hypothesize that the predictive value of serum BDNF levels in late-life depression is moderated by selective serotonin reuptake inhibitors (SSRI) usage and early traumatization. Read More

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Impact of hospital care volume on clinical outcomes of laparoscopic radical hysterectomy for cervical cancer: A systematic review and meta-analysis.

Medicine (Baltimore) 2018 Dec;97(49):e13445

Division of Gynecologic Oncology, Obstetrics and Gynecology, Irvine Medical Center, University of California, Orange, CA.

Background: In cervical cancer, the impact of hospital volume of laparoscopic radical hysterectomy (LRH) has not been investigated systematically as in ovarian cancer.The aim of this study was to investigate the impact of hospital care volume of LRH on treatment outcomes of patients with cervical cancer.

Methods: The PubMed, Embase, and Cochrane Library databases were searched with the terms "cervical cancer," "radical hysterectomy," and "laparoscopy. Read More

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December 2018