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Contrasting the assembly of phytoplankton and zooplankton communities in a polluted semi-closed sea: Effects of marine compartments and environmental selection.

Environ Pollut 2021 Apr 29;285:117256. Epub 2021 Apr 29.

State Environmental Protection Key Laboratory of Coastal Ecosystem, National Marine Environmental Monitoring Center, Dalian, 116023, China.

Understanding the underlying mechanisms of community assembly is a major challenge in microbial ecology, particularly in communities composed of diverse organisms with different ecological characteristics. However, very little is known about the effects of marine compartments in shaping marine planktonic communities; primarily, how they are related to organism types and environmental variables. In this study, we used multiple statistical methods to explore the mechanisms driving phytoplankton and zooplankton metacommunity dynamics at the regional scale in the Bohai Sea, China. Read More

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Feasibility of Single-Stage Posterior Passive Correction and Fusion Surgery for Congenital Scoliosis in Adolescent Patients Who Have Attained Skeletal Maturity.

Asian Spine J 2021 May 7. Epub 2021 May 7.

Department of Orthopaedic Surgery, National Orthopaedic Centre of Excellence for Research and Learning, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

Study Design: Retrospective study.

Purpose: To report the perioperative and radiological outcomes of single-stage posterior passive correction and fusion (SSPPCF) in adolescent patients who present with congenital scoliosis.

Overview Of Literature: The surgical treatment for congenital scoliosis is complex. Read More

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Morphological and molecular characterization of an Elaeis oleifera (H.B.K) Cortes germplasm collection located in Ucayali, Peru.

PLoS One 2021 6;16(5):e0250445. Epub 2021 May 6.

Estación Experimental Agraria Pucallpa, Dirección de Recursos Genéticos y Biotecnología, Instituto Nacional de Innovación Agraria (INIA), Coronel Portillo, Ucayali, Perú.

The African oil palm (Elaeis guineensis Jacq) is a crop that is widely distributed in tropical regions around the world; however, this crop is subject to limitations such as rapid trunk growth and susceptibility to bud rot and red ring diseases particularly in South America. To overcome these limitations, national breeding and conservation programs have been established, and there is a need to identify parental palms from natural populations of the American oil palm (E. oleifera H. Read More

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Social zeitgebers and circadian dysrhythmia are associated with severity of symptoms of PTSD and depression in trauma-affected refugees.

Eur Arch Psychiatry Clin Neurosci 2021 May 6. Epub 2021 May 6.

Competence Centre for Transcultural Psychiatry, Mental Health Center Ballerup, Mental Health Services in the Capital Region of Denmark, Ballerup, Denmark.

The relation of aspects of rest-activity patterns, i.e., social zeitgebers, physical activity and circadian rhythm, to the severity of PTSD and depressive symptoms has not previously been studied. Read More

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Giant bilateral angiomyolipoma of the kidney.

Ann R Coll Surg Engl 2021 May 6. Epub 2021 May 6.

Maulana Azad Medical College, New Delhi, India.

Angiomyolipoma is a benign solid renal neoplasm. A giant angiomyolipoma is more than 10cm by size, but it can grow to huge proportions. Our case appears to be the third largest angiomyolipoma and the largest among bilateral giant renal angiomyolipoma in the indexed literature. Read More

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Use of School Wellness Policy Templates in One Texas Public Health Region: A Mixed-Methods Analysis.

J Sch Health 2021 May 5. Epub 2021 May 5.

The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, Austin Campus, Michael & Susan Dell Center for Healthy Living, 1616 Guadalupe St., Suite 6.300, Austin, TX, USA, 78701.

Background: Federal law requires most school districts to develop school wellness policies (SWPs), which state agencies assist in by providing templates. Templates provide standard language, which districts may edit for numerous reasons. We aimed to identify the frequency/consistency of template usage and identify the types of edits districts make when using SWP templates. Read More

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Relationship between mandibular symphysis dimensions and skeletal pattern in adults.

Folia Morphol (Warsz) 2021 May 6. Epub 2021 May 6.

Department of Orthodontics, School of Dental Medicine, University of Buffalo, NY, United States.

Background: The knowledge of dimensions of the symphysis is important for morphological and orthodontic studies. This research evaluates the association between mandibular symphysis dimensions and anteroposterior and vertical skeletal patterns in adults.

Materials And Methods: This cross-sectional cephalometric study included 90 lateral cephalograms of untreated subjects presenting for orthodontic treatment. Read More

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Normal Patterns of Histone H3K27 Methylation Require the Histone Variant H2A.Z in Neurospora crassa.

Genetics 2020 Sep;216(1):51-66

Department of Microbiology, University of Georgia, Athens, Georgia 30602.

Neurospora crassa contains a minimal Polycomb repression system, which provides rich opportunities to explore Polycomb-mediated repression across eukaryotes and enables genetic studies that can be difficult in plant and animal systems. Polycomb Repressive Complex 2 is a multi-subunit complex that deposits mono-, di-, and trimethyl groups on lysine 27 of histone H3, and trimethyl H3K27 is a molecular marker of transcriptionally repressed facultative heterochromatin. In mouse embryonic stem cells and multiple plant species, H2A. Read More

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September 2020

A real-time approach of diagnosing rice leaf disease using deep learning-based faster R-CNN framework.

PeerJ Comput Sci 2021 7;7:e432. Epub 2021 Apr 7.

Innovative Manufacturing, Mechatronics and Sports Laboratory, Faculty of Manufacturing and Mechatronic Engineering Technology, Universiti Malaysia Pahang, Pekan, Pahang, Malaysia.

The rice leaves related diseases often pose threats to the sustainable production of rice affecting many farmers around the world. Early diagnosis and appropriate remedy of the rice leaf infection is crucial in facilitating healthy growth of the rice plants to ensure adequate supply and food security to the rapidly increasing population. Therefore, machine-driven disease diagnosis systems could mitigate the limitations of the conventional methods for leaf disease diagnosis techniques that is often time-consuming, inaccurate, and expensive. Read More

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Magnitude of Gender-Based Violence and Its Associated Factors among Female Night Students in Bahir Dar City, Amhara Region, Ethiopia.

Int J Reprod Med 2021 12;2021:6694890. Epub 2021 Apr 12.

Department of Midwifery, College of Health Science, Debre Tabor University, Debre Tabor, Ethiopia.

Background: Gender-based violence (GBV) is a major public health issue that affects the health and well-being of millions of young people worldwide each year. Gender-based violence was prevalent throughout Sub-Saharan Africa. However, research in Africa is extremely diverse. Read More

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Repeated exposure to dengue virus elicits robust cross neutralizing antibodies against Zika virus in residents of Northeastern Thailand.

Sci Rep 2021 May 5;11(1):9634. Epub 2021 May 5.

Molecular Biotechnology Laboratory, School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima, 30000, Thailand.

Zika virus (ZIKV) and dengue virus (DENV) are antigenically related mosquito-borne flaviviruses. ZIKV is becoming increasingly prevalent in DENV-endemic regions, raising the possibility that pre-existing immunity to one virus could modulate the response to a heterologous virus, although whether this would be beneficial or detrimental is unclear. Here, we analyzed sera from residents of a DENV-endemic region of Thailand to determine the prevalence of DENV-elicited antibodies capable of cross-neutralizing ZIKV. Read More

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Land Cover of Early Life Environment Modulates the Risk of Type 1 Diabetes.

Diabetes Care 2021 May 5. Epub 2021 May 5.

Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland

Objective: Environmental microbial exposures have been implicated to protect against immune-mediated diseases such as type 1 diabetes. Our objective was to study the association of land cover around the early-life dwelling with the development of islet autoimmunity and type 1 diabetes to evaluate the role of environmental microbial biodiversity in the pathogenesis.

Research Design And Methods: Association between land cover types and the future risk of type 1 diabetes was studied by analyzing land cover types classified according to Coordination of Information on the Environment (CORINE) 2012 and 2000 data around the dwelling during the first year of life for 10,681 children genotyped for disease associated HLA-DQ alleles and monitored from birth in the Type 1 Diabetes Prediction and Prevention (DIPP) study. Read More

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Cancer care reform in South Africa: A case for cancer care coordination: A narrative review.

Palliat Support Care 2021 May 6:1-9. Epub 2021 May 6.

Discipline of Public Health Medicine, School of Nursing and Public Health, University of KwaZulu-Natal, Durban, South Africa.

Objective: This review provides an overview of the existing literature on the importance of care coordination for lung cancer care and other cancers in general. The review is inclusive of the burden of cancer, with a special reference to lung cancer, as well as challenges and achievements relating to cancer care coordination.

Method: We conducted a search of online databases of peer-reviewed studies published in the English language. Read More

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Epidemiology of Parkinson's Disease in Rural Gujarat, India.

Neuroepidemiology 2021 May 5:1-8. Epub 2021 May 5.

Department of Neurology, Charutar Arorgya Mandal, Shree Krishna Hospital and Pramukhswami Medical College, Bhaikaka University, Anand, India.

Introduction: In India, there have been only few published studies of Parkinson's disease (PD) showing a wide range of prevalence. We conducted this study to determine the prevalence of PD in the rural population of Gujarat, in the western region of India.

Methods: This cross-sectional descriptive study was conducted in the villages of Anand, a district of Gujarat, India, between September 2019 and February 2020. Read More

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Breast cancer survival and its prognostic factors in the United Arab Emirates: A retrospective study.

PLoS One 2021 5;16(5):e0251118. Epub 2021 May 5.

Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates.

Background: Data on breast cancer survival and its prognostic factors are lacking in the United Arab Emirates (UAE). Sociodemographic and pathologic factors have been studied widely in western populations but are very limited in this region. This study is the first to report breast cancer survival and investigate prognostic factors associated with its survival in the UAE. Read More

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Distinct expression of select and transcriptome-wide isolated 3'UTRs suggests critical roles in development and transition states.

PLoS One 2021 5;16(5):e0250669. Epub 2021 May 5.

Dept. of Biology, Stanford University, Stanford, CA, United States of America.

Mature mRNA molecules are expected to be comprised of a 5'UTR, a 3'UTR and a coding region (CDS). Unexpectedly, however, there have been multiple recent reports of widespread differential expression of mRNA 3'UTRs and their cognate coding regions (CDS), reflecting the expression of isolated 3'UTRs (i3'UTRs); these i3'UTRs can be highly expressed, often in reciprocal patterns to their cognate CDS. As with other long non-coding (lncRNAs), isolated 3'UTRs are likely to play an important role in gene regulation, but little is known about the contexts in which they are deployed. Read More

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The last battle of Anne of Brittany: Solving mass grave through an interdisciplinary approach (paleopathology, biological anthropology, history, multiple isotopes and radiocarbon dating).

PLoS One 2021 5;16(5):e0248086. Epub 2021 May 5.

Max Planck Institute for Evolutionary Anthropology, Department of Human Evolution, Leipzig, Germany.

Mass graves are usually key historical markers with strong incentive for archeological investigations. The identification of individuals buried in mass graves has long benefitted from traditional historical, archaeological, anthropological and paleopathological techniques. The addition of novel methods including genetic, genomic and isotopic geochemistry have renewed interest in solving unidentified mass graves. Read More

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The effect of beat frequency vibration on sleep latency and neural complexity: a pilot study.

IEEE Trans Neural Syst Rehabil Eng 2021 May 5;PP. Epub 2021 May 5.

Insomnia affects millions of people A bed excited with multiple vibration sources was used to explore beat frequency vibration (BFV) as a non-pharmacological treatment for insomnia. A repeated measures design pilot study of 14 participants with mild-moderate insomnia symptom severity (self-reported on the Insomnia Severity Index) was conducted to determine the effects of BFV, and traditional standing wave vibration (SWV) on sleep latency and sleep electrocortical activity. Participants were monitored using high-density electroencephalography (HD-EEG). Read More

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Clinical Case complexity in Occupational Health: Contributing Factors and a Proposed Conceptual Framework Model.

J Occup Environ Med 2021 Apr 3. Epub 2021 Apr 3.

Healthy Working Lives Group, Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, G12 8RZ, Glasgow, UK (Lalloo, Macdonald), School of Public Health, University College Cork, Cork, Ireland, T12 YN60 (Gallagher), Health Services Executive, Mid-West Region, Limerick, Ireland, V94 7X9 (McDonnell).

Objectives: Clinical case complexity is an inherent factor in occupational health (OH), yet it is poorly defined and understood. Our aim was to identify the multiple sources of complexity in OH and propose a conceptual complexity framework model for clinical OH practice.

Methods: Through a scoping review, expert panel consensus, and content analysis of OH clinical case reports, we identified relevant complexity-contributing factors (CCFs) specifically tailored to the OH setting, which we defined and validated. Read More

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National accreditation programmes for hospitals in the Eastern Mediterranean Region: Case studies from Egypt, Jordan, and Lebanon.

Int J Health Plann Manage 2021 May 5. Epub 2021 May 5.

Department of Management and Policy, Alliance Manchester Business School, Manchester, UK.

Background: Many countries use external evaluation programmes such as accreditation in order to improve quality and safety in their healthcare settings. Hospital accreditation has developed in many low-and-middle-income countries (LMICs); however, the implementation and sustainability of these programmes vary in each country. This study addresses design and implementation issues of national hospital accreditation programmes. Read More

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DOCK8-related Immunodeficiency Syndrome (DIDS): Report of Novel Mutations in Iranian Patients.

J Mol Neurosci 2021 May 4. Epub 2021 May 4.

Division of Medical Genetics, Tabriz Children's Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

DOCK8 immunodeficiency syndrome (DIDS) is a rare autosomal recessive (AR) disorder characterized by elevated serum IgE levels, eosinophilia, recurrent cutaneous infections, severe eczema, and sinopulmonary and gastrointestinal infections. This syndrome is a multisystem disease that is associated with both immune deficiency and neurological complications. In this study, we describe the clinical characteristics of two Iranian patients with DOCK8 deficiency and propose possible mechanisms for this condition. Read More

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Hemichorea-Hemiballism in A 50-Year-Old Man With Newly Diagnosed Diabetes.

AACE Clin Case Rep 2021 Mar-Apr;7(2):134-137. Epub 2020 Dec 28.

National Institute of Neurosciences and Hospital, Sher-E-Bangla Nagar, Agargaon, Dhaka 1207, Bangladesh.

Objective: Hyperglycemia may cause acute central nervous system dysfunction manifesting as agonizing involuntary movements due to insult to the basal ganglia. We report a case of hemichorea-hemiballism (HCHB) in a patient with diabetes.

Method: Clinical assessment of the patient was performed, along with laboratory tests and brain imaging. Read More

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December 2020

Exploring exchange and direct procurement strategies for Natufian food processing tools of el-Wad Terrace, Israel.

Sci Rep 2021 May 4;11(1):9480. Epub 2021 May 4.

The Zinman Institute of Archaeology, University of Haifa, Haifa, Israel.

We present the results of a detailed geochemical provenance study of 54 Natufian (ca. 15,000-11,700 cal. BP) basalt pestles from the site of el-Wad Terrace (EWT), Israel. Read More

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The Landscape of Cell-free HBV Integrations and Mutations in Cirrhosis and Hepatocellular Carcinoma Patients.

Clin Cancer Res 2021 May 4. Epub 2021 May 4.

Berry Oncology Corporation, Beijing, China.

Purpose: Intratumoral hepatitis B virus (HBV) integrations and mutations are related to hepatocellular carcinoma (HCC) progression. Circulating cell-free DNA (cfDNA) has shown itself as a powerful non-invasive biomarker for cancer. However, the HBV integration and mutation landscape on cfDNA remains unclear. Read More

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Molecular Functions of WWOX Potentially Involved in Cancer Development.

Cells 2021 Apr 29;10(5). Epub 2021 Apr 29.

Pharmacogenomics Unit, Department of Genetics, Institut Curie, 75005 Paris, France.

The WW domain-containing oxidoreductase gene () was cloned 21 years ago as a putative tumor suppressor gene mapping to chromosomal fragile site FRA16D. The localization of in a chromosomal region frequently altered in human cancers has initiated multiple current studies to establish its role in this disease. All of this work suggests that WWOX, due to its ability to interact with a large number of partners, exerts its tumor suppressive activity through a wide variety of molecular actions that are mostly cell specific. Read More

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Subtyping bovine viral diarrhea virus (BVDV): Which viral gene to choose?

Infect Genet Evol 2021 May 1:104891. Epub 2021 May 1.

Setor de Virologia, Departamento de Medicina Veterinária Preventiva, Universidade Federal de Santa Maria, Rio Grande do Sul, Brazil. Electronic address:

Bovine viral diarrhea virus-1 (BVDV-1, Pestivirus A) and BVDV-2 (Pestivirus B) have been clustered into 21 and 4 subtypes, respectively. This genetic diversity, in addition to the lack of consensus on which genomic region to use for BVDV subtyping, has resulted in conflicting classifications depending on the target analyzed. Here, we investigated which genes or UTRs would reproduce the phylogeny obtained by complete genome (CG) analyses. Read More

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Ultrashort echo time adiabatic T (UTE-Adiab-T) is sensitive to human cadaveric knee joint deformation induced by mechanical loading and unloading.

Magn Reson Imaging 2021 May 1. Epub 2021 May 1.

Department of Radiology, University of California, San Diego, CA, USA.

Purpose: The development of ultrashort echo time (UTE) MRI sequences has led to improved imaging of tissues with short T relaxation times, such as the deep layer cartilage and meniscus. UTE combined with adiabatic T preparation (UTE-Adiab-T) is an MRI measure with low sensitivity to the magic angle effect. This study aimed to investigate the sensitivity of UTE-Adiab-T to mechanical load-induced deformations in the tibiofemoral cartilage and meniscus of human cadaveric knee joints. Read More

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Physical exercise is associated with beneficial bone mineral density and body composition in young adults with childhood-onset inflammatory bowel disease.

Scand J Gastroenterol 2021 May 4:1-9. Epub 2021 May 4.

Department of Pediatrics, Institute of Clinical Sciences, The Sahlgrenska Academy at University of Gothenburg and Queen Silvia's Children's Hospital, Gothenburg, Sweden.

Background: Patients with inflammatory bowel disease (IBD) have an increased risk of compromised bone mineral density (BMD) and body composition. There are limited data on the physical exercise (PE) habits of patients with childhood-onset IBD and on the associations between PE and BMD and body composition.

Patients And Methods: In total, 72 young adults with childhood-onset IBD and 1341 normative young adult controls answered questionnaires regarding PE [hours/week (h/w)] in the last 12 months. Read More

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First Report of Anthracnose of American Ginseng caused by in Northeast China.

Plant Dis 2021 May 4. Epub 2021 May 4.

Chinese Academy of Agricultural Sciences, 12661, Institute of Special Wild Economic Animal and Plant Science, Chinese Academy of Agricultural Sciences, Juye Street No. 4899, Changchun, Jilin, China, 130112.

American ginseng () is a medicinal plant that is commercially cultivated in China. Anthracnose is a devastating disease of American ginseng, with annual production losses exceeding 20%. In July 2019, anthracnose of American ginseng was observed on 3-year-old plants in Fusong County, Jilin Province, China, the most important region of American ginseng. Read More

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GGC repeat expansions in NOTCH2NLC causing a phenotype of distal motor neuropathy and myopathy.

Ann Clin Transl Neurol 2021 May 4. Epub 2021 May 4.

Department of Neurology, Peking University First Hospital, Beijing, 100034, China.

Background: The expansion of GGC repeat in the 5' untranslated region of the NOTCH2NLC has been associated with various neurogenerative disorders of the central nervous system and, more recently, oculopharyngodistal myopathy. This study aimed to report patients with distal weakness with both neuropathic and myopathic features on electrophysiology and pathology who present GGC repeat expansions in the NOTCH2NLC.

Methods: Whole-exome sequencing (WES) and long-read sequencing were implemented to identify the candidate genes. Read More

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