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A Sustainability Analysis of Two Rapeseed Farming Ecosystems in Khorramabad, Iran Based on Emergy and Economic Analyses.

J Clean Prod 2019 Jul;226:1051-1066

Department of Agronomy, Sabzevar Branch, Islamic Azad University, Sabzevar, Iran.

In the past two decades, rapeseed farming has garnered attention, because it offers the possibility of attaining self-sufficiency in the production of edible oil, which is a strategic product for Iran. Therefore, the overarching goal of this research was to provide sound strategies to further the development of rapeseed farming and to increase the sustainability and productivity of rapeseed production systems. Progress toward this goal was made by assessing subsistence and commercial rapeseed production systems in Khorramabad, Iran during the 2017-2018 crop year using both emergy and economic indices. Read More

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Beef production from cull dairy cows: a review from culling to consumption.

J Anim Sci 2021 Jun 14. Epub 2021 Jun 14.

Department of Animal and Dairy Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.

Although more than 3 million head of dairy cows enter the food supply chain in the U.S. every year, research on this topic remains limited and scarce. Read More

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Managing mental health problems in a family and community setting: Reflections on the family physician approach and Re-imagining psychiatric education.

J Family Med Prim Care 2021 Apr 29;10(4):1639-1643. Epub 2021 Apr 29.

Founder and Director, PCMH Restore Health, Bangalore, Karnataka, India & Chair, AFPI National Centre for Primary Care Research and Policy.

Family Medicine is unique in that it recognizes the central role of the patient's context and the interplay of family dynamics, social relationships, cultural background, and economics in the causation and presentation of any illness and the response to any given treatment. While this is true across the board, it is particularly true of mental health. In this article, using a selection of stories from our daily practices as family physicians, we: (1) reflect on the role of family physicians in addressing mental health needs in the community; (2) contrast between a disease-oriented (specialist approach) and a person-oriented (family physician approach); and (3) suggest a course correction to the existing model of mental health education for both generalists (such a family physicians) and specialists (such as psychiatrists). Read More

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Chemical speciation of selected toxic metals and multivariate statistical techniques used to assess water quality of tropical Mexican Lake Chapala.

Environ Monit Assess 2021 Jun 13;193(7):418. Epub 2021 Jun 13.

Departamento de Ingeniería Química, Universidad de Guadalajara-CUCEI, Blvd. Marcelino García Barragán # 1421, esq. Calzada Olímpica, C.P. 44430, Guadalajara, Jalisco, Mexico.

Mexican Lake Chapala is used as water supply for human consumption. Consequently, water quality of this lake is of paramount importance for the lake's wellbeing. The contribution presented in this paper investigates monitoring and assessment of lake water quality using water quality index (WQI), metal chemical speciation, and multivariate statistical techniques. Read More

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Relationship between level of economic development, age and etiology of spinal cord injury: a cross-sectional survey from 22 countries.

Arch Phys Med Rehabil 2021 Jun 10. Epub 2021 Jun 10.

Department of Medical Rehabilitation, Faculty of Health Sciences, Medical University of Lodz, Poland.

Objective: To examine relationships between age and spinal cord injury (SCI) and cause of SCI, and how this depends on economic development.

Design: Cross-sectional survey.

Setting: Community, 22 countries representing all stages of economic development. Read More

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Ensuring patient and public involvement in the transition to AI-assisted mental health care: A systematic scoping review and agenda for design justice.

Health Expect 2021 Jun 12. Epub 2021 Jun 12.

Surrey Heartlands Health and Care Partnership, Guildford and Waverley CCG, Guildford, UK.

Background: Machine-learning algorithms and big data analytics, popularly known as 'artificial intelligence' (AI), are being developed and taken up globally. Patient and public involvement (PPI) in the transition to AI-assisted health care is essential for design justice based on diverse patient needs.

Objective: To inform the future development of PPI in AI-assisted health care by exploring public engagement in the conceptualization, design, development, testing, implementation, use and evaluation of AI technologies for mental health. Read More

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Pushing or Pulling Your "Poison": Clinical Correlates of Alcohol Approach and Avoidance Bias Among Inpatients Undergoing Alcohol Withdrawal Treatment.

Front Psychol 2021 25;12:663087. Epub 2021 May 25.

School of Psychology, Deakin University, Geelong, VIC, Australia.

Alcohol approach bias, the tendency to automatically move toward alcohol cues, has been observed in people who drink heavily. However, surprisingly, some alcohol-dependent patients demonstrate an alcohol avoidance bias. This inconsistency could be explained by the clinical or demographic profile of the population studied, yet this has not been examined in approach bias modification (ABM) trials to date. Read More

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Insulinoma-derived pseudo-islets for diabetes research.

Am J Physiol Cell Physiol 2021 Jun 9. Epub 2021 Jun 9.

Department of Physiology, grid.134563.6University of Arizona, Tucson, AZ, United States.

The islets of Langerhans of the pancreas are the primary endocrine organ responsible for regulating whole body glucose homeostasis. The use of isolated primary islets for research development and training requires organ resection, careful digestion and isolation of the islets from non-endocrine tissue. This process is time consuming, expensive and requires substantial expertise. Read More

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Consumer Views on Health Applications of Consumer Digital Data and Health Privacy Among US Adults: Qualitative Interview Study.

J Med Internet Res 2021 06 9;23(6):e29395. Epub 2021 Jun 9.

Department of Family Medicine and Community Health, University of Pennsylvania, Philadelphia, PA, United States.

Background: In 2020, the number of internet users surpassed 4.6 billion. Individuals who create and share digital data can leave a trail of information about their habits and preferences that collectively generate a digital footprint. Read More

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Visual gamma oscillations predict sensory sensitivity in females as they do in males.

Sci Rep 2021 Jun 8;11(1):12013. Epub 2021 Jun 8.

Center for Neurocognitive Research (MEG Center), Moscow State University of Psychology and Education, Moscow, Russian Federation.

Gamma oscillations are driven by local cortical excitatory (E)-inhibitory (I) loops and may help to characterize neural processing involving excitatory-inhibitory interactions. In the visual cortex reliable gamma oscillations can be recorded with magnetoencephalography (MEG) in the majority of individuals, which makes visual gamma an attractive candidate for biomarkers of brain disorders associated with E/I imbalance. Little is known, however, about if/how these oscillations reflect individual differences in neural excitability and associated sensory/perceptual phenomena. Read More

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Two decades of neuroscience publication trends in Africa.

Nat Commun 2021 06 8;12(1):3429. Epub 2021 Jun 8.

School of Life Sciences, University of Sussex, Brighton, UK.

Neuroscience research in Africa remains sparse. Devising new policies to boost Africa's neuroscience landscape is imperative, but these must be based on accurate data on research outputs which is largely lacking. Such data must reflect the heterogeneity of research environments across the continent's 54 countries. Read More

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Ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane: Toxicological effects on marine biota and human concerns.

J Appl Toxicol 2021 Jun 7. Epub 2021 Jun 7.

Laboratório de Modelagem Molecular & QSAR-3D (ModMolQSAR), Departamento de Fármacos e Medicamentos (DEFARMED), Faculdade de Farmácia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.

Ethylhexyl methoxycinnamate (EHMC) (CAS number: 5466-77-3) and butyl methoxydibenzoylmethane (BMDM) (CAS number: 70356-09-1) are important sunscreens. However, frequent application of large amounts of these compounds may reflect serious environmental impact, once it enters the environment through indirect release via wastewater treatment or immediate release during water activities. In this article, we reviewed the toxicological effects of EHMC and BMDM on aquatic ecosystems and the human consequences. Read More

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Exploring the relationship between mastitis risk perceptions and farmers' readiness to engage in milk recording.

Prev Vet Med 2021 May 31;193:105393. Epub 2021 May 31.

Agricultural Economic and Farm Surveys, Rural Economy & Development Programme, Teagasc Mellows Campus, Athenry, Co., Galway, H65 R718, Ireland.

The need to move towards Selective Dry Cow Therapy (SDCT) has become increasingly pertinent as a means to reduce the use of antibiotics in the dairy sector. With the EU 2022 ban on prophylactic antibiotics at drying off, practices on some farms will need to drastically change. In Ireland, one particular challenge to the sector-wide transition to SDCT is the lack of widespread uptake of milk recording across dairy farms, a decision support tool which can support mastitis control and help identify cows to select for SDCT. Read More

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Adolescent Intermittent Ethanol (AIE) Produces Sex Specific Alterations in Adult Neuroimmune Gene Expression and Ethanol Sensitivity that are independent of Ethanol Metabolism.

Neuropharmacology 2021 Jun 4:108635. Epub 2021 Jun 4.

Developmental Exposure Alcohol Research Center, Behavioral Neuroscience Program, Department of Psychology, Binghamton, NY 13902-6000. Electronic address:

The goal of the present studies was to determine long-lasting effects of adolescent intermittent ethanol (AIE), a rodent model of binge patterns of ethanol consumption, on (i) behavioral sensitivity to ethanol challenge in adulthood using the Loss of Righting Reflex (LORR) test; (ii) ethanol pharmacokinetics and ethanol-metabolizing enzyme expression when re-challenged with ethanol as adults; and (iii) induction of neuroimmune gene expression during an adult binge-like ethanol challenge. To evaluate the impact of AIE on ethanol sensitivity in adulthood, adult rats received a sedative ethanol dose of 3.5 g/kg and were tested for the LORR. Read More

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Weak association between socioeconomic Care Need Index and primary care visits per registered patient in three Swedish regions.

Scand J Prim Health Care 2021 Jun 7:1-8. Epub 2021 Jun 7.

Department of Economics, Lund University and Faculty of Business, Kristianstad University, Kristianstad, Sweden.

Objective: The objective was to examine the association between primary care consultations and a Care Need Index (CNI) used to compensate Swedish primary care practices for the extra workload associated with patients with low socioeconomic status.

Design: Observational study combining graphical analysis with linear regressions of cross-sectional administrative practice-level data.

Setting: Three Swedish regions, Västra Götaland, Skåne and Östergötland (3. Read More

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Neutral Effect of Increased Dairy Product Intake, as Part of a Lifestyle Modification Program, on Cardiometabolic Health in Adolescent Girls With Overweight/Obesity: A Secondary Analysis From a Randomized Controlled Trial.

Front Nutr 2021 21;8:673589. Epub 2021 May 21.

School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, ON, Canada.

The presence of obesity and some cardiometabolic disease risk factors in childhood and adolescence track into adulthood. Intake of dairy products has been shown to be inversely related to adiposity and cardiometabolic variables in youth. However, limited research has examined cardiometabolic disease risk factors following increased dairy product consumption as part of a lifestyle modification intervention in youth with overweight/obesity. Read More

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Assessment of Hypoxic Tissue Fraction and Prediction of Survival in Cervical Carcinoma by Dynamic Contrast-Enhanced MRI.

Front Oncol 2021 20;11:668916. Epub 2021 May 20.

Group of Radiation Biology and Tumor Physiology, Department of Radiation Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

Tumor hypoxia is a major cause of treatment resistance and poor survival in locally-advanced cervical carcinoma (LACC). It has been suggested that and maps derived by dynamic contrast-enhanced magnetic resonance imaging can provide information on the oxygen supply and oxygen consumption of tumors, but it is not clear whether and how these maps can be combined to identify tumor hypoxia. The aim of the current study was to find the optimal strategy for calculating hypoxic fraction and predicting survival from and maps in cervical carcinoma. Read More

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Tell Me Who You Vote for, and I'll Tell You Who You Are? The Associations of Political Orientation With Personality and Prosocial Behavior and the Plausibility of Evolutionary Approaches.

Front Psychol 2021 19;12:656725. Epub 2021 May 19.

Department of Psychology, University of Bonn, Bonn, Germany.

Blatantly observable in the U.S. currently, the political chasm grows, representing a prototype of political polarization in most if not all western democratic political systems. Read More

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Integrated metabolomics and proteomics analysis reveals energy metabolism disorders in the livers of sleep-deprived mice.

J Proteomics 2021 Jun 2;245:104290. Epub 2021 Jun 2.

Department of Child, Adolescent and Women's Health, School of Public Health, Capital Medical University, Beijing, China; Beijing Key Laboratory of Environmental Toxicology, Capital Medical University, Beijing, China. Electronic address:

Sleep deprivation (SD) has been linked to impaired mental and physical health, obesity, and various diseases. However, the molecular mechanism underlying the effects of SD in the liver is still unclear. To investigate the metabolome and proteome alterations in the liver, an in vivo model of SD was established based on automated random motion platform techniques by applying a strategy of 10 consecutive days of 20 h of sleep deprivation +4 h of resting. Read More

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[How do Advanced Practice Nurses participate in building health policy projects?]

Prof Inferm 2021 Jan-Mar;74(1):3-12

Professor of Nursing Science, PhD, Prof. Dr., Responsible Clinical Area, Master nursing science University of applied Sciences and Arts of Southern Switzerland, Department of Business Economics, Health and Social Care, Switzerland Corresponing Author:

Introduction: Patients' needs and the change of health professionals' roles have led researchers to reflect about the involvement of nurses in care processes development, as well as health policies. Studies confirm how advanced nursing training promotes quality of care and reduces the costs of healthcare. The introduction of the Advanced Practice Nurses (APNs) could potentially be an added value also in the Swiss healthcare context, where this figure is positioning. Read More

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Effect of surgical pleth index-guided analgesia versus conventional analgesia techniques on fentanyl consumption under multimodal analgesia in laparoscopic cholecystectomy: a prospective, randomized and controlled study.

BMC Anesthesiol 2021 Jun 4;21(1):167. Epub 2021 Jun 4.

Department of Anaesthesiology, The Fourth Affiliated Hospital, Zhejiang University, School of Medicine, 322000, Yiwu, Zhejiang, China.

Background: The Surgical Pleth Index (SPI) is an objective tool that can reflect nociception-antinociception balance and guide the use of intraoperative analgesics. Multimodal analgesia has been neglected in many previous studies. The aim of this study was to compare fentanyl consumption using SPI-guided analgesia versus conventional analgesia techniques under multimodal analgesia in laparoscopic cholecystectomy. Read More

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Income-based inequality in nationwide general health checkup participation in Japan.

Public Health 2021 May 31;195:112-117. Epub 2021 May 31.

Department of Health Education and Health Sociology, School of Public Health, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. Electronic address:

Objective: In Japan, it is mandatory for employers to provide general health checkup opportunities to employees. Although many companies have subsidized checkups for employees' dependent family members, their participation is low. We assessed income-based inequality in the participation of employees' dependents in the general health checkup. Read More

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Looking into individual choices and local realities to define adaptation options to drought and climate change.

J Environ Manage 2021 Jun 1;293:112861. Epub 2021 Jun 1.

Department of Agricultural Economics, Statistics and Business Management / CEIGRAM, Universidad Politécnica de Madrid (UPM). ETSIAAB, Avda. Puerta Hierro 2, 28040, Madrid, Spain. Electronic address:

Climate change adaptation choices defined by local communities reflect individual risk perception and contextual factors. This study examines how local contextual environmental factors contribute to individual choices for adapting to water scarcity in three locations in central Spain. The study evaluates citizens' choices by audience segmentation and explore the role of geographical location in segments' engagement with adaptation and adaptation measure preference. Read More

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Societal return on investment may greatly exceed financial return on investment in neurotechnology-based therapies: A case study in epilepsy therapy development.

Surg Neurol Int 2021 19;12:180. Epub 2021 Apr 19.

Department of Neurosurgery, Loma Linda University, Loma Linda, California, United States.

Background: This research study is an economic analysis of a neurotechnology-based translational research and development venture focused on the development of a therapy for patients with epilepsy. In the conceptualization, planning, financing, and execution of neurotechnology ventures, many factors come into play in determining value and ability to secure financing at each stage of the venture. Conventionally, these have included factors that determine the return on investment for the stakeholders of the venture, most notably the investors and the team members, the former investing hard earned capital, and the latter investing significant portions of their professional careers. Read More

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Biomechanical Aspects of the Foot Arch, Body Balance and Body Weight Composition of Boys Training Football.

Int J Environ Res Public Health 2021 05 10;18(9). Epub 2021 May 10.

Department of Tourism, Recreation and Ecology, University of Warmia and Mazury, 10-719 Olsztyn, Poland.

The aim of the study is to assess the body balance and podological parameters and body composition of young footballers in the context of the control of football training. The study examined the distribution of the pressure of the part of the foot on the ground, the arch of the foot, and the analysis of the body composition of the boys. The pressure center for both feet and the whole body was also examined. Read More

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Differentiated Thyroid Cancer: A Health Economic Review.

Cancers (Basel) 2021 May 7;13(9). Epub 2021 May 7.

Department of Endocrine & Thyroid Surgery, Hammersmith Hospital, London W12 0HS, UK.

The incidence of differentiated thyroid cancer (DTC) is rising, mainly because of an increased detection of asymptomatic thyroid nodularity revealed by the liberal use of thyroid ultrasound. This review aims to reflect on the health economic considerations associated with the increasing diagnosis and treatment of DTC. Overdiagnosis and the resulting overtreatment have led to more surgical procedures, increasing health care and patients' costs, and a large pool of community-dwelling thyroid cancer follow-up patients. Read More

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A Two-Stage Hybrid Default Discriminant Model Based on Deep Forest.

Entropy (Basel) 2021 May 8;23(5). Epub 2021 May 8.

School of Business Administration, Northeastern University, Shenyang 110819, China.

the credit scoring model is an effective tool for banks and other financial institutions to distinguish potential default borrowers. The credit scoring model represented by machine learning methods such as deep learning performs well in terms of the accuracy of default discrimination, but the model itself also has many shortcomings such as many hyperparameters and large dependence on big data. There is still a lot of room to improve its interpretability and robustness. Read More

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Evaluation of Formal and Informal Spatial Coastal Area Planning Process in Baltic Sea Region.

Int J Environ Res Public Health 2021 05 4;18(9). Epub 2021 May 4.

Norrköping Municipality, 601 81 Norrköping, Sweden.

Many shared views of both scholars and practitioners reflect spatial planning as a place-creating process that must be understood from a multi-level perspective. Formal and informal planning modes have variations in planning practices in different countries. In this study, we aimed to evaluate the interaction of formal and informal spatial planning in the frame of the spatial planning system in the Baltic Sea region. Read More

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'What You See is All There is': The Importance of Heuristics in Cost-Benefit Analysis (CBA) and Social Return on Investment (SROI) in the Evaluation of Public Health Interventions.

Appl Health Econ Health Policy 2021 May 31. Epub 2021 May 31.

Centre for Health Economics and Medicines Evaluation (CHEME), School of Health Sciences, Bangor University, Bangor, Gwynedd, LL57 2PZ, UK.

Health economists are currently debating, with some suspicion, the relative merits of cost-benefit analysis (CBA), grounded in theoretical welfare economics, and the proliferation of social return on investment (SROI), a pragmatic approach of developing a triple-bottom line (social, environmental and financial), but not grounded in welfare theory. We argue, in rather existential terms, that there is a need to understand the role of heuristics, or prior beliefs, in current 'best practice' in CBA and SROI. A taxonomy of CBA and SROI is presented, which summarises the origins of the methods, reporting guidance, publication checklist of quality of reporting, who is wanting these analytical approaches, and policy decision rule present. Read More

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The Effects of a Single Freeze-Thaw Cycle on Concentrations of Nutritional, Noncommunicable Disease, and Inflammatory Biomarkers in Serum Samples.

J Lab Physicians 2021 Mar 24;13(1):6-13. Epub 2021 May 24.

Department of Cardiac Biochemistry, All India Institute of Medical Sciences, Delhi, India.

 The stability of biological samples is vital for reliable measurements of biomarkers in large-scale survey settings, which may be affected by freeze-thaw procedures. We examined the effect of a single freeze-thaw cycle on 13 nutritional, noncommunicable diseases (NCD), and inflammatory bioanalytes in serum samples.  Blood samples were collected from 70 subjects centrifuged after 30 minutes and aliquoted immediately. Read More

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