216 results match your criteria red propolis


Effect of Non-hydrogen Peroxide on Antibacterial Activity of Malaysian Honey against .

J Pharm Bioallied Sci 2020 Nov 5;12(Suppl 2):S831-S835. Epub 2020 Nov 5.

Department of Microbiology, Umaru Musa Yar'adua University Katsina, Katsina, Nigeria.

Introduction: Stingless bee is an insect that belongs to the family Apidae. Its name is based on its disability of stinging. It has a high product of honey and propolis by which are commonly referred to as stingless bee honey and stingless bee propolis. Read More

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November 2020

Red propolis effect analysis of dairy calves health based on Weibull regression model with long-term survivors.

Res Vet Sci 2021 Mar 29;136:464-471. Epub 2021 Mar 29.

Department of Animal Sciences, Luiz de Queiroz College of Agriculture, University of São Paulo, Brazil, Pá dua Dias Avenue, 11, Piracicaba, SP, Brazil.

Diarrhea is the most common cause of mortality and morbidity in dairy calves during the first weeks of life. It is responsible for the majority of costs related to animal death and treatments, as well as lower productivity due to reduced weight gain. Therefore, studies that focus on strategies to reduce diarrhea incidence and to improve animal welfare are very important for the dairy industry. Read More

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Antibacterial Activity of Propolis-Embedded Zeolite Nanocomposites for Implant Application.

Materials (Basel) 2021 Mar 3;14(5). Epub 2021 Mar 3.

Smart Medical Convergence Technology Support Center, Chosun University, Gwangju 61012, Korea.

This study investigates the potential of propolis-embedded zeolite nanocomposites for dental implant application. Propolis-embedded zeolite nanocomposites were fabricated by complexation of propolis and zeolites. Then, they were pelleted with Poly(L-lactide) (PLA)/poly(ε-caprolactone) (PCL) polymer for the fabrication of a dental implant. Read More

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A validated HPLC-UV method for the analysis of phenolic compounds in Brazilian red propolis and Dalbergia ecastaphyllum.

J Pharm Biomed Anal 2021 May 16;198:114029. Epub 2021 Mar 16.

School of Pharmaceutical Sciences of Ribeirão Preto, Ribeirão Preto, University of São Paulo, Brazil. Electronic address:

Propolis is a natural product produced from the interaction between bees and plants. Brazilian red propolis results from Apis mellifera collection of resins from two plant species, being Dalbergia ecastaphyllum(L.) Taub, Fabaceae, the primary botanical source, containing isoflavonoids and other characteristic phenolic compounds. Read More

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Nonclinical Toxicological Studies of Brazilian Red Propolis and Its Primary Botanical Source .

Chem Res Toxicol 2021 Apr 15;34(4):1024-1033. Epub 2021 Mar 15.

Laboratory of Pharmacognosy, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Av. do Café S/N, Ribeirão Preto, SP 14040-930, Brazil.

Propolis is one of the most widely used products in traditional medicine. One of the most prominent types of Brazilian propolis is the red one, whose primary botanical source is (L.) Taub. Read More

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Active Antioxidant Phenolics from Brazilian Red Propolis: An Optimization Study for Their Recovery and Identification by LC-ESI-QTOF-MS/MS.

Antioxidants (Basel) 2021 Feb 16;10(2). Epub 2021 Feb 16.

Center for Nuclear Energy in Agriculture, University of São Paulo, Piracicaba, SP 13416-000, Brazil.

Brazilian red propolis (BRP) is a natural product widely known for its phenolic composition and strong antioxidant properties. In this study, we used the Box-Behnken Design (BBD) with Surface Response Methodology to optimize the extraction conditions for total phenolic content (TPC) and Trolox equivalent antioxidant capacity(TEAC) of bioactive phenolics from BRP. The extraction time, ethanol/water concentration and temperature, were tested. Read More

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February 2021

Polyphenols and Brazilian red propolis incorporated into a total-etching adhesive system help in maintaining bonding durability.

Heliyon 2021 Feb 19;7(2):e06237. Epub 2021 Feb 19.

Department of Chemistry, Federal Institute of Alagoas, Rua Mizael Domingues, 75, Campus Maceió, CEP 57020-600, Maceió, Alagoas, Brazil.

Objectives: The aim of this study was to evaluate the degree of conversion and bond strength of a commercial dental adhesive modified by the incorporation of quercetin, resveratrol (RES), and Brazilian red propolis (BRP).

Methods: BRP markers were identified using ultra-performance liquid chromatography coupled with a diode array detector, and the antioxidant activity (AAO) of the three substances was analyzed. Single Bond 2 adhesive (3M ESPE) was modified by adding BRP, quercetin, and RES, separately, at 20 μg/mL, 250 μg/mL, and 500 μg/mL, respectively. Read More

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February 2021

Propolis reduces the stemness of head and neck squamous cell carcinoma.

Arch Oral Biol 2021 May 19;125:105087. Epub 2021 Feb 19.

Department of Cariology, Restorative Sciences, Endodontics, University of Michigan School of Dentistry, Ann Arbor, MI, USA; Department of Biomedical Engineering, University of Michigan College of Engineering, Ann Arbor, MI, USA; Department of Otolaryngology, University of Michigan School of Medicine, Ann Arbor, MI, USA.

Objective: To evaluate the effect of Brazilian propolis on head and neck cancer stem cells in vitro.

Methods: Head and neck squamous cell carcinoma (HNSCC) cell lines (UM-SCC-17B and UM-SCC-74A), human keratinocytes (HK), and primary human dermal microvascular endothelial cells (HDMEC) were treated with 0.5, 5. Read More

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Antimicrobial properties, mechanics, and fluoride release of ionomeric cements modified by red propolis.

Angle Orthod 2021 Feb 25. Epub 2021 Feb 25.

Objectives: To evaluate the antimicrobial activity, mechanical properties, and fluoride release capacity of glass ionomer cement (GIC) used for cementing orthodontic bands and modified by ethanolic extract of red propolis (EERP) in different concentrations.

Materials And Methods: Two orthodontic GICs containing EERP at 10%, 25%, and 50%, were used. The following assays were carried out: cell viability tests against Streptococcus mutans and Candida albicans, diametral tensile strength, compressive strength, shear bond strength, microhardness, and fluoride release capacity. Read More

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February 2021

Functional food mixtures: Inhibition of lipid peroxidation, HMGCoA reductase, and ACAT2 in hypercholesterolemia-induced rats.

Food Sci Nutr 2021 Feb 3;9(2):875-887. Epub 2020 Dec 3.

Department of Pathology Faculty of Medicine and Health Sciences Universiti Putra Malaysia (UPM) Serdang Malaysia.

Mixtures of selected functional foods (MSFF) were composed of (fermented soybean), red yeast rice extract, , oat fiber, garlic, bee pollen, and propolis as anti-hypercholesterolemic were studied. The goal of this study was to determine the bioactive compounds in these mixtures and their cholesterol-lowering potential effects (biochemical profiles, lipid peroxidation, liver tissue histopathology, and enzymatic activity analysis; HMGCoA reductase and ACAT2. The LC-MS/MS analysis showed that bioactive compounds such as Monacolin K, naringin, tocopherol, and glutamate, which have potential as anti-hypercholesterolemic agents, were present in these functional food mixtures. Read More

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February 2021

In vitro antimicrobial activity and comparison of the herbal extracts and sodium hypochlorite against primary plaque colonizers.

FEMS Microbiol Lett 2021 Mar;368(4)

Harbin Medical University, Institute of Biological Information Science and Technology, Heilongjiang Province, 150001, People's Republic of China.

NaClO is not suitable as a root canal irrigant because of its cytotoxicity. Good biocompatibility irrigants are required to have antibacterial activity. Many herbal products like Bee glue, Noni juice and Azadirachta indica have such properties. Read More

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Inhibitory effect of Brazilian red propolis on planktonic and biofilm forms of Clostridioides difficile.

Anaerobe 2021 Jan 27;69:102322. Epub 2021 Jan 27.

Group of Applied Medical Microbiology - GrAMM, Postgraduate Program in Medical Microbiology, School of Medicine, Federal University of Ceara, Fortaleza, CE, Brazil; Laboratory of Emerging and Reemerging Pathogens, Postgraduate Program in Medical Microbiology, School of Medicine, Federal University of Ceará, Fortaleza, CE, Brazil.

Clostridioides difficile is a Gram-positive, spore-forming, anaerobic bacillus which is the leading cause of health-care-associated infective diarrhea. The rising incidence of antibiotic resistance in pathogens such as C. difficile makes researches on alternative antibacterial products very important, especially those exploring natural products like propolis. Read More

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January 2021

Experimental evaluation of intra-abdominal adhesions comparing two different intraperitoneal meshes and the effect of a natural anti-inflammatory product on their formation.

Acta Cir Bras 2021 20;35(12):e351205. Epub 2021 Jan 20.

PhD, Full Professor, Postgraduate Program in Health and Environment, Universidade Tiradentes, Aracaju-SE, Brazil.

Purpose: In laparoscopic incisional hernia repair, meshes with a tissue-separating barrier are positioned intraperitoneally. Despite this property, the close contact between mesh and viscera involves a risk of adhesion formation. Some natural products, such as red propolis (RP), could reduce these adhesions owing to their anti-inflammatory properties. Read More

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January 2021

Biosynthesis and characterization of gold nanoparticles using Brazilian red propolis and evaluation of its antimicrobial and anticancer activities.

Sci Rep 2021 Jan 21;11(1):1974. Epub 2021 Jan 21.

GNanoBio, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Avenida Do Café S/nº, Ribeirão Preto, São Paulo, 14040-903, Brazil.

Gold nanoparticles (AuNPs) are highlighted due to their low toxicity, compatibility with the human body, high surface area to volume ratio, and surfaces that can be easily modified with ligands. Biosynthesis of AuNPs using plant extract is considered a simple, low-cost, and eco-friendly approach. Brazilian Red Propolis (BRP), a product of bees, exhibits anti-inflammatory, anti-tumor, antioxidant, and antimicrobial activities. Read More

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January 2021

The Cardiovascular Therapeutic Potential of Propolis-A Comprehensive Review.

Biology (Basel) 2021 Jan 4;10(1). Epub 2021 Jan 4.

CBIOS (Research Center for Biosciences and Health Technologies), Universidade Lusófona de Humanidades e Tecnologias, Campo Grande 376, 1749-024 Lisboa, Portugal.

Owing to its chemical richness, propolis has a myriad of therapeutic properties. To the authors' knowledge, this is the first comprehensive review paper on propolis to focus exclusively on its major effects for cardiovascular health. The propolis compound varieties with the most promising therapeutic benefits and their respective physiological mechanisms will be discussed. Read More

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January 2021

Effect of xylitol tablets with and without red propolis on salivary parameters, dental biofilm and sensory acceptability of adolescents: a randomized crossover clinical trial.

Biofouling 2020 11 17;36(10):1182-1195. Epub 2020 Dec 17.

Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.

The effect of xylitol tablets with (XPT) and without (XT) red propolis on salivary parameters, dental biofilm and acceptability of adolescents was evaluated through a blinded randomized crossover clinical trial. Healthy volunteers were allocated in the XPT and XT groups with a 30-day washout period for consumption of two tablets/dayfor seven days. An increase in salivary parameters was only observed immediately after tablet consumption, without differences between XPT and XT. Read More

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November 2020

New Insights for Red Propolis of Alagoas-Chemical Constituents, Topical Membrane Formulations and Their Physicochemical and Biological Properties.

Molecules 2020 Dec 9;25(24). Epub 2020 Dec 9.

Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceió, Alagoas 57072-970, Brazil.

The main objectives of this study were to evaluate the chemical constitution and allergenic potential of red propolis extract (RPE). They were evaluated, using high performance liquid chromatography (HPLC) and the release of β-hexosaminidase, respectively. A plethora of biologically active polyphenols and the absence of allergic responses were evinced. Read More

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December 2020

The gastroprotective effect of red propolis extract from Northeastern Brazil and the role of its isolated compounds.

J Ethnopharmacol 2021 Mar 25;267:113623. Epub 2020 Nov 25.

School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil. Electronic address:

Ethnopharmacological Relevance: Propolis has been used in folk medicine to treat gastric disorders for centuries. However, although studies have been conducted to validate the gastroprotective and anti-ulcer activity of some types of propolis, red propolis activity remains unknown.

Aim Of The Study: The present study aimed to evaluate the gastroprotective effect of the hydroalcoholic extract of red propolis (HERP), its mode of action, and the main compounds involved in its activity, therefore contributing to validate the chemical and pharmacological potential of this product. Read More

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and , Main Plant Sources for Bioactive Properties in Green and Red Brazilian Propolis.

Plants (Basel) 2020 Nov 21;9(11). Epub 2020 Nov 21.

Life Science Institute "King Michael I of Romania", University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, 400372 Cluj-Napoca, Romania.

Nowadays, propolis is used as a highly valuable product in alternative medicine for improving health or treating a large spectrum of pathologies, an ingredient in pharmaceutical products, and also as a food additive. Different vegetal materials are collected by honeybees and mixed with wax and other own substances in order to obtain the final product, called propolis. It is known as the bee product with the widest chemical composition due to the raw material collected by the bees. Read More

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November 2020

Pancreatic Cancer (PDAC): Introduction of Evidence-Based Complementary Measures into Integrative Clinical Management.

Cancers (Basel) 2020 Oct 23;12(11). Epub 2020 Oct 23.

Department of Life Sciences, Neuroscience Solutions to Cancer Research Group, Imperial College London, South Kensington Campus, London SW7 2AZ, UK.

The most common form of pancreatic cancer is pancreatic ductal adenocarcinoma (PDAC), which comprises some 85% of all cases. Currently, this is the fourth highest cause of cancer mortality worldwide and its incidence is rising steeply. Commonly applied clinical therapies offer limited chance of a lasting cure and the five-year survival rate is one of the lowest of the commonly occurring cancers. Read More

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October 2020

Supercritical Extraction of Red Propolis: Operational Conditions and Chemical Characterization.

Molecules 2020 Oct 20;25(20). Epub 2020 Oct 20.

School of Pharmacy, Federal University of Bahia (UFBA), Barão de Jeremoabo Street, 147, Salvador 40110-100, Bahia, Brazil.

The objective of this study was to determine the best operational conditions for obtaining red propolis extract with high antioxidant potential through supercritical fluid extraction (SFE) technology, using carbon dioxide (CO) as the supercritical fluid and ethanol as the cosolvent. The following parameters were studied: overall extraction curve, S/F (mass of CO/mass of sample), cosolvent percentage (0, 1, 2 and 4%) and global yield isotherms as a function of different pressures (250, 350 and 450 bar) and temperatures (31.7, 40 and 50 °C). Read More

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October 2020

Biocompatibility of Ionomeric Cements Modified by Red Propolis: A Morphological and Immunohistochemical Analysis.

J Adhes Dent 2020 ;22(5):515-522

Purpose: To evaluate the biocompatibility in rat subcutaneous tissue of conventional orthodontic cements, Riva (R) and Meron (M), modified by the addition of ethanolic extract of red propolis (EERP), at different concentrations and time intervals.

Materials And Methods: One hundred eight male adult Wistar rats were used, distributed in nine groups of cements with added EERP at the concentrations used (C-control, MC, M10, M25, M50, RC, R10, R25, and R50). The rats were sacrificed after 3 time intervals (7, 15, and 30 days). Read More

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October 2020

protective effect of topical nanoemulgels containing Brazilian red propolis benzophenones against UV-induced skin damage.

Photochem Photobiol Sci 2020 Oct;19(10):1460-1469

Programa de Pós-graduação em Ciências Farmacêuticas da Universidade Federal do Rio Grande do Sul, Porto Alegre, RS 90610-000, Brazil.

The overexposure of the skin to ultraviolet (UV) radiation may lead to oxidative stress, resulting in severe damage. The prevention of skin injuries through the topical application of natural compounds rich in antioxidants, such as propolis extracts, has shown promising results. In Brazil, the "red propolis" extract has stood out due to its complex constitution, based mainly on polyprenylated benzophenones (BZP). Read More

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October 2020

Red Propolis and Its Dyslipidemic Regulator Formononetin: Evaluation of Antioxidant Activity and Gastroprotective Effects in Rat Model of Gastric Ulcer.

Nutrients 2020 Sep 26;12(10). Epub 2020 Sep 26.

University of Tiradentes, Av. Murilo Dantas, 300, Aracaju CEP 49032-490, Sergipe, Brazil.

Propolis has various pharmacological properties of clinical interest, and is also considered a functional food. In particular, hydroalcoholic extracts of red propolis (HERP), together with its isoflavonoid formononetin, have recognized antioxidant and anti-inflammatory properties, with known added value against dyslipidemia. In this study, we report the gastroprotective effects of HERP (50-500 mg/kg, p. Read More

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September 2020

Effect of the Solvent on Propolis Phenolic Profile and its Antifungal, Antioxidant, and In Vitro Cytoprotective Activity in Human Erythrocytes Under Oxidative Stress.

Molecules 2020 Sep 17;25(18). Epub 2020 Sep 17.

Department of Chemistry, Faculty of Forestry and Wood Technology, Poznań University of Life Sciences, Wojska Polskiego 75, 60625 Poznań, Poland.

Propolis is a natural bee product with various beneficial biological effects. The health-promoting properties of propolis depend on its chemical composition, particularly the presence of phenolic compounds. The aim of this study was to evaluate the relationship between extraction solvent (acetone 100%, ethanol 70% and 96%) and the antifungal, antioxidant, and cytoprotective activity of the extracts obtained from propolis. Read More

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September 2020

Brazilian red propolis exhibits antiparasitic properties in vitro and reduces worm burden and egg production in an mouse model harboring either early or chronic Schistosoma mansoni infection.

J Ethnopharmacol 2021 Jan 9;264:113387. Epub 2020 Sep 9.

Núcleo de Pesquisa Em Doenças Negligenciadas, Universidade Guarulhos, Guarulhos, SP, Brazil. Electronic address:

Ethnopharmacological Relevance: Propolis has been used in folk medicine for thousands of years and, in the past few decades, it has attracted renewed interest. Although propolis has been traditionally used in many communities worldwide against parasitic diseases, its effect against Schistosoma mansoni infection remains unclear.

Aim Of The Study: To demonstrate the effects of Brazilian red propolis on Schistosoma mansoni ex vivo and in an animal model of schistosomiasis. Read More

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January 2021

Red propolis hydroalcoholic extract inhibits the formation of biofilms on denture surface.

J Clin Exp Dent 2020 Jul 1;12(7):e626-e631. Epub 2020 Jul 1.

Department of Clinical and Social Odontology, Federal University of Paraíba, João Pessoa, PB, Brazil.

Background: To evaluate the antifungal activity of the red propolis hydroalcoholic extract (RPHE) against biofilms.

Material And Methods: The minimum inhibitory and fungicidal concentrations (MIC and MFC) of the RPHE were determined by the microdilution technique. biofilms were formed on the surface of resin specimens preconditioned with artificial saliva (1h). Read More

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Brazilian Red Propolis Is as Effective as Amoxicillin in Controlling Red-Complex of Multispecies Subgingival Mature Biofilm In Vitro.

Antibiotics (Basel) 2020 Jul 22;9(8). Epub 2020 Jul 22.

Dental Research Division, Guarulhos University, Guarulhos, São Paulo, Guarulhos 07023-070, Brazil.

This study investigated the effects of Brazilian Red Propolis (BRP) extract on seven-day-old multispecies subgingival biofilms. Mixed biofilm cultures containing 31 species associated with periodontal health or disease were grown for six days on a Calgary device. Then, mature biofilms were treated for 24 h with BRP extract at different concentrations (200-1600 µg/mL), amoxicillin (AMOXI) at 54 µg/mL (positive control) or vehicle (negative control). Read More

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The combination of Brazilian red propolis and recombinant protein rCP01850 in the immunoprophylaxis of Corynebacterium pseudotuberculosis infection in mice.

Microb Pathog 2020 Dec 20;149:104354. Epub 2020 Jun 20.

Universidade Federal de Pelotas (UFPel), Campus Capão Do Leão, Centro de Desenvolvimento Tecnológico (CDTec), Capão Do Leão, Brazil. Electronic address:

The immunomodulatory properties of Brazilian red propolis (BRP) have been already described. Also, propolis have been proved to have antibacterial activity on Corynebacterium pseudotuberculosis. An adjuvant effect of red propolis oil was able to induce a significant anti-C. Read More

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December 2020

Antioxidant and antimicrobial activity of red propolis embedded mesoporous silica nanoparticles.

Drug Dev Ind Pharm 2020 Jul;46(7):1199-1208

Laboratory of Characterization and Microscopy of Materials, Institute of Physics, Postgraduate Program in Materials Sciences, Center of Technology, Federal University of Alagoas (UFAL), Maceió, Brazil.

This work brings the promise of MCM-41 mesoporous silica as a vehicle for red propolis for the development of controlled release drugs and delivery to a specific target site. The synthesis of MCM-41 by the sol-gel method with a pore size of approximately 3.6 nm and the incorporation of red propolis extract by the physical adsorption method in ethanolic medium were easily accomplished with around 15% encapsulation. Read More

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