33,339 results match your criteria recurrent acute


Periprocedural management and clinical outcomes of invasive procedures after venous thromboembolism: from the COMMAND VTE registry.

J Thromb Thrombolysis 2021 Sep 15. Epub 2021 Sep 15.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, 54 Shogoin Kawahara-cho, Sakyo-ku, Kyoto, 606-8507, Japan.

Anticoagulation therapy is prescribed for the prevention of recurrence in patients with venous thromboembolism, which could be temporarily interrupted during invasive procedures. The COMMAND VTE Registry is a multicenter registry enrolling 3027 consecutive patients with acute symptomatic VTE in Japan between January 2010 and August 2014. We identified patients who underwent invasive procedures during the entire follow-up period and evaluated periprocedural managements and clinical outcomes at 30 days after invasive procedures. Read More

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September 2021

Acute posterior multifocal placoid pigment epitheliopathy (APMPPE).

J Ophthalmic Inflamm Infect 2021 Nov 1;11(1):31. Epub 2021 Nov 1.

Department of Uveitis, Moorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK.

Background: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disease, affecting the inner choroid and the outer retina. Recent advances in multimodal imaging have been important in the understanding of the pathophysiology of the disease, allowing a better characterization of the morphology of this condition.

Methods: Narrative review. Read More

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November 2021

Mycophenolate Mofetil and Plasmapheresis: A Treatment Option for Severe Insulin Resistance caused by Insulin Antibodies.

AACE Clin Case Rep 2021 Sep-Oct;7(5):307-309. Epub 2021 Mar 13.

Division of Endocrinology, Diabetes and Metabolism, Icahn School of Medicine at Mount Sinai, New York, New York.

Objective: Insulin antibody (IA)-mediated insulin resistance (IR) is a rare condition for which immunosuppressive regimens have been described. However, these raise the risk of infection, and the drugs may not be effectively metabolized in patients with liver disease. A 61-year old male with type 2 diabetes mellitus and antibody-mediated IR who required >800 units of daily insulin presented with acute decompensation of his preexisting cirrhosis from recurrent diabetic ketoacidosis. Read More

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Paraperitoneal herniation of the ureter.

Radiol Case Rep 2021 Nov 3;16(11):3414-3417. Epub 2021 Sep 3.

Department of General surgery, GITAM Institute of Medical Sciences and Research, Visakhapatnam, India.

Ureteral herniation into the scrotum is rare and often associated with congenital abnormalities or postoperative anatomic changes. A high index of suspicion is needed to avoid intraoperative ureteric injuries. A 50-year-old man with ureteric herniation into an inguinoscrotal hernia reported acute left flank pain and had a history of recurrent urinary tract infections. Read More

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November 2021

Neglected roles of IgG Fc-binding protein secreted from airway mucin-producing cells in protecting against SARS-CoV-2 infection.

Innate Immun 2021 Sep 15:17534259211043159. Epub 2021 Sep 15.

Department of Diagnostic Pathology, Shimada General Medical Center, Shimada, Shizuoka, Japan.

Both innate immunity and acquired immunity are involved in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. The induction of Abs that neutralize the virus has been described, and certain Abs against endemic coronaviruses may cross-react with SARS-CoV-2. Detailed mechanisms to protect against the pandemic of SARS-CoV-2 remain unresolved. Read More

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September 2021

AQP4-IgG positive paraneoplastic NMOSD: A case report and review.

Brain Behav 2021 Sep 14:e32282. Epub 2021 Sep 14.

Department of Neurology, The First Hospital of Jilin University, Changchun, Jilin Province, P. R. China.

Introduction: Neuromyelitis optica spectrum disorder (NMOSD; also known as Devic syndrome) is a clinical syndrome of central nervous system characterized by immune mediated attacks of acute optic neuritis and myelitis. Paraneoplastic neurological syndrome is a group of nervous system disorders resulting from the remote immune effects of malignant neoplasm. NMOSD occurs mostly in young people, and tumor is not a common cause, especially recurrent tumor. Read More

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September 2021

Clinical outcomes of severe tricuspid valve infective endocarditis related to intravenous drug abuse - a case series.

Acta Cardiol 2021 Sep 14:1-6. Epub 2021 Sep 14.

Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

Background: Right-sided infective endocarditis (IE) related to intravenous drug use (IVDU) can follow an acute fulminant course. However, there is limited information on its longer-term clinical outcomes.

Aim And Methods: We assessed a cohort of consecutive patients who presented with IVDU complicated by severe tricuspid valve regurgitation to determine their presentation, treatment, and long-term outcomes. Read More

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September 2021

Intrapulmonary arterio-venous fistula - unusual early complication of wedge resection.

Ann Thorac Surg 2021 Sep 10. Epub 2021 Sep 10.

Department of Pathology, John Paul II Hospital, Cracow, Poland.

We present a case of an arterio-venous fistula that developed in the early postoperative course after wedge resection of the right upper lobe. A 57-year old male treated for acute myeloid leukemia was referred from the hematology department because of a right upper lobe tumor. Wedge resection was performed. Read More

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September 2021

Anti-inflammatory Therapies for Coronary Heart Disease: A Systematic Review and Meta-Analysis.

Front Cardiovasc Med 2021 25;8:726341. Epub 2021 Aug 25.

Department of Cardiovascular Medicine, Chinese PLA General Hospital, Chinese PLA Medical School, Beijing, China.

Anti-inflammatory therapy has been proposed as a promising treatment for coronary heart disease (CHD) that could reduce residual inflammation risk (RIR) and therefore major adverse cardiovascular events. We implemented a systematic review and meta-analysis of randomized controlled trials (RCTs) to assess the clinical benefits of anti-inflammatory agents in patients with CHD based on secondary cardiovascular prevention. We systemically searched the PubMed, Embase, and Cochrane Library databases for RCTs (published between Jan 1, 1950, and June 1, 2021; no language restrictions) that focused on anti-inflammatory therapy for coronary heart disease. Read More

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EUS in Pediatrics: A Multicenter Experience and Review.

Front Pediatr 2021 25;9:709461. Epub 2021 Aug 25.

Cedars-Sinai Medical Center, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA, United States.

Endoscopic ultrasound (EUS) is a well-established tool used in the evaluation and treatment of a wide range of pathologies in adult medicine. EUS in pediatrics has been shown to be safe and technically effective, and its use continues to evolve. This article aims to describe the EUS experience at our tertiary-care centers with regard to safety, technical success, and its impact in clinical management. Read More

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Abdominal Cocoon Syndrome: A Laparoscopic Approach.

Cureus 2021 Jul 31;13(7):e16787. Epub 2021 Jul 31.

Internal Medicine, Shifa International Hospital Islamabad, Islamabad, PAK.

Sclerosing encapsulating peritonitis, or abdominal cocoon syndrome (ACS), is a rare cause of intestinal obstruction in which the small bowel is encapsulated by a fibro-collagenous membrane. We present the case of a 29-year-old male who presented to us with acute intestinal obstruction. The imaging performed suggested the presence of ACS. Read More

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Cervical schwannoma with acute worsening and intratumoral hemorrhage.

Surg Neurol Int 2021 16;12:409. Epub 2021 Aug 16.

Department of Neurosurgery, University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States.

Background: Primary spinal tumors are rare and include schwannomas. In the cervical region, these lesions can cause pain, radiculopathy, and/or myelopathy.

Case Description: A 53-year-old male presented with 9 months of chronic neck pain and left upper extremity radiculopathy/myelopathy. Read More

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Cervical neuromyelitis optica with thoracic ependymoma.

Surg Neurol Int 2021 9;12:396. Epub 2021 Aug 9.

Department of General Medicine, Sengkang General Hospital, Singapore.

Background: The occurrence of cervical neuromyelitis optica (NMO) in a patient with a thoracic ependymoma is uncommon. Here, we present a patient with a spinal ependymoma who developed the new onset of NMO 2 months later.

Case Description: A 66-year-old male presented with right lower limb weakness. Read More

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Efficacy and safety of endoscopic transpapillary gallbladder drainage in acute cholecystitis: An updated meta-analysis.

World J Gastrointest Endosc 2021 Aug;13(8):345-355

Department of Gastroenterology and Hepatology, University of Illinois College of Medicine at Peoria, Peoria, IL 61637, United States.

Background: Percutaneous transhepatic gallbladder drainage has been the most frequently performed treatment for acute cholecystitis for patients who are not candidates for surgery. Endoscopic transpapillary gallbladder drainage (ETGBD) has evolved into an alternative treatment. There have been numerous retrospective and prospective studies evaluating ETGBD for acute cholecystitis, though results have been variable. Read More

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Vogt-Koyanagi-Harada disease during prolonged intermittent steroid therapy for chronic obstructive pulmonary disease: a case report.

Pan Afr Med J 2021 3;39:101. Epub 2021 Jun 3.

Department of Radiology, BGS Global Institute of Medical Sciences, Bangalore, India.

Vogt-Koyanagi-Harada Disease (VKHD) is a rare systemic granulomatous autoimmune condition that affects melanocyte-rich organs including the eyes, inner ears, meninges, skin, and hair. VKHD causes chronic uveal inflammation and a loss in visual acuity in some patients. Patients generally respond well to steroid therapy. Read More

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Elevated Serum Inflammatory Markers in Subacute Stroke Are Associated With Clinical Outcome but Not Modified by Aerobic Fitness Training: Results of the Randomized Controlled Trial.

Front Neurol 2021 26;12:713018. Epub 2021 Aug 26.

Center for Stroke Research Berlin, Charité - Universitätsmedizin Berlin, Berlin, Germany.

Inflammatory markers, such as C-reactive Protein (CRP), Interleukin-6 (IL-6), tumor necrosis factor (TNF)-alpha and fibrinogen, are upregulated following acute stroke. Studies have shown associations of these biomarkers with increased mortality, recurrent vascular risk, and poor functional outcome. It is suggested that physical fitness training may play a role in decreasing long-term inflammatory activity and supports tissue recovery. Read More

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Can imported cold food cause COVID-19 recurrent outbreaks? A review.

Environ Chem Lett 2021 Sep 7:1-11. Epub 2021 Sep 7.

School of Economics and Management, Southeast University, Nanjing, 211189 China.

The coronavirus disease 2019 (COVID-19) pandemic is still spreading all over the world. Although China quickly brought the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) under control in 2020, sporadic outbreaks have recurred from time to time. Outbreaks since June 2020 have suggested that the imported cold food supply chain is a major cause for the recurrence and spread of COVID-19. Read More

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September 2021

Safe Thrombolysis During Pregnancy for Recurrent Acute Ischaemic Stroke Due to Concomitant Isolated Left Ventricular Non-Compaction and Bilateral Foetal Posterior Communicating Arteries.

Int Med Case Rep J 2021 1;14:591-595. Epub 2021 Sep 1.

Department of Medicine, Faculty of Health Sciences, Aga Khan University Medical College of East Africa, Nairobi, Kenya.

Isolated left ventricular non-compaction (ILVNC) is a rare congenital cardiomyopathy and is associated with arrhythmias, heart failure and thromboembolism including ischaemic stroke. Pregnancy is a relative contraindication to thrombolysis for acute ischaemic stroke, although case reports suggest the treatment can be given in selected cases. We report a case of recurrent cryptogenic strokes in a 36-year-old female who was thrombolysed with good outcome at 37 weeks' gestation and was eventually found to have ILVNC as the cause. Read More

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September 2021

Recurrent Pyroglutamic Acidosis in the Context of Undiagnosed Liver Cirrhosis-A Case Report.

J Clin Exp Hepatol 2021 Sep-Oct;11(5):623-627. Epub 2020 Oct 17.

Department of Gastroenterology and Hepatology, Birmingham City Hospital, Birmingham, United Kingdom.

Metabolic associated fatty liver disease, previously known as nonalcoholic fatty liver disease, is the most common cause of chronic liver disease across all ethnic groups; however, it remains enormously underestimated. Sepsis, hepatotoxic medications and malnutrition in the acute settings on top of unknown cirrhosis can lead to decompensation and various metabolic complications. Pyroglutamic acidosis is a rarely recognised cause for unexplained high anion gap metabolic acidosis that is felt to be frequently underdiagnosed. Read More

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October 2020

Human urinary kallidinogenase in acute ischemic stroke: A single-arm, multicenter, phase IV study (RESK study).

CNS Neurosci Ther 2021 Sep 12. Epub 2021 Sep 12.

Department of Neurology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Aims: Human urinary kallidinogenase (HUK) has shown favorable efficacies in acute ischemic stroke (AIS) treatment. We sought confirmation of the safety and efficacy of HUK for AIS in a large population.

Methods: RESK study enrolled patients with AIS of anterior circulation to receive HUK infusion. Read More

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September 2021

The Effect of Supervision in Vestibular Rehabilitation in Patients with Acute or Chronic Unilateral Vestibular Dysfunction: A Systematic Review.

Otol Neurotol 2021 09 10. Epub 2021 Sep 10.

Otorhinolaryngology, Head & Neck Surgery Department, University Hospital of Larisa, Greece

Objective: The investigation of supervised vestibular rehabilitation treatment role for individuals with dizziness and imbalance due to peripheral, unilateral vestibular disorders.

Databases Reviewed: Cochrane, PubMed, and Physiotherapy Evidence Database (PEDro) were utilized to identify relevant studies.

Methods: The key search terms used were "Vestibular Rehabilitation and Unilateral Vestibular Hypofunction," "Vestibular Rehabilitation and Unilateral Vestibular Loss," and "Vestibular Rehabilitation and Supervision. Read More

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September 2021

Reconstruction of Extensive Periorbital Defects With Pericranial Flap.

J Craniofac Surg 2021 Sep 10. Epub 2021 Sep 10.

Department of Plastic, Reconstructive and Aesthetic Surgery, Medical Faculty, Mersin University, Mersin Ophthalmology Department of Health Sciences, University Adana City Hospital, Adana, Turkey.

Abstract: Wide excision of recurrent malignant tumors of periorbital region leaves deep and large composite defects, requiring a reconstruction to restore both the form and function of the eyelids. In this study, a pericranial flap was utilized in the reconstruction of large, complex defects of periorbital region.This study included 5 patients who underwent wide excision of recurrent large medial canthus and supraorbital rim malignant tumors. Read More

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September 2021

Inhibition of p38 MAP Kinase in Patients with ST-Elevation Myocardial Infarction - Findings from the LATITUDE TIMI 60 Trial.

Am Heart J 2021 Sep 8. Epub 2021 Sep 8.

Brigham and Women's Hospital, Boston, MA; TIMI Study Group, Boston, MA. Electronic address:

Background: p38 mitogen activated kinase (MAPK) mediates the response to pro-inflammatory cytokines following myocardial infarction (MI) and is inhibited by losmapimod.

Methods: LATITUDE-TIMI 60 (ClinicalTrials.gov NCT02145468) randomized patients with MI to losmapimod or placebo for 12 weeks (24 weeks total follow-up). Read More

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September 2021

Cerebral Venous Sinus Thrombosis in a Child with Lesch-Nyhan Syndrome.

Neurol India 2021 Jul-Aug;69(4):1021-1023

Child Neurology Division, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

Lesch-Nyhan syndrome is a rare neurometabolic condition characterized by progressive choreoathetosis, intellectual disability, and peculiar manifestations like self-mutilation. Occasional case reports in adults have suggested an association between Lesch-Nyhan syndrome and hypercoagulability; however, no such report of either a venous or arterial stroke in children with Lesch-Nyhan Syndrome exists in literature. We present a 3-year-old boy with global developmental delay, dystonic posturing, choreoathetoid movements, and self-mutilation involving fingers and lips. Read More

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September 2021

Predictors of Concomitant Coronary Artery Disease and Major Cardiovascular Events in Patients with Acute Ischemic Stroke.

Neurol India 2021 Jul-Aug;69(4):916-922

Department of Cardiology, Marmara University School of Medicine, Istanbul, Turkey.

Background: Coronary artery disease (CAD) and ischemic stroke share the same risk factors.

Objective: The aim of the study was to explore the prevalence and predictors of concomitant CAD in acute ischemic stroke patients.

Methods: One hundred and five patients (64. Read More

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September 2021

A new therapeutic approach with tocilizumab in a 39-year-old patient with recurrent diabetic myonecrosis.

Mod Rheumatol Case Rep 2021 Sep 10. Epub 2021 Sep 10.

Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

We report the case of a 39-year-old female patient with acute painful swelling of the left thigh and symmetric muscle weakness in both upper legs. The patient had a history of long-standing, poorly controlled type 1 diabetes which required dialysis. Serum inflammatory markers were highly elevated. Read More

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September 2021

Outcomes for Patients with Anterior Myocardial Infarction and Prior Cardiac Arrest in the Home Automated External Defibrillator Trial (HAT).

Resuscitation 2021 Sep 6. Epub 2021 Sep 6.

Division of Cardiology, University of Washington, Seattle, WA, USA; Seattle Institute for Cardiac Research, Seattle, WA, USA.

Background: Patients with sudden cardiac arrest occurring in the acute phase of myocardial infarction (MI-SCA) are believed to be at similar risk of death after revascularization compared with MI patients without SCA (MI-no SCA). Among patients with anterior MI, we examined whether those with MI-SCA were at greater risk of all-cause mortality or sudden cardiac death (SCD) than MI-no SCA patients.

Methods: The Home Automated External Defibrillator Trial enrolled patients with anterior MI who had not received or were candidates for an implantable cardioverter defibrillator (ICD). Read More

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September 2021

Severity of pulmonary embolism at initial diagnosis and long-term clinical outcomes: From the COMMAND VTE Registry.

Int J Cardiol 2021 Sep 7. Epub 2021 Sep 7.

Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Kyoto, Japan. Electronic address:

Background: There is a paucity of data on the long-term clinical outcomes according to the severity of pulmonary embolism (PE) at initial diagnosis.

Methods: The COMMAND VTE Registry is a multicenter registry enrolling 3027 consecutive patients with acute symptomatic venous thromboembolism (VTE). After excluding 1312 patients without PE, the current study population consisted of 1715 patients with PE, who were divided into 3 groups according to the clinical severity; massive PE, sub-massive PE and low-risk PE. Read More

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September 2021

Suppression of acute heart failure rehospitalization by biventricular pacing in wide QRS and mid-range ejection fraction.

ESC Heart Fail 2021 Sep 9. Epub 2021 Sep 9.

Department of Cardiology and Clinical Examination, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama, Yufu, Oita, 879-5593, Japan.

We present a 66-year-old male patient with heart failure, mid-range ejection fraction and QRS widening suffering from recurrent hospitalization due to acute heart failure. We measured intra-cardiac pressure by cardiac catheterization to clearly demonstrate the augmentation of afterload by a vasoconstricting drug induced increase of left ventricular end-diastolic blood pressure and pulmonary capillary wedge pressure with pulmonary arterial V-wave augmentation (indicator of worsening of mitral regurgitation). Because the patient was considered as refractory to optimal medication, cardiac resynchronization therapy (CRT) was performed. Read More

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September 2021

Early anticoagulation in atrial fibrillation-related acute ischaemic stroke: efficacy and safety profile.

J Neurol 2021 Sep 9. Epub 2021 Sep 9.

Department of Surgery and Physiology, Faculty of Medicine of the University of Porto, Alameda Prof. Hernâni Monteiro, 4200-319, Porto, Portugal.

Objectives: To evaluate the effects of early anticoagulation on functional outcome, recurrent ischaemic events and haemorrhagic complications in Atrial Fibrillation (AF)-related acute ischaemic strokes (AIS).

Materials And Methods: We retrospectively evaluated patients hospitalised in a Stroke Unit due to AF-related AIS. Patients were divided according to anticoagulation initiation timing (0-4 days, 5-14 days, no anticoagulation by the 14th day). Read More

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September 2021