64,442 results match your criteria recurrence rates

Analysis of Clinical Characteristics and Prognosis of Patients With Periocular Malignant Melanoma in Korea.

J Craniofac Surg 2021 Jul 20. Epub 2021 Jul 20.

Department of Ophthalmology and Visual Science, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul Department of Ophthalmology, Hospital, National Cancer Center, Gyeonggi-do, South Korea.

Objective: To report the clinical features of 20 patients with malignant melanoma and to evaluate the survival and prognosis of patients with malignant melanoma in Korea.

Methods And Analysis: The medical records of 20 patients with malignant melanoma treated between March 2004 and March 2020 were reviewed retrospectively. The demographic data, clinical characteristics, and outcomes were also reviewed. Read More

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The efficacy and safety of left atrial low-voltage area guided ablation for recurrence prevention compared to pulmonary vein isolation alone in patients with persistent atrial fibrillation trial: Design and rationale.

Clin Cardiol 2021 Jul 22. Epub 2021 Jul 22.

Department of Cardiovascular Medicine, Osaka University Graduate School of Medicine, Suita, Japan.

Recurrence rates of atrial fibrillation (AF) after pulmonary vein isolation (PVI) are higher in patients with a left atrial low-voltage area (LVA) than those without. However, the efficacy of LVA guided ablation is still unknown. The purpose of this study-the Efficacy and Safety of Left Atrial Low-voltage Area Guided Ablation for Recurrence Prevention Compared to Pulmonary Vein Isolation Alone in Patients with Persistent Atrial Fibrillation trial (SUPPRESS-AF trial)-is to elucidate whether LVA guided ablation in addition to PVI is superior to PVI alone in patients with persistent AF. Read More

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Validation of the risk factors for primary control of early T-stage laryngeal, oropharyngeal, and hypopharyngeal squamous cell carcinoma by transoral surgery: a prospective observational study.

Int J Clin Oncol 2021 Jul 21. Epub 2021 Jul 21.

Department of Otorhinolaryngology, Head and Neck Surgery, Yokohama City University School of Medicine, 3-9 Fukuura, Kanazawa-ku, Yokohama, 236-0004, Japan.

Background: We had previously identified the following risk factors for insufficient control of early T-stage head and neck cancer by transoral surgery (TOS): (1) tumor thickness > 7 mm on enhanced computed tomography (CT), and (2) poor differentiation in pathological examination. We subsequently used a different patient cohort to validate the usefulness of these factors in determining the need for adaptation of TOS.

Study Setting: A prospective observational study METHODS: Patients who received TOS as a definitive treatment between April 1, 2016 and September 30, 2020 were included. Read More

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Development of a predictive model for extragastric recurrence after curative resection for early gastric cancer.

Gastric Cancer 2021 Jul 21. Epub 2021 Jul 21.

Department of Radiology, Seoul National University Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

Background: Stratification of patients who undergo curative resection for early gastric cancer (EGC) is warranted due to the heterogeneity in the risk of developing extragastric recurrence (EGR). Therefore, we aimed to stratify the need for postoperative surveillance for EGR detection in patients with EGC by developing a model for predicting EGR-free survival.

Methods: This retrospective cohort study included patients who underwent postoperative surveillance after curative resection of EGC (n = 4149). Read More

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Male sex is not an independent risk factor for recurrence of differentiated thyroid cancer: a propensity score-matching study.

Sci Rep 2021 Jul 21;11(1):14908. Epub 2021 Jul 21.

Department of Surgery, College of Medicine, The Catholic University of Korea, 06591, Seoul, Republic of Korea.

Male patients have a significantly higher prevalence of advanced-stage thyroid cancer. However, sex differences in the risk of differentiated thyroid carcinoma (DTC) recurrence have not been fully elucidated. Therefore, the present study aimed to investigate male sex as a prognostic factor for DTC. Read More

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PAX8 lineage-driven T cell engaging antibody for the treatment of high-grade serous ovarian cancer.

Sci Rep 2021 Jul 21;11(1):14841. Epub 2021 Jul 21.

NIBR Biologics Center, Novartis Institutes for Biomedical Research, Cambridge, MA, USA.

High-grade serous ovarian cancers (HGSOC) represent the most common subtype of ovarian malignancies. Due to the frequency of late-stage diagnosis and high rates of recurrence following standard of care treatments, novel therapies are needed to promote durable responses. We investigated the anti-tumor activity of CD3 T cell engaging bispecific antibodies (TCBs) directed against the PAX8 lineage-driven HGSOC tumor antigen LYPD1 and demonstrated that anti-LYPD1 TCBs induce T cell activation and promote in vivo tumor growth inhibition in LYPD1-expressing HGSOC. Read More

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[Analysis of the efficacy and prognostic factors of 1 637 esophageal cancer patients treated with intensity-modulated radiotherapy].

Zhonghua Zhong Liu Za Zhi 2021 Jun;43(6):678-684

Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To summarize survival outcomes and prognostic factors in esophageal cancer (EC) patients treated with intensity-modulated radiotherapy (IMRT). A retrospective analysis was performed on the clinical and follow-up data of 1 637 patients with EC who were admitted to our hospital from January 2005 to December 2017 and met the inclusion criteria.The 5-year overall survival (OS), progression-free survival (PFS) and pattern of recurrence were analyzed. Read More

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[Treatment and prognosis of retroperitoneal liposarcoma with multiple primary tumor].

Zhonghua Zhong Liu Za Zhi 2021 Jun;43(6):674-677

Department of Retroperitoneal Tumor Surgery, Peking University International Hospital, Beijing 102206, China.

To investigate the multiple origin of retroperitoneal liposarcoma and its postoperative prognosis. A total of 49 retroperitoneal liposarcoma patients underwent total (ipsilateral) retroperitoneal lipectomy in our center from May 2017 to December 2019 were recruited. Clinical data and the follow-up information were reviewed and the origin and prognosis were analyzed. Read More

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[Relationship of operation manner and postoperative recurrence of hepatocellular carcinoma].

Zhonghua Zhong Liu Za Zhi 2021 Jun;43(6):635-637

Department of Hepatobiliary, Pancreas and Spleen Surgery, the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China.

Hepatocellular carcinoma (HCC) owns the high morbidity and mortality rates. Surgical resection is still the major pathway for the longer survival of HCC patients. Postoperative recurrence and metastasis have become the key impairment of prognosis of HCC patients. Read More

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[Comparison on efficacy between fascia-oriented versus vascular-oriented lateral lymph node dissection in patients with rectal cancer].

Zhonghua Wei Chang Wai Ke Za Zhi 2021 Jul;24(7):611-618

National Cancer Center, National Clinical Research Center for Cancer, Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To compare the postoperative function, the short-term and long-term outcomes between fascia-oriented and vascular-oriented lateral lymph node dissection (LLND) in patients with rectal cancer. A retrospective cohort study was performed. Clinical data of patients who received total mesorectal excision (TME) with LLND at National Cancer Center, Cancer Hospital of Chinese Academy of Medical Science from January 2014 to December 2019 were retrospectively collected. Read More

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[Radical surgery for colon cancer guided by membrane anatomy theory].

B Luo K Wang

Zhonghua Wei Chang Wai Ke Za Zhi 2021 Jul;24(7):581-586

Department of Gastrointestinal Surgery, Sichuan Provincial Peoples' Hospital, Chengdu 610072, China.

Like other solid tumors, colon cancer surgery has undergone a century-old journey from lumpectomy to organ resection and then to lymphadenectomy. From the Toldt fascia to complete mesenteric resection, and from local resection to D3 radical treatment, local recurrence rates have been reduced, but remain a nuisance to surgeons and patients. Based on the theory of membrane anatomy, radical surgery for colon cancer will focus more on removing the mesocolon from the mesentery bed while maintaining the integrity of the posterior fascia to avoid the occurrence of "fifth metastasis" as much as possible. Read More

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C-reactive protein and thyroid-stimulating hormone levels as risk factors for hypothyroidism in patients with subacute thyroiditis.

Endocr Connect 2021 Jul 1. Epub 2021 Jul 1.

N Zhang, Zhejiang University School of Medicine Sir Run Run Shaw Hospital, Hangzhou, 310016, China.

Objective: This study was designed to explore the relationships between the clinical characteristics and outcomes of patients with subacute thyroiditis (SAT).

Design: This is a single-center retrospective study.

Patients: Eighty-nine patients with SAT who were hospitalized in the Sir Run Run Shaw Hospital in Zhejiang, China, from October 2014 to September 2020 were included. Read More

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Intravitreal anti-vascular endothelial growth factor treatment for inflammatory choroidal neovascularization in non-infectious uveitis.

Am J Ophthalmol 2021 Jul 18. Epub 2021 Jul 18.

Moorfields Eye Hospital, London, UK; UCL Institute of Ophthalmology, London, UK; Ophthalmology Department, Carmel Medical Center, Technion, Institute of Technology, Haifa, Israel.

Purpose: To compare visual outcome and recurrence rates of eyes with non-infectious inflammatory CNV treated with or without anti-VEGF injections and immunosuppression.

Design: Retrospective, non-randomized clinical study METHODS: : Participants: Patients with CNV secondary to non-infectious inflammatory causes who attended uveitis clinics at Moorfields Eye Hospital between January 2000 and April 2016. Data was gathered from the clinical notes of all subjects examined in clinic. Read More

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Clinical presentation and survival outcomes of well-differentiated thyroid cancer in Filipinos.

Cancer Med 2021 Jul 21. Epub 2021 Jul 21.

Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, USA.

Background: Filipinos have higher recurrence rates compared to other racial/ethnic groups, which might suggest a higher propensity for aggressive disease. The goal of this study was to perform a population-based analysis of disease extent at diagnosis and survival outcomes in Filipino patients with well-differentiated thyroid cancer relative to other racial/ethnic groups.

Methods: The study cohort comprised adult patients with well-differentiated thyroid cancer diagnosed between 2004 and 2015, identified in the California Cancer Registry. Read More

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Known and new facts on basal cell carcinoma.

J Dtsch Dermatol Ges 2021 Jul;19(7):1021-1041

University Hospital for Dermatology, Venereology, and Allergology, Medical University Innsbruck, Austria.

Basal cell carcinoma (BCC) is the most common malignant tumor in light-skinned people and amounts to about 75 % of all cases of skin cancer. Increasing incidence rates have been reported for decades all over the world. The main risk factors include UV radiation, male sex, light skin type, advanced age, long-term immunosuppression, a positive individual or family history, and certain genodermatoses. Read More

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Contemporary management of locoregionally advanced melanoma in Australia and New Zealand and the role of adjuvant systemic therapy.

ANZ J Surg 2021 Aug;91 Suppl 2:3-13

Melanoma Institute Australia, The University of Sydney and Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.

Australia and New Zealand have the highest incidence and mortality rates for melanoma in the world. Local surgery is still the standard treatment of primary cutaneous melanoma, and it is therefore important that surgeons understand the optimal care pathways for patients with melanoma. Accurate staging is critical to ensure a reliable assessment of prognosis and to guide treatment selection. Read More

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Surgical interventions for management of benign parotid tumors: A systematic review and network meta-analysis.

Head Neck 2021 Jul 20. Epub 2021 Jul 20.

Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.

The impact of the extent of parotid surgery on postoperative complications has long been considered a topic of controversy. The aim of the current network meta-analysis (NMA) is to answer the following questions: (1) Does the extent of surgical resection of benign parotid tumors increase the risk of postoperative complications? (2) What is the best surgical intervention for treatment of benign parotid tumors that can provide an acceptable balance between tumor recurrence rate and other postoperative complications? A comprehensive search on PubMed, Embase, Scopus, and Cochrane library was conducted to identify the eligible studies. The outcome was the incidence of tumor recurrence, facial nerve weakness (temporary [TFW] or permanent [PFP]), Frey's syndrome (FS), sialocele, and salivary fistula. Read More

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Outcomes of redo-transversus abdominis release for abdominal wall reconstruction.

Hernia 2021 Jul 21. Epub 2021 Jul 21.

Department of General Surgery, Cleveland Clinic Center for Abdominal Core Health, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, A100, A10-133, Cleveland, OH, 44195, US.

Background: Transversus abdominis release (TAR) is increasingly used to address complex ventral hernias; consequently, associated complications are seen more frequently. Our hernia center has a growing experience with redo-transversus abdominis release (redo-TAR) to address large, complex hernia recurrences after failed TAR. Here, we describe our outcomes after abdominal wall reconstruction with redo-TAR. Read More

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Arq Gastroenterol 2021 Jul 16. Epub 2021 Jul 16.

Hospital 9 de Julho, Serviço de Endoscopia, São Paulo, SP, Brasil.

Background: Duodenal papilla neuroendocrine tumors (DP-NET) are rare. Surgical therapy may be recommended for their treatment. However, they have high rates of morbidity and mortality. Read More

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Venous ulcer healing treated with conventional therapy and adjuvant laser: is there a difference?

Rev Bras Enferm 2021 14;74(3):e20201117. Epub 2021 Jul 14.

Universidade Federal do Rio Grande do Sul. Porto Alegre, Rio Grande do Sul, Brazil.

Objectives: to evaluate the effects of venous ulcer healing in patients after six months of conventional treatment and adjuvant low-power laser therapy.

Methods: prospective cohort study nested in a randomized clinical trial with 38 patients, allocated into an intervention group (conventional treatment and adjuvant laser therapy) and a control group (conventional treatment). Patients were followed up as outpatients, sociodemographic and clinical variables were collected, and indicators of the outcomes Wound healing: secondary intention (1103) and Tissue integrity: skin and mucous membranes(1101) of the Nursing Outcomes Classification. Read More

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Both "Vitamin L for Life" and "One Milligram of Satan": A Multi-Perspective Qualitative Exploration of Adjuvant Endocrine Therapy Use after Breast Cancer.

Curr Oncol 2021 Jul 5;28(4):2496-2515. Epub 2021 Jul 5.

Department of Psychology, University of Calgary, Calgary, AB T2N 1N4, Canada.

Adjuvant endocrine therapy (AET) is recommended after hormone receptor-positive breast cancer to reduce risk of recurrence, but adherence is sub-optimal in many women. Behavioral interventions have been ineffective in improving adherence rates to AET. This qualitative descriptive study investigates factors that support women in AET use and suggestions for interventions to improve AET use and management. Read More

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Role of surveillance screening in detecting tumor recurrence after treatment of childhood cancers.

Turk Arch Pediatr 2021 Mar 6;56(2):147-151. Epub 2021 Jan 6.

Department of Pediatric Hematology Oncology, Atılım University Faculty of Medicine, Ankara, Turkey.

Objective: As the survival rates in children with cancer reach up to 80%, this improvement in survival increases the number of patients under follow-up. After cancer treatment is completed, patients are taken to follow-up surveillance to ensure the early detection of recurrence and the late effects of treatments. The frequency and necessity of surveillance screening tests are controversial. Read More

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Trimodality Treatment for Muscle-Invasive Bladder Cancer: An Institutional Experience.

Adv Radiat Oncol 2021 Sep-Oct;6(5):100718. Epub 2021 May 20.

Departments of Radiation Oncology.

Purpose: As an alternative to radical cystectomy, tri-modality treatment (TMT) is an effective treatment approach for selected patients with muscle-invasive bladder cancer (MIBC). The purpose of this report is to contribute to the literature by summarizing institutional outcomes of a bladder-preserving TMT approach for patients with MIBC.

Methods And Materials: Patients treated with TMT for MIBC from 1998 to 2019 were identified. Read More

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Comparison of chondrosarcoma cases: current clinical situations among institutions.

Int J Health Sci (Qassim) 2021 Jul-Aug;15(4):42-49

Department of Spinal Surgery, General Hospital of Ningxia Medical University, Ningxia Medical University 804 Shengli Street, Xingqing District, Yinchuan, 75000, Ningxia, People's Republic of China.

Objective: Chondrosarcoma is a rare tumor that has a variable biological characteristic, and its treatment is controversial. We performed a comparison review of different regional institutions series to assess the clinical outcome of patients.

Methods: A retrospective review of 33 chondrosarcomas (Grades I, II, and III) patient data since 2013, compared with 15 author's total 868 patients published literature results to find more about clinical and statistical advantages and similarities with author institute cases. Read More

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Evaluation of the 10 Years' Association Between DXA Screening and Mortality in Patients Who Received Vertebroplasty in the Taiwan Population.

Risk Manag Healthc Policy 2021 14;14:2995-3001. Epub 2021 Jul 14.

School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.

Background: Osteoporotic fractures are a significant cause of morbidity and mortality affecting population worldwide. All guidelines recommended vertebral fracture assessment by dual-energy X-ray absorptiometry (DXA). This study aimed at evaluation of any associated benefits of screening with DXA in patients who had received vertebroplasty in Taiwan. Read More

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Surgical technique and outcomes following coronal-sparing glans resurfacing for benign and malignant penile lesions.

Int J Impot Res 2021 Jul 20. Epub 2021 Jul 20.

Institute of Andrology, Department of Urology, University College London Hospitals NHS Trust, London, UK.

The aim of this study is to describe the outcomes for a modified glans-resurfacing technique for benign and malignant penile conditions in which the uninvolved glans corona is preserved in order to maintain glans erogenous sensation. A total of 13 patients underwent coronal-sparing glans resurfacing (CSGR), with follow-up every 3 months for ≥2 years. Positive surgical margin and local recurrence (LR) rates were evaluated. Read More

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Recurrence in infantile tibia vara (Blount disease) after high tibia and fibula osteotomy.

J Pediatr Orthop B 2021 Jul 19. Epub 2021 Jul 19.

Division of Orthopaedic Surgery, Department of Surgery, University of the Witwatersrand, Johannesburg, South Africa.

Objectives: Infantile Tibia Vara (ITV or Blount disease) often recurs after surgical correction of the deformity. Vastly different recurrence rates have been reported in the literature. The main objective of this study was to identify any risk factors for the recurrence of ITV following high tibia and fibula valgus osteotomy. Read More

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Efficacy and safety of endoscopic resection techniques of large colorectal lesions: experience of a referral center in Italy.

Eur J Gastroenterol Hepatol 2021 Jul 19. Epub 2021 Jul 19.

Digestive Endoscopy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS Università Cattolica del Sacro Cuore, CERTT - Centre for Endoscopic Research, Therapeutics and Training, Rome, Italy.

Background: Endoscopic mucosal resection and submucosal dissection (ESD) are treatments of choice for superficial neoplastic colorectal lesions. Only a few studies have compared these techniques.

Aim: To compare the efficacy and safety of endoscopic piecemeal mucosal resection (EPMR), ESD and hybrid-endoscopic submucosal dissection (H-ESD) of large colorectal lesions in a Western endoscopic center. Read More

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The utility of underwater endoscopic mucosal resection for nonpolypoid superficial nonampullary duodenal epithelial tumors ≤20 mm.

Gastrointest Endosc 2021 Jul 17. Epub 2021 Jul 17.

Department of Gastroenterology, Graduate School of Medicine, Chiba University.

Background And Aims: The application of underwater endoscopic mucosal resection (UEMR) for nonpolypoid superficial nonampullary duodenal epithelial tumors (SNADET) has not been comprehensively assessed. Therefore, the current study aimed to validate the efficacy of UEMR versus conventional endoscopic mucosal resection (EMR) and cap-assisted endoscopic mucosal resection (EMRC) for SNADET measuring ≤20 mm.

Methods: We retrospectively analyzed patients with sporadic nonpolypoid SNADET measuring ≤20 mm. Read More

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Arthroscopic cystectomy for Baker's cysts with and without one-way valve lesions: incidence of one-way valve lesion, associated pathologies, and clinical outcomes.

Arch Orthop Trauma Surg 2021 Jul 20. Epub 2021 Jul 20.

Department of Orthopaedic Surgery, Korea University Ansan Hospital, Gyeonggi-do, Republic of Korea.

Introduction: A one-way valve lesion plays an important role in the formation of Baker's cysts and serves as an important landmark for accessing these cysts during arthroscopic surgery. This study aimed to investigate the incidence of one-way valve lesions and their effect on clinical outcomes in patients who underwent arthroscopic cystectomy for Baker's cysts.

Materials And Methods: Patients who underwent arthroscopic cystectomy for Baker's cysts between June 2005 and November 2017 were retrospectively reviewed. Read More

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