20,001 results match your criteria rectal examination

Transperineal core-needle biopsy of a rectal subepithelial lesion guided by endorectal ultrasound after contrast-enhanced ultrasound: A case report.

World J Gastroenterol 2021 Apr;27(13):1354-1361

Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China.

Background: Rectal subepithelial lesions (SELs) are commonly seen in endoscopic examination, generally manifested as bumps with a smooth surface. Precise preoperative diagnoses for rectal SELs are difficult because abnormal tissues are not easily to be obtained by regular endoscopic forceps biopsy. Traditional guidance modalities of preoperative biopsy, including endoscopic ultrasound, computed tomography, and transabdominal ultrasound, are often unsatisfactory. Read More

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Digital rectal examination in palpable rectal cancer: expert panel consensus on key elements and analysis of a case series.

Br J Surg 2021 Apr 8. Epub 2021 Apr 8.

Department of Surgery, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada.

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Paediatrics: how to manage functional constipation.

Drugs Context 2021 26;10. Epub 2021 Mar 26.

Department of Paediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong.

Background: Despite being a common problem in childhood, functional constipation is often difficult to manage. This article provides a narrative updated review on the evaluation, diagnosis and management of childhood functional constipation.

Methods: A PubMed search was performed with Clinical Queries using the key term 'functional constipation'. Read More

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Watt matters: Safety and efficacy of using a 140-W high-powered holmium laser for enucleation of the prostate (HoLEP).

Turk J Urol 2021 Mar 1;47(2):131-136. Epub 2021 Mar 1.

Department of Urology, Okan University Hospital, Faculty of Medicine, İstanbul, Turkey.

Objective: This study aimed to assess the perioperative and the 12-month efficacy and safety of 140 W high-powered holmium laser for enucleation of the prostate (HP-HoLEP) for the treatment of benign prostatic obstruction.

Material And Methods: The data of 540 patients who underwent HoLEP by a single surgeon were analyzed retrospectively. Preoperative evaluation included a physical examination with a digital rectal examination, measurement of maximum urinary flow rate (Q), postvoid residual volume (PVR) and prostate volume by transabdominal ultrasonography, serum prostate-specific antigen (PSA), international prostate symptom score (I-PSS) and international index of erectile function-5 (IIEF-5) questionnaires, and urine analysis. Read More

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Contemporary snapshot of tumor regression grade (TRG) distribution in locally advanced rectal cancer: a cross sectional multicentric experience.

Updates Surg 2021 Apr 5. Epub 2021 Apr 5.

Department of Medical, Surgical and Health Sciences, University of Trieste, Strada di Fiume 447, Trieste, Italy.

Pre-operative chemoradiotherapy (CRT) followed by surgical resection is still the standard treatment for locally advanced low rectal cancer. Nowadays new strategies are emerging to treat patients with a complete response to pre-operative treatment, rendering the optimal management still controversial and under debate. The primary aim of this study was to obtain a snapshot of tumor regression grade (TRG) distribution after standard CRT. Read More

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Prostate carcinomas mimicking a digestive malignancy.

Rom J Morphol Embryol 2020 Jul-Sep;61(3):751-758

Discipline of Morphopathology, Department of Microscopic Morphology, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania; e-mail:

Aim: To report our experience with specific cases of prostate cancer (PC) in which patients presented digestive symptoms, cases that represent a challenge and a source of error regarding the clinical and morphological diagnosis.

Methods: The most important clinical and pathological data were collected from three patients with PC which presented symptoms and/or investigations that initially suggested a digestive malignant tumor.

Results: We identified three patients with PC where the prostate tumor was not suspected based on the clinical-imagistic data, the correct diagnosis being the prerogative of the morphological investigation: in the first case, PC was detected during the microscopic examination of the lymph nodes (LN) in the intestinal resection specimen performed for suspected rectal cancer (RC), in the second case, in which the PC was synchronous with a RC, the dominant symptomatology was gastrointestinal, and in the third case, initially, the patient presented a widely disseminated PC, with pleural and bone metastases, as well as LN metastases, and apparent peritoneal involvement. Read More

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Clinical characteristics, etiology, management and outcome of hematospermia: a systematic review.

Am J Clin Exp Urol 2021 15;9(1):1-17. Epub 2021 Feb 15.

Department of Urology, Colombo South Teaching Hospital Kalubowila, Sri Lanka.

Introduction: Hematospermia is an uncommon symptom but can cause significant anxiety among the patient and his partner. The available data on the underlying etiology, management and outcome are variable and inconsistent. This systematic review was aimed to describe the clinical characteristics, etiology, treatment and outcomes of hematospermia. Read More

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February 2021

Effect of Bacterial Vaginosis (BV)-HIV-1 Co-existence on Maternal and Infant Health: A Secondary Data Analysis.

Front Pediatr 2021 18;9:544192. Epub 2021 Mar 18.

Department of Mathematics, Physics and Computing, School of Sciences and Aerospace Studies, Moi University, Eldoret, Kenya.

The lactobacillus-rich microbiome forms a defense system against infections. Babies are born sterile and acquire their microbiome from exposure to the mothers' vaginal and rectal microbiota. Bacterial vaginosis (BV), which is characterized by a deficit of the Lactobacilli genera, may predispose women and their babies to an increased frequency of illness. Read More

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Development of a Whole-urine, Multiplexed, Next-generation RNA-sequencing Assay for Early Detection of Aggressive Prostate Cancer.

Eur Urol Oncol 2021 Mar 31. Epub 2021 Mar 31.

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Rogel Cancer Center, University of Michigan, Ann Arbor, MI, USA; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

Background: Despite biomarker development advances, early detection of aggressive prostate cancer (PCa) remains challenging. We previously developed a clinical-grade urine test (Michigan Prostate Score [MiPS]) for individualized aggressive PCa risk prediction. MiPS combines serum prostate-specific antigen (PSA), the TMPRSS2:ERG (T2:ERG) gene fusion, and PCA3 lncRNA in whole urine after digital rectal examination (DRE). Read More

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Transanal fistulectomy for postoperative persistent rectourethral fistula in patients with ARM: is simple resection enough?

BMC Surg 2021 Apr 2;21(1):179. Epub 2021 Apr 2.

Department of General Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, No. 56 Nanlishi Road, Beijing, 100045, China.

Background: Postoperative rectourethral fistula (RUF) in patients with congenital anorectal malformation (ARM) remains a challenge for paediatric surgeons, among them persistent fistula is the most common. Various techniques have been proposed, only a few reports based on different causes are available, and there is no consensus so far. This study is to evaluate the application, advantages and limitations of transanal fistulectomy approach in repairing persistent RUF in ARM patients. Read More

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Prospective Validation of Pentraxin-3 as a Novel Serum Biomarker to Predict the Risk of Prostate Cancer in Patients Scheduled for Prostate Biopsy.

Cancers (Basel) 2021 Mar 31;13(7). Epub 2021 Mar 31.

Department of Urology and Organ Transplantation, University of Foggia, 71122 Foggia, Italy.

Purpose: To test and internally validate serum Pentraxin-3 (PTX3) levels as a potential PCa biomarker to predict prostate biopsy (PBx) results.

Materials And Methods: Serum PSA and serum PTX3 were prospectively assessed in patients scheduled for PBx at our Institution due to increased serum PSA levels or abnormal digital rectal examination. Uni- and multivariable logistic regression analysis, area under the receiver operating characteristic curve (AUC), and decision curve analysis (DCA), were used to test the accuracy of serum PTX3 in predicting anyPCa and clinically significant PCa (csPCa) defined as Gleason Grade (GG) ≥ 2. Read More

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Establishment and clinical application value of an automatic diagnosis platform for rectal cancer T-staging based on a deep neural network.

Chin Med J (Engl) 2021 Feb 25;134(7):821-828. Epub 2021 Feb 25.

Department of General Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Background: Colorectal cancer is harmful to the patient's life. The treatment of patients is determined by accurate preoperative staging. Magnetic resonance imaging (MRI) played an important role in the preoperative examination of patients with rectal cancer, and artificial intelligence (AI) in the learning of images made significant achievements in recent years. Read More

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February 2021

Endoscopic Feature and Response Reproducibility in Tumor Assessment after Neoadjuvant Therapy for Rectal Adenocarcinoma.

Ann Surg Oncol 2021 Apr 1. Epub 2021 Apr 1.

Department of Surgery, Colorectal Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.

Background: The watch-and-wait approach may be safe for selected rectal cancer patients who achieve a complete clinical response after neoadjuvant treatment. Endoscopic examination is critical in determining completeness of tumor response but has not been systematically studied.

Methods: Two cross-sectional surveys, each containing endoscopic photos of rectal cancers treated with neoadjuvant therapy, were distributed to surgeons. Read More

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Presacral Tumor: Insights From a Decade's Experience of This Rare and Diverse Disease.

Zeyu Li Min Lu

Front Oncol 2021 16;11:639028. Epub 2021 Mar 16.

Department of Colorectal Surgery, First Affiliated Hospital of China Medical University, Shenyang, China.

Background: Presacral tumors are a group of rare and heterogeneous tumors that arise from the potential presacral space between the rectum and sacrum. The low occurrence and diverse origins make the diagnosis and treatment of these tumors a challenge. The aim of the study was to retrospectively review patient demographics and to identify advantages and disadvantages in the diagnosis and treatment of these tumors. Read More

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Lower gastrointestinal bleeding in a patient receiving sevelamer: Case report.

SAGE Open Med Case Rep 2021 15;9:2050313X211000488. Epub 2021 Mar 15.

Department of Nephrology, Jeroen Bosch Ziekenhuis, 's-Hertogenbosch, The Netherlands.

Phosphate binders such as sevelamer are widely used in patients with chronic kidney disease to lower serum phosphate levels. We present a case of a 67-year-old woman with lower gastrointestinal bleeding after 9 days of using sevelamer carbonate (Renvela). Sigmoidoscopy revealed multiple deep ulcers (diameter 10-15 mm) and mucosal oedema. Read More

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Clinical characteristics, medical service utilization, and expenditure for colorectal cancer in China, 2005 to 2014: Overall design and results from a multicenter retrospective epidemiologic survey.

Cancer 2021 Mar 30. Epub 2021 Mar 30.

Department of Thoracic Surgery, NCC/NCRCC/Cancer Hospital, CAMS & PUMC, Beijing, China.

Background: Colorectal cancer (CRC) is the third most common cancer in China, however, publicly available, descriptive information on the clinical epidemiology of CRC is limited.

Methods: Patients diagnosed with primary CRC during 2005 through 2014 were sampled from 13 tertiary hospitals in 9 provinces across China. Data related to sociodemographic characteristics, the use of diagnostic technology, treatment adoption, and expenditure were extracted from individual medical records. Read More

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Prostate cancer early detection among primary care physicians in Mexico: A cross-sectional study.

Cir Cir 2021 ;89(2):163-169

Virology Lab, Centro de Investigaciones Regionales, Universidad Autónoma de Yucatán. Yucatán, Mexico.

Aim: This study aims to assess primary care physicians (PCPs) knowledge and skills regarding prostate cancer early detection (PCa-ED).

Materials And Methods: A survey about knowledge and skills of PCa-ED was delivered to PCP. Logistic regression analysis was conducted for the propensity of PCP to test prostatic specific antigen (PSA) on asymptomatic men. Read More

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January 2021

Successful Surgical and Medical Management of a Pararectal Abscess in a Horse.

J Equine Vet Sci 2021 Apr 13;99:103387. Epub 2021 Jan 13.

Department of Veterinary Medicine, Veterinary Teaching Hospital, University of Perugia, Perugia, Italy; Sport Horse Research Centre, University of Perugia, Perugia, Italy.

Pararectal abscesses are life-threatening conditions that can rupture and cause septic peritonitis. The objective of this case report is to describe aggressive treatment of a pararectal abscess to allow a quick return to competitions. A 14-year-old pony was admitted to the Veterinary Teaching Hospital (VTH) of the University of Perugia because of a suspected intra-abdominal mass. Read More

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Safety and Efficacy of High-Powered Holmium Laser Enucleation of the Prostate within 1-3 Weeks Following Prostate Biopsy.

Urol Int 2021 Mar 29:1-6. Epub 2021 Mar 29.

Department of Urology, Faculty of Medicine, Okan University Hospital, Istanbul, Turkey.

Purpose: We aim to document the feasibility, perioperative safety, and the 12-month efficacy of holmium laser enucleation of the prostate (HoLEP) within 1-3 weeks following transrectal ultrasound (TRUS)-guided prostate biopsy.

Methods: Data of the patients who underwent HoLEP following TRUS-guided prostate biopsy between March 2017 and July 2020 were analyzed retrospectively. Patients were divided into 2 groups: group 1 had undergone HoLEP in the early period after TRUS-guided prostate biopsy, while group 2 patients were biopsy-naive ("control group"). Read More

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Biparametric MRI prior to Radical Radiation Therapy for Prostate Cancer in a Caribbean Population: Implications for Risk Group Stratification and Treatment.

Radiol Imaging Cancer 2020 Jul 31;2(4):e200007. Epub 2020 Jul 31.

Departments of Clinical Medical Sciences (M.A.G., D.N.) and Paraclinical Sciences (S.M.), Faculty of Medical Sciences, Eric Williams Medical Sciences Complex, Building 39, First Floor Uriah Butler Highway, Champ Fleurs, University of the West Indies, St Augustine Campus, St Augustine, Trinidad; and Departments of Urology (A.P.R., K.S.) and Radiology (C.M.G., M.D.M., R.B.), San Fernando General Hospital, Paradise Pasture Independence Avenue, San Fernando, Trinidad.

Purpose: To assess risk-group migration and subsequent management change following biparametric MRI using a risk-stratified approach in a group of Caribbean men with prostate adenocarcinoma being offered external beam radiation therapy (EBRT).

Materials And Methods: This retrospective study assessed the biparametric MRI findings in men who opted for EBRT from January 2018 to June 2019 ( = 79; mean age, 67.9 years ± 6. Read More

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Endometriosis of the rectosigmoid colon mimicking gastrointestinal stromal tumor.

Turk J Surg 2020 Dec 29;36(4):409-412. Epub 2020 Dec 29.

Clinic of Radiology, Ankara Umut Hospital, Ankara, Turkey.

Endometriosis is defined as the growth of functional endometriotic gland and stroma outside the uterine cavity. Although it is common in women of reproductive age, extragenital endometriosis is considerably rare. Due to its frequent localization at the rectosigmoid junction in the gastrointestinal system, endometriosis may manifest with abdominal pain, constipation, and rectal bleeding. Read More

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December 2020

Comparison of the effectiveness of two treatment modalities for chronic anal fissure: Botox versus sphincterotomy.

Turk J Surg 2020 Sep 28;36(3):264-270. Epub 2020 Sep 28.

Sisli Hamidiye Etfal Training And Research Hospital, General Surgery, Istanbul, Turkey.

Objectives: Anal fissure is a common health problem that affects the quality of life of young patients. The aim of our study was to benchmark results of lateral internal sphincterotomy (LIS) and botulinum toxin injection in the treatment of chronic anal fissure.

Material And Methods: This multi-center, retrospective study used data from 135 chronic anal fissure patients. Read More

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September 2020

Body size throughout the life-course and incident benign prostatic hyperplasia-related outcomes and nocturia.

BMC Urol 2021 Mar 27;21(1):47. Epub 2021 Mar 27.

Division of Public Health Sciences, Department of Surgery, Washington University in St. Louis School of Medicine, 660 S. Euclid Ave., Campus Box 8100, St. Louis, MO, 63110, USA.

Background: Existing evidence suggests that there is an association between body size and prevalent Benign Prostatic Hyperplasia (BPH)-related outcomes and nocturia. However, there is limited evidence on the association between body size throughout the life-course and incident BPH-related outcomes.

Methods: Our study population consisted of men without histories of prostate cancer, BPH-related outcomes, or nocturia in the intervention arm of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial (PLCO) (n = 4710). Read More

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[Long-term results of surgical correction of H-type fistula in girls with a normal anus].

Khirurgiia (Mosk) 2021 (4):39-45

Pirogov Russian National Research Medical University, Moscow, Russia.

Objective: To evaluate the long-term results of surgical correction of H-type fistula in girls with a normal anus.

Material And Methods: There were 7 patients with rectovestibular fistula and 3 patients with rectovaginal fistula with a normal anus were observed from 2014 to 2019 in the Surgical Department No. 1 of the Russian Children's Clinical Hospital. Read More

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January 2021

Detection limits of significant prostate cancer using multiparametric MR and digital rectal examination in men with low serum PSA: Up-date of the Italian Society of Integrated Diagnostic in Urology.

Arch Ital Urol Androl 2021 Mar 22;93(1):92-100. Epub 2021 Mar 22.

Division of Urology, School of Medicine, Università Politecnica delle Marche, Ancona.

Reasons why significant prostate cancer is still missed in early stage were investigated at the 22nd National SIEUN (Italian Society of integrated diagnostic in Urology, Andrology, Nephrology) congress took place from 30th November to 1st December 2020, in virtual modality. Even if multiparametric magnetic resonance (MR) has been introduced in the clinical practice several, limitations are emerging in patient with regular digital rectal examination (DRE) and serum prostate specific antigen (PSA) levels approaching the normal limits. The present paper summarizes highlights observed in those cases where significant prostate cancer may be missed by PSA or imaging and DRE. Read More

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Is there a PSA cut-off value indicating incidental prostate cancer in patients undergoing surgery for benign prostatic hyperplasia?

Arch Ital Urol Androl 2021 Mar 18;93(1):31-34. Epub 2021 Mar 18.

Department of Urology, University of Health Sciences, Ankara City Hospital, Ankara.

Aim: To investigate incidental prostate cancer (IPCa) rate and to determine prostate specific antigen (PSA) cut-off value indicating PCa in patients who underwent surgery by being diagnosed with benign prostatic hyperplasia (BPH) clinically or by standard prostate biopsy.

Methods: Data of 317 patients, who underwent transurethral resection of the prostate (TURP) or open prostatectomy (OP) with pre-diagnosis of BPH, were evaluated retrospectively. The examined parameters included patients' demographics, preoperative serum PSA values, digital rectal examination (DRE) findings, surgical method, histopathological findings and Gleason Scores. Read More

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A case of early rectal carcinoma with submucosal tumor-like morphology.

Clin J Gastroenterol 2021 Mar 22. Epub 2021 Mar 22.

Department of Gastroenterology and Hepatology, Tokyo Medical University Hospital, 6-7-1, Nishi-shinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan.

Submucosal tumor (SMT)-like colorectal cancer is relatively rare. The patient was a 59-year-old man who underwent colonoscopy after a positive fecal occult blood test. Colonoscopy showed a protruded lesion of 10 mm in the lower rectum. Read More

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Surgical treatment of deep endometriosis with adenomyosis externa: a challenging case in an infertile woman.

Fertil Steril 2021 Apr 6;115(4):1084-1086. Epub 2021 Mar 6.

Department of Radiology, Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy.

Objective: To describe the management and the fertility-enhancing potential of surgery in an infertile patient with deep-infiltrating endometriosis and adenomyosis externa.

Design: Video case report.

Setting: Minimally invasive and robotic gynecologic surgery unit of a university hospital. Read More

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Transanal vs laparoscopic total mesorectal excision for rectal cancer: a multicenter randomized phase III clinical trial (TaLaR trial) protocol.

Gastroenterol Rep (Oxf) 2021 Jan 14;9(1):71-76. Epub 2020 Dec 14.

Department of Colorectal Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, P. R. China.

Background: Total mesorectum excision (TME) is considered the standard surgical procedure for rectal-cancer treatment. Transanal TME (taTME) is a new procedure to treat low rectal cancer. Some published studies have proven that taTME can provide a better-quality resected specimen in low-rectal-cancer patients in comparison to the transabdominal procedure, yet long-term outcomes must be investigated. Read More

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January 2021

Levator ani and puborectalis muscle rupture: diagnosis and repair for perineal instability.

Tech Coloproctol 2021 Mar 20. Epub 2021 Mar 20.

Proctology Unit and Pelvic Floor Unit, Division of Digestive Surgery, Department of Surgery, Geneva University Hospitals and Medical School, 4 rue Gabrielle-Perret-Gentil, 1211, Geneva, Switzerland.

Background: Puborectalis muscle rupture usually arises from peri-partum perineal trauma and may result in anterior, middle compartment prolapses, posterior compartment prolapse which includes rectocele and rectal prolapse, with or without associated anal sphincter damage. Patients with puborectalis muscle and levator ani rupture may present some form of incontinence or evacuation disorder, sexual dysfunction or pelvic organ descent. However, the literature on this subject is scarce. Read More

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