84,554 results match your criteria records reviewed

Cardiotocograph (CTG) changes and maternal and neonatal outcomes in chorioamnionitis and/or funisitis confirmed on histopathology.

Eur J Obstet Gynecol Reprod Biol 2021 Mar 30;260:183-188. Epub 2021 Mar 30.

Global Academy of Medical Education & Training, London & Consultant Intrapartum Care Advisor, Basildon University Hospital, Mid and South Essex NHS Foundation Trust, Essex, UK. Electronic address:

Objective: To assess the cardiotocographic changes and maternal and neonatal outcomes in cases of chorioamnionitis and or funisitis confirmed on histopathology.

Study Design: A retrospective analysis of histopathology reports confirming chorioamnionitis and/or funisitis was carried out from 2014 to 2020 in a single centre. The preterm births (<37 weeks) were excluded. Read More

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The effects of antibiotics on the efficacy of immune checkpoint inhibitors in patients with non-small-cell lung cancer differ based on PD-L1 expression.

Eur J Cancer 2021 Apr 7;149:73-81. Epub 2021 Apr 7.

Department of Allergy and Respiratory Medicine, Okayama University Hospital, Japan.

Background: Immune checkpoint inhibitors (ICIs) are essential for treatment of various malignancies, including non-small-cell lung cancer (NSCLC). Recently, several studies have shown that the gut microbiome plays an important role in ICI treatment of solid cancers, and antibiotic (ATB) use had a negative impact on the outcomes of ICI treatment via dysbiosis in the gut. However, whether this is applicable to NSCLC remains unclear. Read More

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Papillary thyroid microcarcinomas that metastasize to lymph nodes.

Am J Otolaryngol 2021 Mar 31;42(5):103023. Epub 2021 Mar 31.

Department of Endocrinology and Metabolism, Ankara Yıldırım Beyazıt University Faculty of Medicine, Ankara, Turkey.

Purpose: We aimed to determine clinicopathological features that can predict lymph node metastasis (LNM) in papillary thyroid microcarcinomas (PTMC).

Methods: Medical records of 872 patients with papillary thyroid cancer >1 cm (PTC > 1 cm) and 1184 patients with papillary thyroid microcancer (PTMC) (≤1 cm) were reviewed retrospectively. Demographical, clinical and histopathological features of (PTC > 1 cm) and PTMC were compared. Read More

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Risk factors for incorrect surgical count during surgery: An observational study.

Int J Nurs Pract 2021 Apr 10:e12942. Epub 2021 Apr 10.

Department of Surgery, The First Affiliated Hospital of Soochow University, Suzhou City, China.

Background: Incorrect surgical counts are closely related to retained surgical items, which pose a threat to patients. However, the risk factors for incorrect surgical counts have not been identified yet.

Aim: To identify the risk factors associated with incorrect surgical counts during surgery in a tertiary hospital. Read More

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Computed tomographic features of coronavirus disease-2019 (COVID-19) pneumonia in three groups of Iranian patients: A single center study.

Radiologia 2021 Mar 14. Epub 2021 Mar 14.

Centro de Investigación de Gastroenterología y Enfermedades Hepáticas, Instituto de Investigación de Gastroenterología y Enfermedades Hepáticas, Universidad de Ciencias Médicas Shahid Beheshti, Teherán, Irán.

Introduction And Objectives: The pivotal role of chest computed tomographic (CT) to diagnosis and prognosis coronavirus disease-2019 (COVID-19) is still an open field to be explored. This study was conducted to assess the CT features in confirmed cases with COVID-19.

Materials And Methods: Retrospectively, initial chest CT data of 363 confirmed cases with COVID-19 were reviewed. Read More

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Ultrasound features of medullary thyroid cancer as predictors of biological behavior.

Cancer Imaging 2021 Apr 9;21(1):33. Epub 2021 Apr 9.

Departments of Thyroid and Neck Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin, 300060, P. R. China.

Background: Medullary thyroid cancer (MTC) has more aggressive behavior and poor prognosis. Ultrasound (US) has facilitated the qualitative diagnosis of thyroid nodules, however, some MTC may be diagnosed as a benign nodule on ultrasound because ultrasound features of malignancy are lacking. The aim of the study was to investigate the association between ultrasound features and biological behavior of MTC. Read More

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Restarting cataract surgery during the COVID-19 pandemic; a prospective study analysing 30 day outcomes after elective cataract surgery in the United Kingdom.

BMC Ophthalmol 2021 Apr 9;21(1):167. Epub 2021 Apr 9.

Ophthalmology Department, Ashford & St Peter's Hospitals NHS Foundation Trust, Ashford, UK.

Background: Cataract is a significant cause of preventable blindness in the United Kingdom and worldwide. Prior to the COVID-19 pandemic, cataract surgery was the most commonly performed operation by the National Health Service in the United Kingdom. The aim of this study is to evaluate the safety of elective cataract surgery performed in the United Kingdom in a COVID-19 free hospital during the COVID-19 pandemic. Read More

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Effects of sirolimus in the treatment of unresectable infantile hemangioma and vascular malformations in children: A single-center experience.

J Vasc Surg Venous Lymphat Disord 2021 Apr 6. Epub 2021 Apr 6.

Department of Pediatric Surgery, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Korea.

Objective: Recently, sirolimus has emerged as a safe and effective treatment modality for unresectable vascular lesions. In this study, we investigated the effectiveness and safety of sirolimus based an early experience with patients with unresectable vascular anomalies.

Methods: Medical records and radiological images of all patients with unresectable vascular anomalies treated with sirolimus at our center between January 2018 and November 2019 were retrospectively reviewed. Read More

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Extracerebellar Signs and Symptoms in 117 Korean Patients with Early-Stage Spinocerebellar Ataxia.

J Clin Neurol 2021 Apr;17(2):242-248

Department of Neurology, Samsung Medical Center, Seoul, Korea.

Background And Purpose: Spinocerebellar ataxias (SCAs) are the most common form of hereditary ataxias. Extracerebellar signs have been well described and are helpful in differentiating the SCA subtypes. However, there are few reports on the early-stage extracerebellar signs in various SCA subtypes. Read More

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Patterns of Recurrence of Phonotraumatic Vocal Fold Lesions Suggest Distinct Mechanisms of Injury.

Laryngoscope 2021 Apr 9. Epub 2021 Apr 9.

The Sean Parker Institute for the Voice, Department of Otolaryngology-Head & Neck Surgery, Weill Cornell Medicine, New York, New York, USA.

Objectives/hypothesis: To examine patterns of recurrence of benign phonotraumatic vocal fold lesions over time for insights into pathophysiology.

Study Design: Case series with mathematical modeling.

Methods: Medical records and stroboscopic exams of adults who underwent microlaryngoscopic resection of phonotraumatic vocal fold lesions over a 13-year period were reviewed for time to recurrence after surgery. Read More

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Significance of preoperative systemic immune-inflammation (SII) in predicting postoperative systemic inflammatory response syndrome after percutaneous nephrolithotomy.

Urolithiasis 2021 Apr 9. Epub 2021 Apr 9.

Department of Urology, Shaoxing People's Hospital, Shaoxing, 312000, China.

There is evidence that inflammation response biomarkers are positivity associated with bacteremia and urosepsis. The objective of this study was to investigate the value of preoperative systemic immune-inflammation (SII) in predicting systemic inflammatory response syndrome (SIRS) after percutaneous nephrolithotomy (PCNL). Records from 365 consecutive patients who previously received standard PCNL for kidney stones were retrospectively reviewed. Read More

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Induction Immunosuppressive Therapy for Kidney Transplant in Elderly Recipients: A Single-Center Experience.

Exp Clin Transplant 2021 Apr;19(4):297-303

From the Medical City Fort Worth Transplant Institute, Fort Worth, Texas, USA.

Objectives: The number of elderly kidney transplant recipients is increasing, and age-tailored induction immunosuppression regimens are needed. We compared safety and efficacy of basiliximab versus thymoglobulin at various dosages.

Materials And Methods: Of 590 kidney transplants at our center from 2012 to 2019, 119 (20. Read More

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Infiltrative Tumor Borders in Colorectal Liver Metastasis: Should We Enlarge Margin Size?

Ann Surg Oncol 2021 Apr 8. Epub 2021 Apr 8.

Digestive Surgery Division, Liver Surgery Unit, Department of Gastroenterology, Hospital das Clinicas, University of Sao Paulo School of Medicine, São Paulo, SP, Brazil.

Background: Surgery is the only potentially curative treatment for colorectal cancer liver metastases (CRLMs). Despite an improvement in results following resection, recurrence rates remain high. Many histopathological features have been reported as prognostic factors. Read More

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Kidney function in patients with primary distal renal tubular acidosis.

Pediatr Nephrol 2021 Apr 8. Epub 2021 Apr 8.

Hospital Universitario Central de Asturias, Avd. Roma SN, 33011, Oviedo, Spain.

Background: Recent reports indicate that chronic reduction of glomerular filtration rate (GFR) is common in patients with distal renal tubular acidosis (DRTA). Factors responsible for decreased GFR need clarification.

Methods: We reviewed records of 25 patients with genetically confirmed DRTA included in the RenalTube database. Read More

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Viral lower respiratory tract infections-strict admission guidelines for young children can safely reduce admissions.

Eur J Pediatr 2021 Apr 8. Epub 2021 Apr 8.

Department of Pediatric and Adolescent Medicine, Akershus University Hospital, Sykehusveien 25, 1478, Nordbyhagen, Norway.

Viral lower respiratory tract infection (VLRTI) is the most common cause of hospital admission among small children in high-income countries. Guidelines to identify children in need of admission are lacking in the literature. In December 2012, our hospital introduced strict guidelines for admission. Read More

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Suspecting Intussusception and Recurrence Risk Stratification Using Clinical Data and Plain Abdominal Radiographs.

Pediatr Gastroenterol Hepatol Nutr 2021 Mar 4;24(2):135-144. Epub 2021 Mar 4.

Department of Pediatrics, Korea University Ansan Hospital, Ansan, Korea.

Purpose: Although ultrasonography is the gold standard of diagnosing intussusception, plain abdomen radiograph (AXR) is often used to make differential diagnosis for pediatric patients with abdominal pain. In intussusception patients, we aimed to analyze the AXR and clinical data to determine the characteristics of early AXR findings associated with diagnosis of intussusception and recurrence after reduction.

Methods: Between January 2011 and June 2018, 446 patients diagnosed with intussusception based on International Classification of Diseases-10 code of K56. Read More

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Comparison of Clinical Characteristics According to the Existence of Secondary Appendicitis in Pediatric Acute Enterocolitis: A Single Center Study.

So Yoon Choi

Pediatr Gastroenterol Hepatol Nutr 2021 Mar 4;24(2):127-134. Epub 2021 Mar 4.

Department of Pediatrics, Kosin University College of Medicine, Kosin University Gospel Hospital, Busan, Korea.

Purpose: In patients with acute enterocolitis, radiologic findings are sometimes accompanied by secondary inflammation of the appendix. The purpose of this study was to evaluate the clinical features of acute enterocolitis with secondary inflammation of the appendix.

Methods: Medical records from patients who underwent abdominal ultrasonography or computed tomography (CT) among those admitted for acute enterocolitis were retrospectively reviewed. Read More

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Persistent Shoulder Pain After Anterior Cervical Discectomy and Fusion (ACDF): Another Dual Pathology.

Cureus 2021 Mar 5;13(3):e13709. Epub 2021 Mar 5.

Orthopedics, Dr. Ziauddin Hospital, Kemari Campus, Karachi, PAK.

Purpose It is often difficult for the clinician to isolate the etiology of pain occurring either in the neck or shoulder because of the reason that neck pain can refer to the shoulder and vice versa. Concordance research has found that around one in 10 patients who were referred for cervical radiculopathy had comorbid shoulder pathology. The goal of this research is to analyze and correlate risk factors for persistent shoulder pain (non-dermatomal) following cervical spine surgery. Read More

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Associations of Skilled Nursing Facility Quality Ratings With 30-Day Rehospitalizations and Emergency Department Visits.

Ann Longterm Care 2020 Mar 6;28(1):e11-e17. Epub 2019 Dec 6.

Division of Community Internal Medicine, Mayo Clinic, Rochester, Minnesota.

Skilled nursing facilities (SNFs) increasingly provide care to patients after hospitalization. The Centers for Medicare & Medicaid Services reports ratings for SNFs for overall quality, staffing, health inspections, and clinical quality measures. However, the relationship between these ratings and patient outcomes remains unclear. Read More

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Non-responsive celiac disease in children on a gluten free diet.

World J Gastroenterol 2021 Apr;27(13):1311-1320

Division of Gastroenterology, Hepatology and Nutrition, Boston Children's Hospital, Boston, MA 02115, United States.

Background: Non-responsive celiac disease (NRCD) is defined as the persistence of symptoms in individuals with celiac disease (CeD) despite being on a gluten-free diet (GFD). There is scant literature about NRCD in the pediatric population.

Aim: To determine the incidence, clinical characteristics and underlying causes of NRCD in children. Read More

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Assessing the appropriateness of the management of gastro-oesophageal reflux in Australian children: a population-based sample survey.

Sci Rep 2021 Apr 8;11(1):7744. Epub 2021 Apr 8.

Centre for Healthcare Resilience and Implementation Science, Australian Institute of Health Innovation, Macquarie University, Level 6, 75 Talavera Road, Sydney, NSW, 2109, Australia.

Gastro-oesophageal reflux (GOR) is a common physiological state in infants and young children, with gastro-oesophageal reflux disease (GORD) its pathological manifestation. Management of GOR/GORD requires elimination of possible underlying causes, parental reassurance, modification of feeding and symptom mitigation, monitoring, and referral to paediatricians if warning signs are present. Published clinical practice guidelines (CPGs) seek to support clinicians and improve management. Read More

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Subglottic Post-Extubation Upper Airway Obstruction Is Associated With Long-Term Airway Morbidity in Children.

Pediatr Crit Care Med 2021 Apr 8. Epub 2021 Apr 8.

Department of Pediatrics, Division of Pediatric Critical Care Medicine, Cedars-Sinai Medical Center, Los Angeles, CA. Department of Anesthesiology Critical Care Medicine, Keck School of Medicine of University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA. Department of Pediatrics, Keck School of Medicine of University of Southern California, Children's Hospital Los Angeles, Los Angeles, CA.

Objectives: Post-extubation upper airway obstruction is the most common cause of extubation failure in children, but there are few data regarding long-term morbidity. We aim to describe the frequency of long-term airway sequelae in intubated children and determine the association with post-extubation upper airway obstruction.

Design: Retrospective, post hoc analysis of previously identified prospective cohort of children in the pediatric/cardiothoracic ICU at Children's Hospital Los Angeles from July 2012 to April 2015. Read More

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Utilization of a Newly Designed Asymmetric Dorsal Gull Wing Flap for the Treatment of Postoperative Web Creep After Syndactyly Surgery.

Ann Plast Surg 2021 Apr 5. Epub 2021 Apr 5.

From the Department of Burns and Plastic Surgery, Ministry of Education Key Laboratory of Child Development and Disorders, National Clinical Research Center for Child Health and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders; Chongqing Key Laboratory of Pediatrics, Children's Hospital of Chongqing Medical University, Chongqing, P.R. China.

Background: Web creep is the most common long-term complication requiring revision after syndactyly surgery; however, few methods have been reported. The aim of this study was to introduce a newly designed asymmetric dorsal gull wing flap to reconstruct web for the postoperative web creep.

Methods: A retrospective analysis was performed for 20 patients from January 2016 to May 2019. Read More

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Tubal factor infertility, in vitro fertilization, and racial disparities: a retrospective cohort in two US clinics.

Sex Transm Dis 2021 Apr 1. Epub 2021 Apr 1.

Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta GA University of Pittsburgh School of Medicine and Magee-Womens Research Institute, Pittsburgh, PA Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta GA University of Pittsburgh Graduate School of Public Health Department of Epidemiology and Magee-Womens Research Institute, Pittsburgh, PA Alabama Fertility Specialists, Birmingham, AL Department of Medicine, University of Alabama at Birmingham, Birmingham, AL.

Background: Nearly 14% of US women report any lifetime infertility which is associated with healthcare costs and psychosocial consequences. Tubal factor infertility (TFI) often occurs as a result of sexually transmitted diseases and subsequent pelvic inflammatory disease. We sought to evaluate for and describe potential racial disparities in TFI and in vitro fertilization (IVF) prevalence. Read More

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External fixation with bone cement implantation for open calcaneal fractures: A case series.

Foot Ankle Surg 2021 Mar 31. Epub 2021 Mar 31.

Department of Orthopaedics, Drum Tower Hospital, Medical School of Nanjing University, No. 321 Zhongshan Road, Nanjing, China.

Objective: The purpose of this study was to retrospectively evaluate patients who had open reduction, external fixation and bone cement implantation of open calcaneal fractures.

Methods: The records of 14 patients with open calcaneus fractures from January 2015 to January 2019 were reviewed retrospectively. Clinical evaluations consisting of AOFAS, MFS and EQ-5D VAS scores and radiological evaluations consisting of the height, width and length of the calcaneus as well as Bohler's and Gissane angle performed at 3 months, 1 year and the last follow-up postoperatively. Read More

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Characteristics of a COVID-19 confirmed case series in primary care (COVID-19-PC project): a cross-sectional study.

BMC Fam Pract 2021 Apr 8;22(1):66. Epub 2021 Apr 8.

Primary Health Care Centre General Ricardos, Calle General Ricardos 131, 28019, Madrid, Spain.

Background: To estimate the prevalence of symptoms and signs related to a COVID-19 case series confirmed by polymerase chain reaction (PCR) for SARS-CoV-2. Risk factors and the associated use of health services will also be analysed.

Methods: Observational, descriptive, retrospective case series study. Read More

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Real-world effectiveness of lenvatinib monotherapy among unresectable hepatocellular carcinoma patients in the USA.

Future Oncol 2021 Apr 9. Epub 2021 Apr 9.

Global Real World Evidence & US HEOR, Eisai, Inc., Woodcliff Lake, NJ 07677, USA.

This study evaluated the effectiveness of lenvatinib monotherapy for first-line treatment of unresectable hepatocellular carcinoma (uHCC) in a real-world setting. This retrospective cohort study included patients who initiated lenvatinib monotherapy as first-line treatment for uHCC (n = 233). Clinical outcomes included provider-reported best response, progression-free survival (PFS) and overall survival (OS). Read More

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Perioperative pulmonary aspiration and regurgitation without aspiration in adults: a retrospective observational study of 166,491 anesthesia records.

Ann Palliat Med 2021 Mar 23. Epub 2021 Mar 23.

Department of Anesthesiology and Perioperative Medicine, First Affiliated Hospital with Nanjing Medical University, Nanjing, China.

Background: Pulmonary aspiration (PA) of gastric contents is a rare but serious perioperative complication. Recent studies focused on pediatric patients, but over a decade has passed since the latest incidence and outcome in adult population have been reported. Patients who experienced regurgitation without aspiration were rarely mentioned. Read More

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A comparative study of functioning and non-functioning pituitary adenomas.

Medicine (Baltimore) 2021 Apr;100(14):e25306

Department of Ophthalmology, Peking University People's Hospital, Eye Diseases and Optometry Institute, Beijing Key Laboratory of Diagnosis and Therapy of Retinal and Choroid Diseases, College of Optometry, Peking University Health Science Center, Xi Cheng District.

Abstract: Pituitary tumors commonly cause visual impairment and the degree of impairment can depend on the size, location, and type of the tumor. However, no studies have been made regarding the differences caused by functioning pituitary adenoma (FPA) and non-functioning pituitary adenoma (NFPA). We aimed to investigate the relationship between clinical characteristics and visual impairment in patients with FPA and NFPA. Read More

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