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Taxonomic updates for the genus Gyrovirus (family Anelloviridae): recognition of several new members and establishment of species demarcation criteria.

Arch Virol 2021 Aug 4. Epub 2021 Aug 4.

The Biodesign Center for Fundamental and Applied Microbiomics, Center for Evolution and Medicine, School of Life Sciences, Arizona State University, 1001 S. McAllister Ave, Tempe, AZ, 85287-5001, USA.

The genus Gyrovirus was assigned to the family Anelloviridae in 2017 with only one recognized species, Chicken anemia virus. Over the last decade, many diverse viruses related to chicken anemia virus have been identified but not classified. Here, we provide a framework for the classification of new species in the genus Gyrovirus and communicate the establishment of nine new species. Read More

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An Iterative Co-Training Transductive Framework for Zero Shot Learning.

IEEE Trans Image Process 2021 Aug 3;PP. Epub 2021 Aug 3.

In zero-shot learning (ZSL) community, it is generally recognized that transductive learning performs better than inductive one as the unseen-class samples are also used in its training stage. How to generate pseudo labels for unseen-class samples and how to use such usually noisy pseudo labels are two critical issues in transductive learning. In this work, we introduce an iterative co-training framework which contains two different base ZSL models and an exchanging module. Read More

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Artificial Intelligence-Aided Recognition of Pathological Characteristics and Subtype Classification of Superficial Perivascular Dermatitis.

Front Med (Lausanne) 2021 16;8:696305. Epub 2021 Jul 16.

Department of Dermatology, Beijing Hospital, National Center of Gerontology, Beijing, China.

Superficial perivascular dermatitis, an important type of inflammatory dermatosis, comprises various skin diseases, which are difficult to distinguish by clinical manifestations and need pathological imaging observation. Coupled with its complex pathological characteristics, the subtype classification depends to a great extent on dermatopathologists. There is an urgent need to develop an efficient approach to recognize the pathological characteristics and classify the subtypes of superficial perivascular dermatitis. Read More

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Translation and cross-cultural adaptation of the Clinical Care Classification system.

Int J Med Inform 2021 Jul 16;153:104534. Epub 2021 Jul 16.

Saint Camillus International University of Health Sciences, Via di Sant'Alessandro 8, Rome 00131, Italy.

Introduction: The Clinical Care Classification (CCC) system is one of the standard nursing terminologies recognized by the American Nurses Association, developed to describe nursing care through electronic documentation in different healthcare settings. The translation of the CCC system into languages other than English is useful to promote its widespread use in different countries and to provide the standard nursing data necessary for interoperable health information exchange. The aim of this study was to translate the CCC system from English to Italian and to test its clinical validity. Read More

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Family Genomoviridae: 2021 taxonomy update.

Arch Virol 2021 Jul 31. Epub 2021 Jul 31.

Archaeal Virology Unit, Institut Pasteur, Paris, France.

The family Genomoviridae (phylum Cressdnaviricota, class Repensiviricetes, order Geplafuvirales) includes viruses with circular single-stranded DNA genomes encoding two proteins, the capsid protein and the rolling-circle replication initiation protein. The genomes of the vast majority of members in this family have been sequenced directly from diverse environmental or animal- and plant-associated samples, but two genomoviruses have been identified infecting fungi. Since the last taxonomic update of the Genomoviridae, a number of new members of this family have been sequenced. Read More

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Couple oriented counselling improves male partner involvement in sexual and reproductive health of a couple: Evidence from the ANRS PRENAHTEST randomized trial.

PLoS One 2021 30;16(7):e0255330. Epub 2021 Jul 30.

Centre Pasteur Cameroon, Epidemiology and Public Health Service, Yaounde, Cameroon.

Background: Male partner involvement (MPI) has been recognized as a priority area to be strengthened in Prevention of Mother to Child Transmission (PMTCT) of HIV. We explored the impact of Couple Oriented Counselling (COC) in MPI in sexual and reproductive health and associated factors.

Method: From February 2009 to October 2011, pregnant women were enrolled at their first antenatal care visit (ANC-1) and followed up until 6 months after delivery in the Mother and Child Center of the Chantal Biya Foundation within the randomized prenahtest multicentric trial. Read More

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Giant Cell Urothelial Carcinoma of Bladder.

Case Rep Urol 2021 15;2021:8021947. Epub 2021 Jul 15.

Department of Anatomy, Faculty of Medicine, University of Colombo, Sri Lanka.

Giant cell urothelial carcinoma is a rare variant of bladder cancer recognized by the current World Health Organization classification of urologic tumours. It is an aggressive tumour with a poor prognosis that usually presents at an advanced stage. It is characterized histologically by pleomorphic giant cells. Read More

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Persistent monocular visual loss in migraine patients.

Acta Neurol Belg 2021 Jul 29. Epub 2021 Jul 29.

Neurology Department, Hospital da Luz de Lisboa, Avenida Lusíada nº100, 1500-650, Lisboa, Portugal.

The relationship between migraine and vision is complex. Besides migraine aura status and persistent visual aura without infarction, recognized by International Headaches Classification 3, cases of persistent monocular alterations have been described in migraineurs. To discuss the role of migraine as a risk factor for persistent monocular visual loss. Read More

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Interactions between staphylococcal enterotoxins A and D and superantigen-like proteins 1 and 5 for predicting methicillin and multidrug resistance profiles among Staphylococcus aureus ocular isolates.

PLoS One 2021 28;16(7):e0254519. Epub 2021 Jul 28.

Department of Ophthalmology, Ocular Microbiology Laboratory, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, United States of America.

Background: Methicillin-resistant Staphylococcus aureus (MRSA) and multidrug-resistant (MDR) S. aureus strains are well recognized as posing substantial problems in treating ocular infections. S. Read More

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Automatic anatomical classification of colonoscopic images using deep convolutional neural networks.

Gastroenterol Rep (Oxf) 2021 Jun 7;9(3):226-233. Epub 2020 Dec 7.

Tada Tomohiro Institute of Gastroenterology and Proctology, Saitama, Japan.

Background: A colonoscopy can detect colorectal diseases, including cancers, polyps, and inflammatory bowel diseases. A computer-aided diagnosis (CAD) system using deep convolutional neural networks (CNNs) that can recognize anatomical locations during a colonoscopy could efficiently assist practitioners. We aimed to construct a CAD system using a CNN to distinguish colorectal images from parts of the cecum, ascending colon, transverse colon, descending colon, sigmoid colon, and rectum. Read More

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Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer.

Int J Cancer 2021 Jul 26. Epub 2021 Jul 26.

Department of Tumor Biology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

The value of high-throughput germline genetic testing is increasingly recognized in clinical cancer care. Disease-associated germline variants in cancer patients are important for risk management and surveillance, surgical decisions and can also have major implications for treatment strategies since many are in DNA repair genes. With the increasing availability of high-throughput DNA sequencing in cancer clinics and research, there is thus a need to provide clinically oriented sequencing reports for germline variants and their potential therapeutic relevance on a per-patient basis. Read More

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Bisphosphonate treatment in children with acute lymphoblastic leukemia and osteonecrosis - radiological and clinical findings in a national cohort.

Acta Oncol 2021 Jul 26:1-6. Epub 2021 Jul 26.

Department of Pediatrics and Adolescent Medicine, Oulu University Hospital, Oulu, Finland.

Osteonecrosis (ON) is a recognized complication of childhood ALL, but its optimal management remains unestablished. This study evaluated the effect of bisphosphonate (BP) treatment on the evolution of ON lesions in childhood ALL. We included a national cohort of ALL patients diagnosed with symptomatic ON before 18 years of age and treated with BPs ( = 10; five males). Read More

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Reconstruction of the evolutionary biogeography reveal the origins and diversification of oysters (Bivalvia: Ostreidae).

Mol Phylogenet Evol 2021 Jul 22;164:107268. Epub 2021 Jul 22.

Department of Marine Organism Taxonomy and Phylogeny, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, Shandong 266071, China; Center for Ocean Mega-Science, Chinese Academy of Sciences, Qingdao, Shandong 266071, China. Electronic address:

Oysters (Bivalvia: Ostreidae Rafinesque, 1815) live in the intertidal and shallow subtidal areas worldwide. Despite their long evolutionary histories, abundant fossil records, global distribution, and ecological significance, a systematic time-dependent biogeographical analysis of this family is still lacking. Using combined mitochondrial (COI and 16S rRNA) and nuclear (18S rRNA, 28S rRNA, H3 and ITS2) gene makers for 80% (70/88) of the recognized extant Ostreidae, we reconstructed the global phylogenetic and biogeographical relationships throughout the evolutionary history of oysters. Read More

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Pharmacists Are Not Mid-Level Providers.

Am J Pharm Educ 2021 Jul 22:8556. Epub 2021 Jul 22.

American Association of Colleges of Pharmacy, Arlington, Virginia

Written by members of the 2021 AACP Professional Affairs Committee, this commentary describes the perspective on why pharmacists should not be classified as "mid-level" providers.  Beyond the connotation that this classification implies that there are different levels or a hierarchy of providers, it is important to recognize that all healthcare providers bring unique and essential knowledge and contributions to the healthcare team and to patients.  Timely issues germane to pharmacists, including dependent and independent practice, provider status, and professional identity also contribute to the rationale that pharmacists, just like all other healthcare providers, should be classified by their professional identity. Read More

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Identification and Characterization of Multiple Myeloma Stem Cell-Like Cells.

Cancers (Basel) 2021 Jul 14;13(14). Epub 2021 Jul 14.

Department of Hematology, the Second Xiangya Hospital, Molecular Biology Research Center, School of Life Sciences, Hunan Province Key Laboratory of Basic and Applied Hematology, Central South University, Changsha 410011, China.

Multiple myeloma (MM) is a B-cell tumor of the blood system with high incidence and poor prognosis. With a further understanding of the pathogenesis of MM and the bone marrow microenvironment, a variety of adjuvant cell therapies and new drugs have been developed. However, the drug resistance and high relapse rate of MM have not been fundamentally resolved. Read More

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The Genetic Analyses of French Canadians of Quebec Facilitate the Characterization of New Cancer Predisposing Genes Implicated in Hereditary Breast and/or Ovarian Cancer Syndrome Families.

Cancers (Basel) 2021 Jul 7;13(14). Epub 2021 Jul 7.

Department of Human Genetics, McGill University, Montreal, QC H3A 1A1, Canada.

The French Canadian population of the province of Quebec has been recognized for its contribution to research in medical genetics, especially in defining the role of heritable pathogenic variants in cancer predisposing genes. Multiple carriers of a limited number of pathogenic variants in and , the major risk genes for hereditary breast and/or ovarian cancer syndrome families, have been identified in French Canadians, which is in stark contrast to the array of over 2000 different pathogenic variants reported in each of these genes in other populations. As not all such cancer syndrome families are explained by and , newly proposed gene candidates identified in other populations have been investigated for their role in conferring risk in French Canadian cancer families. Read More

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Hypoxia and glucose metabolism assessed by FMISO and FDG PET for predicting IDH1 mutation and 1p/19q codeletion status in newly diagnosed malignant gliomas.

EJNMMI Res 2021 Jul 21;11(1):67. Epub 2021 Jul 21.

Department of Neurological Surgery, Faculty of Medicine, Kagawa University, Miki-cho, Kagawa, Japan.

Background: Tumor hypoxia and glycolysis have been recognized as determinant factors characterizing tumor aggressiveness in malignant gliomas. To clarify in vivo hypoxia and glucose metabolism in relation to isocitrate dehydrogenase (IDH) mutation and chromosome 1p and 19q (1p/19q) codeletion status, we retrospectively analyzed hypoxia as assessed by positron emission tomography (PET) with [F]-fluoromisonidazole (FMISO) and glucose metabolism as assessed by PET with [F]-fluoro-2-deoxy-D-glucose (FDG) in newly diagnosed malignant gliomas.

Methods: In total, 87 patients with newly diagnosed supratentorial malignant (WHO grade III and IV) gliomas were enrolled in this study. Read More

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Acute-care hospitalizations among First Nations people, Inuit and Métis: Results from the 2006 and 2011 Canadian Census Health and Environment Cohorts.

Authors:
Evelyne Bougie

Health Rep 2021 Jul;32(7):11-26

Health Analysis Division, Statistics Canada, Ottawa, Ontario.

Background: The objective of this study was to describe sex-specific hospitalization rates among Indigenous people in Canada (excluding Quebec), separately for First Nations people living on and off reserve, Inuit living in Inuit Nunangat (excluding Nunavik), Métis, and the non-Indigenous population.

Data And Methods: The 2006 and 2011 Canadian Census Health and Environment Cohorts (CanCHECs) were used, allowing hospital records to be examined by Indigenous identity as reported on the census. Five years of hospitalization data were used for each CanCHEC. Read More

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Evaluation of measurable residual disease in multiple myeloma by multiparametric flow cytometry: Current paradigm, guidelines, and future applications.

Int J Lab Hematol 2021 Jul;43 Suppl 1:43-53

Department of Flow and Image Cytometry, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.

Multiple myeloma (MM) is a heterogeneous group of mature B-cell diseases that are typically characterized by the presence and accumulation of abnormal plasma cells (PCs), which results in the excess production of monoclonal immunoglobulin and/or light chain found in the serum and/or urine. Multiparametric flow cytometry (MFC) is an indispensable tool to supplement the diagnosis, classification and monitoring of the disease due to its high patient applicability, excellent sensitivity and encouraging results from various clinical trials. In this regard, minimal or, more appropriately, measurable residual disease (MRD) negativity by MFC has been recognized as a powerful predictor of favourable long-term outcomes. Read More

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Early Interventions for Infants at Risk for Developmental Impairment: The South Asian Perspective.

Indian J Pediatr 2021 Jul 21. Epub 2021 Jul 21.

Department of Disability Studies, Faculty of Medicine, University of Kelaniya, Sri Lanka Ayati National Centre for Children With Disabilities, North Colombo, Teaching Hospital, P O Box 6, Thalagolla Road, Ragama, 11010, Sri Lanka.

Majority of under-five children with developmental disabilities live in low- and middle-income countries (LMIC). A considerable proportion of disabilities results from perinatal adversities. The neonatal and infant mortality rates in India, Bangladesh, and Sri Lanka have improved over the last two decades, implying survival of infants at risk for developmental impairments. Read More

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One-class classification of special agroforestry Brazilian coffee using NIR spectrometry and chemometric tools.

Food Chem 2021 Jun 26;366:130480. Epub 2021 Jun 26.

Núcleo Avançado de Tecnologias Analíticas (NATA), Universidade da Integração Internacional da Lusofonia Afro-brasileira (Unilab), Brazil. Electronic address:

The near-infrared spectrometry combined with the one-class classification method was applied as quality control of the agroforestry-grown specialty coffee. A total of 34 samples were analyzed in this study. Spectral data were obtained using a NIR portable and different pre-treatment strategies for baseline correction were evaluated. Read More

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Genome-wide SNP analysis to assess the genetic population structure and diversity of Acrocomia species.

PLoS One 2021 20;16(7):e0241025. Epub 2021 Jul 20.

Centro de Pesquisa de Recursos Genéticos Vegetais, Instituto Agronômico-IAC, Campinas-SP, Brazil.

Acrocomia (Arecaceae) is a genus widely distributed in tropical and subtropical America that has been achieving economic interest due to the great potential of oil production of some of its species. In particular A. aculeata, due to its vocation to supply oil with the same productive capacity as the oil palm (Elaeis guineenses) even in areas with water deficit. Read More

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Changes in Lumbosacral Anatomy and Vertebral Numbering in Patients with Thoracolumbar and/or Lumbosacral Transitional Vertebrae.

JB JS Open Access 2021 Jul-Sep;6(3). Epub 2021 Jul 14.

Spine Center, Yokohama Minami Kyosai Hospital, Kanagawa, Japan.

The presence of a thoracolumbar transitional vertebra (TLTV) and/or lumbosacral transitional vertebra (LSTV) may cause wrong-site surgery and problems while measuring spinopelvic parameters, including pelvic incidence and lumbar lordosis. The Castellvi classification of LSTV addresses coronal images but not sagittal or axial images. Therefore, it is unclear how LSTV differs from the normal lumbosacral anatomy. Read More

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[Yips in Kyudo (Japanese archery): prevalence, classification, and aggravating factors].

Rinsho Shinkeigaku 2021 Jul 17. Epub 2021 Jul 17.

Department of Neurology, Gifu University Graduate School of Medicine.

In Kyudo (Japanese archery), there are four disorders that hinder an archer's performance: Hayake (releasing the bow too early), Motare (unable to release the bow when intended), Biku (jerking when aiming), and Yusuri (shaking when drawing the bow, or aiming). These disorders are similar to Yips, a psycho-neuromuscular movement disorder, recognized in various sports, but few studies have examined yips in Kyudo. This study examined the frequency, classification, and risk factors of yips in Kyudo among medical students. Read More

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Metabolomic analysis to discriminate drug-induced liver injury (DILI) phenotypes.

Arch Toxicol 2021 Jul 17. Epub 2021 Jul 17.

Unidad de Hepatología Experimental, Health Research Institute La Fe, Valencia, Spain.

Drug-induced liver injury (DILI) is an adverse toxic hepatic clinical reaction associated to the administration of a drug that can occur both at early clinical stages of drug development, as well after normal clinical usage of approved drugs. Because of its unpredictability and clinical relevance, it is of medical concern. Three DILI phenotypes (hepatocellular, cholestatic, and mixed) are currently recognized, based on serum alanine aminotransferase (ALT) and alkaline phosphatase (ALP) values. Read More

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Genome-wide analysis and expression patterns of lipid phospholipid phospholipase gene family in Brassica napus L.

BMC Genomics 2021 Jul 18;22(1):548. Epub 2021 Jul 18.

Oil Crops Research Institute, Key Laboratory of Biology and Genetic Improvement of Oil Crops, Chinese Academy of Agricultural Sciences (CAAS), Ministry of Agriculture, 430062, Wuhan, Hubei, China.

Background: Lipid phosphate phosphatases (LPP) are critical for regulating the production and degradation of phosphatidic acid (PA), an essential signaling molecule under stress conditions. Thus far, the LPP family genes have not been reported in rapeseed (Brassica napus L.). Read More

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sp. nov., isolated from mangrove soil and the proposal for the reclassification of as comb. nov.

Int J Syst Evol Microbiol 2021 Jul;71(7)

Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, State Key Laboratory of Applied Microbiology Southern China, Guangdong Open Laboratory of Applied Microbiology, Guangdong Microbial Culture Collection Center (GDMCC), Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, PR China.

A novel Gram-stain-negative, aerobic and rod-shaped bacterial strain designated as 6D45A was isolated from mangrove soil and characterized using a polyphasic taxonomic approach. Strain 6D45A was found to grow at 10-37 °C (optimum, 28 °C), at pH 6.0-9. Read More

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sp. nov., isolated from soil.

Int J Syst Evol Microbiol 2021 Jul;71(7)

Department of Microbiology and Molecular Biology, College of Bioscience and Biotechnology, Chungnam National University, 99, Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea.

A Gram-stain-negative, oxidase-positive, catalase-positive, aerobic, orange-pigmented, rod-shaped and non-motile bacterium designated strain MMS17-SY002 was isolated from island soil. The isolate grew at 20-37 °C (optimum, 30 °C), at pH 6.0-9. Read More

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A pediatric cerebral tumor with MN1 alteration and pathological features mimicking carcinoma metastasis: may the terminology "high grade neuroepithelial tumor with MN1 alteration" still be relevant?

Childs Nerv Syst 2021 Jul 16. Epub 2021 Jul 16.

Department of Neurosurgery, Acibadem Maslak Hospital, Istanbul, Turkey.

Introduction: Astroblastoma, MN1-altered (old name: high-grade neuroepithelial tumor/HGNET with MN1 alteration) is a recently described central nervous system tumor mostly affecting pediatric patients and profoundly young girls. Differential pathological diagnoses of these tumors include ependymoma, pleomorphic xanthoastrocytoma, embryonal tumor with multilayered rosettes, meningioma, and even glioblastoma. As the treatment approaches to these tumors differ, it is essential to increase the awareness about these tumors in the neurosurgical community. Read More

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Multigene phylogeny and taxonomic revision of American shrimps of the genus Dana, 1852 (Decapoda, Palaemonidae) implies a proposal for reversal of precedence with Spence Bate, 1868.

Zookeys 2021 1;1047:155-198. Epub 2021 Jul 1.

Colección Nacional de Crustáceos, Instituto de Biología, Universidad Nacional Autónoma de México, Apartado Postal 70-153, 04510 Ciudad de México, Mexico Universidad Nacional Autónoma de México Mexico Mexico.

The freshwater shrimp genus Dana, 1852 has a disjunct distribution in North (Mexico) and South (Brazil, Chile) America, and is composed of only six species. The current classification of genera in the Palaemonidae is controversial, based on variable morphological characters, and still far from a clear definition. differs from the speciose genus Spence Bate, 1868 only by the absence of the hepatic spines on the carapace. Read More

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