1,416 results match your criteria recipients focused

Pain or gain? Understanding how trait empathy impacts leader effectiveness following the provision of negative feedback.

J Appl Psychol 2021 Apr 8. Epub 2021 Apr 8.

Although providing negative performance feedback can enhance employee performance, leaders are sometimes reluctant to engage in this activity. Reflecting this, prior research has identified negative feedback provision as an aversive, yet potentially rewarding, managerial activity. However, little is known about how providing negative feedback impacts the effectiveness of leaders who do so. Read More

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Palliative care for patients undergoing stem cell transplant: intervention components and supportive care measures.

Bone Marrow Transplant 2021 Apr 6. Epub 2021 Apr 6.

Massachusetts General Hospital, Boston, MA, USA.

An inpatient palliative care intervention during HCT led to improvement in patient QOL and mood. We sought to describe components of the intervention, investigate differences in supportive care practices by treatment arm, and explore whether these differences mediated the impact of the intervention on patient QOL and mood. We conducted a secondary analysis of a randomized trial investigating inpatient palliative care integrated with transplant care versus standard transplant care for HCT recipients. Read More

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When using donor oocytes, does embryo stage matter? An analysis of blastocyst versus cleavage stage embryo transfers using a cryopreserved donor oocyte bank.

J Assist Reprod Genet 2021 Apr 5. Epub 2021 Apr 5.

Division of Reproductive Endocrinology and Infertility, Department of Gynecology and Obstetrics, Emory University School of Medicine, 550 Peachtree Street, Atlanta, GA, 30308, USA.

Purpose: Oocyte donor in vitro fertilization (IVF) represents an ideal model to study the effects of embryo stage on reproductive success, as embryos come from young women with high-quality oocytes. Our study aimed to determine if embryo transfer stage affected outcomes in oocyte donor IVF, including the common scenario where only a limited number of quality embryos are available after culture.

Methods: This retrospective cohort analyzed anonymous vitrified donor oocyte cycles at a single clinic between 2008 and 2015. Read More

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What do the potential recipients of disclosure of OSA say? Perspectives from adolescent residents in Scotland and Chile.

Child Abuse Negl 2021 Apr 2;117:105034. Epub 2021 Apr 2.

School of Health in Social Sciences, The University of Edinburgh, United Kingdom; Escuela de Psicología, Facultad de Ciencias Sociales y Comunicaciones, Universidad Santo Tomás, Chile.

Background: With the increase in internet use, new forms of child victimization like Online Sexual Abuse (OSA) have emerged. Children and adolescents rarely disclose these incidents and most disclosure happens around peers.

Objective: This research addresses the perspective of adolescents (not victims of OSA), potential recipients of the disclosure, within the context of disclosure of OSA committed by either adult or peer perpetrators. Read More

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Medication non-adherence among liver transplant recipients.

Curr Hepatol Rep 2020 Dec 24;19(4):327-336. Epub 2020 Oct 24.

Division of Gastroenterology and Hepatology, University of Pennsylvania Perelman School of Medicine.

Purpose Of Review: We provide an overview of the recent evidence on the prevalence, risk factors, and consequences of medication non-adherence (NA) in liver transplant (LT) recipients.

Recent Findings: NA in LT is associated with socio-demographic and medication-related factors, low social support, and poor health literacy. Patient-reported adherence is one of the most common methods to measure NA using validated assessments; immunosuppression (IS) drug levels and electronic monitoring may also be used. Read More

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December 2020

Hormonal (Im)Balance and Reproductive System's Disorders in Transplant Recipients-A Review.

Biology (Basel) 2021 Mar 26;10(4). Epub 2021 Mar 26.

Department of Histology and Embryology, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.

The rising need for treatment of end stage of organ failure results in an increased number of graft recipients yearly. The most commonly transplanted organs are kidney, heart, liver, bone marrow, lung and skin. The procedure of transplantation saves and prolongs the lives of chronically ill patients or at least improves the quality. Read More

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Mutual support between patients and family caregivers in palliative care: A systematic review and narrative synthesis.

Palliat Med 2021 Apr 2:269216321999962. Epub 2021 Apr 2.

Discipline of Occupational Therapy, School of Medicine, Trinity College Dublin, Dublin, Ireland.

Background: Patients in palliative care are usually conceptualised as recipients of support from family caregivers. Family caregivers in palliative care are typically defined as providers of support to patients. Little is known about reciprocal dimensions of support provision between patients and family caregivers in palliative care. Read More

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Two-phase survey on the frequency of use and safety of MRI for hearing implant recipients.

Eur Arch Otorhinolaryngol 2021 Mar 31. Epub 2021 Mar 31.

Karolinska University Hospital, Solna, Sweden.

Purpose: Magnetic resonance imaging (MRI) is often used to visualize and diagnose soft tissues. Hearing implant (HI) recipients are likely to require at least one MRI scan during their lifetime. However, the MRI scanner can interact with the implant magnet, resulting in complications for the HI recipient. Read More

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Characteristics of Copayment Offsets for Prescription Drugs in the United States.

JAMA Intern Med 2021 Mar 29. Epub 2021 Mar 29.

Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.

Importance: Despite ongoing debate regarding the high prices that patients pay for prescription drugs, to our knowledge, little is known regarding the use of coupons, vouchers, and other types of copayment "offsets" that reduce patients' out-of-pocket drug spending. Although offsets reduce patients' immediate cost burden, they may encourage the use of higher-cost products and diminish health insurers' ability to optimize pharmaceutical value.

Objective: To examine the drugs most commonly covered by offsets, the percentage of out-of-pocket costs covered by offsets, and the characteristics of patients using offsets for retail pharmacy transactions in the United States in 2017 through 2019. Read More

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Comparative antibody responses to the live-attenuated and recombinant herpes zoster vaccines.

J Virol 2021 Mar 24. Epub 2021 Mar 24.

Department of Pediatrics, University of Colorado Denver School of Medicine, Anschutz Medical Campus, Aurora, CO, USA.

Two herpes zoster (HZ) vaccines licensed in the United States are recommended by the Advisory Committee on Immunization Practices (ACIP): 1) live-attenuated vaccine (ZVL) using vOka strain varicella-zoster virus (VZV), and 2) recombinant adjuvanted vaccine (RZV) containing recombinant VZV glycoprotein E (gE). Two phase 3 clinical trials of RZV led the Advisory Committee on Immunization Practices (ACIP) to recommend it with preferred status.VZV T cell-mediated immunity (CMI), but not humoral immunity, are considered essential for protection against HZ. Read More

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Determinants of primary and non-primary informal care-giving to home-based palliative care cancer care-recipients in Ontario, Canada.

Health Soc Care Community 2021 Mar 24. Epub 2021 Mar 24.

Institute of Health Policy, Management and Evaluation, University of Toronto, Health Sciences Building, Toronto, ON, Canada.

Informal care plays an important role in the care of care-recipients. Most of the previous studies focused on the primary caregivers and ignored the importance of non-primary caregivers. Moreover, little is known about the provision of informal care in the context of home-based palliative care. Read More

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Comparison of imidacloprid, propiconazole, and nanopropiconazole effects on the development, behavior, and gene expression biomarkers of the Pacific oyster (Magallana gigas).

Sci Total Environ 2021 Apr 10;764:142921. Epub 2020 Oct 10.

Univ. Bordeaux, CNRS, EPOC, EPHE, UMR 5805, F-33600 Pessac, France. Electronic address:

Coastal areas are final recipients of various contaminants including pesticides. The effects of pesticides on non-target organisms are often unclear, especially at environmentally relevant concentrations. This study investigated the impacts of insecticide imidacloprid (IMI) and fungicide propiconazole (PRO), some of the most detected pesticides in the Arcachon Bay in France. Read More

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Adoptive Transfer of Regulatory Immune Cells in Organ Transplantation.

Front Immunol 2021 2;12:631365. Epub 2021 Mar 2.

Department of Surgery, Medical University of South Carolina, Charleston, SC, United States.

Chronic graft rejection remains a significant barrier to solid organ transplantation as a treatment for end-organ failure. Patients receiving organ transplants typically require systemic immunosuppression in the form of pharmacological immunosuppressants for the duration of their lives, leaving these patients vulnerable to opportunistic infections, malignancies, and other use-restricting side-effects. In recent years, a substantial amount of research has focused on the use of cell-based therapies for the induction of graft tolerance. Read More

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Comparative bibliometric analysis of publications by past Royal Australasian College of Surgeons research scholarship recipients.

ANZ J Surg 2021 Mar 18. Epub 2021 Mar 18.

Research Audit and Academic Surgery, Royal Australasian College of Surgeons, Adelaide, South Australia, Australia.

Background: The Royal Australasian College of Surgeons awards scholarships to surgeons, surgical trainees and recipients focused on developing their clinical knowledge and improving outcomes for patients. A bibliometric analysis of research scholarship recipients publications and h-index scores was conducted to understand the benefits of receiving these scholarships.

Methods: A bibliometric analysis of Royal Australasian College of Surgeons scholarship recipients in 2015 was performed using Open Researcher and Contributor ID (ORCID), Scopus, Google Scholar, ResearchGate, LinkedIn and PubMed to identify the number of publications, h-index scores, field-weighted citation impact and the relative citation ratio. Read More

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Clinical consequences of head and neck free-flap reconstructions in the DM population.

Sci Rep 2021 Mar 16;11(1):6034. Epub 2021 Mar 16.

Division of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Yun-Lin Branch, Dou-Liu City, Taiwan.

Diabetes mellitus (DM) is a common comorbidity and risk factor for postoperative complications in head and neck (H&N) microsurgical reconstructions. Our study focused on the association between DM and individual complications regarding both surgical and medical aspects. A meta-analysis of English-language articles comparing a series of complications between DM and non-DM H&N free-flap recipients was performed by comprehensive meta-analysis (CMA). Read More

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Evidence of SARS-CoV-2 Infection in Cells, Tissues and Organs and the Risk of Transmission Through Transplantation.

Transplantation 2021 Mar 10. Epub 2021 Mar 10.

Medical Affairs and Innovation, Héma-Québec, Québec, QC, Canada Children's Hospital of Eastern Ontario Research Institute, Ottawa, ON, Canada Canadian Blood Services, Ottawa, ON, Canada Medical Affairs and Innovation, Héma-Québec, Saint-Laurent, QC, Canada Centre for Outcomes Research and Evaluation (CORE), Research Institute of McGill University Health Centre, Montréal, QC, Canada Division of Nephrology and the Multi Organ Transplant Program, Royal Victoria Hospital, McGill University Health Centre, Montréal, QC, Canada Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montréal, QC, Canada Canadian Blood Services, Edmonton, AB, Canada Laboratory Medicine and Pathology, University of Alberta, Edmonton, AB, Canada Population Health and Optimal Health Practices Research Unit, Trauma-Emergency-Critical Care Medicine, CHU de Québec, Université Laval Research Center, Québec, QC, Canada. Pediatrics Department, Intensive Care Division, Faculté de Médecine, Université Laval, Québec, QC, Canada. Transplant Québec, Montréal, QC, Canada. Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC, Canada.

The emergence of the SARS-CoV-2 virus responsible for the COVID-19 pandemic has raised concerns for programs overseeing donation and transplantation of cells, tissues and organs (CTO) that this virus might be transmissible by transfusion or transplantation. Transplant recipients are considered particularly vulnerable to pathogens due to immunosuppression, and SARS-CoV-2 is likely to generate complications if contracted. Several signs and symptoms observed in COVID-19 positive patients reflect damage to multiple organs and tissues, raising the possibility of extra-pulmonary SARS-CoV-2 infections and risk of transmission. Read More

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Using mitochondrial activity to select for potent human hematopoietic stem cells.

Blood Adv 2021 Mar;5(6):1605-1616

Department of Cell, Developmental & Regenerative Biology.

Hematopoietic cell transplantation is a critical curative approach for many blood disorders. However, obtaining grafts with sufficient numbers of hematopoietic stem cells (HSCs) that maintain long-term engraftment remains challenging; this is due partly to metabolic modulations that restrict the potency of HSCs outside of their native environment. To address this, we focused on mitochondria. Read More

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Pneumococcal pneumonia in adult hospitalised solid organ transplant recipients: Nationwide, population-based surveillance.

Int J Clin Pract 2021 Feb 27:e14126. Epub 2021 Feb 27.

Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University, Taichung, Taiwan.

Background: Pneumococcal disease poses a burden to the community in high risk population. Most early studies focused on invasive pneumococcal disease. However, the epidemiology of pneumococcal pneumonia (PP) requiring hospitalisation in solid organ transplant recipients (SOTRs) is poorly defined. Read More

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February 2021

Optimizing patient partnership in primary care improvement: A qualitative study.

Health Care Manage Rev 2021 Apr-Jun 01;46(2):123-134

Background: The need to expand and better engage patients in primary care improvement persists.

Purpose: Recognizing a continuum of forms of engagement, this study focused on identifying lessons for optimizing patient partnerships, wherein engagement is characterized by shared decision-making and practice improvement codesign.

Methodology: Twenty-three semistructured interviews with providers and patients involved in improvement efforts in seven U. Read More

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February 2021

A New Approach for Treatment of Woman With Absolute Uterine Factor Infertility: A Traditional Review of Safety and Efficacy Outcomes in the First 65 Recipients of Uterus Transplantation.

Cureus 2021 Jan 18;13(1):e12772. Epub 2021 Jan 18.

Anaesthesiology, German-Yemeni Hospital, Sana'a, YEM.

Uterine transplantation restores fertility in women with absolute uterine factor infertility and allows the opportunity to conceive, experience gestation, and acquire motherhood. The number of cases being performed is increasing dramatically, with detailed outcomes from 65 cases now available. Pregnancies achieved through uterus transplantation and following in vitro fertilization (IVF) are associated with an increased risk for further mother and newborn babies. Read More

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January 2021

A consequentialist ethical analysis of federal funding of elective abortions.

Bioethics 2021 Feb 16. Epub 2021 Feb 16.

Baylor College of Medicine, Center for Medical Ethics and Health Policy, Houston, Texas, USA.

Insurance coverage of abortion varies widely across the United States and is an extensively debated issue. Medicaid coverage of abortion is particularly relevant because the majority of abortion patients are poor or low-income and are thus often covered by Medicaid. Since the Hyde Amendment was first passed in 1976, federal Medicaid funds have been banned from covering the costs of elective abortion. Read More

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February 2021

Acceptability of a Mobile Health Behavior Change Intervention for Cancer Survivors With Obesity or Overweight: Nested Mixed Methods Study Within a Randomized Controlled Trial.

JMIR Mhealth Uhealth 2021 Feb 16;9(2):e18288. Epub 2021 Feb 16.

School of Psychology, National University of Ireland, Galway, Galway, Ireland.

Background: A significant proportion of cancer survivors have overweight or obesity. Although this has negative implications for health, weight management is not a standard component of oncology aftercare. Mobile health (mHealth) technology, in combination with behavior change techniques (BCTs), has the potential to support positive lifestyle changes. Read More

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February 2021

Diminishing returns drive altruists to help extended family.

Nat Ecol Evol 2021 Apr 15;5(4):468-479. Epub 2021 Feb 15.

School of Biological Sciences, University of Bristol, Bristol, UK.

Altruism between close relatives can be easily explained. However, paradoxes arise when organisms divert altruism towards more distantly related recipients. In some social insects, workers drift extensively between colonies and help raise less related foreign brood, seemingly reducing inclusive fitness. Read More

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Two Cases of Pregnancy Following Uterine Transplant: An Ethical Analysis.

Narrat Inq Bioeth 2020 ;10(3):263-268

Uterine factor infertility (UFI) affects 1-5% of women of reproductive age, and uterus transplantation is the only option available to these women for carrying a pregnancy. The ethical analysis of uterus transplantation focuses on the value and experience of pregnancy in recipients; to date, however, no personal experiences with pregnancy after uterus transplantation have been published. The authors share the stories of two of our uterus transplant recipients, obtained through semi-structured, in-person interviews. Read More

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January 2020

Effects of Hematopoietic Cell Transplantation on the Pulmonary Immune Response to Infection.

Front Pediatr 2021 26;9:634566. Epub 2021 Jan 26.

Department of Pediatrics, Division of Critical Care Medicine, University of Minnesota Medical School, Minnesota, MN, United States.

Pulmonary infections are common in hematopoietic cell transplant (HCT) patients of all ages and are associated with high levels of morbidity and mortality. Bacterial, viral, fungal, and parasitic pathogens are all represented as causes of infection. The lung mounts a complex immune response to infection and this response is significantly affected by the pre-HCT conditioning regimen, graft characteristics, and ongoing immunomodulatory therapy. Read More

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January 2021

The psychosocial experiences and supportive care preferences of organ transplant recipients and their carers who live in regional Australia.

Aust J Rural Health 2021 Feb 7;29(1):92-105. Epub 2021 Feb 7.

School of Psychology, University of Adelaide, Adelaide, SA, Australia.

Background: There is no evidence that being a rural or regional organ transplant recipient has adverse physical health outcomes post-surgery compared with those experienced by people living in cities, but the impact of living remotely from transplant centres on psychosocial outcomes has not been explored.

Objective: To identify the social, emotional, psychological, spiritual, informational and practical issues associated with being a regionally based organ transplant recipient or carer and determine how support services could be improved for this group.

Design/ Setting/ Participants: Twenty-two purposively sampled adult Australians who lived outside metropolitan centres and had received an organ transplant (n = 15) or were the primary carer of someone who had received one (n = 7), participated in semi-structured, telephone interviews. Read More

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February 2021

Determinants of caregiving burden among informal caregivers of adult care recipients with chronic illness.

J Clin Nurs 2021 Feb 2. Epub 2021 Feb 2.

Instituto de Investigación Sanitaria Galicia Sur, Vigo, Spain.

Aims And Objectives: This study examined the predictors of caregiver burden based on patient and caregiver characteristics in a sample of Spanish caregivers looking after adult patients with chronic disease. The effect of task type and patient-caregiver interaction is also analysed.

Background: Specific predictors of caregiver burden have been widely examined in the literature. Read More

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February 2021

Utilizing multimodal analgesia to evaluate postoperative analgesic requirements in kidney transplant recipients.

Clin Transplant 2021 Feb 1:e14240. Epub 2021 Feb 1.

Department of Surgery, Division Abdominal Transplant Surgery, University of North Carolina Medical Center, Chapel Hill, NC, USA.

The use of non-opioid analgesics following surgery has proven beneficial in managing pain and decreasing adverse outcomes following surgery. Data assessing outcomes related to opioid use is limited in kidney transplant recipients (KTRs). We evaluated the effectiveness of implementing a reduced to no opioid use protocol in KTRs. Read More

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February 2021

Fear of Movement and Physical Self-Efficacy Partially Mediate the Association Between Fatigue and Physical Activity Among Kidney Transplant Recipients.

Clin Nurs Res 2021 Jan 29:1054773821990263. Epub 2021 Jan 29.

Department of Rehabilitation Sciences, Hong Kong Polytechnic University, China.

Fatigue is one of the most distressing symptoms in renal transplant patients, causing functional impairment and worsening their quality of life. However, the mechanism by which fatigue affects physical activity is unclear. A cross-sectional study using a convenient sampling approach was utilized to investigate 665 kidney transplant recipients recruited from the transplantation centers of six general hospitals from July and September 2019. Read More

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January 2021