J Biomech 2021 Mar 15;121:110381. Epub 2021 Mar 15.
Multiscale Materials Modeling Lab, Department of Mechanical Engineering, University of Arkansas, Fayetteville, AR, USA; Institute for Nanoscience and Engineering, 731 W. Dickson Street, University of Arkansas, Fayetteville, AR, USA. Electronic address:
Peptoids as an extracellular matrix (ECM) material is gaining importance in in vitro neuronal cell culture studies due to their biocompatibility, self-assembling structure, and stability. Mechanotransduction between a neuronal cell and an ECM is mediated by neuronal cell receptors such as integrin and neural cellular adhesion molecule. In this study, using molecular dynamics, we investigate the interaction energies between peptoid and neuronal cell receptors, and also study the effect of peptoid bundle size. Read More