106,757 results match your criteria received behavioral

Melatonin administration attenuates acute stress by inducing sleep state in zebrafish (Danio rerio).

Comp Biochem Physiol C Toxicol Pharmacol 2021 Apr 7;246:109044. Epub 2021 Apr 7.

Federal University of Lavras, Graduate Program in Veterinary Sciences, Department of Veterinary Medicine, Lavras, MG, Brazil. Electronic address:

Melatonin plays a fundamental homeostatic role in basic biological functions, and an anti-stress role has been also proposed for this hormone. This study aimed to evaluate hormonal, enzymatic and behavioral parameters of zebrafish that received administration of melatonin and were submitted to acute stress. A total of 120 wild-type zebrafish were divided into five groups: naïve control (N), negative control group (Stress/C), positive control treated with diazepam (Stress/Diaz), treatment with melatonin at dose 1 (Stress/Melt. Read More

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Association of gender and systemic therapy treatment outcomes in psoriasis: a two-country, multi-centre, prospective, non-interventional registry study.

Br J Dermatol 2021 Apr 10. Epub 2021 Apr 10.

Department of Dermatology, University Hospital Zurich, Zurich, Switzerland.

Background: Psoriasis is a stigmatizing disease that often affects female patients more negatively than male patients. Very little systematic data on the treatment responses related to gender exists.

Objectives: This two-country, multi-centre, prospective, non-interventional registry study aimed to evaluate potential gender differences with respect to systemic anti-psoriatic treatment. Read More

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A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease.

Alzheimers Res Ther 2021 Apr 9;13(1):76. Epub 2021 Apr 9.

Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, Brisbane, QLD, 4072, Australia.

Background: Aducanumab is an anti-amyloid-β (Aβ) antibody that achieved reduced amyloid pathology in Alzheimer's disease (AD) trials; however, it is controversial whether it also improved cognition, which has been suggested would require a sufficiently high cumulative dose of the antibody in the brain. Therapeutic ultrasound, in contrast, has only begun to be investigated in human AD clinical trials. We have previously shown that scanning ultrasound in combination with intravenously injected microbubbles (SUS), which temporarily and safely opens the blood-brain barrier (BBB), removes amyloid and restores cognition in APP23 mice. Read More

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Altered acoustic startle, prepulse facilitation, and object recognition memory produced by corticosterone withdrawal in male rats.

Behav Brain Res 2021 Apr 6:113291. Epub 2021 Apr 6.

Division of Medical Sciences, University of Victoria, Victoria, BC, V8W 2Y2, Canada.

The symptoms of human depression often include cognitive deficits. However, cognition is not frequently included in the behavioral assessments conducted in preclinical models of depression. For example, it is well known that repeated corticosterone (CORT) injections in rodents produce depression-like behavior as measured by the forced swim test, sucrose preference test, and tail suspension test, but the cognitive impairments produced by repeated CORT have not been thoroughly examined. Read More

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Examining How Health Navigation Affects Mental Health Among Gay, Bisexual, and Other Men Who Have Sex with Men Living with Human Immunodeficiency Virus in Guatemala.

AIDS Patient Care STDS 2021 Apr;35(4):126-133

Department of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Gay, bisexual, and other men who have sex with men (GBMSM) are disproportionately affected by mental health problems and human immunodeficiency virus (HIV). Health navigation has the potential to improve both HIV and mental health outcomes; however, few studies have measured the impact of navigation on mental health among people living with HIV. We analyzed longitudinal data from a sociobehavioral survey and navigation monitoring system with GBMSM living with HIV in Guatemala ( = 346) that participated in a 12-month differentiated care intervention. Read More

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Transition Planning from Jail; Treatment Engagement, Continuity of Care, and Rearrest.

Community Ment Health J 2021 Apr 9. Epub 2021 Apr 9.

Center for Behavioral Health and Justice, School of Social Work, Wayne State University, 5447 Woodward Avenue, Detroit, MI, 48202, USA.

Mental illness is experienced at a higher rate among incarcerated individuals than the general population. This study is one of the first assessing the association of a jail-based mental health (MH) transition planning program with continuity of care (CoC) (defined as no gap in treatment upon reentry), behavioral health treatment engagement, and rearrest. A one group pre-posttest design merged three data sources: program, community-based MH treatment, and jail data. Read More

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Initial Experience Treating HPV-Related Laryngeal Diseases with Oral Brincidofovir: A Pilot Study.

Ann Otol Rhinol Laryngol 2021 Apr 9:34894211007227. Epub 2021 Apr 9.

Bastian Voice Institute, Downers Grove, IL, USA.

Objective: To determine if brincidofovir, an oral analog of cidofovir that achieves high tissue levels of the active metabolite with low systemic toxicity, has an observable effect on HPV-related disease of the larynx.

Methods: Two patients with laryngeal recurrent respiratory papillomatosis (one each of genotypes 6 and 11) and 1 with recurring aryepiglottic fold (genotype 16) received oral brincidofovir according to protocol. Close-range videoendoscopic examinations were done during and after the study period to observe disease behavior in the absence of other interventions, and after subsequent surgical intervention. Read More

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Behavioral and stress responses to feeding time in pregnant sows under limit-fed regime.

J Anim Sci 2021 Apr 9. Epub 2021 Apr 9.

Southern Research and Outreach Center, University of Minnesota, Waseca, MN, USA.

We investigated the effect of feeding time on behavior and stress responses in pregnant sows under isocaloric conditions. Twenty-four sows were balanced for parity and randomly assigned to 1 of 3 feeding times. Corn-soybean meal-based diet was fed once at: 0730 (Control, T1), 1130 (T2), and 1530 h (T3). Read More

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Incorporating evidence-based behavioral teacher training into Head Start mental health consultation: Description and initial outcomes of a large-scale program.

Psychol Sch 2020 May 5;57(5):735-756. Epub 2020 Feb 5.

National Crime Victims Research and Treatment Center, Medical University of South Carolina, Charleston, South Carolina.

Development of a multicomponent mental health consultation program for a countywide Head Start program is described. The consultation program incorporates strategies from the evidence-based practice, Teacher-Child Interaction Training (TCIT). Through large group professional development trainings before the school year, comprehensive feedback reports based on observations, and in-class coaching via modeling and performance feedback on teachers' use of TCIT skills, the consultation program served 55 Head Start classrooms with 789 children. Read More

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Robenacoxib shows efficacy for the treatment of chronic degenerative joint disease-associated pain in cats: a randomized and blinded pilot clinical trial.

Sci Rep 2021 Apr 8;11(1):7721. Epub 2021 Apr 8.

Translational Research in Pain (TRiP) Program, Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.

The main objective of this pilot clinical trial was to evaluate outcome measures for the assessment of the nonsteroidal anti-inflammatory drug (NSAID) robenacoxib in cats with degenerative joint disease-associated pain (DJD-pain). Otherwise healthy cats (n = 109) with DJD-pain entered a parallel group, randomized, blinded clinical trial. Cats received placebo (P) or robenacoxib (R) for two consecutive 3-week periods. Read More

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Effects of Real-Time Dosimetry on Staff Radiation Exposure in the Cardiac Catheterization Laboratory.

J Invasive Cardiol 2021 Apr 5. Epub 2021 Apr 5.

Lundquist Institute, 1124 West Carson Street, Torrance, CA 90502 USA.

Objectives: Radiation protection is essential for staff of cardiac catheterization laboratories in order to prevent long-term radiation- associated injury and disease. Instant feedback about the actual received dose may help operators to optimize the use of existing shielding devices. Therefore, the current study was designed to investigate whether routine use of real-time dosimetry may be able to reduce staff radiation exposure. Read More

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Characteristics of Veterans With Non-VA Encounters Enrolled in a Trial of Standards-Based, Interoperable Event Notification and Care Coordination.

J Am Board Fam Med 2021 Mar-Apr;34(2):301-308

From the Richard L. Roudebush VA Medical Center, U.S. Department of Veterans Affairs, Indianapolis, IN (RK, BED, ALS, JCY); IU Fairbanks School of Public Health, Indianapolis, IN (BED); Regenstrief Institute, Indianapolis, IN (BED): James J. Peters VA Medical Center, U.S. Department of Veterans Affairs, Bronx, NY (VG, KMJ, KB); Icahn School of Medicine at Mount Sinai, New York, NY (KB).

Introduction: Understanding how veterans use Veterans Affairs (VA) for primary care and non-VA for acute care can help policy makers predict future health care resource use. We aimed to describe characteristics of veterans enrolled in a multisite clinical trial of non-VA acute event notifications and care coordination and to identify patient factors associated with non-VA acute care.

Methods: Characteristics of 565 veterans enrolled in a prospective cluster randomized trial at the Bronx and Indianapolis VA Medical Centers were obtained by interview and chart review. Read More

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Treatment Differences in Primary and Specialty Settings in Veterans with Major Depression.

J Am Board Fam Med 2021 Mar-Apr;34(2):268-290

From the Department of Health Care Policy, Harvard Medical School, Boston, MA (VP-P, HL, HNZ, RCK); the Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY (VP-P); the Center for the Study of Healthcare Innovation, Implementation, and Policy, VA Greater Los Angeles Healthcare System, Los Angeles, CA (LBL); the Division of General Internal Medicine, and Health Services Research, UCLA David Geffen School of Medicine, Los Angeles, CA (LBL); the Department of Behavioral Medicine and Psychiatry, West Virginia University, Morgantown, (RMB); the Center of Excellence for Suicide Prevention, Canandaigua VAMC, Canandaigua, NY (RMB, HL, WRP); the VA Ann Arbor, Center for Clinical Management Research, Ann Arbor, MI (CB, JNK, EPP); the Department of Psychiatry, University of Rochester Medical Center, Rochester, NY (WRP); the Department of Medicine, University of Michigan Medical School, Ann Arbor (EPP); the Cpl Michael J Crescenz VA Medical Center, VISN 4 Mental Illness Research Education and Clinical Center, Philadelphia, PA (DWO); the Perelman School of Medicine, University of Pennsylvania, Philadelphia (DWO).

Introduction: The Veterans Health Administration (VHA) supports the nation's largest primary care-mental health integration (PC-MHI) collaborative care model to increase treatment of mild to moderate common mental disorders in primary care (PC) and refer more severe-complex cases to specialty mental health (SMH) settings. It is unclear how this treatment assignment works in practice.

Methods: Patients (n = 2610) who sought incident episode VHA treatment for depression completed a baseline self-report questionnaire about depression severity-complexity. Read More

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September 2020

Reducing prescribing of benzodiazepines in older adults: a comparison of four physician-focused interventions by a medical regulatory authority.

BMC Fam Pract 2021 Apr 8;22(1):68. Epub 2021 Apr 8.

Research and Evaluation Unit, College of Physicians and Surgeons of Alberta, 10020-100 Street NW, Edmonton, AB, 2700T5J 0N3, Canada.

Background: The inappropriate and/or high prescribing of benzodiazepine and 'Z' drugs (BDZ +) is a major health concern. The purpose of this study was to determine whether physician or pharmacist led interventions or a simple letter or a personalized prescribing report from a medical regulatory authority (MRA) was the most effective intervention for reducing BDZ + prescribing by physicians to patients 65 years of age or older.

Methods: This was a four-armed, one year, blinded, randomized, parallel-group, investigational trial in Alberta, Canada. Read More

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Exenatide Adjunct to Nicotine Patch Facilitates Smoking Cessation and May Reduce Post-Cessation Weight Gain: a Pilot Randomized Controlled Trial.

Nicotine Tob Res 2021 Apr 8. Epub 2021 Apr 8.

Center for Neurobehavioral Research on Addiction, Louis A. Faillace, M.D., Department of Psychiatry and Behavioral Sciences, UTHealth, McGovern Medical School, Houston, TX.

Introduction: Approved pharmacological treatments for smoking cessation are modestly effective, underscoring the need for improved pharmacotherapies. Glucagon-like peptide-1 receptor (GLP-1R) agonists attenuate the rewarding effects of nicotine in preclinical studies. We examined the efficacy of extended-release exenatide, a GLP-1R agonist, combined with nicotine replacement therapy (NRT, patch) for smoking cessation, craving and withdrawal symptoms, with post-cessation body weight as secondary outcome. Read More

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Effects of oxytocin administration and the dog-owner bond on dogs' rescue behavior.

Anim Cogn 2021 Apr 8. Epub 2021 Apr 8.

Consejo Nacional de Investigaciones Científicas y Técnicas, Universidad de Buenos Aires, Instituto de Investigaciones Médicas (IDIM), Grupo de Investigación del Comportamiento en Cánidos (ICOC), Buenos Aires, Argentina.

Rescue behavior is a kind of prosocial response that involves the provision of help to a stressed individual. This behavior has been observed in domestic dogs assisting their owners when they pretended to be trapped. Given the role of the hormone oxytocin as a facilitator for prosocial behavior, we aimed to evaluate the effects of its intranasal administration on the rescue behavior of dogs directed to their owners. Read More

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Correlates of PrEP Uptake Among Young Sexual Minority Men and Transgender Women in New York City: The Need to Reframe "Risk" Messaging and Normalize Preventative Health.

AIDS Behav 2021 Apr 8. Epub 2021 Apr 8.

Center for Health, Identity, Behavior and Prevention Studies (CHIBPS), Rutgers School of Public Health, Newark, NJ, 07102, USA.

Pre-exposure prophylaxis (PrEP) is an effective form of HIV prevention, but young sexual minority men face myriad barriers to PrEP uptake. Participants (n = 202) completed a survey on healthcare experiences and beliefs about HIV and PrEP. While 98% of the sample knew about PrEP, only 23. Read More

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Resource leverage, resource depletion: A multilevel perspective on multiple team membership.

J Appl Psychol 2021 Apr 8. Epub 2021 Apr 8.

Institute for Leadership and Human Resource Management.

Multiple team membership (MTM) is a complex phenomenon that poses significant challenges for organizational research and practice. In this article, we delve into the multilevel nature of MTM, which has not received adequate research attention to date. We develop a resource-based framework that advances our understanding of the antecedents and productivity consequences of firm MTM, and the synergistic effects of individual MTM and firm MTM on an individual's emotional exhaustion. Read More

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Personalized prescriptions of therapeutic skills from patient characteristics: An ecological momentary assessment approach.

J Consult Clin Psychol 2021 Apr 8. Epub 2021 Apr 8.

Department of Psychiatry.

Objective: Rather than relying on a single psychotherapeutic orientation, most clinicians draw from a range of therapeutic approaches to treat their clients. To date, no data-driven approach exists for personalized predictions of which skill domain would be most therapeutically beneficial for a given patient. The present study combined ecological momentary assessment (EMA) and machine learning to test a data-driven approach for predicting patient-specific skill-outcome associations. Read More

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Improving dental-oral health learning in students using a mobile application ("Mytooth"): A controlled before and after study.

Int J Dent Hyg 2021 Apr 8. Epub 2021 Apr 8.

Department of Health Technology Assessment, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Objectives: Tooth decay is one of the most common problems among students. Despite considerable educational interventions, it is still very prevalent. The aim of this study was to compare the effect of a dental-oral health mobile educational application with the common dental-oral health education among the elementary school students. Read More

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Oleoylethanolamide Delays the Dysfunction and Death of Purkinje Cells and Ameliorates Behavioral Defects in a Mouse Model of Cerebellar Neurodegeneration.

Neurotherapeutics 2021 Apr 7. Epub 2021 Apr 7.

Laboratory of Neuronal Plasticity and Neurorepair, Institute for Neurosciences of Castile and Leon (INCyL), University of Salamanca, 37007, Salamanca, Spain.

Oleoylethanolamide (OEA) is an endocannabinoid that has been proposed to prevent neuronal damage and neuroinflammation. In this study, we evaluated the effects of OEA on the disruption of both cerebellar structure and physiology and on the behavior of Purkinje cell degeneration (PCD) mutant mice. These mice exhibit cerebellar degeneration, displaying microtubule alterations that trigger the selective loss of Purkinje cells and consequent behavioral impairments. Read More

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Teachers' gaze over space and time in a real-world classroom.

J Eye Mov Res 2018 Sep 14;13(4). Epub 2018 Sep 14.

Institute for Research in School Education, Masaryk University, Czech Republic.

Reading students' faces and their body language, checking their worksheets, and keeping eye contact is a key trait of teacher competence. The new technology of mobile eye-tracking provides researchers with possibilities to explore teaching from the viewpoint of teacher gaze, but also introduces many new method questions. This study had the primary aim to investigate teachers´ attention distribution over space: the number and durations of several types of their gazes, and how their gaze depends on the factors of students´ gender, achievement, and position in the classroom. Read More

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September 2018

Evaluating Age-Related Variations of Gaze Behavior for a Novel Digitized-Digit Symbol Substitution Test.

J Eye Mov Res 2019 Jun 20;12(1). Epub 2019 Jun 20.

Centre for Cognitive Science, IIT Gandhinagar, India.

Analysis of cognitive functioning from gaze behavior might serve as an early indicator of age related decline of cognitive functions. Standard psychological tests like the digit-symbol substitution test or the symbol-digit modalities test is used exclusively in this regard. In this paper, we have designed and developed a digitized version of the digit symbol substitution test. Read More

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Does Medication Sampling Improve Compliance with Brief Advice? Results from a Pragmatic Randomized Clinical Trial.

J Smok Cessat 2021 16;2021. Epub 2021 Mar 16.

Department of Psychiatry and Behavioral Sciences, MUSC, USA.

Introduction: The 5As model is a standard component of most guidelines for tobacco treatment. Unfortunately, provider adherence to this model is modest.

Aims: Providing physicians with adjunctive tools to adhere to 5As guidelines may serve as a catalyst for brief advice delivery. Read More

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Youths' perceptions of community health workers' delivery of family planning services: a cross-sectional, mixed-methods study in Nakaseke District, Uganda.

BMC Public Health 2021 Apr 7;21(1):666. Epub 2021 Apr 7.

Touro University California, California, USA.

Background: High rates of unintended adolescent pregnancy are a significant health problem in Uganda. To improve access to family planning (FP) services, community-based Village Health Teams (VHTs) are widely employed in Uganda to deliver education and services. However, evaluations of FP programs suggest that mainly older, married women use VHT FP services. Read More

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J Zoo Wildl Med 2021 Apr;52(1):295-299

Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee 37996, USA.

The objective of this study was to determine the pharmacokinetics of a single dose of meloxicam administered subcutaneously (SQ) to three species of sea turtles: loggerheads (), Kemp's ridley (), and greens (). A dose of 1 mg/kg was given to the Kemp's ridleys and greens, whereas the loggerheads received 2 mg/kg. After SQ administration, the half-life (t1/2) of meloxicam administered at 1 mg/kg in the Kemp's ridleys was 5. Read More

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Engineering Z-scheme silver oxide/bismuth tungstate heterostructure incorporated reduced graphene oxide with superior visible-light photocatalytic activity.

J Colloid Interface Sci 2021 Mar 24;596:22-33. Epub 2021 Mar 24.

Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology, School of Chemistry and Chemical Engineering, Guangxi University, Nanning 530005, China. Electronic address:

Photocatalytic degradation of multiple organic contaminants has received extensive research attention and rational design of visible-light driven photocatalyst has been considered as an efficient approach. In this study, a visible-light AgO/BiWO heterostructure incorporated reduced graphene oxide (ABW-RGO) composite photocatalyst was prepared through a facile hydrothermal method for the first time and exhibited synergetic degradation behavior for contaminants in aqueous solutions. Under visible light, Tetracycline antibiotics has degraded 95. Read More

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Bacterial predation transforms the landscape and community assembly of biofilms.

Curr Biol 2021 Apr 1. Epub 2021 Apr 1.

Department of Biological Sciences, Dartmouth College, 78 College Street, Hanover, NH 03755, USA. Electronic address:

The bacterium Bdellovibrio bacteriovorus attaches to the exterior of a Gram-negative prey cell, enters the periplasm, and harvests resources to replicate before lysing the host to find new prey. Predatory bacteria such as this are common in many natural environments, as are groups of matrix-bound prey cell clusters, termed biofilms. Despite the ubiquity of both predatory bacteria and biofilm-dwelling prey, the interaction between B. Read More

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Noninvasive Assessment of Neurodevelopmental Disorders after In Utero Irradiation in Mice: An In Vivo Anatomical and Diffusion MRI Study.

Radiat Res 2021 Apr 7. Epub 2021 Apr 7.

NeuroSpin, Frederic Joliot Institute, Commission for Atomic Energy (CEA), Paris-Saclay University, Gif-sur-Yvette, France.

In utero exposure to ionizing radiation can lead to cerebral alterations during adulthood. Using anatomical magnetic resonance imaging (MRI), it is possible to assess radiation-induced structural brain damage noninvasively. However, little is currently known about microstructure alterations in brain tissue. Read More

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The effects of the ratio of pellets of wheat and barley grains to ground corn grain in the diet on sorting and chewing activities of heat stressed dairy cows.

Vet Med Sci 2021 Apr 7. Epub 2021 Apr 7.

Department of Sustainable Animal Production, Fundamental and Applied Research for Animals and Health, University of Liege, Liege, Belgium.

Background: Normal feeding behaviours is one of the criteria of the health condition of dairy cows particularly in the condition of heat stress.

Objective: The study evaluated the effects of the ratio of pellets of wheat and barley grains to ground corn grain on sorting activity and chewing behaviour of lactating dairy cows managed under ambient conditions including natural heat stress events.

Materials And Methods: Nine multiparous cows (650 ± 56 kg Body Weight; mean ± SD) averaging 102 ± 13 days in milk and producing 54 ± 6 kg/d were randomly assigned to a triplicate 3 × 3 Latin square. Read More

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