332 results match your criteria received 1945


Nonresponder bias in hand surgery: analysis of 1945 cases lost to follow-up over a 6-year period.

J Hand Surg Eur Vol 2021 Sep 16:17531934211045627. Epub 2021 Sep 16.

Queen Margaret Hospital, Dunfermline, UK.

The primary aim of this study was to identify factors associated with nonresponse to routinely collected patient-reported outcome measures (PROMs) after hand surgery. The secondary aim was to investigate the impact of nonresponder bias on postoperative PROMs. We identified 4357 patient episodes for which the patients received pre- and 1-year postoperative questionnaires. Read More

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September 2021

Increasing Hepatitis C Screening in a Federally Qualified Health Center: A Quality Improvement Initiative.

J Healthc Qual 2021 Sep-Oct 01;43(5):312-320

Abstract: Hepatitis C virus (HCV) is a chronic infection that can lead to severe liver damage if left untreated. With increased availability and affordability of curative treatments, screening for HCV has become an important first step in reducing morbidity and mortality. At a rural federally qualified health center in North Carolina, two quality improvement initiatives-an electronic health record (EHR) prompt and educational flyers-were implemented to improve HCV screening rates. Read More

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January 2022

Just "one of so many"? The pathologist Theodor Fahr (1877-1945) and his ambivalent relationship to National Socialism.

Pathol Res Pract 2021 Aug 23;224:153488. Epub 2021 May 23.

Institute for History, Theory and Ethics in Medicine, Medical Faculty, RWTH Aachen University, Wendlingweg 2, Aachen, D-52074, Germany. Electronic address:

Theodor Fahr is well known as a pioneer in renal pathology and the eponym of "Fahr's disease". While his professional merits are undisputed, his relationship to National Socialism remains unclear. On the one hand, he signed the public "oath of allegiance" of German professors to Adolf Hitler, on the other hand, he appeared as a mentor to his Jewish colleague Paul Kimmelstiel. Read More

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Quantifying the incidence of clinically significant respiratory depression in women with and without obesity class III receiving neuraxial morphine for post-cesarean analgesia: a retrospective cohort study.

Int J Obstet Anesth 2021 Aug 7;47:103187. Epub 2021 May 7.

Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, USA.

Background: Obesity is a suspected risk factor for respiratory depression following neuraxial morphine for post-cesarean analgesia, however monitoring guidelines for obese obstetric patients are based on small, limited studies. We tested the hypothesis that clinically significant respiratory depression following neuraxial morphine occurs more commonly in women with body mass index (BMI) ≥40 kg/m compared with BMI <40 kg/m.

Methods: We conducted a single-center, retrospective chart review (2006-2017) of obstetric patients with clinically significant respiratory depression following neuraxial morphine, defined as: (1) opioid antagonist administration; (2) rapid response team activation (initiated in April 2010); or (3) tracheal intubation due to a respiratory event. Read More

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PET-guided eBEACOPP treatment of advanced-stage Hodgkin lymphoma (HD18): follow-up analysis of an international, open-label, randomised, phase 3 trial.

Lancet Haematol 2021 Jun;8(6):e398-e409

German Hodgkin Study Group, Department I of Internal Medicine and Center of Integrated Oncology Aachen, Bonn, Cologne, Düsseldorf, German Hodgkin Study Group, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.

Background: The German Hodgkin Study Group's HD18 trial established the safety and efficacy of PET-guided eBEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone in escalated doses) for the treatment of advanced-stage Hodgkin lymphoma. However, because of a protocol amendment during the enrolment period (June 1, 2011) that changed standard treatment from eight to six cycles, the results of the HD18 trial have been partially immature. We report a prespecified 5-year follow-up analysis of the completed HD18 trial. Read More

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Consolidation Treatment and Long-Term Prognosis of Rituximab in Minimal Change Disease and Focal Segmental Glomerular Sclerosis.

Drug Des Devel Ther 2021 10;15:1945-1953. Epub 2021 May 10.

Department of Nephrology, Ruijin Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, People's Republic of China.

Purpose: There is currently a lack of studies investigating long-term prognosis and the necessity of further rituximab (RTX) consolidation treatment for minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS). The aim of this study was to evaluate the efficacy of RTX for these diseases and to investigate whether a consolidation treatment can lower risks of relapse and reinforce long-term remission.

Patients And Methods: A retrospective study was conducted. Read More

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Behavioral interventions to improve population health outreach for hepatitis C screening: randomized clinical trial.

BMJ 2021 05 18;373:n1022. Epub 2021 May 18.

Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

Objective: To evaluate whether opt out framing, messaging incorporating behavioral science concepts, or electronic communication increases the uptake of hepatitis C virus (HCV) screening in patients born between 1945 and 1965.

Design: Pragmatic randomized controlled trial.

Setting: 43 primary care practices from one academic health system (Philadelphia, PA, USA) between April 2019 and May 2020. Read More

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Massive Transfusion Protocols in Obstetric Hemorrhage: Theory versus Reality.

Am J Perinatol 2021 May 14. Epub 2021 May 14.

Depatment of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas.

Objective:  Massive transfusion protocols are widely implemented in obstetrical practice in case of severe hemorrhage; however, different recommendations exist regarding the appropriate ratios of blood product components to be transfused. We report our extensive experience with massive component transfusion in a referral center in which the standard massive transfusion protocol is modified by ongoing clinical and laboratory evaluation.

Study Design:  A retrospective chart review of all patients who had massive transfusion protocol activation in a level 4 referral center for obstetrical practice was performed from January 2014 to January 2020. Read More

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A cross-sectional study of factors associated with influenza vaccination in Korean cancer survivors.

Eur J Cancer Care (Engl) 2021 Sep 25;30(5):e13443. Epub 2021 Mar 25.

Department of Family Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Objective: To investigate factors associated with influenza vaccination in cancer survivors.

Methods: Study subjects were 1,945 Korean adult cancer survivors. Through medical record review and self-administered questionnaires, social and medical information was collected. Read More

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September 2021

Nationwide treatment and outcomes of perihilar cholangiocarcinoma.

Liver Int 2021 08 12;41(8):1945-1953. Epub 2021 Mar 12.

Department of Surgery, Erasmus MC Cancer Institute, Rotterdam, the Netherlands.

Background: Perihilar cholangiocarcinoma (pCCA) is a rare tumour that requires complex multidisciplinary management. All known data are almost exclusively derived from expert centres. This study aimed to analyse the outcomes of patients with pCCA in a nationwide cohort. Read More

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The Surgical Legacy of Randolph Lee Clark Jr, MD: First Surgeon-in-Chief and Director of University of Texas MD Anderson Cancer Center I. Training and Surgical Practice Before Recruitment to University of Texas MD Anderson Hospital.

Authors:
Charles M Balch

Ann Surg Oncol 2021 Sep 19;28(9):4782-4793. Epub 2021 Jan 19.

Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Dr R. Lee Clark Jr was the first Surgeon-in-Chief and permanent Director of the University of Texas MD Anderson Cancer Hospital, leading the institution from 1946 to 1978. He is known for his visionary leadership as President, but much less about his prodigious activity as a general surgeon and for his academic contributions as a clinical researcher and surgical educator. Read More

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September 2021

The 100 most influential skin cancer publications: a citation analysis.

Dermatol Online J 2020 Nov 15;26(11). Epub 2020 Nov 15.

Rutgers New Jersey Medical School, Newark, NJ.

Background: As skin cancer is the most common cancer in the U.S., many publications focus on cutaneous malignancies. Read More

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November 2020

Hepatitis C Antibody Screening Among Baby Boomers by a Community-Based Health Insurance Company.

Popul Health Manag 2021 Aug 16;24(4):492-495. Epub 2020 Nov 16.

University of Texas at Austin, School of Human Ecology, Public Health Program, Austin, Texas, USA.

Infection with the hepatitis C virus (HCV) is the most commonly reported bloodborne infection in the United States. Individuals born between 1945-1965, the baby boomers, account for approximately 75% of all chronic HCV infections in the United States. The purpose of this study was to determine if a 6-week intervention, including outreach, education, and incentive, by a community-based health insurance company could improve uptake of HCV antibody screening among the 1945-1965 birth cohort. Read More

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A Bibliometric Analysis of Global Scientific Research on Scrub Typhus.

Biomed Res Int 2020 16;2020:5737893. Epub 2020 Oct 16.

Key Laboratory of Environmental Medicine Engineering, Ministry of Education, Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing, 210009 Jiangsu Province, China.

Objective: The rise of zoonotic diseases has become a global health issue around the world. The present study is aimed at assessing the global status and the trends in scrub typhus (ST) research.

Methods: Publications related to ST studies from 1945 to 21 July 2020 were retrieved from the Scopus database. Read More

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Effect of intradialytic progressive resistance exercise on physical fitness and quality of life in maintenance haemodialysis patients.

Nurs Open 2020 11 21;7(6):1945-1953. Epub 2020 Aug 21.

Department of Nursing Longhua Hospital Shanghai University of Traditional Chinese Medicine Shanghai China.

Purpose: To investigate the impact of intradialytic progressive resistance exercise (IPRE) on physical fitness and quality of life in maintenance haemodialysis (MHD) patients.

Methods: Subjects were allocated randomly to the exercise group received IPRE and the control group underwent a haemodialysis session alone. Outcomes measured were including physical fitness ascertained by 6-min walk test, sit-to-stand 10 test and handgrip strength. Read More

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November 2020

Effectiveness of Lifestyle and Drug Intervention on Hypertensive Patients: a Randomized Community Intervention Trial in Rural China.

J Gen Intern Med 2020 12 6;35(12):3449-3457. Epub 2020 Oct 6.

Department of Epidemiology, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, USA.

Background: Strict medication guidance and lifestyle interventions to manage blood pressure (BP) in hypertensive patients are typically difficult to follow.

Objective: To evaluate the 1-year effectiveness of lifestyle and drug intervention in the management of rural hypertensive patients.

Design: Randomized community intervention trial. Read More

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December 2020

A view on the quality of diabetes care in Italy and the role of Diabetes Clinics from the 2018 ARNO Diabetes Observatory.

Nutr Metab Cardiovasc Dis 2020 10 22;30(11):1945-1953. Epub 2020 Aug 22.

CINECA - Interuniversity Consortium, Bologna, Italy.

Backgrounds And Aims: To investigate relevant indicators of quality of care in a large population-based sample of people with diabetes representative of clinical practice in Italy in 2018.

Methods And Results: We analyzed data from 11,300,750 subjects. All administrative healthcare claims collected in 2018 were scrutinized to identify subjects with diabetes and investigate several indicators of quality of care. Read More

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October 2020

Projected Cancer Risks to Residents of New Mexico from Exposure to Trinity Radioactive Fallout.

Health Phys 2020 10;119(4):478-493

Division of Cancer Epidemiology & Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD.

The Trinity nuclear test, conducted in 1945, exposed residents of New Mexico to varying degrees of radioactive fallout. Companion papers in this issue have detailed the results of a dose reconstruction that has estimated tissue-specific radiation absorbed doses to residents of New Mexico from internal and external exposure to radioactive fallout in the first year following the Trinity test when more than 90% of the lifetime dose was received. Estimated radiation doses depended on geographic location, race/ethnicity, and age at the time of the test. Read More

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October 2020

The Methodology Used to Assess Doses from the First Nuclear Weapons Test (Trinity) to the Populations of New Mexico.

Health Phys 2020 10;119(4):400-427

National Cancer Institute, Bethesda, MD.

Trinity was the first test of a nuclear fission device. The test took place in south-central New Mexico at the Alamogordo Bombing and Gunnery Range at 05:29 AM on 16 July 1945. This article provides detailed information on the methods that were used in this work to estimate the radiation doses that were received by the population that resided in New Mexico in 1945. Read More

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October 2020

Estimated Radiation Doses Received by New Mexico Residents from the 1945 Trinity Nuclear Test.

Health Phys 2020 10;119(4):428-477

MeloHill LLC, Rockville, MD.

The National Cancer Institute study of projected health risks to New Mexico residents from the 1945 Trinity nuclear test provides best estimates of organ radiation absorbed doses received by representative persons according to ethnicity, age, and county. Doses to five organs/tissues at significant risk from exposure to radioactive fallout (i.e. Read More

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October 2020

The Likelihood of Adverse Pregnancy Outcomes and Genetic Disease (Transgenerational Effects) from Exposure to Radioactive Fallout from the 1945 Trinity Atomic Bomb Test.

Authors:
John D Boice

Health Phys 2020 10;119(4):494-503

The potential health consequences of the Trinity nuclear weapon test of 16 July 1945 at Alamogordo, New Mexico, are challenging to assess. Population data are available for mortality but not for cancer incidence for New Mexico residents for the first 25 y after the test, and the estimates of radiation dose to the nearby population are lower than the cumulative dose received from ubiquitous natural background radiation. Despite the estimates of low population exposures, it is believed by some that cancer rates in counties near the Trinity test site (located in Socorro County) are elevated compared with other locations across the state. Read More

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October 2020

Current trends in resuscitation for polytrauma patients with traumatic haemorrhagic shock.

Injury 2020 09;51(9):1945-1948

Academic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, United Kingdom; NIHR Leeds Biomedical Research Center, Chapel Allerton Hospital, Leeds, United Kingdom. Electronic address:

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September 2020

Knowledge and risk perception of radiation for Japanese nursing students after the Fukushima Nuclear Power Plant disaster.

Nurse Educ Today 2020 Nov 30;94:104552. Epub 2020 Jul 30.

Department of Oral & Maxillofacial Radiology, Tokushima University of Graduate School, Tokushima, Japan.

Background: The Japanese have had three experiences of radiation disasters: the atomic bombs dropped on Hiroshima and Nagasaki in 1945, and the 2011 Fukushima Nuclear Power Plant disaster. The former two experiences have been covered in compulsory education programs. In light of these incidents, a strong fear of radiation has pervaded people of several generations. Read More

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November 2020

Raymond Allen Weiss (1916-2019).

Am Psychol 2020 Jul-Aug;75(5):735

College of Public Health and Human Sciences.

Presents the obituary of Raymond Allen Weiss (1916-2019). The lion's share of his academic career was spent at NYU (1949 -1981), where Raymond progressed through the faculty ranks, including serving as Department Chair. His academic work was heavily influenced by his military service during World War II, for which Raymond received a commendation for meritorious service in 1945. Read More

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Hepatitis C antibody screening and determinants of initial and duplicate screening in the baby boomer patients of six urban primary care clinics.

PLoS One 2020 9;15(7):e0235778. Epub 2020 Jul 9.

Department of Medicine, Division of Infectious Diseases and HIV Medicine, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America.

Introduction: In 2012, the Centers for Disease Control and Prevention released updated guidelines recommending universal, one-time hepatitis C virus screening for all individuals born between 1945 and 1965. Prior to the implementation of these guidelines, testing rates were inappropriately low, but unnecessary duplicate antibody testing was also problematic. In the era of increased efforts to screen "baby boomers", the prevalence and social determinants of initial and duplicate hepatitis C testing have not been well described. Read More

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September 2020

New Medications Are Needed for Children With Juvenile Idiopathic Arthritis.

Arthritis Rheumatol 2020 11 8;72(11):1945-1951. Epub 2020 Oct 8.

University of Alabama at Birmingham.

Objective: To document the need for additional Food and Drug Administration (FDA)-approved medications for the treatment of juvenile idiopathic arthritis (JIA).

Methods: The electronic medical records of JIA patients treated at Cincinnati Children's Hospital Medical Center (CCHMC) and data from JIA patients enrolled in the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry were included in this study. Unmet medication need was defined in 2 ways: (a) the presence of chronically uncontrolled JIA, defined as a physician global assessment of JIA activity ≥3 (on a 0-10 scale, where 0 = inactive) OR ≥3 joints with active arthritis OR a patient global assessment of well-being ≥3 (on a 0-10 scale, where 0 = very well), despite sequential use of ≥2 biologic disease-modifying antirheumatic drugs (bDMARDs); and (b) the use of ≥1 bDMARD not approved for any JIA category. Read More

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November 2020

Efficacy of intraperitoneally administered paclitaxel for colorectal cancer with peritoneal metastases.

Int J Colorectal Dis 2020 Oct 3;35(10):1945-1949. Epub 2020 Jun 3.

Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.

Purpose: Prognosis after peritoneal metastases in colorectal cancer is worse than that after lung or liver metastases. Previously, we demonstrated the safety of intraperitoneal (ip) administration of paclitaxel (PTX) combined with mFOLFOX6/CapeOX plus bevacizumab for colorectal cancer with peritoneal metastasis in a phase-I trial. Here, we evaluated the efficacy of this chemotherapy. Read More

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October 2020

Political follower or loyal National Socialist? : On the role of former DGP President Herbert Siegmund (1892-1954) in the Third Reich.

Pathologe 2020 May 12. Epub 2020 May 12.

Institut für Geschichte Theorie und Ethik der Medizin, Universitätsklinikum Aachen, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Germany.

Background: Herbert Siegmund (1892-1954) was undoubtedly one of the most influential German pathologists of the 20th century. He received numerous high honors both during the Third Reich and after 1945. He was, among other things, rector of the University of Münster (1943-1945), holder of the Goethe Medal awarded by Hitler (1944), honorary doctor of the University of Cologne (1949), recipient of the Paracelsus Medal (1953), and president of the German Society for Pathology (DGP, 1954). Read More

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Adult outcome after treatment of pediatric posterior fossa ependymoma: long-term follow-up of a single consecutive institutional series of 22 patients with more than 5 years of survival.

J Neurosurg Pediatr 2020 Mar 27:1-5. Epub 2020 Mar 27.

3Radiology, Oslo University Hospital and Faculty of Medicine, University of Oslo, Norway.

Objective: Ependymoma is the third most common posterior fossa tumor in children; however, there is a lack of long-term follow-up data on outcomes after surgical treatment of posterior fossa ependymoma (PFE) in pediatric patients. Therefore, the authors sought to investigate the long-term outcomes of children treated for PFE at their institution.

Methods: The authors performed a retrospective analysis of outcome data from children who underwent treatment for PFE and survived for at least 5 years. Read More

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[Political follower or loyal National Socialist? : On the role of former DGP President Herbert Siegmund (1892-1954) in the Third Reich. German version].

Pathologe 2020 Sep;41(5):523-534

Institut für Geschichte Theorie und Ethik der Medizin, Universitätsklinikum Aachen, RWTH Aachen University, Wendlingweg 2, 52074, Aachen, Deutschland.

Background: Herbert Siegmund (1892-1954) was undoubtedly one of the most influential German pathologists of the 20th century. He received numerous high honors both during the Third Reich and after 1945. He was, among other things, rector of the University of Münster (1943-1945), holder of the Goethe Medal awarded by Hitler (1944), honorary doctor of the University of Cologne (1949), recipient of the Paracelsus Medal (1953), and president of the German Society for Pathology (DGP, 1954). Read More

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September 2020