1,431,548 results match your criteria reaction


Effects of Ultrashort Wave Therapy on Inflammation and Macrophage Polarization after Acute Lung Injury in Rats.

Bioelectromagnetics 2021 Jun 15. Epub 2021 Jun 15.

Rehabilitation Medicine Center, The First Affiliated Hospital of University of South China, Hengyang, People's Republic of China.

Acute lung injury (ALI) features dysregulated pulmonary inflammation. Ultrashort waves (USWs) exert anti-inflammatory effects but no studies have evaluated their activity in ALI. Herein, we used an in vivo lipopolysaccharide (LPS)-induced ALI model to investigate whether the anti-inflammatory activity of USWs is mediated by altering the polarization of M1 to M2 macrophages. Read More

View Article and Full-Text PDF

Long Noncoding RNA GAS5 Targeting miR-221-3p/Cyclin-Dependent Kinase Inhibitor 2B Axis Regulates Follicular Thyroid Carcinoma Cell Cycle and Proliferation.

Pathobiology 2021 Jun 15:1-12. Epub 2021 Jun 15.

Department of Oncology, Xiangya Hospital, Central South University, Changsha, China.

Introduction: Follicular thyroid carcinoma (FTC) is more aggressive than the most common papillary thyroid carcinoma (PTC). However, the current research on FTC is less than PTC. Here, we investigated the effects of long noncoding RNA (lncRNA) GAS5 and miR-221-3p in FTC. Read More

View Article and Full-Text PDF

Hierarchical CoFe LDH/MOF nanorods array with strong coupling effect grown on carbon cloth enables efficient oxidation of water and urea.

Nanotechnology 2021 Jun 15. Epub 2021 Jun 15.

School of Environmental and Chemical Engineering, Shanghai University, Shangda Road 99, Shanghai, 200444, CHINA.

The construction of bifunctional non-noble electrocatalyst for oxygen evolution reaction (OER) and urea oxidation reaction (UOR) is urgent for overall water and urea splitting. Herein, a facile one-step chemical etching- reconstruction strategy is presented for fabricating one-dimensional hierarchical nanorods array composed of CoFe layered double hydroxide (LDH)/MOF supported on carbon cloth as OER and UOR catalysts. By precisely controlling the etching rate, the ligands from Co-MOFs are partially removed, and corresponding metal centers coordinates with hydroxyl ions to generate ultrathin amorphous CoFe LDH nanosheets. Read More

View Article and Full-Text PDF

Nitrogen-carbon materials base on pyrolytic graphene hydrogel for oxygen reduction.

J Colloid Interface Sci 2021 Jun 8;602:274-281. Epub 2021 Jun 8.

Lab of Advanced Nano-structures & Transfer Processes, Department of Chemical Engineering, Tianjin University, Tianjin 300354, China; Chemistry and Chemical Engineering Guangdong Laboratory, Shantou 515031 China. Electronic address:

Hypothesis: Oxygen reduction reaction (ORR) has played a significant role in the utilization of energy nowadays. Nitrogen-doped carbon materials are seen as promising catalysts for ORR, so it is of great significance in studying the functions of different nitrogen moieties.

Experiments: The graphene hydrogel-based nitrogen-arbon materials (GH N-C) were fabricated by first obtaining a gel through hydrothermal treatment using graphene oxide (GO) as precursor, and then calcined in an ammonia atmosphere at different temperatures to form N-doped graphitized materials with divers nitrogen configuration. Read More

View Article and Full-Text PDF

Measurement of the Li(p,p'γ)Li reaction cross-section and 478 keV photon yield from a thick lithium target at proton energies from 0.7 to 1.85 MeV.

Appl Radiat Isot 2021 Jun 9;175:109821. Epub 2021 Jun 9.

Budker Institute of Nuclear Physics, Novosibirsk, Russia; Novosibirsk State University, Novosibirsk, Russia. Electronic address:

The Li (p,p'γ)Li reaction cross section and photon yield from a thick lithium target at proton energies from 0.7 to 1.85 MeV have been measured with a HPGe gamma-ray spectrometer. Read More

View Article and Full-Text PDF

Modification of ordered mesoporous carbon for removal of environmental contaminants from aqueous phase: A review.

J Hazard Mater 2021 May 30;418:126266. Epub 2021 May 30.

College of Environmental Science and Engineering, Yangzhou University, Yangzhou 225127, China; Joint International Research Laboratory of Agriculture and Agri-Product Safety of Ministry of Education of China, Yangzhou University, Yangzhou 225127, Jiangsu, China; Jiangsu Collaborative Innovation Center for Solid Organic Waste Resource Utilization, China. Electronic address:

Contamination of water bodies by potentially toxic elements and organic pollutants has aroused extensive concerns worldwide. Thus it is significant to develop effective adsorbents for removing these contaminants. As a new member of carbonaceous material families (activated carbon, biochar, and graphene), ordered mesoporous carbon (OMC) with larger specific surface area, ordered pore structure, and higher pore volume are being evaluated for their use in contaminant removal. Read More

View Article and Full-Text PDF

Efficient heavy metal removal from water by alginate-based porous nanocomposite hydrogels: The enhanced removal mechanism and influencing factor insight.

J Hazard Mater 2021 Jun 8;418:126358. Epub 2021 Jun 8.

School of Hydraulic Engineering, Changsha University of Science & Technology, Changsha 410114, China; Key Laboratory of Dongting Lake Aquatic Eco-Environmental Control and Restoration of Hunan Province, Changsha 410114, China. Electronic address:

Novel porous alginate-based nanocomposite hydrogels were prepared by incorporating polyaniline-polypyrrole modified graphene oxide ([email protected]) as reinforcing fillers into the alginate matrix ([email protected]/SA) for Cr(VI) and Cu(II) removal from water. Different in-situ co-polymerization functionalized GO with Py-to-An mass ratios of monomers (from nil to 1:1) and contents of [email protected] (from nil to 2.0%(w/v)) were embedded into the alginate backbone to improve the sorption performance. Read More

View Article and Full-Text PDF

A retrospective evaluation of the value of COVID-19 screening and testing in patients with cancer: Aiming at a moving target.

J Infect Public Health 2021 May 26;14(7):949-953. Epub 2021 May 26.

Department of Oncology, King Abdulaziz Medical City, King Abdullah International Medical Research Center, King Saud Bin Abdulaziz University for Health Sciences, Ministry of National Guard Health Affairs (MNGHA), Riyadh, Saudi Arabia.

Background: Diagnosis of COVID-19 infection in cancer patients is critical to co-manage their underlying disease and infection appropriately. Our study aimed at evaluating the sensitivity and specificity of screening patients with cancer for COVID-19 infection.

Methods: All oncology patients receiving care at Department of Oncology at King Abdulaziz Medical City in Riyadh were screened using the acute respiratory infection (ARI) survey. Read More

View Article and Full-Text PDF

Development of highly sensitive one step-PCR tests for improved detection of B. bigemina and B. bovis.

Vet Parasitol 2021 Jun 8;296:109493. Epub 2021 Jun 8.

Instituto de Agrobiotecnología y Biología Molecular (IABIMO) INTA - CONICET, de Los Reseros y Dr. Nicolás Repetto s/n, P.O. Box 25 (B1712WAA), Castelar, Buenos Aires, Argentina.

Bovine babesiosis caused by Babesia bigemina and B. bovis is an economically relevant tick-borne disease distributed over tropical and subtropical world regions. Animals that recover from the clinical disease can remain persistently infected, and those carriers are epidemiologically relevant since they can act as a source of infection to other animals through the tick bite. Read More

View Article and Full-Text PDF

Changes in molecular structure of extracellular polymeric substances (EPS) with temperature in relation to sludge macro-physical properties.

Water Res 2021 May 31;201:117316. Epub 2021 May 31.

School of Environmental Studies, China University of Geosciences, Wuhan 430074, Hubei, China; State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China.

Extracellular polymeric substances (EPS) are important components of activated sludge, whose content and composition have important effects on the macro-physical properties of sludge. In this study, the response of EPS in sludge to temperature (-40-200 °C) was systematically investigated using XAD resin fractionation, variable-temperature infrared spectra (VTIS) and two-dimensional correlation spectroscopy (2D-COS). The relationships between the molecular structure of EPS and the macro-physical properties (rheological property and dewatering performance) of waste activated sludge (WAS) at varying temperature were also established. Read More

View Article and Full-Text PDF

Metabolic and conformational stabilization of a VEGF-mimetic beta-hairpin peptide by click-chemistry.

Eur J Med Chem 2021 May 26;222:113575. Epub 2021 May 26.

Istituto di Scienze e Tecnologie Chimiche "Giulio Natta", CNR, Via M. Bianco 9, 20131, Milano, Italy. Electronic address:

HPLW is a Vascular Endothelial Growth Factor (VEGF)-mimicking beta-hairpin peptide endowed of proangiogenic effect and showing valuable biomedical application in the proangiogenic therapy. However, the translational potential of HPLW is limited by its low metabolic stability, which would shorten the in vivo efficacy of the molecule. Here, we developed a peptide analog of HPLW, named HPLW2, that retains the structural and biological properties of the original peptide but features an impressive resistance to degradation by human serum proteases. Read More

View Article and Full-Text PDF

In vivo evaluation of deer antler trabecular bone as a reconstruction material for bone defects.

Res Vet Sci 2021 Jun 11;138:116-124. Epub 2021 Jun 11.

Department of Clinical Sciences, FARAH, Faculty of Veterinary Medicine, University of Liège, Quartier Vallée 2, Avenue de Cureghem 1 - B67, Liège, Belgium.

Availability of graft materials to fill up osseous defects has always been a concern in orthopaedic surgeries. Deer antler material is a primary bone structure that is easy to collect and could serve as a xenograft. This study examines the behaviour of red deer antler trabecular cylinders in critical size distal femoral epiphyseal defects in 11 rabbits, and evaluates the effect of the decellularization protocols. Read More

View Article and Full-Text PDF

Propofol represses cell growth and metastasis by modulating the circNCAPG/miR-200a-3p/RAB5A axis in glioma.

World Neurosurg 2021 Jun 12. Epub 2021 Jun 12.

Department of Anesthesiology, The First Hospital of Hebei Medicine University, Shijiazhuang, Hebei,050011, P.R. China. Electronic address:

Background: Glioma is a common primary intracranial tumor, with high infiltration and aggression. Propofol (Pro) is associated with growth and metastasis in glioma. Meanwhile, circular RNA non-SMC condensin I complex subunit G (circNCAPG, hsa_circ_0007244) has been reported to be upregulated in glioma. Read More

View Article and Full-Text PDF

Coronavirus Disease-2019 (COVID-19) and Pituitary Apoplexy: A Single-Center Case Series and Review of the Literature.

World Neurosurg 2021 Jun 12. Epub 2021 Jun 12.

Departments of Neurosurgery(,) University of Mississippi Medical Center, Jackson, MS, United States.

Background: Pituitary apoplexy (PA) is a rare but life-threatening condition characterized by pituitary infarction and hemorrhage, most often in the setting of a preexisting adenoma. The risk factors and mechanisms associated with PA are poorly understood. Although neurovascular manifestations of coronavirus disease-19 (COVID-19) infection have been documented, its association with PA is to be determined. Read More

View Article and Full-Text PDF

Deeply Mining a Universe of Peptides Encoded by Long Noncoding RNAs.

Mol Cell Proteomics 2021 Jun 12:100109. Epub 2021 Jun 12.

Laboratory of Protein and Peptide Pharmaceuticals & Laboratory of Proteomics, institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:

Many small open reading frames (smORFs) embedded in lncRNA transcripts have been shown to encode biologically functional polypeptides (smORFs-encoded polypeptides, SEPs) in different organisms. Despite significant advances in genomics, bioinformatics and proteomics that largely enabled the discovery of novel SEPs, their identification across different biological samples is still hampered by their poor predictability, diminutive size and low relative abundance. Here, we take advantage of NONCODE, a repository containing the most complete collection and annotation of lncRNA transcripts from different species, to build a novel database that attempts to maximize a collection of SEPs from human and mouse lncRNA transcripts. Read More

View Article and Full-Text PDF

Interleukin 4 and Interleukin 4 receptor alpha gene variants and risk of atopy - A case control study based assessment.

Clin Immunol 2021 Jun 12:108783. Epub 2021 Jun 12.

Department of Clinical Biochemistry, Sher-I-Kashmir Institute of Medical Sciences (SKIMS), Soura, 190011, J&K, India. Electronic address:

Introduction: IL4 pathway is known to upregulate IgE mediated immune responses and responsible for the manifestation of Atopic disorders. The current study was aimed to elucidate the genetic variations of Interleukin 4 (IL4) and Interleukin 4 receptor alpha (IL4R) genes and their possible association with atopic subjects.

Methods: The well-designed questionnaire was used to collect the subject demographic and clinical details. Read More

View Article and Full-Text PDF

Beta2-microglobulin(B2M) in cancer immunotherapies: Biological function, resistance and remedy.

Cancer Lett 2021 Jun 12. Epub 2021 Jun 12.

The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School & Clinical Cancer Institute of Nanjing University, Nanjing, 210008, China. Electronic address:

Cancer immunotherapies have made much headway during the past decades. Techniques including the immune checkpoint inhibition (ICI) and adoptive cell therapy (ACT) have harvested impressive efficacy and provided far-reaching tools for treating cancer patients. However, due to inadequate priming of the immune system, a certain subgroup of patients remains resistant to cancer immunotherapies during or after the treatment. Read More

View Article and Full-Text PDF

Highly efficient uranium (VI) capture from aqueous solution by means of a hydroxyapatite-biochar nanocomposite: Adsorption behavior and mechanism.

Environ Res 2021 Jun 12:111518. Epub 2021 Jun 12.

Guangdong Provincial Key Laboratory for Radionuclides Pollution Control and Resources, School of Environmental Science and Engineering, Guangzhou University, Guangzhou, 510006, China; School of Civil Engineering, Guangzhou University, Guangzhou, 510006, PR China. Electronic address:

The exploration and rational design of easily separable and highly efficient sorbents with the sufficient capability of retaining radioactive and toxic uranium U(VI) is paramount. In this study, a hydroxyapatite (HAP) biochar nanocomposite (BR/HAP) was successfully fabricated from rice straw biochar (BR), to be used as a new and efficient adsorbent for removing U(VI) from aqueous solution. Both BR and the BR/HAP composite were characterized via Brunauer-Emmett-Teller (BET), scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), transmission electron microscopy (TEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) and X-ray photo electron spectroscopy (XPS) techniques. Read More

View Article and Full-Text PDF

Intraspecific variations of the cytoplasmic male sterility genes and in Brassica maurorum and Moricandia arvensis, and the specificity of the mRNA processing.

Genome 2021 Jun 15. Epub 2021 Jun 15.

Dept. Biotech., Fac. Eng., Kyoto Sangyo Univ., Motoyama, Kamigamo, Kyoto, Kyoto, Japan, 603-8555;

The mitochondrial gene co-transcribed with and causes cytoplasmic male sterility in crops, is widely distributed across wild species and genera of . However, intraspecific variations in the presence of have not yet been studied, and the mechanisms for the wide distribution of the gene remain unclear. We analyzed the presence and sequence variations of in two wild species, and . Read More

View Article and Full-Text PDF

Efficient and effective single-step screening of individual samples for SARS-CoV-2 RNA using multi-dimensional pooling and Bayesian inference.

J R Soc Interface 2021 Jun 16;18(179):20210155. Epub 2021 Jun 16.

Department of Chemistry, University of Utah, Salt Lake City, UT, USA.

Rapid and widespread implementation of infectious disease surveillance is a critical component in the response to novel health threats. Molecular assays are the preferred method to detect a broad range of viral pathogens with high sensitivity and specificity. The implementation of molecular assay testing in a rapidly evolving public health emergency, such as the ongoing COVID-19 pandemic, can be hindered by resource availability or technical constraints. Read More

View Article and Full-Text PDF

Localized Cutaneous Reaction to a mRNA COVID-19 Vaccine.

J Cosmet Dermatol 2021 Jun 15. Epub 2021 Jun 15.

Department of Dermatology, Wayne State University, Detroit, Michigan, USA.

The corona virus disease (COVID-19) is a novel disease that can lead to fatal outcomes in infected individuals. Messenger RNA (mRNA) vaccines are two of the three Food and Drug Administration (FDA) approved vaccines in the United States (US) to date. Disclosed side effects by the Centers for Disease Control and Prevention (CDC) included tiredness, headache, muscle pain, chills, fever, and nausea. Read More

View Article and Full-Text PDF

Salen-decorated Periodic Mesoporous Organosilica: from metal-assisted epoxidation to metal-free CO2 insertion.

Chem Asian J 2021 Jun 15. Epub 2021 Jun 15.

Universiteit Gent, Department of Inorganic and Physical Chemistry, Krijgslaan 281, Building S3, 9000, Ghent, BELGIUM.

We clicked a salen ligand onto a thiol-ethane bridged periodic mesoporous organosilica (Salen-PMO) using a photo-initiated thiol-ene click reaction. This process resulted in a covalently bonded salen ligand on the PMO material. The final BET surface area amounts 511 m 2 /g and the pore size diameter is approximately 5. Read More

View Article and Full-Text PDF

Risks and mitigation strategies to prevent etoposide infusion-related reactions in children.

Pharmacotherapy 2021 Jun 15. Epub 2021 Jun 15.

Department of Pediatrics, Children's Mercy Hospital and the University of Missouri-Kansas City.

Etoposide is an antineoplastic agent widely used for treatment of many pediatric cancers. Etoposide has been associated with infusion-related reactions. In this brief report we compare etoposide infusion-related reactions that occurred over a 10-year period at two freestanding pediatric hospitals. Read More

View Article and Full-Text PDF

Visible-Light Photocatalytic Oxidation of DMSO for RAFT Polymerization.

Photochem Photobiol 2021 Jun 15. Epub 2021 Jun 15.

University of Maryland, Department of Chemistry and Biochemistry, College Park, MD, USA, 20942.

The solvent is an important, yet often forgotten part of a reaction mechanism. Many photochemical polymerizations are carried out using dimethyl sulfoxide (DMSO) as a way to promote the solubility of both the reactants and products, but its reactivity is rarely considered when initiation mechanisms are proposed. Herein, the oxidation of DMSO by an excited state quinone is used to form initiating radicals resulting in the polymerization of methacrylate monomers, and the polymerization can be controlled with the addition of a chain transfer agent. Read More

View Article and Full-Text PDF

Regularity detection under stress: Faster extraction of probability-based regularities.

PLoS One 2021 15;16(6):e0253123. Epub 2021 Jun 15.

Institute of Psychology, ELTE Eötvös Loránd University, Budapest, Hungary.

Acute stress can crucially influence learning and memory processes. One of the key processes underlying human learning and memory is the ability of our brain to rapidly detect and extract regularities from sensory input across time and space leading to effective predictive processing. Here, we aimed to get an in-depth look into the effect of stress on the acquisition of two aspects of regularity extraction. Read More

View Article and Full-Text PDF

Molecular investigation of tick-borne pathogens in ticks removed from tick-bitten humans in the southwestern region of the Republic of Korea.

PLoS One 2021 15;16(6):e0252992. Epub 2021 Jun 15.

Department of Internal Medicine, College of Medicine, Chosun University, Gwangju, Republic of Korea.

In this study, we investigated the presence of tick-borne pathogens in ticks removed from tick-bitten humans in the southwestern provinces of the Republic of Korea (ROK). We identified 33 ticks from three tick species, namely Amblyomma testudinarium (60.6%), Haemaphysalis longicornis (27. Read More

View Article and Full-Text PDF

Laboratory evaluation of the rapid diagnostic tests for the detection of Vibrio cholerae O1 using diarrheal samples.

PLoS Negl Trop Dis 2021 Jun 15;15(6):e0009521. Epub 2021 Jun 15.

Division of Bacteriology, ICMR-National Institute of Cholera and Enteric Diseases, Kolkata, India.

Background: Cholera, an acute diarrheal disease is a major public health problem in many developing countries. Several rapid diagnostic tests (RDT) are available for the detection of cholera, but their efficacies are not compared in an endemic setting. In this study, we have compared the specificity and sensitivity of three RDT kits for the detection of Vibrio cholerae O1 and compared their efficiency with culture and polymerase chain reaction (PCR) methods. Read More

View Article and Full-Text PDF

Designing microbial communities to maximize the thermodynamic driving force for the production of chemicals.

PLoS Comput Biol 2021 Jun 15;17(6):e1009093. Epub 2021 Jun 15.

Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany.

Microbial communities have become a major research focus due to their importance for biogeochemical cycles, biomedicine and biotechnological applications. While some biotechnological applications, such as anaerobic digestion, make use of naturally arising microbial communities, the rational design of microbial consortia for bio-based production processes has recently gained much interest. One class of synthetic microbial consortia is based on specifically designed strains of one species. Read More

View Article and Full-Text PDF

Removal of triclosan from water by sepiolite supported bimetallic Fe/Ni nanoparticles.

Environ Technol 2021 Jun 15:1-10. Epub 2021 Jun 15.

Institute of Environmental pollution and health, School of Environmental and Chemical Engineering, Shanghai University, Shanghai, People's Republic of China.

A simple and low-cost route to fabricate sepiolite-supported bimetallic Fe/Ni (Sep-Fe/Ni) nanoparticles was obtained by synchronous liquid phase reduction method. The as prepared composite was used to remove triclosan (TCS) from aqueous solutions. X-ray diffraction, scanning electron microscopy, transmission electron microscopy, and Brunauer-Emmett-Teller (BET) analysis were used for characterization of the materials. Read More

View Article and Full-Text PDF

First Report of Brown Spot Needle Blight on Pinus thunbergii Parl. Caused by Aureobasidium pullulans in China.

Plant Dis 2021 Jun 15. Epub 2021 Jun 15.

Nanjing Forestry University, 74584, College of Forestry, 159 Longpan Road, Nanjing, China, 210037;

Pinus thunbergii Parl., known as black pine, is widely distributed all over China. This pine variety can prevent soil desertification and promote soil conservation and is excellent for constructing fast-growing forests and shelter belts. Read More

View Article and Full-Text PDF