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Systemic paralogy and function of retinal determination network homologs in arachnids.

BMC Genomics 2020 Nov 23;21(1):811. Epub 2020 Nov 23.

Department of Integrative Biology, University of Wisconsin-Madison, Madison, WI, 53706, USA.

Background: Arachnids are important components of cave ecosystems and display many examples of troglomorphisms, such as blindness, depigmentation, and elongate appendages. Little is known about how the eyes of arachnids are specified genetically, let alone the mechanisms for eye reduction and loss in troglomorphic arachnids. Additionally, duplication of Retinal Determination Gene Network (RDGN) homologs in spiders has convoluted functional inferences extrapolated from single-copy homologs in pancrustacean models. Read More

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November 2020
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