12,058 results match your criteria ratesmethods ninety-nine


Children are safe in schools: a review of the Irish experience of reopening schools during the COVID-19 pandemic.

Public Health 2021 Jun 12;195:158-160. Epub 2021 Jun 12.

Office of the Clinical Director for Health Protection, HSE, Ireland; Department of Public Health, HSE Midlands, Tullamore, Ireland.

Objectives: Schools in the Republic of Ireland reopened to students and staff in late August 2020. We sought to determine the test positivity rate of close contacts of cases of coronavirus disease 2019 (COVID-19) in schools during the first half-term of the 2020/2021 academic year.

Methods: National-level data from the schools' testing pathway were interrogated to determine the positivity rate of close contacts of cases of COVID-19 in Irish primary, postprimary and special schools during the first half-term of 2020/2021 academic year. Read More

View Article and Full-Text PDF

Selection of lactic acid bacteria with promising probiotic aptitudes from fruit and ability to survive in different food matrices.

Braz J Microbiol 2021 Jun 14. Epub 2021 Jun 14.

Laboratório de Microbiologia de Alimentos, Departamento de Nutrição, Centro de Ciências da Saúde, Universidade Federal da Paraíba, Campus I, João Pessoa, Paraíba, Brazil.

Lactic acid bacteria (LAB) are among the most prevalent microorganisms forming the autochthonous microbiota of fruit. This study aimed to select LAB isolates with probiotic aptitudes from apple, banana, grape, and orange through evaluation of in vitro safety, technological, and functional-related properties. The ability of most promising selected isolates to survive in commercial apple and orange juice, meat stew, vegetable puree, and UHT milk during 28 days of refrigeration storage was evaluated. Read More

View Article and Full-Text PDF

Outcomes of pregnancy and delivery in women with continent lower urinary tract reconstruction: systematic review of the literature.

Int Urogynecol J 2021 Jun 14. Epub 2021 Jun 14.

Department of Urology, CHU-Université de Nantes, 1 place Alexis Ricordeau, 44000, Nantes, France.

Introduction And Hypothesis: The aim of this systematic review of the literature was to pool all the existing data regarding pregnancy and delivery in women with neurogenic bladder or bladder exstrophy who had undergone previous lower urinary tract reconstruction (LUTR).

Methods: We conducted a systematic review of the literature from PubMed/MedLine, ClinicalTrials.gov and the Google Scholar database, from 1972 to July 2020. Read More

View Article and Full-Text PDF

Development and implementation of a novel Web-based gaming application to enhance emergency medical technician knowledge in low- and middle-income countries.

AEM Educ Train 2021 Jul 6;5(3):e10602. Epub 2021 May 6.

Department of Emergency Medicine Stanford University Stanford California USA.

Background: Increasing access to high-quality emergency and prehospital care is an important priority in low- and middle-income countries (LMICs). However, ensuring that emergency medical technicians (EMTs) maintain their clinical knowledge and proficiency with procedural skills is challenging, as continuing education requirements are still being introduced, and clinical instructional efforts need strengthening. We describe the development and implementation of an innovative asynchronous learning tool for EMTs in the form of a Web-based trivia game. Read More

View Article and Full-Text PDF

Post-partum Hospital Stay and Mothers' Choices on Breastfeeding and Vaccines: A Chance We Should Not Miss.

Front Public Health 2021 28;9:625779. Epub 2021 May 28.

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, NICU, Milan, Italy.

Parents' education and knowledge regarding major topics of children's health, such as nutrition and vaccines, have a paramount role. However, breastfeeding rates in first year of life are lower than recommended, and vaccine hesitancy is progressively spreading. To reverse this harmful trend, healthcare professionals are challenged to promote correct health information. Read More

View Article and Full-Text PDF

Safety and Efficacy of Short-Course Intravenous Antibiotics after Complicated Appendicitis in Selected Patients.

Acta Chir Belg 2021 Jun 12:1-15. Epub 2021 Jun 12.

Colorectal Unit, Department of Surgery, Flinders Medical Centre, Adelaide, Australia.

Background: After surgery for complicated appendicitis (CA), common practice is to treat all patients with a standardised long-course of intravenous antibiotics (IVAB) to reduce the risk of postoperative surgical infections (PSI). The aim of the current study was to evaluate the safety and efficacy of a short-course IVAB after CA in selected patients.

Methods: The Department's prospectively collected database identified CA patients treated between2015 and 2019. Read More

View Article and Full-Text PDF

Multiple drilling is not effective in reducing the rate of conversion to Total hip Arthroplasty in early-stage nontraumatic osteonecrosis of the femoral head: a case-control comparative study with a natural course.

BMC Musculoskelet Disord 2021 Jun 12;22(1):535. Epub 2021 Jun 12.

Department of Orthopedic Surgery, West China Hospital, West China Medical School, Sichuan University, #37 Guoxue Road, Chengdu, Sichuan Province, 610041, People's Republic of China.

Background: To determine whether multiple drilling is effective in postponing the need for total hip arthroplasty (THA) in early-stage nontraumatic osteonecrosis of the femoral head (ONFH).

Methods: We identified 514 patients who were diagnosed with early-stage ONFH between January 2008 and December 2018. One hundred ninety-six patients underwent multiple drilling, and 318 patients had a natural course of progression. Read More

View Article and Full-Text PDF

Incidence and Risk Factors of Corneal Endothelial Failure after Phacoemulsification in Patients with Fuchs Endothelial Corneal Dystrophy: A 13-Year Retrospective Cohort.

Clin Ophthalmol 2021 4;15:2367-2373. Epub 2021 Jun 4.

Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Objective: To evaluate the incidence of corneal endothelial failure (CEF) and determine the risk factors of developing CEF after phacoemulsification in patients with Fuchs endothelial corneal dystrophy (FECD).

Methods: A retrospective chart review of 2873 patients who underwent phacoemulsification with intraocular lens (IOL) implantation was conducted at Ramathibodi Hospital, Bangkok, Thailand from January 2007 to December 2019. Patient baseline characteristics, underlying diseases, levels of nuclear cataract, pre-operative specular microscopic parameters, intraoperative information (cumulative dissipated energy [CDE], mode of phacoemulsification, and complications), and occurrence of CEF were collected. Read More

View Article and Full-Text PDF

The role of combination therapy in the treatment of severe infections caused by carbapenem resistant gram-negatives: a systematic review of clinical studies.

BMC Infect Dis 2021 Jun 9;21(1):545. Epub 2021 Jun 9.

Division of Infectious Diseases, Department of Diagnostic and Public Health, University of Verona, P.Le L.A. Scuro 10, 37134, Verona, Italy.

Background: Effective treatment of sepsis due to carbapenem-resistant Gram-negative bacteria (CR-GNB) remains a challenge for clinicians worldwide. In recent years, the combination of antibiotics has become the preferred treatment strategy for CR-GNB infection. However, robust evidence to support this approach is lacking. Read More

View Article and Full-Text PDF

Feasibility and safety of a rapid-access transient ischemic attack clinic.

J Am Assoc Nurse Pract 2021 Jun 7. Epub 2021 Jun 7.

Center for Health Care Improvement Science, Virginia Mason Franciscan Health, Seattle, Washington Stanford University, Palo Alto, California Virginia Mason Franciscan Health, Seattle, Washington.

Background: In the United States, patients with transient ischemic attacks (TIAs) are commonly admitted to the hospital despite evidence that low-risk TIA patients achieve improved outcomes at lower costs at specialized rapid-access TIA clinics (RATCs).

Local Problem: All patients experiencing TIAs at a hospital system in the Pacific Northwest were being admitted to the hospital. This project aimed to implement an RATC to relocate care for low-risk TIA patients, showing feasibility and safety. Read More

View Article and Full-Text PDF

A Systematic Review of the Biological Correlates and Consequences of Childhood Maltreatment and Adverse Childhood Experiences.

Trauma Violence Abuse 2021 Jun 9:15248380211021613. Epub 2021 Jun 9.

School of Criminal Justice, 2514University of Cincinnati, OH, USA.

Childhood maltreatment (CM) and adverse childhood experiences (ACEs) are two primary forms of interpersonal victimization that have been associated with a host of deleterious health outcomes. Studies over the past decade have begun to use a range of biologically informed methods to better understand the role biology plays in the relationship between CM, ACEs, and later life outcomes. This line of research has shown that both forms of victimization occur at sensitive periods of development, which can increase the likelihood of "getting under the skin" and influence health and behavior across the life course. Read More

View Article and Full-Text PDF

Remote screening of diabetic retinopathy using ultra-widefield retinal imaging.

Diabetes Res Clin Pract 2021 Jun 5:108902. Epub 2021 Jun 5.

Nagoya City University Graduate School of Medical Sciences, Nagoya City University Graduate School of Medical Sciences 1 Kawasumi, Mizuho-cho, Mizuho-ku Nagoya, Aichi, 467-8601, Japan. Electronic address:

Aims: To study the possibility of constructing a remote interpretation system for retinal images.

Methods: An ultra-widefield (UWF) retinal imaging device was installed in the internal medicine department specializing in diabetes to obtain fundus images of patients with diabetes. Remote interpretation was conducted at Nagoya City University using a cloud server. Read More

View Article and Full-Text PDF

UK IBD Twin Registry: Concordance and Environmental Risk Factors of Twins with IBD.

Dig Dis Sci 2021 Jun 7. Epub 2021 Jun 7.

Department of Gastroenterology, Royal London Hospital, Whitechapel Rd, Whitechapel, London, E1 1FR, UK.

Background And Aims: Twin studies have long been used to infer heritability. Within the 'omics era, twin cohorts have even greater research potential. This study describes the formation of the UK IBD Twin Registry and analysis of concordance and environmental factors. Read More

View Article and Full-Text PDF

Changing Results to Change Results: Nudging Antimicrobial Prescribing for .

Open Forum Infect Dis 2021 Jun 16;8(6):ofaa605. Epub 2020 Dec 16.

University of Toronto, Faculty of Medicine, Toronto, Ontario, Cananda.

Background: Patients who test positive for by polymerase chain reaction (PCR), with a negative toxin enzyme immunoassay (EIA), are commonly colonized and do not require treatment. However, clinicians often treat based on a positive PCR result regardless of the toxin EIA result. We evaluated the clinical impact of a microbiology reporting nudge, changing from a report that included both assay results along with treatment recommendations to one that suggested clinicians consider colonization or early infection. Read More

View Article and Full-Text PDF

Perioperative Exercise Intention and Influencing Factors: A Multi-Centered Cross-Sectional Study.

Front Public Health 2021 20;9:653055. Epub 2021 May 20.

Department of Anesthesiology, Youyang Hospital, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

This study aimed to evaluate the level and factors affecting the perioperative exercise intention in China. This study was a cross-sectional survey in Southwest China. Four hundred and ninety nine participants were randomly sampled in eight medical centers from November 23, 2020 to November 27, 2020. Read More

View Article and Full-Text PDF

The transverse musculocutaneous gracilis flap for autologous breast reconstruction: focus on donor site morbidity.

Breast Cancer 2021 Jun 6. Epub 2021 Jun 6.

Department of Hand, Plastic and Reconstructive Surgery, Microsurgery, Burn Center, BG Trauma Center Ludwigshafen, Hand and Plastic Surgery, University of Heidelberg, Ludwigshafen, Germany.

Purpose: The transverse musculocutaneous gracilis (TMG) flap is as a valuable alternative in autologous breast reconstruction. The purpose of this study was to evaluate the donor site morbidity and secondary refinement procedures after TMG flap breast reconstruction.

Methods: A retrospective study was conducted, including all patients who received TMG flap breast reconstructions, from January 2012 to August 2019. Read More

View Article and Full-Text PDF

A children's epilepsy diagnosis aid: Development and early validation using a Bayesian approach.

Epilepsy Behav 2021 Jun 3;121(Pt A):108062. Epub 2021 Jun 3.

Visiting Professor of Neurology at Faculty of Medicine -University Of Khartoum, Sudan.

Introduction: The diagnosis of epilepsy in children is difficult and misdiagnosis rates can be as much as 36%. Diagnosis in all countries is essentially clinical, based on asking a series of questions and interpreting the answers. Doctors experienced enough to do this are either scarce or absent in very many parts of the world so there is a need to develop a diagnostic aid to help less-experienced doctors or non-physician health workers (NPHWs) do this. Read More

View Article and Full-Text PDF

Preoperative and Intraoperative Blood Pressure Variability Independently Correlate With Outcomes.

J Surg Res 2021 Jun 1;266:387-397. Epub 2021 Jun 1.

University of North Dakota School and Medicine and Health Sciences, Grand Forks, North Dakota; University of North Dakota, Grand Forks, North Dakota; University of North Dakota School of Medicine and Health Sciences, Grand Forks, North Dakota. Electronic address:

Background: Blood pressure variability (BPV) describes visit-to-visit blood pressure (BP) changes independent of hypertension. Preoperative BPV and intraoperative BPV are associated with increased postoperative outcomes. We investigated the impact of both preoperative BPV and intraoperative BPV on elective surgical outcomes, specifically whether preoperative BPV and intraoperative BPV were independent risk factors for surgical complications. Read More

View Article and Full-Text PDF

The Bristow-Latarjet Procedure for Revision of Failed Arthroscopic Bankart: A retrospective case series of 59 consecutive patients.

J Shoulder Elbow Surg 2021 Jun 1. Epub 2021 Jun 1.

ICR - Institut de Chirurgie Réparatrice - Locomoteur & Sport, 7 av Durante, 06000 Nice, France. Electronic address:

Background: Recurrence of anterior instability after arthroscopic Bankart prevents return to sport and remains a surgical challenge.

Aim: To assess clinical and radiological outcomes after coracoid bone-block performed either open or under arthroscopy, for the management of failed arthroscopic Bankart.

Patients And Methods: fifty-nine consecutive patients with anterior instability recurrence after arthroscopic Bankart were revised with a Bristow or Latarjet procedure performed either open (25 cases) or under arthroscopy (34 cases). Read More

View Article and Full-Text PDF

Diffusion tensor imaging reveals greater microstructure damage in lesional tissue that shrinks into cerebrospinal fluid in multiple sclerosis.

J Neuroimaging 2021 Jun 3. Epub 2021 Jun 3.

Buffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, New York, USA.

Background And Purpose: Atrophied T2 lesion volume (LV), reflecting the complete transformation of lesions into cerebrospinal fluid (CSF), has been associated with disease progression in multiple sclerosis (MS). The underlying damage leading to lesion destruction remains poorly understood. The objective of this study was to use diffusion tensor imaging (DTI) to investigate the extent of microstructural tissue damage at baseline in lesions that subsequently transform into CSF. Read More

View Article and Full-Text PDF

Virtually Serving the Underserved: Resident Perceptions of Telemedicine Use While Training During Coronavirus Disease 2019.

Telemed J E Health 2021 Jun 1. Epub 2021 Jun 1.

Department of Internal Medicine, Morehouse School of Medicine, Atlanta, Georgia, USA.

To adapt during the coronavirus disease 2019 (COVID-19) pandemic, a large safety-net hospital in Atlanta, Georgia and other hospitals across the United Sates, increased telemedicine (TM) for outpatient visits. The impact on resident physicians, including minority providers, had not yet been reported. We aimed to assess how primary care residents perceived increased TM in clinics during the pandemic, and assess resident burnout. Read More

View Article and Full-Text PDF

Ga-PSMA-PET screening and transponder-guided salvage radiotherapy to the prostate bed alone for biochemical recurrence following prostatectomy: interim outcomes of a phase II trial.

World J Urol 2021 Jun 2. Epub 2021 Jun 2.

Epworth HealthCare, Richmond, VIC, Australia.

Purpose: To evaluate outcomes for men with biochemically recurrent prostate cancer who were selected for transponder-guided salvage radiotherapy (SRT) to the prostate bed alone by Ga-labelled prostate-specific membrane antigen positron emission tomography (Ga-PSMA-PET).

Methods: This is a single-arm, prospective study of men with a prostate-specific antigen (PSA) level rising to 0.1-2. Read More

View Article and Full-Text PDF

Predictors of complications in initially haemodynamically stable patients admitted in a modern coronary care unit.

J Cardiovasc Med (Hagerstown) 2021 Jul;22(7):553-559

Department of Cardiology, Intensive Cardiac Care Unit, Ruggi D' Aragona Hospital.

Aims: Resource optimization in the intensive cardiac care unit (ICCU) is, nowadays, of great importance because of the increasing number of acute cardiovascular patients requiring high-intensity level-of-care. Because of natural limits in ICCU bed availability, understanding, which patients will really benefit from in a such a critical care setting, is of paramount importance. In our study, we analysed a heterogeneous ICCU population with initially stable haemodynamic conditions, in order to find potential predictors of severe complications. Read More

View Article and Full-Text PDF

Assessing operating theatre efficiency: A prospective cohort study to identify intervention targets to improve efficiency.

ANZ J Surg 2021 Jun 1. Epub 2021 Jun 1.

Division of Surgery, Northern Health, Epping, Australia.

Background: Operating theatre efficiency is critical to providing optimum healthcare and maintaining the financial success of a hospital. This study aims to assess theatre efficiency, with a focus on staff activities, theatre utilisation and case changeover.

Methods: Theatre efficiency data were collected prospectively at a single centre in metropolitan Melbourne, Australia, over two 5-week periods. Read More

View Article and Full-Text PDF

Bikini Incision Increases the Incidence of Lateral Femoral Cutaneous Nerve Injury in Direct Anterior Approach Hip Arthroplasty: A Prospective Ultrasonic, Electrophysiological, and Clinical Study.

J Arthroplasty 2021 May 15. Epub 2021 May 15.

Department of Joint Surgery, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, China.

Background: Lateral femoral cutaneous nerve (LFCN) injury has been widely reported as one of the most common complications of direct anterior approach (DAA) hip arthroplasty. Bikini incision is considered to increase the incidence of this complication.

Methods: A prospective randomized study was conducted after including ninety-nine bikini and ninety-six longitudinal incision DAA cases from May to November 2020. Read More

View Article and Full-Text PDF

Incorporation of a mock pharmacy and therapeutics committee as an entrustable professional activity supporting task.

Curr Pharm Teach Learn 2021 Jul 2;13(7):784-788. Epub 2021 Apr 2.

University of Tennessee Health Science Center College of Pharmacy, Department of Clinical Pharmacy and Translational Science, 1924 Alcoa Highway, Box 117, Knoxville, TN 37920, United States. Electronic address:

Introduction: Entrustable professional activities (EPAs) denote activities and tasks students should be able to perform by graduation irrespective of their practice setting. Formulary decision-making includes several core EPA related skills, such as utilization of drug information, written, and verbal skills. The objective of this study was to describe an EPA supporting task aimed at improving utilization of evidence-based medicine skills and its impact on student self-perceived confidence, rating of skills needed, and competence. Read More

View Article and Full-Text PDF

High Flow Oxygen Therapy at Two Initial Flow Settings versus Conventional Oxygen Therapy in Cardiac Surgery Patients with Postextubation Hypoxemia: A Single-Center, Unblinded, Randomized, Controlled Trial.

J Clin Med 2021 May 12;10(10). Epub 2021 May 12.

First Department of Intensive Care Medicine, National and Kapodistrian University of Athens Medical School, Evaggelismos General Hospital, 10675 Athens, Greece.

In cardiac surgery patients with pre-extubation PaO/inspired oxygen fraction (FiO) < 200 mmHg, the possible benefits and optimal level of high-flow nasal cannula (HFNC) support are still unclear; therefore, we compared HFNC support with an initial gas flow of 60 or 40 L/min and conventional oxygen therapy. Ninety nine patients were randomly allocated (respective ratio: 1:1:1) to I = intervention group 1 (HFNC initial flow = 60 L/min, FiO = 0.6), intervention group 2 (HFNC initial flow = 40 L/min, FiO = 0. Read More

View Article and Full-Text PDF

Epidemiology of Sports-Related Injuries and Associated Risk Factors in Adolescent Athletes: An Injury Surveillance.

Int J Environ Res Public Health 2021 05 2;18(9). Epub 2021 May 2.

Performance and Sport Rehabilitation Laboratory, Faculty of Sport Sciences, University of Castilla-La Mancha, 45071 Toledo, Spain.

The present study aimed to determine the epidemiology of sport-related injuries in amateur and professional adolescent athletes and the incidence of different risk factors on those injuries. Four hundred ninety-eight athletes aged 14 to 21 voluntarily participated in this prospective injury surveillance, conducted from 1 January 2019 to 31 December 2019. The information collected included: personal data, sports aspects, characteristics of the injuries, and lifestyle. Read More

View Article and Full-Text PDF

Abnormal Body Phenomena in Persons with Major Depressive Disorder.

Psychopathology 2021 Jun 1:1-11. Epub 2021 Jun 1.

Department of Psychological, Health and Territorial Sciences, "G. d'Annunzio" University, Chieti, Italy.

Background: Depressive disorders, despite being classified as mood or affective disorders, are known to include disturbances in the experience of body, space, time, and intersubjectivity. However, current diagnostic manuals largely ignore these aspects of depressive experience. In this article, we use phenomenological accounts of embodiment as a theoretical foundation for a qualitative study of abnormal body phenomena (ABP) in depressive disorders. Read More

View Article and Full-Text PDF

MALDI mass spectrometry imaging unravels organ and amyloid-type specific peptide signatures in pulmonary and gastrointestinal amyloidosis.

Proteomics Clin Appl 2021 Jun 1:e2000079. Epub 2021 Jun 1.

Department of Pathology, Christian-Albrechts-University, Kiel, Germany.

Purpose: Amyloidosis is a disease group caused by pathological aggregation and deposition of peptides in diverse tissue sites. Recently, matrix-assisted laser desorption/ionization mass spectrometry imaging coupled with ion mobility separation (MALDI-IMS MSI) was introduced as a novel tool to identify and classify amyloidosis using single sections from formalin-fixed and paraffin-embedded cardiac biopsies. Here, we tested the hypothesis that MALDI-IMS MSI can be applied to lung and gastrointestinal specimens. Read More

View Article and Full-Text PDF