131 results match your criteria rate single-needle

A MEMS Based Drug Delivery Device with Integrated Micro-Needle Array - Design and Simulation.

J Biomech Eng 2021 Apr 5. Epub 2021 Apr 5.

Department of Mechanical and Manufacturing Engineering, Ontario Tech University, Oshawa, Ontario, Canada.

One of the most effective treatments for type 1 and 2 diabetes is the administration of Insulin. Single needle mechanical insulin pumps are heavy and painful. Micro-needle based MEMS drug delivery devices can be an excellent solution for insulin dosing. Read More

View Article and Full-Text PDF

Synthesis and Characterization of Exopolysaccharide Encapsulated PCL/Gelatin Skin Substitute for Full-Thickness Wound Regeneration.

Polymers (Basel) 2021 Mar 10;13(6). Epub 2021 Mar 10.

Université Clermont Auvergne, CNRS, Clermont Auvergne INP, Institut Pascal, F-63000 Clermont-Ferrand, France.

Loss of skin integrity can lead to serious problems and even death. In this study, for the first time, the effect of exopolysaccharide (EPS) produced by cold-adapted yeast sp. GUMS16 on a full-thickness wound in rats was evaluated. Read More

View Article and Full-Text PDF

[Modified single-needle arthroscopic repair technique for the treatment of longitudinal meniscal tear].

Zhongguo Gu Shang 2021 Feb;34(2):114-20

Department of Orthopaedics, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.

Objective: To compare therapeutic efficacy of modified single-needle arthroscopic repair technique and Fast-Fix technique in repairing longitudinal meniscus injuries.

Methods: From July 2016 to July 2017, patients with longitudinal meniscus injuries who underwent meniscal repair surgery were retrospectively analyzed. Ninety-one patients treated with modified single-needle technique and 77 patients were treated with Fast-Fix technique, the average age were (26. Read More

View Article and Full-Text PDF
February 2021

Comparison of contrast-enhanced ultrasound versus conventional ultrasound-guided percutaneous nephrolithotomy in patients with nondilated collecting system: a randomized controlled trial.

Eur Radiol 2021 Feb 26. Epub 2021 Feb 26.

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Objective: To compare the safety, effectiveness, and feasibility of contrast-enhanced ultrasound (CEUS) versus conventional ultrasound-guided percutaneous nephrolithotomy (PCNL) in patients with nondilated collecting system.

Methods: Between July 2018 and July 2020, 160 kidney stone patients with nondilated collecting system planned for PCNL were randomly assigned into two groups, CEUS with retrograde ureteral contrast injection and conventional ultrasound with retrograde ureteral normal saline injection. Patient's demographics, the success rate of puncture, success rate of a single-needle puncture, number of punctures, puncture time, perioperative outcomes, stone-free rate, and incidence of complications were compared. Read More

View Article and Full-Text PDF
February 2021

Single-insertion technique for anesthetizing the inferior alveolar nerve, lingual nerve, and long buccal nerve for extraction of mandibular first and second molars: a prospective study.

J Korean Assoc Oral Maxillofac Surg 2020 Dec;46(6):403-408

Department of Oral and Maxillofacial Surgery, Kunhitharuvai Memorial Charitable Trust (KMCT) Dental College, Calicut, India.

Objectives: Appropriate and accurate local anesthetic (LA) techniques are indispensable in the field of oral and maxillofacial surgery to obtain a satisfactory outcome for both the operating surgeon and the patient. When used alone, the inferior alveolar nerve block (IANB) technique requires supplemental injections like long buccal nerve block for extraction of mandibular molars leading to multiple traumatic experiences for the patient. The aim of this study was to anesthetize the inferior alveolar, lingual, and long buccal nerves with single-needle penetration requiring a minimal skillset such as administering a conventional IANB through introduction of the Benny Joseph technique for extraction of mandibular molars. Read More

View Article and Full-Text PDF
December 2020

Boosting total oxidation of propane over CeO@CoO nanofiber catalysts prepared by multifluidic coaxial electrospinning with continuous grain boundary and fast lattice oxygen mobility.

J Hazard Mater 2021 Mar 2;406:124695. Epub 2020 Dec 2.

Digital Fujian Internet-of-Things Laboratory of Environmental Monitoring, Fujian Normal University, Fuzhou 350007, China; Fuqing Branch of Fujian Normal University, Fuqing 350300, China. Electronic address:

A one-dimensional (1D) core-shell of Co-Ce oxide has been prepared by multifluidic coaxial electrospinning method and evaluated for the total oxidation of propane (CH). Activity and morphological characterizations show that the CeO@CoO nanofiber catalyst, of which the core is CeO and the shell is CoO, exhibits excellent oxidation activity. The exposed CoO grown on the outside of the fibers can rapidly react with CH while CeO with high oxygen storage capacity in the inside is conductive to the enhanced oxidation rate. Read More

View Article and Full-Text PDF

Double-Needle Lavage for Effective Treatment of Difficult-Aspiration Thyroid Cystic Nodules: A Single-Center Controlled Trial.

J Vasc Interv Radiol 2020 10 15;31(10):1675-1681. Epub 2020 Sep 15.

Department of Tumor Interventional Oncology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, 160# Pujian Road, Shanghai, 200127, China. Electronic address:

Purpose: To explore the safety and efficacy of double-needle lavage (DNL) in the treatment of difficult aspiration thyroid cystic nodules.

Materials And Methods: This single-center, prospective, randomized controlled trial was conducted using 100 thyroid cysts from 100 patients who were treated in our hospital from January 2018 to August 2019. These patients were placed into 2 groups; group A including 40 patients treated with single-needle aspiration (SNA), and group B including 60 patients treated with DNL. Read More

View Article and Full-Text PDF
October 2020

[Surgical strategy selection and experience summary of prostate cancer with positive single needle biopsy].

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Aug;52(4):625-631

Objective: To analyze the clinicopathological characteristics of prostate cancer patients undertaking radical prostatectomy with single positive core biopsy, and to optimize the rational choice of therapeutic strategy.

Methods: In the study, 53 patients with single positive core prostate biopsy and treated by radical prostatectomy from January 2010 to December 2018, were analyzed retrospectively. The mean age was (69. Read More

View Article and Full-Text PDF

Automatic multi-needle localization in ultrasound images using large margin mask RCNN for ultrasound-guided prostate brachytherapy.

Phys Med Biol 2020 10 9;65(20):205003. Epub 2020 Oct 9.

Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, GA, United States of America.

Multi-needle localization in ultrasound (US) images is a crucial step of treatment planning for US-guided prostate brachytherapy. However, current computer-aided technologies are mostly focused on single-needle digitization, while manual digitization is labor intensive and time consuming. In this paper, we proposed a deep learning-based workflow for fast automatic multi-needle digitization, including needle shaft detection and needle tip detection. Read More

View Article and Full-Text PDF
October 2020

Central venous catheterization in cancer patients with severe thrombocytopenia: Ultrasound-guide improves safety avoiding prophylactic platelet transfusion.

Mol Clin Oncol 2020 May 5;12(5):435-439. Epub 2020 Mar 5.

Department of Onco-Haematology, Hospital Guglielmo da Saliceto, I-29121 Piacenza, Italy.

Prior research has revealed that ultrasound (US) guided central venous catheterization (CVC) is associated with a reduction in the complication rate such as pneumothorax and an improved first-pass success placing CVC in the internal jugular vein. The present study investigated if US-guided CVC, in a subset of cancer patients with severe thrombocytopenia, reduced bleeding risk and avoided prophylactic platelet transfusion. The efficacy and safety of US-guided CVC placement in cancer patients with severe thrombocytopenia was retrospectively analyzed over a period of 9 years (Dec 2000-Jan 2009), 1,660 and 207 patients with cancer underwent US-guided CVC placement into internal jugular vein respectively at the Department of Onco-Haematology, Hospital of Piacenza. Read More

View Article and Full-Text PDF

[Shear wave elastography for guiding prostate puncture and differential diagnosis of prostatic lesions].

Zhonghua Nan Ke Xue 2019 Sep;25(9):792-796

Department of Urology, Hefei Second People's Hospital, Hefei, Anhui 230011, China.

Objective: To assess the value of transrectal shear wave elastography (SWE) in improving the detection of PCa and differentiating benign from malignant prostatic lesion.

Methods: We performed transrectal ultrasonography (TRUS) and SWE for 83 PCa-suspected patients and measured the maximum (Emax) and mean elastic modulus (Emean) of the lesions. In addition to conventional "6+X" puncture, we conducted SWE-guided prostate puncture and evaluated SWE in improving the detection rate of PCa based on the pathological results. Read More

View Article and Full-Text PDF
September 2019

Percutaneous drainage of retroperitoneal abscesses: variables for success, failure, and recurrence.

Diagn Interv Radiol 2020 Mar;26(2):124-130

Department of Radiology, Hacettepe University School of Medicine, Ankara, Turkey.

Purpose: We aimed to evaluate the success and failure rates and minor and major complications of percutaneous drainage of retroperitoneal abscesses.

Methods: Between 1990 and 2010, percutaneously drained 170 retroperitoneal abscesses in 150 patients (83 males, 67 females, median age 44.2 years, age range, 1-86 years) were included retrospectively. Read More

View Article and Full-Text PDF

Single Needle Granulocyte and Monocyte Apheresis for Ulcerative Colitis: A Retrospective Safety Analysis.

Kurume Med J 2020 Jul 15;66(1):1-7. Epub 2020 Jan 15.

Kurume University Hospital Advanced Emergency Medical Service Center.

Introduction: Granulocyte and monocyte apheresis (GMA) is an effective treatment strategy for active ulcerative colitis (UC) in Japan. Single needle (SN) apheresis reduces needle puncture pain in patients because it requires only one puncture site. We evaluated whether single-needle apheresis could be a safe and effective means of reducing patient burden. Read More

View Article and Full-Text PDF

Selective Sebaceous Gland Electrothermolysis Using a Single Microneedle Radiofrequency Device for Acne Patients: A Prospective Randomized Controlled Study.

Lasers Surg Med 2020 06 10;52(5):396-401. Epub 2019 Sep 10.

Department of Dermatology, Chung-Ang University College of Medicine, Seoul, Korea.

Background And Objectives: The selective electrothermolysis of the sebaceous glands was suggested as a novel therapeutic option for facial acne. However, there has been no randomized controlled trial to evaluate the effectiveness and safety of the monopolar radiofrequency (RF) device using single microneedle with proximal insulation. The objective of the study was to evaluate the efficacy and tolerability of intralesional electrothermolysis using monopolar RF device and proximally-insulated single microneedle in acne patients. Read More

View Article and Full-Text PDF

Single or double needle insertion in twin's amniocentesis: Does the technique influence the risk of complications?

Eur J Obstet Gynecol Reprod Biol X 2019 Jul 15;3:100051. Epub 2019 May 15.

Helen Schneider Hospital for Women, Rabin Medical Center - Beilinson Hospital, Petach Tikva, Israel.

Objective: To compare complication rates following amniocentesis in twin gestations, according to sampling technique and number of needle insertions.

Study Design: A retrospective cohort study of all women with twin gestations who underwent amniocentesis and delivered in a single university affiliated medical center during 2002-2016. Amniocentesis was performed either through one uterine entry with passage through the inter-twin membrane or through two different entries to the two amniotic sacs. Read More

View Article and Full-Text PDF

Scaled-Up Production and Tableting of Grindable Electrospun Fibers Containing a Protein-Type Drug.

Pharmaceutics 2019 Jul 11;11(7). Epub 2019 Jul 11.

Department of Organic Chemistry and Technology, Budapest University of Technology and Economics (BME), Műegyetem rakpart 3, H-1111 Budapest, Hungary.

The aims of this work were to develop a processable, electrospun formulation of a model biopharmaceutical drug, β-galactosidase, and to demonstrate that higher production rates of biopharmaceutical-containing fibers can be achieved by using high-speed electrospinning compared to traditional electrospinning techniques. An aqueous solution of 7.6 /% polyvinyl alcohol, 0. Read More

View Article and Full-Text PDF

[Single needle versus double needle celiac trunk neurolysis in abdominal malignancy pain management: a randomized controlled trial].

Rev Bras Anestesiol 2019 May - Jun;69(3):284-290. Epub 2019 May 10.

Mansoura University, Faculty of Medicine, Department of Radiology, Mansoura, Egito.

Background: Computerized tomography-guided celiac plexus neurolysis has become almost a safe technique to alleviate abdominal malignancy pain. We compared the single needle technique with changing patients' position and the double needle technique using posterior anterocrural approach.

Methods: In Double Needles Celiac Neurolysis Group (n = 17), we used two needles posterior anterocrural technique injecting 12. Read More

View Article and Full-Text PDF
January 2020

Comparison of cytological adequacy and pain scale score in ultrasound-guided fine-needle aspiration of solid thyroid nodules for liquid-based cytology with with 23- and 25-gauge needles: a single-center prospective study.

Sci Rep 2019 05 7;9(1):7027. Epub 2019 May 7.

Department of Radiology, Gyeongsang National University Changwon Hospital, Gyeongsang National University School of Medicine, Changwon, 51476, South Korea.

In ultrasound (US)-guided fine-needle aspiration (FNA) of solid thyroid nodules (STN) using liquid-based cytology (LBC), the most appropriate needle size for LBC remains unclear. This study compared the cytological adequacy and complications associated with using 23- and 25-gauge needles in US-guided FNA of STNs using LBC. US-guided FNA was performed in consecutive patients by one radiologist to diagnose STNs ≥ 5 mm in the largest diameter. Read More

View Article and Full-Text PDF

A survey of current clinical practice of chorionic villus sampling.

Prenat Diagn 2019 03 20;39(4):299-302. Epub 2019 Feb 20.

Fetal Medicine Unit, Department of Obstetrics and Gynaecology, St George's University Hospitals NHS Foundation Trust, London, UK.

Objective: The number of invasive procedures (chorionic villus sampling (CVS) or amniocentesis) for fetal testing is decreasing because of the availability of non-invasive prenatal test (NIPT) leading to a centralisation of prenatal diagnostic services to accredited fetal medicine centres. A new survey was conducted 10 years after the previous one to update the current clinical practice among clinicians who regularly perform CVS.

Method: Consultants from 32 centres in the United Kingdom were invited to take part in an online survey evaluating: The total number of CVS procedures carried out in the unit in a typical week, the preferred route (transabdominal [TA] vs transcervical [TC]), technique (use of local anaesthetic [LA] and needle technique). Read More

View Article and Full-Text PDF

Turkish Insulin Injection Technique Study: Population Characteristics of Turkish Patients with Diabetes Who Inject Insulin and Details of Their Injection Practices as Assessed by Survey Questionnaire.

Diabetes Ther 2018 Aug 30;9(4):1629-1645. Epub 2018 Jun 30.

BD Diabetes Care, POB 13, Erembodegem-Dorp 86, 9320, Erembodegem, Belgium.

Introduction: Over 7 million people in Turkey have diabetes. Of the 1 million who inject insulin little is known of their habits and injection techniques.

Methods: We conducted an Injection Technique Questionnaire (ITQ) survey throughout Turkey that involved 1376 patients from 56 centers. Read More

View Article and Full-Text PDF

Effectiveness of a New Single-Needle Single-Pump Dialysis System with Simultaneous Monitoring of Dialysis Dose.

Artif Organs 2018 Aug 16;42(8):814-823. Epub 2018 Apr 16.

Department of Medical Scientific Affairs, B. Braun Avitum AG, Melsungen, Germany.

To date, single-needle (SN) hemodialysis (HD) requires a dialysis machine equipped with two blood pumps-one controlling arterial blood flow (Qb) and one controlling venous Qb. B. Braun has developed an innovative single-pump SN HD system. Read More

View Article and Full-Text PDF

A comparative study of single-needle and coaxial electrospun amyloid-like protein nanofibers to investigate hydrophilic drug release behavior.

Int J Biol Macromol 2018 Jul 3;114:989-997. Epub 2018 Apr 3.

Plasma Aided Biomedical Research Group (pabmed), Biomedical Engineering Division, Graduate School of Science and Technology, TOBB University of Economics and Technology, Ankara 06560, Turkey; Plasma Aided Biomedical Research Group (pabmed), Biomedical Engineering Department, Engineering Faculty, TOBB University of Economics and Technology, Ankara 06560, Turkey. Electronic address:

In this study, nanofibers containing an amyloid-like bovine serum albumin (AL-BSA) carrier and a model drug (ampicillin) were produced by electrospinning. The release behavior of ampicillin was compared from electrospun nanofibers prepared as either coaxial or single-needle types. SEM images showed that the membranes had a uniform and smooth structure and the core/shell fibers were found to be thicker than the core fibers. Read More

View Article and Full-Text PDF

Minimally Invasive Electrochemotherapy Procedure for Treating Nasal Duct Tumors in Dogs using a Single Needle Electrode.

Radiol Oncol 2017 Dec 1;51(4):422-430. Epub 2017 Nov 1.

Universidad de Buenos Aires, Facultad de Ciencias Exactas y Naturales, Departamento de Física, Buenos Aires, Argentina.

Background: Nasal cavity tumors are usually diagnosed late, when they already have infiltrated adjacent tissues thus requiring very aggressive treatments with serious side effects. Here we use electrochemotherapy (ECT), a well demonstrated treatment modality for superficial tumors.

Materials And Methods: In the case of deep-seated tumors, the main limitation of ECT is reaching the tumor with an appropriate electric field. Read More

View Article and Full-Text PDF
December 2017

Total Outflow Facility in Live C57BL/6 Mice of Different Age.

Biomed Hub 2017 Sep-Dec;2(3):1-10. Epub 2017 Nov 17.

Doheny Eye Institute and Department of Ophthalmology, University of California, Los Angeles, Los Angeles, CA, USA.

Purpose: To characterize total outflow facility across the live adult mouse lifespan as a reference for mouse glaucoma studies and the common C57BL/6 background strain.

Methods: Microperfusion was performed by single-needle cannulation and feedback-controlled coupling of pressure and flow to maintain a constant pressure in the anterior chambers of live C57BL/6NCrl mice aged 3-4 months ( = 17), 6-9 months ( = 10), and 23-27 months ( = 12). This mouse age range represented an equivalent human age range of young adult to elderly. Read More

View Article and Full-Text PDF
November 2017

CT-guided radiofrequency ablation of osteoid osteoma using a multi-tined expandable electrode system.

Acta Biomed 2017 10 18;88(4S):31-37. Epub 2017 Oct 18.


Background And Aim Of The Work: Radiofrequency ablation (RFA) is the gold standard for the treatment of symptomatic osteoid osteoma (OO) as RFA yields both a high success and low complication rate. It has been widely utilized over the years, but recurrences of OO after this treatment have been documented. These recurrences may be the result of various factors, including incomplete tumor ablation, and are significantly higher in lesions greater than 10 mm. Read More

View Article and Full-Text PDF
October 2017

A Phase-Separation Route to Synthesize Porous CNTs with Excellent Stability for Na Storage.

Small 2017 06 20;13(22). Epub 2017 Mar 20.

Department of Materials Science & Engineering, University of Washington, Seattle, WA, 98195, USA.

Porous carbon nanotubes (CNTs) are obtained by removing MoO nanoparticles from MoO @C core@shell nanofibers which are synthesized by phase-segregation via a single-needle electrospinning method. The specific surface area of porous CNTs is 502.9 m g , and many oxygen-containing functional groups (COH, CO) are present. Read More

View Article and Full-Text PDF

A novel adaptive needle insertion sequencing for robotic, single needle MR-guided high-dose-rate prostate brachytherapy.

Phys Med Biol 2017 05 13;62(10):4031-4045. Epub 2017 Mar 13.

Department of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, Netherlands.

MR-guided high-dose-rate (HDR) brachytherapy has gained increasing interest as a treatment for patients with localized prostate cancer because of the superior value of MRI for tumor and surrounding tissues localization. To enable needle insertion into the prostate with the patient in the MR bore, a single needle MR-compatible robotic system involving needle-by-needle dose delivery has been developed at our institution. Throughout the intervention, dose delivery may be impaired by: (1) sub-optimal needle positioning caused by e. Read More

View Article and Full-Text PDF

Dynamic Evaluation of Lavage Efficacy in Upper Compartment of the Temporomandibular Joint.

J Oral Maxillofac Surg 2017 Feb 30;75(2):276-283. Epub 2016 Aug 30.

Professor, Department of Orthodontics, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-Sen University, Guangzhou; Guangdong Provincial Key Laboratory of Stomatology, Guangzhou, China. Electronic address:

Purpose: The aim of this study was to determine the most efficient temporomandibular joint (TMJ) lavage technique for complete irrigation and removal of synovial fluid. The corresponding total lavage fluid volume needed also was investigated.

Materials And Methods: Three-dimensional TMJ lavage models of the classic double- and single-needle techniques with modified cannula sizes (diameters, 2. Read More

View Article and Full-Text PDF
February 2017

Modeling of Drug Delivery by A Pump Driven Micro-Needle Array System.

Open Biomed Eng J 2016 30;10:19-33. Epub 2016 Mar 30.

Department of Mechanical Engineering, University of Texas, San Antonio, USA.

Background: Micro-needles were proposed as one of the alternatives to deliver drugs painlessly passing through stratum corneum in recent years. In this work, a mathematical model is presented to characterize the in fusion flow of a hollow micro-needle array driven by a micro-pump.

Methods: By assuming the injection of each micro-needle undergoes a spherical expansion and diffusion, the model is able to calculate the time-varying expansion radius, and the diffusion boundary, provided that the material properties and the micro-needle system parameters are known. Read More

View Article and Full-Text PDF