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Impact of EfOM in the elimination of PPCPs by UV/chlorine: Radical chemistry and toxicity bioassays.

Water Res 2021 Sep 7;204:117634. Epub 2021 Sep 7.

Institut de Chimie des Milieux et des Matériaux IC2MP UMR 7285 CNRS, Université de Poitiers, France. Electronic address:

The UV/chlorine process as a potential tertiary municipal wastewater treatment alternative for removing refractory PPCPs has been widely investigated. However, the role of effluent organic matter (EfOM) on the radical chemistry and toxicity alteration is unclear. The elimination of two model PPCPs, primidone (PRM) and caffeine (CAF), by the co-exposure of UV and free chlorine was investigated to elucidate the impact of EfOM. Read More

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September 2021

Optimization of constant-current operation in membrane capacitive deionization (MCDI) using variable discharging operations.

Water Res 2021 Sep 9;204:117646. Epub 2021 Sep 9.

UNSW Centre for Transformational Environmental Technologies, Yixing, Jiangsu 214206, PR China; School of Civil and Environmental Engineering, University of New South Wales, Sydney, NSW 2052, Australia. Electronic address:

Membrane capacitive deionization (MCDI) is an emerging electric field-driven technology for brackish water desalination involving the removal of charged ions from saline source waters. While the desalination performance of MCDI under different operational modes has been widely investigated, most studies have concentrated on different charging conditions without considering discharging conditions. In this study, we investigate the effects of different discharging conditions on the desalination performance of MCDI electrode. Read More

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September 2021

Dual cathode configuration and headspace gas recirculation for enhancing microbial electrosynthesis using Sporomusa ovata.

Chemosphere 2021 Sep 7;287(Pt 3):132188. Epub 2021 Sep 7.

Biochemical Process Engineering, Division of Chemical Engineering, Department of Civil, Environmental and Natural Resources Engineering, Luleå University of Technology, 971-87, Luleå, Sweden.

High-rate production of acetate and other value-added products from the reduction of CO in microbial electrosynthesis (MES) using acetogens can be achieved with high reducing power where H appears as a key electron mediator. H evolution using metal cathodes can enhance the availability of H to support high-rate microbial reduction of CO. Due to the low solubility of H, the availability of H remains limited to the bacteria. Read More

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September 2021

The feasibility of medical unmanned aerial systems in suburban areas.

Am J Emerg Med 2021 Aug 31;50:532-545. Epub 2021 Aug 31.

University of Virginia, USA. Electronic address:

Out-of-Hospital Cardiac Arrests (OHCA) are one of the biggest challenges facing medical systems world-wide. Each year, more than 420,000 Americans experience cardiac arrests with a survival rate of approximately 10%. A large challenge to treating OHCA continues to be rapid access to AEDs which can increase survival rates up to 40%. Read More

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Multimedia fate model and risk assessment of typical antibiotics in the integrated demonstration zone of the Yangtze River Delta, China.

Sci Total Environ 2021 Sep 14;805:150258. Epub 2021 Sep 14.

Department of Civil, Architectural and Environmental Engineering, The University of Texas at Austin, Austin, TX, 78712,USA.

Due to the widespread consumption of antibiotics by humans and animals, antibiotic residues from human and animal excrements are released into the environment through domestic sewage and breeding wastewater, which ultimately affect the ecological environment and human health. In this study, the concentrations of 10 antibiotics in the air, water, soil, and sediment from 2013 to 2019 in Qingpu District of the integrated demonstration zone of the Yangtze River Delta were predicated by developing a dynamic Level IV fugacity model. The influence of seasonal environmental factors (e. Read More

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September 2021

Cardiothoracic Surgery Training Program Director Awareness of Available Visiting Medical Student Clerkships for the Underrepresented in Medicine.

Semin Thorac Cardiovasc Surg 2021 Sep 17. Epub 2021 Sep 17.

Division of General Thoracic Surgery, Department of Surgery, University of California, Davis Health, Sacramento, California. Electronic address:

A diversity gap exists within cardiothoracic (CT) surgery that might be addressed with currently available medical student pipeline programs. We sought to assess CT surgery residency/fellowship program directors' (PD) awareness of and participation in underrepresented in medicine visiting medical student clerkship programs (UIM-VMSCPs). We reviewed the ACGME program finder database and medical school websites to identify thoracic surgery training programs that: 1) offer visiting student clerkships (VSCs), 2) are affiliated with an institution offering a UIM-VMSCP, 3) are at an institution where the existing UIM-VMSCP specifically offers rotations in CT surgery. Read More

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September 2021

Outcomes Following the Endovascular Treatment of Renal Artery Stenosis Caused by Fibromuscular Dysplasia: A Systematic Review and Meta-Analysis.

Ann Vasc Surg 2021 Sep 17. Epub 2021 Sep 17.

Department of Vascular Surgery, The 3rd Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong Province, China.

Objective: Renal artery revascularization has been performed to improve blood pressure control and to cure hypertension in patients with renal artery fibromuscular dysplasia (RAFMD). We herein conducted a systematic review and meta-analysis of studies assessing outcomes associated with the treatment of hypertensive RAFMD patients via endovascular angioplasty in order to offer an up-to-date overview of the relative costs and benefits of this approach to revascularization in RAFMD patients.

Methods: We systematically searched the PubMed and Embase databases and the Cochrane Central Register for Controlled Trials to identify relevant studies published as of January 15, 2020. Read More

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September 2021

How to prevent surgical site infection in vascular surgery: A review of the evidence.

Ann Vasc Surg 2021 Sep 17. Epub 2021 Sep 17.

School of Medicine, Faculty of Health and Medical Sciences, The University of Western Australia, Western Australia, Australia. The University of Western Australia, Mailbox Drop Point 509, 35 Stirling Hwy, Nedlands, WA 6009; Department of Vascular and Endovascular Surgery, Sir Charles Gairdner Hospital, Western Australia, Australia. Level 6, G Block, QEII Medical Centre, Hospital Avenue, Nedlands, WA 6009; Curtin Medical School, Curtin University, Western Australia, Australia. Faculty of Health Sciences, Level 4 Building 400, Curtin University, GPO Box U1987, Perth, Western Australia 6845; Heart and Vascular Research Institute, Harry Perkins Institute for Medical Research, Western Australia, Australia. Heart and Vascular Research Institute, Level 2 Harry Perkins Institute of Medical Research, 6 Verdun Street, Nedlands, Western Australia, Australia 6009.

Objective: This review aims to identify and review the current evidence for preventing postoperative surgical site infections in abdominal aortic aneurysm surgery or infrainguinal arterial surgery.

Methods: Extended literature review of clinical trials that examined the prevention of postoperative surgical site infections in abdominal aortic aneurysm or infrainguinal arterial surgery. Searches were conducted on Ovid MEDLINE (1950 - 13 March 2020) using key terms for vascular surgery, surgical site infections and specific preventative techniques. Read More

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September 2021

Migration and Diabetes Incidence Among Chinese Adults in Canada, China, Hong Kong, and Taiwan: An International Population-Based Comparative Study from 2000 to 2017.

Diabetes Res Clin Pract 2021 Sep 17:109062. Epub 2021 Sep 17.

Department of Medicine, University of Toronto, Toronto, Canada; ICES, Toronto, Canada; Department of Medicine, Sunnybrook Health Sciences Centre, Toronto, Canada.

Aims: We conducted an international population-based study comparing the incidence of young- (age 20-39 years) and usual- (age≥40 years) onset diabetes among Chinese-Canadian immigrants; their source populations (mainland China, Hong Kong, Taiwan); and other Canadians.

Methods: Using population-based data (2000-17; n=3.4 million cases), we calculated incidence rates and incidence rate ratios comparing the average incidence for each cohort. Read More

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September 2021

Wide-area transepithelial sampling for dysplasia detection in Barrett's esophagus: a systematic review and meta-analysis.

Gastrointest Endosc 2021 Sep 17. Epub 2021 Sep 17.

Barrett's Esophagus Unit, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota. Electronic address:

Background And Aims: Seattle protocol forceps biopsies (FB) are currently recommended for surveillance in Barrett's esophagus (BE) but limited by sampling error and lack of adherence. Wide-area transepithelial sampling with 3D analysis (WATS-3D) is reported to increase BE dysplasia detection. We assessed the incremental yield and clinical significance of WATS-3D for dysplasia detection over FB in a systematic review and meta-analysis. Read More

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September 2021

Regulation of inflammation and COX-2 gene expression in benzo (a) pyrene induced lung carcinogenesis in mice by all trans retinoic acid (ATRA).

Life Sci 2021 Sep 17:119967. Epub 2021 Sep 17.

Galaxy Health Care, Kolkata 700 156, West Bengal, India.

Aim: Inflammation provides favourable microenvironment for cancer development. An enhanced COX-2 gene expression is a key inflammatory mediator of cancers and the drug that inhibits it, helps to manage cancer effectively and increases survival rate. The objective is to analyse the inflammatory changes and COX-2 gene expression in benzo (a) pyrene induced mice and to evaluate the regulatory effect of all trans retinoic acid. Read More

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September 2021

Use of metoclopramide in the first trimester and risk of major congenital malformations: A systematic review and meta-analysis.

PLoS One 2021 20;16(9):e0257584. Epub 2021 Sep 20.

Department of Pharmacy, Hunan Provincial Maternal and Child Health Care Hospital, Changsha, Hunan, China.

Background: Nausea and vomiting of pregnancy affects up to 80% of pregnant women, it typically occurs during the first trimester which is the most sensitive time for environmental exposures given organogenesis. Metoclopramide is an antiemetic drug used widely during NVP, but the findings of studies evaluating its safety of use in pregnancy is inconsistent. Therefore, we conducted a systematic review and meta-analysis to assess whether metoclopramide use during first trimester of pregnancy is associated with the risk of major congenital malformations. Read More

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September 2021

Towards identifying optimal biased feedback for various user states and traits in motor imagery BCI.

IEEE Trans Biomed Eng 2021 Sep 20;PP. Epub 2021 Sep 20.

Objective: Neural self-regulation is necessary for achieving control over brain-computer interfaces (BCIs). This can be an arduous learning process esspecially for motor imagery BCI. Various training methods were proposed to assist users in accomplishing BCI control and increase performance. Read More

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September 2021

Case 294: Catastrophic Antiphospholipid Syndrome.

Radiology 2021 Oct;301(1):242-246

From the Departments of Radiology (M.G., M.B., M.P.R.) and Internal Medicine (N.C.C.), Cochin Hospital, APHP.Centre, 27 Rue du Fg St Jacques, Paris 75014, France; and Université de Paris, Paris, France (M.B., N.C.C., M.P.R.).

History A 50-year-old woman presented to the emergency department of our hospital with a 2-day history of lower limb pain associated with unusual asthenia and diffuse arthralgia over the past 3 weeks. She was a native of Guinea and had lived in France for most of her life, working as a personal care assistant. Her only medical history of note was an occurrence of fetal death at 12 weeks gestation when she was 35 years old. Read More

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October 2021

Identification and Screening of Potential Bioactive Peptides with Sleep-Enhancing Effects in Bovine Milk Casein Hydrolysate.

J Agric Food Chem 2021 Sep 20. Epub 2021 Sep 20.

School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China.

Casein tryptic hydrolysate (CTH) has been proven to possess stress-relieving and sleep-enhancing effects, but only one decapeptide YLGYLEQLLR (α-CZP) in CTH was reported to exhibit affinity for the benzodiazepine site of a GABA receptor (GABAR). This study aimed to compare the sleep-enhancing effects between CTH and α-CZP and to explore novel sleep-enhancing peptides. Our results showed that CTH significantly prolonged sleep duration in mice, which was almost 2-fold longer than that of α-CZP. Read More

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September 2021

Application of lipidomics strategy to explore aging-related biomarkers and potential anti-aging mechanisms of ginseng.

Biogerontology 2021 Sep 20. Epub 2021 Sep 20.

State Key Laboratory of Component Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, No.10, Poyang Lake Road, Tuanbo New City, Jinghai District, Tianjin, 301617, China.

Aging often leads to an increase risk of age-related diseases, and the development of anti-aging drugs have become the trend and focus of the current scientific research. In this experiment, serum samples from healthy people of different ages were analyzed based on clinical lipidomics, and a total of 10 potential biomarkers in middle-aged and youth group, 20 biomarkers in the youth and the elderly group were obtained. Furthermore, dhSph and dhCer involved above may affect the aging process through sphingolipid metabolic pathway. Read More

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September 2021

Comparison of different treatments for children with radial neck fracture and analysis of prognostic factors.

Arch Orthop Trauma Surg 2021 Sep 20. Epub 2021 Sep 20.

Orthopaedics Department of Shenzhen Children's Hospital, No. 7019, Yitian Road, Futian District, Shenzhen, Guangdong, China.

Introduction: The aim of this was to analyze the effect of different treatment options on radial neck fractures in children and to explore the factors affecting the prognosis of fractures.

Methods: The clinical data of 131 children with radial neck fractures admitted to our hospital from 2010 to 2018 were retrospectively analyzed, and the patients were divided into 6 groups according to treatment methods [manual reduction with Kirschner wires (K-wires) for internal fixation (group A); manual reduction with elastic stable intramedullary nails (ESINs) for internal fixation (group B); leverage reduction with K-wires for internal fixation (group C); leverage reduction with ESINs for internal fixation (group D); manual and leverage reduction with K-wires/ESINs for internal fixation (group E); and open reduction with K-wires/ESINs for internal fixation (group F)]. Postoperative elbow function and complications were analyzed. Read More

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September 2021

Executive functions and their relationship with intellectual capacity and age in schoolchildren with intellectual disability.

J Intellect Disabil Res 2021 Sep 20. Epub 2021 Sep 20.

School of Education and Psychology, Universidad de Navarra, Pamplona, Spain.

Background: There is certain empirical evidence of, on the one hand, a positive correlation between executive functions (EFs) and intelligence in people with intellectual disability (ID) and, on the other hand, a slower rate of development of EFs in these people relative to people without ID. This evidence is not, however, unequivocal, and further studies are required.

Methods: We analysed the relationship between development of EFs and both age and intellectual capacity, in a sample of 106 students with either ID or borderline intellectual functioning (BIF) at a special education centre [63 boys and 43 girls, 11-18 years old, mean total intelligence quotient (TIQ) of 59. Read More

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September 2021

Premorbid Educational Attainment and Long-Term Motor Prognosis in Parkinson's Disease.

J Parkinsons Dis 2021 Sep 16. Epub 2021 Sep 16.

Department of Neurology, Yonsei University College of Medicine, Seoul, South Korea.

Background: Premorbid educational attainment is a well-known proxy of reserve, not only with regard to cognition, but also to motor symptoms.

Objective: In the present study, we investigated the relationship between educational attainment and long-term motor prognosis in patients with Parkinson's disease (PD).

Methods: We analyzed 466 patients with de novo PD without dementia who underwent dopamine transporter (DAT) scans and were followed up more than 2 years. Read More

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September 2021

Endometriosis is associated with an increased whole-blood thrombogenicity detected by a novel automated microchip flow-chamber system (T-TAS®).

Ginekol Pol 2021 Sep 20. Epub 2021 Sep 20.

Division of Reproduction, Poznan University of Medical Sciences, Poland.

Objectives: Potential thrombotic and antifibrinolytic influence of endometriosis on haemostasis has been recently reported in the literature, as well as increased cardiovascular morbidity in women suffering from the disease. We performed a pilot study to assess the influence of endometriosis on the thrombus formation process underin vitroflow conditions.

Material And Methods: This study compared women with confirmed endometriosis (n = 23) surgically and control healthy subjects (n = 10). Read More

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September 2021

Does Fit Mean (f)it? A Comparison of Physiological and Experiential Fitness Data From the iReAct Study.

Front Sports Act Living 2021 1;3:729090. Epub 2021 Sep 1.

Department of Social and Public Health Sciences, Institute of Sport Science, Eberhard Karls University Tübingen, Tübingen, Germany.

Regular exercise fosters fitness-enhancing benefits. We assume that exercise interventions become successful and sustainable if physiological benefits of exercise are also subjectively perceivable. The goal of this study was to examine how young inactive adults to an exercise intervention and how those responses are . Read More

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September 2021

Experimental Technologies in the Diagnosis and Treatment of COVID-19 in Patients with Comorbidities.

J Healthc Inform Res 2021 Sep 15:1-24. Epub 2021 Sep 15.

Carle Illinois College of Medicine, University of Illinois At Urbana-Champaign, Champaign, IL 61820 USA.

The COVID-19 pandemic has impacted the whole world and raised concerns about its effects on different human organ systems. Early detection of COVID-19 may significantly increase the rate of survival; thus, it is critical that the disease is detected early. Emerging technologies have been used to prevent, diagnose, and manage COVID-19 among the populace in the USA and globally. Read More

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September 2021

Sequentially Irradiated and Annealed Highly Cross-Linked Polyethylene: Linear Vector and Volumetric Wear in Total Hip Arthroplasty at 10 Years.

Arthroplast Today 2021 Oct 9;11:140-145. Epub 2021 Sep 9.

Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, Baltimore, MD, USA.

Background: There is a paucity of data on the long-term performance of highly cross-linked polyethylene (HXLPE). Therefore, this study evaluated 10-year 1) functional, 2) radiographic, and 3) surgical outcomes in patients who underwent total hip arthroplasty with sequentially irradiated and annealed HXLPE.

Methods: A retrospective, multicenter study was conducted on patients who underwent primary total hip arthroplasty and received HXLPE polymer (n = 151). Read More

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October 2021

ROCK1 Mediates Retinal Glial Cell Migration Promoted by Acrolein.

Front Med (Lausanne) 2021 3;8:717602. Epub 2021 Sep 3.

Laboratory of Ocular Cell Biology and Visual Science, Department of Ophthalmology, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Acrolein is a highly reactive aldehyde that covalently binds to cellular macromolecules and subsequently modulates cellular function. Our previous study demonstrated that acrolein induces glial cell migration, a pathological hallmark of diabetic retinopathy; however, the detailed cellular mechanism remains unclear. The purpose of this study was to investigate the role of acrolein in retinal glial cell migration by focusing on rho-associated coiled-coil-containing protein kinases (ROCKs). Read More

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September 2021

Predictors of Emergency Room Access and Not Urgent Emergency Room Access by the Frail Older Adults.

Front Public Health 2021 3;9:721634. Epub 2021 Sep 3.

Department of Biomedicine and Prevention, University of Rome "Tor Vergata,"Rome, Italy.

Emergency rooms (ERs) overcrowded by older adults have been the focus of public health policies during the recent COVID-19 outbreak too. This phenomenon needed a change in the nursing care of older frail people. Health policies have tried to mitigate the frequent use of ER by implementing community care to meet the care demands of older adults. Read More

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September 2021

Changes in weight following peroral endoscopic myotomy: results from a North American center.

Endosc Int Open 2021 Oct 16;9(10):E1491-E1496. Epub 2021 Sep 16.

Queen's University, Department of Medicine, Kingston, ON, CAN.

Weight loss is a feature of untreated achalasia. While weight gain after achalasia treatment is expected, little data exist about the extent of it, particularly after peroral endoscopic myotomy (POEM). We aimed to describe the changes in weight after POEM. Read More

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October 2021

Complications With Time-to-Ambulation Following Skin Grafting for Burn Patients: A Meta-Analysis and Systematic Review.

Cureus 2021 Aug 16;13(8):e17214. Epub 2021 Aug 16.

Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, USA.

Accurate models are fundamental tools for risk-stratification, therapy guidance, resource-allocation, and comparative-effectiveness research. Enhanced recovery after surgery (ERAS) protocols increase early post-operative recovery rates in surgical patients. The uniqueness of burn injuries and their post-operative care requires developing a specialized protocol, enhanced recovery after burn surgery (ERABS). Read More

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Major Lower Limb Amputations: Recognizing Pitfalls.

Cureus 2021 Aug 7;13(8):e16972. Epub 2021 Aug 7.

Clinical Surgical Sciences, The University of the West Indies, St. Augustine, TTO.

Major lower extremity amputations have been an area of much concern in the Caribbean population. Hence, the purpose of this research was to investigate the current trends in major lower-extremity amputations. Data regarding all major lower-extremity amputations performed at a tertiary care institution in Trinidad and Tobago, from January 2010 to December 2016 were reviewed. Read More

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Risk factors, bacteriological profile and outcome of surgical site infections following orthopaedic surgery.

Iran J Microbiol 2021 Apr;13(2):171-177

Department of Orthopaedics, Pondicherry Institute of Medical Sciences, Puducherry, India.

Background And Objectives: Surgical site infection (SSI) is a challenge for the surgeon. Incidence of SSI reported in literature varies from 0.5% to 15%. Read More

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Effect of high-quality nursing on negative emotions and hope levels of patients undergoing oral and maxillofacial surgery.

Am J Transl Res 2021 15;13(8):9722-9728. Epub 2021 Aug 15.

Department of Head and Neck Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute Shenyang, Liaoning Province, China.

Objective: To investigate the effect of high-quality nursing on negative emotions and hope levels after oral and maxillofacial surgery (OMS).

Methods: A prospective study involving 120 patients who underwent OMS from December 2018 to January 2020 was conducted. The study subjects were classified into a study group and control group with 60 in each, using a random number table. Read More

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