235,675 results match your criteria rare report


Primary laryngeal T-cell lymphoma: A case report and review of the literature.

Int J Surg Case Rep 2021 Apr 2;82:105858. Epub 2021 Apr 2.

University Hassan II Casablanca, Morocco.

Introduction: Primary lymphoma of the larynx is extremely rare, representing less than 1% of all primary laryngeal neoplasms. It consists mainly of non-Hodgkin lymphomas (NHLs), represented particularly by diffuse large B-cell. Extranodal natural killer/T-cell lymphoma, presented in larynx is a rare condition that accounts for less than 11% of all lymphomas without distinctive clinicopathologic features, as well as challenging pathologic diagnosis. Read More

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A rare case of a laryngeal leiomyosarcoma with a lymph node metastasis.

Int J Surg Case Rep 2021 Mar 23;82:105830. Epub 2021 Mar 23.

ENT and Head and Neck Surgery, Hospital August 20, 1953, Ibn Rochd Teaching Hospital, Casablanca, Morocco. Electronic address:

Introduction: Leiomyosarcoma is a rare mesenchymal tumor that originates from smooth muscle cells. Head and neck LMSs represent only 3% of all leiomyosarcomas with less than 50 cases of laryngeal LMS reported in the literature till now.

Case Presentation: We report a case of 50-year-old male presented at our ENT department for a chronic hoarseness. Read More

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Necrotising fasciitis of the posterior neck crossing the midline: A case report.

Int J Surg Case Rep 2021 Apr 1;82:105851. Epub 2021 Apr 1.

Northwick Park Hospital, London Northwest University Healthcare NHS Trust, Watford Road, Harrow, HA1 3UJ, United Kingdom. Electronic address:

Introduction And Importance: Craniofacial necrotising fasciitis is a complex condition, with high mortality given its propensity to descend via the deep neck spaces into the chest and mediastinum. Management requires optimal antimicrobial therapy with associated aggressive surgical debridement.

Presentation Of Case: A 64-year-old man presented to ENT with a posterior neck swelling. Read More

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Early-onset complete spontaneous migration of contraceptive intrauterine device to the bladder in a post C-section patient: A case report.

Int J Surg Case Rep 2021 Apr 1;82:105850. Epub 2021 Apr 1.

Department of Urology, Faculty of Medicine, Universitas Indonesia, Cipto Mangunkusumo Hospital, Jalan Diponegoro No. 71, Jakarta 10430, Indonesia.

Introduction And Importance: Spontaneous migration of a contraceptive intrauterine device (IUD) to the bladder is very rare. It usually takes years for the IUD to migrate completely from the uterine cavity to the bladder. We report a case of early-onset complete spontaneous migration of contraceptive IUD to the bladder in a post C-section patient. Read More

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True aneurysms of foot arteries: A case report of a young patient.

Ann Vasc Surg 2021 Apr 7. Epub 2021 Apr 7.

The Department of Cardiovascular Surgery, Kagawa Prefectural Central Hospital, Takamatsu, Japan.

Background: Reports of true aneurysms of the lower leg are rare. Among them, cases involving young patients are all the more rare, and there are many unexplored aspects to this pathological condition.

Case Presentation: This is a case of a 30-year-old woman who was referred by an orthopedic surgeon with a chief complaint of severe pain during walking and landing. Read More

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Multiple spontaneous visceral arterial dissections in a patient with Tolosa-Hunt syndrome on corticosteroid therapy.

Ann Vasc Surg 2021 Apr 7. Epub 2021 Apr 7.

Department of Vascular Surgery, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, 310009, China. Electronic address:

Multiple spontaneous visceral arterial dissections are an infrequent occurrence. The etiology, risk factors and natural history of these dissections have not been elucidated, and the optimal therapeutic strategy has not been established. We report a rare case of multiple spontaneous visceral arterial dissections involving the celiac artery, splenic artery, superior mesenteric artery, and right renal artery in a patient with Tolosa-Hunt syndrome on short-term corticosteroid therapy. Read More

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Endovascular treatment of persistent sciatic artery occlusion: case report and literature review.

Ann Vasc Surg 2021 Apr 7. Epub 2021 Apr 7.

Vascular Surgery, Department of Medicine and Surgery, University of Parma, Parma, Italy.

Persistent sciatic artery (PSA) is a rare congenital anatomic variant of the lower limb vascular system with highly variable presentations. The management of lower limb ischemia due to PSA disease is not specifically recommended in guidelines, and surgical by-pass is usually the most described treatment. We reported a case of a 46-year old patient with bilateral PSA and right chronic limb-threatening ischemia due to PSA occlusion at the PSA-popliteal junction which was successfully treated with percutaneous transluminal balloon angioplasty. Read More

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Crystal structure of a novel homodimeric L-ribulose 3-epimerase from Methylomonus sp.

FEBS Open Bio 2021 Apr 10. Epub 2021 Apr 10.

Life Science Research Center, Faculty of Medicine, Kagawa University, 1750-1 Ikenobe, Miki-cho, Kita-gun Kagawa, 761-0793, Japan.

D-allulose has potential as a low calorie sweetener which can suppress fat accumulation. Several enzymes capable of D-allulose production have been isolated, including D-tagatose 3-epimerases. Here, we report the isolation of a novel protein from Methylomonas sp. Read More

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Hypokalemia-Induced Rhabdomyolysis Caused by Adrenal Tumor-Related Primary Aldosteronism: A Report of 2 Cases.

Am J Case Rep 2021 Apr 10;22:e929758. Epub 2021 Apr 10.

Division of Urology, Department of Surgery, Cathay General Hospital, Taipei, Taiwan.

BACKGROUND Primary aldosteronism, also known as Conn's syndrome, is a clinical condition caused by excessive production of aldosterone. The classic presenting signs of primary aldosteronism are hypertension and hypokalemia. However, rhabdomyolysis induced by severe hypokalemia is a rare manifestation of primary aldosteronism. Read More

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Cholecystocolonic fistula as an uncommon cause of diarrhea: a case-report and review of the literature.

Clin J Gastroenterol 2021 Apr 10. Epub 2021 Apr 10.

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA.

Bilio-enteric fistulization is the aberrant connection between the biliary and luminal digestive tracts. The cholecystocolonic fistula (CCF) is the second most common bilio-enteric fistula (comprising 20% of cases), after the cholocystoduodenal fistula (comprising 70% of all cases). A CCF may result from malignancy or more benign etiologies, such as gallstones, and is thought to arise from a chronic inflammatory cadence of tissue necrosis, tissue perforation, and fistula creation. Read More

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Inferior mesenteric arteriovenous fistula with colonic ischemia: a case report and review of the literature.

Clin J Gastroenterol 2021 Apr 10. Epub 2021 Apr 10.

Department of Radiology, Saint-Eloi University Hospital, 80 Av. Augustin Fliche, 34000, Montpellier, France.

Inferior mesenteric arteriovenous fistula is a rare abnormal high flow communication with only 40 primary and secondary cases reported in literature. Shunting of arterial flow through the inferior mesenteric vein to the portal system can cause a variety of nonspecific clinical signs and symptoms usually associated with the diagnosis of arteriovenous malformation. Symptom intensities are flow-dependent and can range from minimal abdominal symptoms to severe heart failure due to left to right shunt. Read More

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The first Japanese family of CDH3-related hypotrichosis with juvenile macular dystrophy.

Mol Genet Genomic Med 2021 Apr 9:e1688. Epub 2021 Apr 9.

Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan.

Background: Hypotrichosis with juvenile macular dystrophy (HJMD) is a rare autosomal recessive inherited disorder caused by biallelic variants in the CDH3 gene encoding P-cadherin. Here, we report two Japanese sibling patients with HJMD.

Methods: Whole-exome sequencing (WES) was performed to identify disease-causing variants. Read More

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Case of photodermatitis caused by Mytilus edulis (blue mussel) presenting with edematous erythema.

Photodermatol Photoimmunol Photomed 2021 Apr 10. Epub 2021 Apr 10.

Department of Dermatology, The second affiliated Hospital of Dalian Medical University, Dalian, 116027, PR China.

Animal-induced photodermatitis is rare, here we report an unusual case of photodermatitis caused by Mytilus edulis to arouse the attention of dermatologists and the education to the public. Clinically, exogenous photosensitizing dermatitis (EPD) includes photocontact dermatitis and actinic drug eruption, and the former can be divided into phototoxic contact dermatitis and photoallergic contact dermatitis. Phytophotodermatitis is a common skin lesion mainly caused by acute phototoxic inflammatory reactions. Read More

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Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice.

Nat Commun 2021 Apr 9;12(1):2121. Epub 2021 Apr 9.

RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.

Prime editors (PEs) mediate genome modification without utilizing double-stranded DNA breaks or exogenous donor DNA as a template. PEs facilitate nucleotide substitutions or local insertions or deletions within the genome based on the template sequence encoded within the prime editing guide RNA (pegRNA). However, the efficacy of prime editing in adult mice has not been established. Read More

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Hodgkin Lymphoma-Associated Superior Vena Cava Syndrome: A Case Report and Review of the Literature.

Am J Case Rep 2021 Apr 10;22:e929437. Epub 2021 Apr 10.

Department of Hematology/Oncology, Saint Agnes Healthcare Cancer Institute, Baltimore, MD, USA.

BACKGROUND Hodgkin lymphoma (HL) is a relatively rare etiology of superior vena cava (SVC) syndrome, with only 24 cases reported in the literature. The characteristics, management, and prognosis of HL-associated SVC syndrome remain unclear. This case report describes nodular sclerosis classical HL and the associated clinical manifestations presenting as SVC syndrome in a middle-aged patient, and it summarizes the characteristics of HL-associated SVC syndrome. Read More

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Rare case of adult-onset phalangeal microgeodic syndrome of the feet.

BMJ Case Rep 2021 Apr 9;14(4). Epub 2021 Apr 9.

Institute of Sport & Exercise Health, London, UK.

Phalangeal microgeodic syndrome (PMS) is a rare condition typically affecting children and is characterised by painful digits precipitated by cold temperatures. In medical literature, cases appear to be clustered in Japan. Adult-onset PMS is particularly rare and although imaging features are characteristic, it may go undiagnosed, as it is not commonly encountered. Read More

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Giant parathyroid adenoma and challenges with preoperative differentiation from malignancy.

BMJ Case Rep 2021 Apr 9;14(4). Epub 2021 Apr 9.

Department of Oral and Maxillofacial Surgery, University Hospitals Sussex NHS Foundation Trust, St Richards Hospital, Chichester and Worthing Hospital, Worthing, UK

Giant parathyroid adenomas are rare and underreported benign tumours of parathyroid gland. Preoperative differentiation between giant parathyroid adenoma (GPA) and parathyroid carcinoma can be challenging, as they both may present as a large parathyroid tumour with hyperparathyroidism. Very few GPAs had been described in the literature, with only 60 cases including our present case. Read More

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Hallux Valgus With Second Brachymetatarsia Discovered Accidentally: A Case Report.

J Foot Ankle Surg 2021 Mar 18. Epub 2021 Mar 18.

Professor, Department of Orthopaedic Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.

Hallux valgus deformity is one of the most common foot and ankle diseases, while brachymetatarsia is a rare foot anomaly with pathological shortening of a metatarsal bone. We present a case of hallux valgus deformity possibly due to second brachymetatarsia. As the hallux valgus was associated with dorsal dislocation of the second toe that made it difficult to evaluate the length of the second toe, the patient was unaware of the second metatarsal shortening until the lengths of the toes compared by manual reposition of the second MTP joint. Read More

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A BERIBERI UNHEALTHY LATTE: ENCEPHALOPATHY AND SHOCK FROM SEVERE NUTRITIONAL DEFICIENCY.

J Emerg Med 2021 Apr 6. Epub 2021 Apr 6.

Department of Emergency Medicine, University of California, San Diego, San Diego, California; Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego, San Diego, California.

Background: Thiamine deficiency is an uncommon cause of severe illness in the United States that can lead to significant morbidity because of high-output cardiac failure, peripheral neuropathy, and permanent neurologic impairment. We report the case of a middle-aged woman with extreme malnutrition caused by complications of Roux-en-Y gastric bypass (RYGB) surgery who presented with signs and symptoms of severe thiamine deficiency and septic shock.

Case Report: A 43-year-old woman who had undergone RYGB surgery and who had multiple complications presented to the emergency department with agitation, confusion, and lethargy. Read More

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Concurrent manifestations of Horner's syndrome and esophageal metastasis of breast cancer: case report of a young woman after a period of non-adherence to treatment: a case report.

J Med Case Rep 2021 Apr 9;15(1):194. Epub 2021 Apr 9.

Division of Surgical Oncology-Department of Surgery, Dr. Sardjito Hospital/Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada, Jl Kesehatan No. 1, Yogyakarta, 55281, Indonesia.

Background: Esophageal involvement and Horner's syndrome are rare manifestations of breast cancer distant metastases that can pose a significant challenge in diagnosis and treatment. In addition to the more aggressive behavior of breast cancer diagnosed in young women, non-adherence to treatment is associated with increased risk of distant metastasis.

Case Presentation: A 36-year-old Javanese woman presented to our institution with dysphagia, hoarseness, and frequent hiccups. Read More

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Parachute mitral valve associated with reticular chordae tendineae in an adult: case report.

J Cardiothorac Surg 2021 Apr 9;16(1):72. Epub 2021 Apr 9.

Department of Cardiovascular Surgery, Second Affiliated Hospital of Zhejiang University, School of Medicine, #88 Jiefang Road, Hangzhou, 310009, China.

Background: Parachute mitral valve with reticular chordae tendineae is an extremely rare anomaly.

Case Presentation: We present a case of parachute mitral valve associated with distinctive reticular chordae tendineae in an adult. It was diagnosed from the echocardiogram. Read More

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Undifferentiated colonic neoplasm with SMARCA4 germline gene mutation and loss of SMARCA4 protein expression: a case report and literature review.

Diagn Pathol 2021 Apr 9;16(1):30. Epub 2021 Apr 9.

Department of Pathology, Xuanwu Hospital, Capital Medical University, 45 Changchun Street, Xicheng District, Beijing, China.

Background: Nonsense mutation or inactivation of SMARCA4 (BRG1) is associated with a monomorphic undifferentiated histological appearance in tumors at different sites. The association between SMARCA4 alteration and undifferentiated colonic carcinoma needs to be further elucidated.

Methods: A 61-year-old male patient presented to the hospital with intermittent epigastric pain in the right upper abdomen and abdominal distension. Read More

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11p11.12p12 duplication in a family with intellectual disability and craniofacial anomalies.

BMC Med Genomics 2021 Apr 9;14(1):99. Epub 2021 Apr 9.

Medical Research Center, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Linhai, Zhejiang, China.

Background: Potocki-Shaffer syndrome (PSS) is a rare contiguous gene deletion syndrome marked by haploinsufficiency of genes in chromosomal region 11p11.2p12. Approximately 50 cases of PSS have been reported; however, a syndrome with a PSS-like clinical phenotype caused by 11p11. Read More

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Uterine pseudoaneurysm on the basis of deep infiltrating endometriosis during pregnancy-a case report.

BMC Pregnancy Childbirth 2021 Apr 9;21(1):282. Epub 2021 Apr 9.

Department of Obstetrics and Gynecology, University Hospital of Basel, Basel, Switzerland.

Background: Pseudoaneurysm of the uterine artery (UPA) is a rare cause of potentially life-threatening hemorrhage during pregnancy and puerperium. It is an uncommon condition that mainly occurs after traumatic injury to a vessel following pelvic surgical intervention, but also has been reported based on underlying endometriosis. There is an increased risk of developing UPA during pregnancy. Read More

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Ataxia telangiectasia mutated germline pathogenic variant in adrenocortical carcinoma.

Cancer Genet 2021 Mar 24;256-257:21-25. Epub 2021 Mar 24.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States; Developmental Therapeutics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, United States. Electronic address:

Background: Adrenocortical carcinoma (ACC) is a rare malignancy arising from the adrenal cortex. ACC carries a dismal prognosis and surgery offers the only chance for a cure. Germline pathogenic variants among certain oncogenes have been implicated in ACC. Read More

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Chordoid glioma: a rare old foe but a new pathological and radiological presentation.

Clin Imaging 2021 Mar 24;78:160-164. Epub 2021 Mar 24.

Department of Radiology, Mayo Clinic, Jacksonville, FL, United States of America. Electronic address:

Chordoid glioma (CG) is a rare WHO Grade II neoplasm of the anterior third ventricle. We report two cases of CG with new presentation in terms of histopathology and location: a case of CG with osseous metaplasia evident on imaging, and another CG, unusually located in the posterior portion of the third ventricle. Read More

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Successful treatment of refractory cystitis associated with systemic lupus erythematosus with Belimumab.

Int Immunopharmacol 2021 Apr 6;96:107574. Epub 2021 Apr 6.

Department of Rheumatology and Immunology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.

Lupus cystitis (LC) is a rare manifestation of SLE, the diagnosis of LC is challenging, especially in the absence of other systemic manifestations or the obvious disease activity index of SLE, further cystoscopy and bladder biopsy are crucial. The symptoms of cystitis could be controlled with high-dose GC, but in the process of GC reduction, the condition repeated. Here we report one case of refractory LC treated with Belimumab. Read More

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Abdominal Aorta Bullet Embolism: Presentation and Management.

Ann Vasc Surg 2021 Apr 6. Epub 2021 Apr 6.

Department of Surgery, Broward Health Medical Center, Fort Lauderdale, FL, 33316.

Penetrating cardiac injury (PCI) secondary to a gunshot wound presents with several complications and a mortality rate of 94% before reaching the hospital. Current literature search reveals that embolism of bullet fragments after gunshot wounds are exceptionally rare. Additionally, no reported case was found regarding bullet embolism following left atrium penetration at the time of this case report. Read More

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A case of Infective Native (Abdominal) Aortic Aneurysm caused by Streptococcus Agalactiae: An updated literature review based on new nomenclature.

Ann Vasc Surg 2021 Apr 6. Epub 2021 Apr 6.

Department of Vascular Surgery, King's College Hospital, Denmark Hill, SE5 9RS, London, United Kingdom. Electronic address:

The management of abdominal aortic aneurysms (AAA) has evolved significantly with the advent of endovascular strategies. Thus, there has been a decline in the number of open AAA repairs once an endovascular option is available. There have also been reports of successful endovascular management of infective native aortic aneurysms (INAA) [1], previously called mycotic aneurysms [2]. Read More

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Open surgical treatment of acute spontaneous isolated abdominal aortic dissection.

Ann Vasc Surg 2021 Apr 6. Epub 2021 Apr 6.

Clinic for Vascular and Endovascular Surgery, Clinical Center of Serbia, Belgrade; Faculty of Medicine, University of Belgrade, Serbia.

Introduction: The aim of this paper is to report our single-center experience in the open surgical treatment of acute spontaneous infrarenal isolated abdominal aortic dissection (siIAAD).

Methods And Patients: This was a single center retrospective study. Between January 2015 and 2020 ten patients were treated due to acute siIAAD with open surgery. Read More

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