40,186 results match your criteria rapid systematic

Refeeding syndrome occurs among older adults regardless of refeeding rates: A systematic review.

Nutr Res 2021 May 21;91:1-12. Epub 2021 May 21.

Department of Nursing and Health Promotion, Faculty of Health Sciences, Oslo Metropolitan University, Oslo 0130, Norway; Regional Advisory Unit for Palliative Care, Department of Oncology, Oslo University Hospital, Oslo 0424, Norway. Electronic address:

Refeeding syndrome is a life-threatening clinical disorder that can occur when treating malnutrition. The aim was to examine the current knowledge of refeeding syndrome in patients ≥ 65 + years with special focus on the incidence of hypophosphatemia (HP) in relation to refeeding rate (kcal/kg/day), number of days until the lowest level of phosphate occurs (day of nadir), refeeding rates and adverse events, and death. Specifically, we hypothesized that higher energy provision would cause a higher incidence of HP. Read More

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Alteration of brain structural connectivity in progression of Parkinson's disease: A connectome-wide network analysis.

Neuroimage Clin 2021 Jun 6;31:102715. Epub 2021 Jun 6.

Department of Neurobiology, Neurology and Geriatrics, Xuanwu Hospital, Capital Medical University, National Clinical Research Center for Geriatric Disease, Beijing, China. Electronic address:

Pinpointing the brain dysconnectivity in idiopathic rapid eye movement sleep behaviour disorder (iRBD) can facilitate preventing the conversion of Parkinson's disease (PD) from prodromal phase. Recent neuroimage investigations reported disruptive brain white matter connectivity in both iRBD and PD, respectively. However, the intrinsic process of the human brain structural network evolving from iRBD to PD still remains largely unknown. Read More

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Raman and quantitative phase imaging allow morpho-molecular recognition of malignancy and stages of B-cell acute lymphoblastic leukemia.

Biosens Bioelectron 2021 Jun 12;190:113403. Epub 2021 Jun 12.

Department of Mechanical Engineering, Johns Hopkins University, Baltimore, MD, 21218, USA; The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA; Department of Oncology, Johns Hopkins University, Baltimore, MD, 21287, USA. Electronic address:

Acute lymphoblastic leukemia (ALL) is one of the most common malignancies that account for nearly one-third of all pediatric cancers. The current diagnostic assays are time-consuming, labor-intensive, and require expensive reagents. Here, we report a label-free approach featuring diffraction phase imaging and Raman microscopy that can retrieve both morphological and molecular attributes for label-free optical phenotyping of individual B cells. Read More

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Non-invasive SERS serum detection technology combined with multivariate statistical algorithm for simultaneous screening of cervical cancer and breast cancer.

Anal Bioanal Chem 2021 Jun 14. Epub 2021 Jun 14.

First Affiliated Hospital of Xinjiang Medical University, Xinjiang, 830046, Urumqi, China.

Surface-enhanced Raman scattering (SERS), as a rapid, reliable and non-destructive spectral detection technology, has made a series of breakthrough achievements in screening and pre-diagnosis of various cancerous tumors. In this paper, high-performance gold nanoparticles/785 porous silicon photonic crystals (Au NPs/785 PSi PhCs) active SERS substrates were specially designed for serum testing, and realized highly sensitive detection of serum from healthy people, patients with cervical cancer and breast cancer. Based on the SERS spectra of the three groups of serum, the significant differences between the healthy group and cancer group at 1030 cm and 1051 cm were analyzed, and the similar but different serum SERS spectra of cervical cancer and breast cancer patients were compared. Read More

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Safety of COVID-19 vaccines, their components or their platforms for pregnant women: A rapid review.

medRxiv 2021 Jun 6. Epub 2021 Jun 6.

Background: Pregnant women with COVID-19 are at an increased risk of severe COVID-19 illness as well as adverse pregnancy and birth outcomes. Many countries are vaccinating or considering vaccinating pregnant women with limited available data about the safety of this strategy. Early identification of safety concerns of COVID-19 vaccines, including their components, or their technological platforms is therefore urgently needed. Read More

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Quantifying Psychopathology in Rapid Readmissions.

CNS Spectr 2021 Apr;26(2):165-166

The Loretto Hospital, Chicago, IL, USA.

Psychiatric readmissions contribute to a significant cost and healthcare burden to physicians, hospitals, and the healthcare system as an entity. Furthermore, as part of the Affordable Care Act, the Centers for Medicare and Medicaid Services (CMS) began to reduce financial coverage to hospitals with overwhelming rehospitalization rates. The purpose of this study was to do a systematic analysis on inpatient psychiatric readmission data and identify co-morbidities and risk factors that lead to high readmission rates. Read More

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Systematic review of cochlear implantation in adults with asymmetrical hearing loss.

Cochlear Implants Int 2021 Jun 14:1-19. Epub 2021 Jun 14.

ENT-H&N Surgery Department, Queen Elizabeth University Hospitals, Birmingham, UK.

Background: Rapid advances in cochlear implantation has witnessed an expanding spectrum for candidacy worldwide. This includes a subgroup of adults with asymmetrical hearing loss who have a wide range in their hearing capacity between the two ears. As per guidelines they are not included in mainstream candidacy for CI across the world. Read More

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Iron-carbon microelectrolysis for wastewater remediation: Preparation, performance and interaction mechanisms.

Chemosphere 2021 Sep 3;278:130483. Epub 2021 Apr 3.

School of Environment, Key Laboratory for Yellow River and Huai River Water Environment and Pollution Control, Ministry of Education, Henan Key Laboratory for Environmental Pollution Control, Henan Normal University, Xinxiang, 453007, China.

Rapid industrialization and urbanization have produced a lot of hazardous substances in water and wastewater, which has turned into a crucial issue to the environment and the public health. Recently, iron carbon microelectrolysis (IC-ME) has attracted extensive attention in environmental remediation due to its low costs and excellent performance. Nevertheless, there is still a lack of a more systematic review on IC-ME preparation methods, their performance, and the interaction mechanisms of IC-ME in the remediation of wastewater. Read More

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September 2021

Yeast Synthetic Minimal Biosensors for Evaluating Protein Production.

ACS Synth Biol 2021 Jun 14. Epub 2021 Jun 14.

ARC Centre of Excellence in Synthetic Biology, Department of Molecular Sciences, Macquarie University, Sydney, NSW 2109, Australia.

The unfolded protein response (UPR) is a highly conserved cellular response in eukaryotic cells to counteract endoplasmic reticulum (ER) stress, typically triggered by unfolded protein accumulation. In addition to its relevance to human diseases like cancer, the induction of the UPR has a significant impact on the recombinant protein production in eukaryotic cell factories, including the industrial workhorse. Being able to accurately detect and measure this ER stress response in single cells, enables the rapid optimization of protein production conditions and high-throughput strain selection strategies. Read More

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Mapping the Evidence on Rapid Diagnosis of Bloodstream Infections: A Scoping Review.

J Appl Lab Med 2021 Jun 14. Epub 2021 Jun 14.

Department of Interdisciplinary Studies, Department of Biostatistics and Epidemiology, School of Health Professions, School of Public Health, Rutgers, The State University of New Jersey, NJ, USA.

Background: Laboratory and other healthcare professionals participate in developing clinical practice guidelines through systematic review of the evidence. A significant challenge is the identification of areas for analytic focus when the evidence consists of several categories of interventions and outcomes that span both laboratory and clinical processes. The challenge increases when these interventions present as sets of combined interventions. Read More

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The pattern of human papillomavirus infection and genotypes among Nigerian women from 1999 to 2019: a systematic review.

Ann Med 2021 Dec;53(1):944-959

WHO National Polio Reference Laboratory, University of Maiduguri Teaching Hospital, Maiduguri, Nigeria.

Background: There are no robust national prevalence of Human Papillomavirus (HPV) genotypes in Nigerian women despite the high burden of cervical cancer morbidity and mortality.

The Objective Of Study: This study aims to determine the pooled prevalence and risk factors of genital HPV infection in Nigeria through a systemic review protocol.

Methods: Databases including PubMed, Scopus, Google Scholar and AJOL were searched between 10 April to 28 July 2020. Read More

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December 2021

Supplementation of Diets With Influences Immune and Gut Function in Dogs.

Front Nutr 2021 28;8:667072. Epub 2021 May 28.

Nestlé Purina Research, One Checkerboard Square, St. Louis, MO, United States.

refers to two species of blue green algae (, and ) consumed by humans as food for centuries. While, has been shown to have immune enhancing properties in several animal and human studies, there are no systematic studies in dogs. The aim of this study was to evaluate the immunomodulatory effect of dietary supplementation with in dogs. Read More

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Expression-EEG Bimodal Fusion Emotion Recognition Method Based on Deep Learning.

Comput Math Methods Med 2021 25;2021:9940148. Epub 2021 May 25.

Department of Electrical & Information Engineering, Sichuan Engineering Technical College, Deyang, Sichuan 618000, China.

As one of the key issues in the field of emotional computing, emotion recognition has rich application scenarios and important research value. However, the single biometric recognition in the actual scene has the problem of low accuracy of emotion recognition classification due to its own limitations. In response to this problem, this paper combines deep neural networks to propose a deep learning-based expression-EEG bimodal fusion emotion recognition method. Read More

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Subcutaneous Ketamine in Depression: A Systematic Review.

Front Psychiatry 2021 28;12:513068. Epub 2021 May 28.

Department and Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil.

Ketamine has been shown to produce a rapid and robust antidepressant effect. Though numerous routes of administration have been studied, subcutaneous (SC) has proven to be a convenient and cost-effective route making its use particularly relevant in developing countries. Here we provide a systematic review covering the use of SC racemic ketamine and esketamine in depression, including its efficacy, safety and tolerability. Read More

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Public Opinion Early Warning Agent Model: A Deep Learning Cascade Virality Prediction Model Based on Multi-Feature Fusion.

Front Neurorobot 2021 28;15:674322. Epub 2021 May 28.

Software Engineering Center, College of Computer, National University of Defense Technology, ChangSha, China.

With the rapid popularity of agent technology, a public opinion early warning agent has attracted wide attention. Furthermore, a deep learning model can make the agent more automatic and efficient. Therefore, for the agency of a public opinion early warning task, the deep learning model is very suitable for completing tasks such as popularity prediction or emergency outbreak. Read More

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Deep Supervised Learning Using Self-Adaptive Auxiliary Loss for COVID-19 Diagnosis from Imbalanced CT Images.

Neurocomputing 2021 Jun 7. Epub 2021 Jun 7.

Key Laboratory of Intelligent Computing and Information Processing of Ministry of Education, Xiangtan University, Xiangtan, 411105, China.

The outbreak and rapid spread of coronavirus disease 2019 (COVID-19) has had a huge impact on the lives and safety of people around the world. Chest CT is considered an effective tool for the diagnosis and follow-up of COVID-19. For faster examination, automatic COVID-19 diagnostic techniques using deep learning on CT images have received increasing attention. Read More

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Mechanistic Study on Thermally Induced Lattice Stiffening of ZIF-8.

Chem Mater 2021 Jun 19;33(11):4035-4044. Epub 2021 May 19.

Laboratory of Advanced Separations (LAS), École Polytechnique Fédérale de Lausanne (EPFL), Rue de l'Industrie 17, CH-1951 Sion, Switzerland.

The flexibility of the ZIF-8 aperture, which inhibits a molecular cutoff of 3.4 Å, can be reduced by rapid heat treatment to obtain CO-selective membranes. However, the early stages of the structural, morphological, and chemical changes responsible for the lattice rigidification remain elusive. Read More

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Co-mutation modules capture the evolution and transmission patterns of SARS-CoV-2.

Brief Bioinform 2021 Jun 14. Epub 2021 Jun 14.

Center for Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100005; Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China.

The rapid spread and huge impact of the COVID-19 pandemic caused by the emerging SARS-CoV-2 have driven large efforts for sequencing and analyzing the viral genomes. Mutation analyses have revealed that the virus keeps mutating and shows a certain degree of genetic diversity, which could result in the alteration of its infectivity and pathogenicity. Therefore, appropriate delineation of SARS-CoV-2 genetic variants enables us to understand its evolution and transmission patterns. Read More

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Acute splanchnic vein thrombosis in patients with COVID-19: A systematic review.

Dig Liver Dis 2021 May 26. Epub 2021 May 26.

Hepatology, Department for Visceral Surgery and Medicine, Bern University Hospital, University of Bern, Switzerland; Hepatology, Department of Biomedical Research, University of Bern, Bern, Switzerland. Electronic address:

There is increasing evidence that coronavirus disease 2019 (COVID-19) is associated with a significant risk of venous thromboembolism. While information are mainly available for deep vein thrombosis of the lower limb and pulmonary embolism, scarce data exist regarding acute splanchnic vein thrombosis (SVT) in this setting. PubMed, EMBASE and Google Scholar English-language articles published up to 30 January 2021 on SVT in COVID-19 were searched. Read More

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Rise and decline of the barbiturate methitural for intravenous anesthesia: A systematic search and narrative synthesis.

Marco Cascella

J Anesth Hist 2021 Mar 30;7(1):11-16. Epub 2020 Dec 30.

Division of Anesthesia and Pain Medicine, Istituto Nazionale Tumori - IRCCS - Fondazione Pascale, Via Semmola, 80100, Napoli, Italy. Electronic address:

Background: Within the history of intravenous anesthesia, barbiturates represent a chapter of considerable importance. Although the reference barbiturate thiopental had several limitations, it dominated the scene of the intravenous anesthesia until the mid-1980s, when propofol was introduced on the market. In the meantime, several barbiturate derivatives were placed on the market and abounded. Read More

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Nothing so practical as theory: a rapid review of the use of behaviour change theory in family planning interventions involving men and boys.

Reprod Health 2021 Jun 13;18(1):126. Epub 2021 Jun 13.

School of Nursing and Midwifery and Centre for Evidence and Social Innovation, Queen's University Belfast, Belfast, Northern Ireland, UK.

Background: There is growing recognition of the need for interventions that effectively involve men and boys to promote family planning behaviours. Evidence suggests that the most effective behavioural interventions in this field are founded on theoretical principles of behaviour change and gender equality. However, there are few evidence syntheses on how theoretical approaches are applied in this context that might guide best practice in intervention development. Read More

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Machine learning classification of origins and varieties of Tetrastigma hemsleyanum using a dual-mode microscopic hyperspectral imager.

Spectrochim Acta A Mol Biomol Spectrosc 2021 Jun 5;261:120054. Epub 2021 Jun 5.

Centre for Optical and Electromagnetic Research, National Engineering Research Center for Optical Instruments, Zhejiang Provincial Key Laboratory for Sensing Technologies, Zhejiang University, Hangzhou 310058, China. Electronic address:

A dual-mode microscopic hyperspectral imager (DMHI) combined with a machine learning algorithm for the purpose of classifying origins and varieties of Tetrastigma hemsleyanum (T. hemsleyanum) was developed. By switching the illumination source, the DMHI can operate in reflection imaging and fluorescence detection modes. Read More

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Progress towards a cellularly resolved mouse mesoconnectome is empowered by data fusion and new neuroanatomy techniques.

Neurosci Biobehav Rev 2021 Jun 10. Epub 2021 Jun 10.

Neuroinformatics department, Donders Centre for Neuroscience, Radboud University Nijmegen, Heyendaalseweg 135, 6525 AJ Nijmegen, the Netherlands.

Over the past decade there has been a rapid improvement in techniques for obtaining large-scale cellular level data related to the mouse brain connectome. However, a detailed mapping of cell-type-specific projection patterns is lacking, which would, for instance, allow us to study the role of circuit motifs in cognitive processes. In this work, we review advanced neuroanatomical and data fusion techniques within the context of a proposed Multimodal Connectomic Integration Framework for augmenting the cellularly resolved mouse mesoconnectome. Read More

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Analysis of the curative effect and influencing factors of stereotactic aspiration in the treatment of primary brainstem haemorrhage.

J Clin Neurosci 2021 Jul 10;89:122-127. Epub 2021 May 10.

Department of Neurosurgery, The First Hospital of Hebei Medical University, Shijiazhuang, China. Electronic address:

Primary brainstem haemorrhage (PBH) is characterized by acute onset, rapid deterioration, many complications, and poor prognosis. Its treatment has been controversial. This study aimed to explore the clinical risk factors of postoperative survival and neurological function recovery of stereotactic aspiration in the treatment of PBH. Read More

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A berberrubine-derived fluorescent probe for hydrazine and its practical application in water and food samples.

Anal Chim Acta 2021 Aug 11;1172:338504. Epub 2021 Apr 11.

College of Chemical Engineering, Nanjing Forestry University, 159 Longpan Road, Nanjing, 210037, China. Electronic address:

In this work, we attempted to develop a fluorescent probe for hydrazine in real samples. Accordingly, we designed BER9-HZ to fulfill the set rules as solubility, anti-interference capability and functional compatibility. The selected reporting group BER9 dissolved 100% within 10 min, which indicated much better solubility than Berberine. Read More

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Coping strategies in health care providers as second victims: A systematic review.

Int Nurs Rev 2021 Jun 12. Epub 2021 Jun 12.

Fundamental Care and Medical-Surgical Nursing Department, School of Nursing, L'Hospitalet de Llobregat, University of Barcelona, Barcelona, Spain.

Aim: To analyze personal and organizational strategies described in the literature for dealing with the second victim phenomenon among healthcare providers.

Background: The second victim phenomenon involves many associated signs and symptoms, which can be physical, psychological, emotional, or behavioral. Personal and organizational strategies have been developed to deal with this phenomenon. Read More

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Monte Carlo determination of dose coefficients at different developmental stages of zebrafish (Danio rerio) in experimental condition.

J Environ Radioact 2021 Jun 8;237:106667. Epub 2021 Jun 8.

State Key Laboratory of Radiation Medicine and Protection, School of Radiation Medicine and Protection, Soochow University, Suzhou, 215123, China; Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions. Electronic address:

The release of liquid effluent of nuclear power into aquatic system increases with the rapid development of nuclear facilities in coastal and inland regions. Aquatic model animals are very important for the study of the radiation hazards to non-human biota in water environment and its extrapolation of dose-effect relationship to human models. However, the study of the radiation dose rate calculation model of the aquatic animal zebrafish is still on the homogeneous isotropic model used for the protection of the environment. Read More

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The effects of multi-echo fMRI combination and rapid T*-mapping on offline and real-time BOLD sensitivity.

Neuroimage 2021 Jun 8;238:118244. Epub 2021 Jun 8.

Department of Electrical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands; Department of Research and Development, Epilepsy Centre Kempenhaeghe, Heeze, the Netherlands; School for Mental Health and Neuroscience, Maastricht, the Netherlands; Laboratory for Clinical and Experimental Neurophysiology, Neurobiology and Neuropsychology, Ghent University Hospital, Ghent, Belgium; Department of Neurology, Maastricht University Medical Center, Maastricht, the Netherlands.

A variety of strategies are used to combine multi-echo functional magnetic resonance imaging (fMRI) data, yet recent literature lacks a systematic comparison of the available options. Here we compare six different approaches derived from multi-echo data and evaluate their influences on BOLD sensitivity for offline and in particular real-time use cases: a single-echo time series (based on Echo 2), the real-time T*-mapped time series (T*FIT) and four combined time series (T*-weighted, tSNR-weighted, TE-weighted, and a new combination scheme termed T*FIT-weighted). We compare the influences of these six multi-echo derived time series on BOLD sensitivity using a healthy participant dataset (N = 28) with four task-based fMRI runs and two resting state runs. Read More

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Isoprenoid emissions from natural vegetation increased rapidly in eastern China.

Environ Res 2021 Jun 8;200:111462. Epub 2021 Jun 8.

School of Environmental Science and Engineering, Shandong University, Qingdao, 266237, China.

An accurate local biogenic volatile organic compound (BVOC) emission inventory in Shandong Province is crucial for air pollution control in Shandong and the Beijing-Tianjin-Hebei region, China. We estimated the multi-year isoprenoid emissions from natural vegetation in Shandong Province at a spatial resolution of 4 km × 4 km using the MEGAN2.1 model. Read More

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