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Does Alt-RAMEC protocol and facemask treatment affect dentoalveolar structures?

Angle Orthod 2021 Apr 12. Epub 2021 Apr 12.

Objectives: To evaluate dentoalveolar changes immediately after the alternate rapid maxillary expansion and constriction (Alt-RAMEC) protocol and facemask (FM) treatment using cone-beam computed tomography images.

Materials And Methods: Cone-beam computed tomography images of 20 patients (mean age = 9.64 ± 1. Read More

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Flexor digitorum superficialis muscular activity is more reliable than mentalis muscular activity for rapid eye movement sleep without atonia quantification.

Sleep 2021 Apr 12. Epub 2021 Apr 12.

Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria.

Study Objectives: To evaluate interrater reliability for artefact correction in the context of semi-automated quantification of rapid eye movement (REM) sleep without atonia (RWA) in the mentalis and flexor digitorum superficialis (FDS) muscles.

Methods: We included video-polysomnographies of 14 subjects with apnea-hypopnea-index in REM sleep (AHIREM)<15/h and 11 subjects with AHIREM≥15/h. Eight subjects had isolated REM sleep behavior disorder. Read More

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Detection of Parkinson's Disease Through Automated Pupil Tracking of the Post-illumination Pupillary Response.

Front Med (Lausanne) 2021 25;8:645293. Epub 2021 Mar 25.

Department of Computer Science and Engineering, University of North Texas, Denton, TX, United States.

Parkinson's disease (PD) is one of the most common neurodegenerative disorders, but it is often diagnosed after the majority of dopaminergic cells are already damaged. It is critical to develop biomarkers to identify the disease as early as possible for early intervention. PD patients appear to have an altered pupillary response consistent with an abnormality in photoreceptive retinal ganglion cells. Read More

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Hungry Bone Syndrome After Living Donor Liver Transplant for Biliary Atresia.

Exp Clin Transplant 2021 Apr;19(4):386-389

From the Department of Pediatric Surgery and Transplantation, Kumamoto University Graduate School of Medical Sciences, Kumamoto, Japan.

Hungry bone syndrome is a rare but potentially lethal complication that is characterized by rapid, severe, long-lasting hypocalcemia and hypophosphatemia secondary to increased bone metabolism. We present a case of hungry bone syndrome after living donor liver transplant for biliary atresia. Following a failed Kasai procedure for biliary atresia, a 5-month-old boy underwent living donor liver transplant with reduced left lateral lobe from his father. Read More

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A deep learning approach to identifying immunogold particles in electron microscopy images.

Sci Rep 2021 Apr 8;11(1):7771. Epub 2021 Apr 8.

Max Planck Florida Institute for Neuroscience, 1 Max Planck Way, Jupiter, FL, 33458, USA.

Electron microscopy (EM) enables high-resolution visualization of protein distributions in biological tissues. For detection, gold nanoparticles are typically used as an electron-dense marker for immunohistochemically labeled proteins. Manual annotation of gold particle labels is laborious and time consuming, as gold particle counts can exceed 100,000 across hundreds of image segments to obtain conclusive data sets. Read More

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Data-driven and coarse-to-fine baseline correction for signals of analytical instruments.

Anal Chim Acta 2021 May 13;1157:338386. Epub 2021 Mar 13.

Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China.

Baseline correction is an indispensable step in the signal processing of chemical analysis instruments. With the increasing demand for on-site applications, a variety of analytical instruments require a more friendly, rapid and adaptive baseline correction method. In this paper, a data-driven and coarse-to-fine (DD-CF) baseline correction scheme mainly based on the empirical mode decomposition (EMD) algorithm is proposed. Read More

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Orthodontic appliances and MR image artefacts: An exploratory in vitro and in vivo study using 1.5-T and 3-T scanners.

Imaging Sci Dent 2021 Mar 29;51(1):63-71. Epub 2021 Jan 29.

Department of Oral and Maxillofacial Radiology, Faculty of Odontology, Malmö University, Malmö, Sweden.

Purpose: The aim of this study was to assess the artefacts of 12 fixed orthodontic appliances in magnetic resonance images obtained using 1.5-T and 3-T scanners, and to evaluate different imaging sequences designed to suppress metal artefacts.

Materials And Methods: In vitro, study casts of 1 adult with normal occlusion were used. Read More

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Examining the Psychological State Analysis Relationship Between Bitcoin Prices and COVID-19.

Front Psychol 2021 22;12:647691. Epub 2021 Mar 22.

School of Economics and Management, Xi'an Technological University, Xi'an, China.

The rapid worldwide spread of COVID-19 forced many countries to enforce complete lockdown and strict quarantine policies. The strict lockdown and quarantine affect the psychological state of people toward cryptocurrency. The current research aims to examine the effect of COVID-19 on Bitcoin prices concerning cumulative deaths and confirmed cases. Read More

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Rapid Discrimination of Halal and Non-halal Pharmaceutical Excipients by Fourier Transform Infrared Spectroscopy and Chemometrics.

J Pharm Bioallied Sci 2020 Nov 5;12(Suppl 2):S752-S757. Epub 2020 Nov 5.

Drug and Herbal Research Center, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.

Introduction: The appendage of "halal" to a product is not just a guarantee that the product is permitted for Muslims, but it has also become favorable lifestyle choice globally. However, the expansion of halal pharmaceutical market was hindered by lack of global halal standards for pharmaceutical ingredients and product integrity analytical methodology.

Objective: This work aimed to explore the possibility of using Fourier-transform infrared (FTIR) spectroscopy and chemometrics to develop multivariate models to authenticate the "halal-ity" of pharmaceutical excipients with controversial halal status (e. Read More

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November 2020

A parametric fitting technique for rapid determination of a skin-dose correction factor for angle of beam incidence during image-guided endovascular procedures.

Proc SPIE Int Soc Opt Eng 2021 Feb 15;11595. Epub 2021 Feb 15.

The State University of New York at Buffalo, Jacobs School of Medicine and Biomedical Sciences, Canon Stroke and Vascular Research Center, 875 Ellicott St., Buffalo, NY 14203.

Skin dose is dependent on the incident beam angle and corrections are needed for accurate estimation of the risk of deterministic effects of the skin. To obtain the angular correction factors (ACF's), EGSnrc Monte Carlo (MC) software was used to calculate the skin dose as a function of incident x-ray beam angle at the center of the field for beam energies from 60 to 120 kVp, field sizes from 5 to 15 cm, and thicknesses of Cu beam filters from 0.2 to 0. Read More

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February 2021

Correction to: Efficient and rapid conversion of human astrocytes and ALS mouse model spinal cord astrocytes into motor neuron-like cells by defined small molecules.

Mil Med Res 2021 Apr 6;8(1):24. Epub 2021 Apr 6.

Research Center for Tissue Repair and Regeneration affiliated to the Medical Innovation Research Division and 4th Medical Center, PLA General Hospital and PLA Medical College, 28 Fu Xing Road, Haidian District, Beijing, 100853, P. R. China.

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Correcting ray distortion in tomographic additive manufacturing.

Opt Express 2021 Mar;29(7):11037-11054

Light-based additive manufacturing techniques enable a rapid transition from object design to production. In these approaches, a 3D object is typically built by successive polymerization of 2D layers in a photocurable resin. A recently demonstrated technique, however, uses tomographic dose patterning to establish a 3D light dose distribution within a cylindrical glass vial of photoresin. Read More

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Correction of resonant optical scanner dynamic aberrations using nodal aberration theory.

Opt Express 2021 Mar;29(7):10346-10363

The rapid oscillation of galvanometric resonant optical scanners introduces linear astigmatism that degrades transverse resolution, and in confocal systems, also reduces signal [V. Akondi et al., Optica 7, 1506, 2020]. Read More

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Bandwidth correction of Swarm GPS carrier phase observations for improved orbit and gravity field determination.

GPS Solut 2021 9;25(2):70. Epub 2021 Mar 9.

Astronomical Institute, University of Bern, Sidlerstrasse 5, 3001 Bern, Switzerland.

Gravity fields derived from GPS tracking of the three Swarm satellites have shown artifacts near the geomagnetic equator, where the carrier phase tracking on the L2 frequency is unable to follow rapid ionospheric path delay changes due to a limited tracking loop bandwidth of only 0.25 Hz in the early years of the mission. Based on the knowledge of the loop filter design, an analytical approach is developed to recover the original L2 signal from the observed carrier phase through inversion of the loop transfer function. Read More

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Correcting notification delay and forecasting of COVID-19 data.

J Math Anal Appl 2021 Mar 30:125202. Epub 2021 Mar 30.

Laboratory of Statistics and Natural Computing - LECON, Statistics Department, UFES, Vitória, Brazil.

Since the first official case of COVID-19 was reported, many researchers around the world have spent their time trying to understand the dynamics of the virus by modeling and predicting the number of infected and deaths. The rapid spread and highly contagiousness motivate the necessity of monitoring cases in real-time, aiming to keep control of the epidemic. As pointed out by [3], some pitfalls like limited infrastructure, laboratory confirmation and logistical problems may cause reporting delay, leading to distortions of the real dynamics of the confirmed cases and deaths. Read More

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In-vitro trabecular bone damage following mono- and bicortical mini implants anchorage in mini-implant assisted rapid palatal expansion (MARPE).

Int Orthod 2021 Mar 30. Epub 2021 Mar 30.

Federal university of Rio de Janeiro, Department of pediatric dentistry and orthodontics, Rio de Janeiro, Brazil. Electronic address:

Objectives: To assess in-vitro trabecular bone damage following mono- and bicortical mini-implant (MI) anchorage in mini-implant assisted rapid palatal expansion (MARPE).

Material And Methods: Sixteen self-drilling MI (four MARPE appliances) were distributed in two groups according to bone insertion (monocortical and bicortical) in bovine rib. The device was activated five times (0. Read More

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Exploring Signals on L5/E5a/B2a for Dual-Frequency GNSS Precise Point Positioning.

Sensors (Basel) 2021 Mar 14;21(6). Epub 2021 Mar 14.

Department of Earth and Space Science and Engineering, York University, Toronto, ON M3J 1P3, Canada.

Due to its nature, Precise Point Positioning (PPP) depends on the GNSS measurements and quality of satellite correction products used to relatively quickly provide precise and accurate positions. With the rapid evolution of Global Navigation Satellite Systems (GNSSs), new frequencies and signals are being broadcast, which have a positive impact on PPP performance. This paper presents, for the first time, a comprehensive analysis of PPP performance from these new GPS, Galileo and BeiDou-2/3 signals, which are not yet commonly used for PPP, with correct mitigation of errors such as the estimation of GPS Block-IIF L5 variations. Read More

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Sensitivity and specificity of CEST and NOE MRI in injured spinal cord in monkeys.

Neuroimage Clin 2021 Mar 23;30:102633. Epub 2021 Mar 23.

Vanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, USA; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, TN, USA. Electronic address:

Purpose: The sensitivity and accuracy of chemical exchange saturation transfer (CEST) and nuclear Overhauser enhancement (NOE) effects for assessing injury-associated changes in cervical spinal cords were evaluated in squirrel monkeys. Multiple interacting pools of protons, including one identified by an NOE at -1.6 ppm relative to water (NOE(-1. Read More

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The embodiment of wastewater data for the estimation of illicit drug consumption in Spain.

Sci Total Environ 2021 Jun 26;772:144794. Epub 2021 Jan 26.

Department of Analytical Chemistry, Nutrition and Food Sciences, Institute of Research in Chemical and Biological Analysis (IAQBUS), Universidade de Santiago de Compostela, Santiago de Compostela, Spain. Electronic address:

Data obtained from wastewater analysis can provide rapid and complementary insights in illicit drug consumption at community level. Within Europe, Spain is an important country of transit of both cocaine and cannabis. The quantity of seized drugs and prevalence of their use rank Spain at the top of Europe. Read More

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Determination of sugar content in Lingwu jujube by NIR-hyperspectral imaging.

J Food Sci 2021 Mar 26. Epub 2021 Mar 26.

School of Food and Wine, Ningxia University, Yinchuan, China.

Near infrared hyperspectral imaging (NIR-HSI) with a spectral range of 900 to 1700 nm was for the first time used to predict the changes of sugar content in Lingwu jujube during storage. Monte Carlo method was adopted to detect outliers, and multiple scattering correction (MSC), standard normal variate transformation (SNV), and Baseline were used to optimize modeling. Competitive adaptive reweighted sampling (CARS), interval variable iterative space shrinkage approach (iVISSA), and interval random frog (IRF) were used to select optimal wavelengths. Read More

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Osmotic demyelination syndrome in patients with non-Hodgkin lymphoma: A case report and literature review.

Int J Neurosci 2021 Mar 25:1-6. Epub 2021 Mar 25.

Department of Neurology and Psychiatry, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México City, México.

Osmotic demyelination syndrome (ODS) is a non-inflammatory process of the central nervous system caused by extracellular osmotic changes, which leads to oligodendrocyte apoptosis and disruption of myelin sheaths, usually affecting patients with underlying systemic conditions that impose susceptibility to osmotic stress. Description of ODS in patients with non-Hodgkin lymphoma (NHL) is limited to a few case reports. Here, we report a 44-year-old man with NHL that had an incidental diagnosis of ODS. Read More

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The 25th Anniversary of Laser Vision Correction in the United States.

Stephen N Joffe

Clin Ophthalmol 2021 17;15:1163-1172. Epub 2021 Mar 17.

History of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Laser Vision Correction (LVC) is an elective, self-pay and safe surgical procedure to correct myopia and hyperopia. Since FDA approval 25 years ago, there have been a progression of technological improvements leading to better outcomes and LVC is now one of the safest surgical procedures. With a potential pool of 50 million patients, 6000 trained ophthalmic surgeons regularly treating in over 1000 centers of which 65% are physician owned. Read More

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Effective Collisional Cross-Section of Small Ions in Gas Phase: Application to Ion Mobility Spectrometry.

Rapid Commun Mass Spectrom 2021 Mar 24:e9090. Epub 2021 Mar 24.

Department of Chemistry, Isfahan University of Technology, Isfahan, 84156-83111, Iran.

Rational: The observed drift times of monoatomic ions, including the alkali ions and halide anions are not fully consistent with their size. When the effect of mass is included through the Mason Schamp's equation, the deviation gets worse so that the trend of the experimental collisional cross sections completely turns opposite to what is expected. This is attributed to the stronger local electric field around the smaller ions. Read More

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Rare case of pancrelipase therapy-induced neutropaenia.

BMJ Case Rep 2021 Mar 22;14(3). Epub 2021 Mar 22.

Internal Medicine, Allegheny Health Network, Pittsburgh, Pennsylvania, USA.

A 61-year-old man was transferred to our facility from an outside hospital due to refractory neutropaenia of unknown aetiology. The patient presented to the referring hospital with a 5-day history of worsening diarrhoea and abdominal pain. Initial lab results at presentation showed severe neutropaenia with an absolute neutrophil count of 0. Read More

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Synthetic CT Generation of the Pelvis in Patients With Cervical Cancer: A Single Input Approach Using Generative Adversarial Network.

IEEE Access 2021 8;9:17208-17221. Epub 2021 Jan 8.

Department of Radiology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA.

Multi-modality imaging constitutes a foundation of precision medicine, especially in oncology where reliable and rapid imaging techniques are needed in order to insure adequate diagnosis and treatment. In cervical cancer, precision oncology requires the acquisition of F-labeled 2-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography (PET), magnetic resonance (MR), and computed tomography (CT) images. Thereafter, images are co-registered to derive electron density attributes required for FDG-PET attenuation correction and radiation therapy planning. Read More

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January 2021

Correcting iron deficiency anemia with iron dextran alters the serum metabolomic profile of the infant Rhesus Monkey.

Am J Clin Nutr 2021 Mar 19. Epub 2021 Mar 19.

Division of Neonatology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.

Background: The effects of infantile iron deficiency anemia (IDA) extend beyond hematological indices and include short- and long-term adverse effects on multiple cells and tissues. IDA is associated with an abnormal serum metabolomic profile, characterized by altered hepatic metabolism, lowered NAD flux, increased nucleoside levels, and a reduction in circulating dopamine levels.

Objectives: The objective of this study was to determine whether the serum metabolomic profile is normalized after rapid correction of IDA using iron dextran injections. Read More

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Changes in central venous to arterial carbon dioxide gap (PCO gap) in response to acute changes in ventilation.

BMJ Open Respir Res 2021 Mar;8(1)

Respiratory and Critical Care (Rcare) Group, Aalborg University, Aalborg, Denmark.

Background: Early diagnosis of shock is a predetermining factor for a good prognosis in intensive care. An elevated central venous to arterial PCO difference (∆PCO) over 0.8 kPa (6 mm Hg) is indicative of low blood flow states. Read More

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