Clin Nucl Med 2021 May 26. Epub 2021 May 26.
From the Department of Nuclear Medicine, Korea Institute of Radiological and Medical Sciences, Seoul Department of Nuclear Medicine, Chungbuk National University Hospital, Cheongju Departments of Nuclear Medicine Neurosurgery, Korea Cancer Center Hospital Division of RI Convergence, Korea Institute of Radiological and Medical Sciences FutureChem Co, Ltd, Seoul, Republic of Korea.
Purpose: The aim of the present study was to obtain information about distribution, radiation dosimetry, toxicity, and pharmacokinetics of O-[18F]fluoromethyl-D-tyrosine (D-18F-FMT), an amino acid PET tracer, in patients with brain tumors.
Patients And Methods: A total of 6 healthy controls (age = 19-25 years, 3 males and 3 females) with brain PET images and radiation dosimetry and 12 patients (median age = 60 years, 6 males and 6 females) with primary (n = 5) or metastatic brain tumor (n = 7) were enrolled. We acquired 60-minute dynamic brain PET images after injecting 370 MBq of D-18F-FMT. Read More