1,266 results match your criteria radiopacity

Effect of the incorporation of silica blow spun nanofibers containing silver nanoparticles (SiO/Ag) on the mechanical, physicochemical, and biological properties of a low-viscosity bulk-fill composite resin.

Dent Mater 2021 Aug 31. Epub 2021 Aug 31.

Universidade Federal de Pernambuco, School of Dentistry, Recife, Pernambuco, Brazil. Electronic address:

Objective: This work aimed at producing silica-blow-spun nanofibers containing silver nanoparticles (SiO/Ag) and investigating the effect of their incorporation in different proportions, with or without pre-treatment with a silane coupling agent, on the mechanical, physicochemical, and biological properties of a commercial composite low-viscosity bulk-fill resin.

Methods: The production of SiO/Ag nanofibers was confirmed by transmission electron microscopy (TEM) and energy dispersive X-ray analysis (EDX). A portion of the produced nanofibers was silanized. Read More

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Spontaneous remission of internal root resorption during orthodontic treatment: A clinical follow-up report.

Am J Orthod Dentofacial Orthop 2021 Aug 24. Epub 2021 Aug 24.

Department of Orthodontics, Juiz de Fora Federal University, Juiz de Fora, Brazil.

Internal root resorption (IRR) is a pathologic process that occurs because of external stimuli that affect the pulp and result in the loss of dentinal tissue. The occurrence of IRR is considered relatively rare, and the etiology is not fully understood, although trauma is believed to be the main etiologic agent. The current study presented a case report of spontaneous remission of an IRR lesion diagnosed during orthodontic treatment. Read More

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Iodine-based contrast staining improves micro-computed tomography of atherosclerotic coronary arteries.

MethodsX 2021 5;8:101297. Epub 2021 Mar 5.

Veterinary Physiology and Pharmacology, Texas A&M University, College Station, TX, USA.

We sought to develop a reversible staining protocol using micro-computed tomography (micro-CT) paired with a radiopaque contrast agent that allows for three-dimensional visualization and characterization of atherosclerotic plaques. Atherosclerotic porcine coronary arteries were dissected from surrounding myocardium and incubated in iohexol at various concentrations and incubation times and then imaged using direct radiography. Line profiles were generated across the artery x-ray to determine effectiveness of the radiopaque contrast agent to penetrate the tissue. Read More

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Biological parameters, discolouration and radiopacity of calcium silicate-based materials in a simulated model of partial pulpotomy.

Int Endod J 2021 Aug 21. Epub 2021 Aug 21.

Department of Endodontics, School of Dentistry, Federal University of Uberlândia, Uberlândia, Brazil.

Aim: To analyse the discolouration, radiopacity, pH and calcium ion release of Biodentine (BD), Bio-C repair (BCR) and Bio-C temp (BCT), as well as their biological effects on human dental pulp cells (hDPCs).

Methodology: Sixty-four extracted bovine incisors were prepared to simulate crown fractures with pulp exposure and open root apex. The roots were filled using a mixture of agar and blood (control), and BD, BCR or BCT were placed over this mixture. Read More

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Development of a bioactive and radiopaque bismuth doped baghdadite ceramic for bone tissue engineering.

Bone 2021 Aug 11;153:116147. Epub 2021 Aug 11.

Tissue Engineering & Biomaterials Research Unit, School of Biomedical Engineering, The University of Sydney, NSW 2006, Australia; ARC Training Centre for Innovative BioEngineering, The University of Sydney, NSW 2006, Australia. Electronic address:

Baghdadite (CaZrSiO, BAG), is a Zr-doped calcium silicate that has outstanding bioactivity both in vitro and in vivo. Bioceramic scaffolds should be sufficiently radiopaque to be distinguishable in vivo from surrounding bone structures. To enhance the radiopacity of BAG, this study investigated the effect of incorporating bismuth ions into its crystalline structure (BiCaZrSiO, x = 0, 0. Read More

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Development of Bone Exostosis Following the Use of a Free Gingival Graft: A 30-Year Case Report and Literature Review.

Int J Periodontics Restorative Dent 2021 Jul-Aug;41(4):539-545

Bone exostosis is defined as a benign overgrowth of bone tissue of unclear origin. Rarely, bone exostosis might develop following soft tissue graft procedures like mucogingival surgical interventions (eg, FGG or subepithelial CTG). This aberration has been mainly associated with surgical trauma or fenestration of the periosteum but is still a matter of debate. Read More

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Functional Properties of Polyurethane Ureteral Stents with PLGA and Papaverine Hydrochloride Coating.

Int J Mol Sci 2021 Jul 19;22(14). Epub 2021 Jul 19.

Centre of Polymer and Carbon Materials of the Polish Academy of Sciences, 34 Marii Skłodowskiej-Curie St., 41-819 Zabrze, Poland.

Despite the obvious benefits of using ureteral stents to drain the ureters, there is also a risk of complications from 80-90%. The presence of a foreign body in the human body causes disturbances in its proper functioning. It can lead to biofilm formation on the stent surface, which may favor the development of urinary tract infections or the formation of encrustation, as well as stent fragmentation, complicating its subsequent removal. Read More

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Microfluidic fabrication of imageable and resorbable polyethylene glycol microspheres for catheter embolization.

J Biomed Mater Res A 2021 Jul 21. Epub 2021 Jul 21.

Biomedical Engineering, Saint Louis University, St Louis, Missouri, USA.

Radiopaque and degradable hydrogel microspheres have a range of potential uses in medicine including proper placement of embolic material during occlusion procedures, acting as inherently embolic materials, and serving as drug carriers that can be located after injection. Current methods for creating radiopaque microspheres are either unable to fully and homogeneously incorporate radiopaque material throughout the microspheres for optimal imaging capabilities, do not result in degradable or fully compressible microspheres, or require elaborate, time-consuming preparation. We used a simple one-step microfluidic method to fabricate imageable, degradable polyethylene glycol (PEG) microspheres of varying sizes with homogenous dispersion of barium sulfate-a biocompatible, high-radiopacity contrast agent. Read More

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[Evaluation of solid pulmonary nodules in patients with bladder cancer with computed tomography based texture analysis method: Is it possible to differentiate metastatic - non-metastatic nodules?]

Tuberk Toraks 2021 Jun;69(2):227-236

Department of Radiology, Dokuz Eylül University Faculty of Medicine, İzmir, Turkey.

Introduction: Solid Pulmonary Nodule (SPN) is defined as parenchymal radiopacity smaller than 3 cm in diameter. Evaluating the metastatic nature of the SPNs detected in the thorax computed tomography (TCT) examination for staging purposes in cancer patients becomes a fundamental problem for the physician. Invasive procedures, additional imaging or follow-up imaging, are often used to differentiate metastatic and non-metastatic nodules. Read More

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Osteoformation potential of an allogenic partially demineralized bone matrix in critical-size defects in the rat calvarium.

Mater Sci Eng C Mater Biol Appl 2021 Aug 26;127:112207. Epub 2021 May 26.

CNRS, UMR 7052 - INSERM U1271, Laboratory of Osteoarticular Biology, Bioengineering and Bioimaging, Universiy of Paris, 10 Avenue de Verdun, 75010 Paris, France; Service of Odontology, Hôpital Pitié-Salpêtrière APHP, U.F.R. of Odontology University of Paris, 47-83 Boulevard de l'Hôpital, 75013 Paris, France. Electronic address:

Allogenic demineralized bone matrix has been developed as a reliable alternative to the autologous bone graft. In the present study, we assessed the osteoformation potential of a partially demineralized bone matrix (PDBM) in a paste form obtained without an added carrier. This formulation included the preparation of cancelous bone from femoral heads after decellularision, delipidation, demineralization in HCl and autoclaving at 121 °C. Read More

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Diagnosis and outcome of nasal polyposis in 23 dogs treated medically or by endoscopic debridement.

Can Vet J 2021 07;62(7):736-742

Endovet Professional Association, Rome, Italy (Bottero, Mussi, Raponi, Ruggiero); I Portoni Rossi Veterinary Hospital, Zola Pedrosa, Bologna, Italy (De Lorenzi).

This study describes the clinical, diagnostic, and pathological characteristics of canine nasal polyps and how they responded to medical, endoscopic, and surgical treatments. The database of a multi-center veterinary endoscopy group was searched from 2010 to 2018. All dogs with a histological diagnosis of nasal polyposis that were undergoing endoscopic investigation (N = 23), were included. Read More

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Synergistic Effect of Bioactive Inorganic Fillers in Enhancing Properties of Dentin Adhesives-A Review.

Polymers (Basel) 2021 Jun 30;13(13). Epub 2021 Jun 30.

Prosthetic Dental Science, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.

Dentin adhesives (DAs) play a critical role in the clinical success of dental resin composite (DRC) restorations. A strong bond between the adhesive and dentin improves the longevity of the restoration, but it is strongly dependent on the various properties of DAs. The current review was aimed at summarizing the information present in the literature regarding the improvement of the properties of DAs noticed after the addition of bioactive inorganic fillers. Read More

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Multifunctional Biodegradable Vascular PLLA Scaffold with Improved X-ray Opacity, Anti-Inflammation, and Re-Endothelization.

Polymers (Basel) 2021 Jun 16;13(12). Epub 2021 Jun 16.

Department of Biomedical Science, CHA University, 335 Pangyo-ro, Bundang-gu, Seongnam-si 13488, Korea.

Poly(L-lactic acid) (PLLA) has been used as a biodegradable vascular scaffold (BVS) material due to high mechanical property, biodegradability, and biocompatibility. However, acidic byproducts from hydrolysis of PLLA reduce the pH after the surrounding implanted area and cause inflammatory responses. As a result, severe inflammation, thrombosis, and in-stent restenosis can occur after implantation by using BVS. Read More

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Nanoscale Strontium-Substituted Hydroxyapatite Pastes and Gels for Bone Tissue Regeneration.

Nanomaterials (Basel) 2021 Jun 19;11(6). Epub 2021 Jun 19.

School of Clinical Dentistry, The University of Sheffield, 19 Claremont Crescent, Sheffield S10 2TA, UK.

Injectable nanoscale hydroxyapatite (nHA) systems are highly promising biomaterials to address clinical needs in bone tissue regeneration, due to their excellent biocompatibility, bioinspired nature, and ability to be delivered in a minimally invasive manner. Bulk strontium-substituted hydroxyapatite (SrHA) is reported to encourage bone tissue growth by stimulating bone deposition and reducing bone resorption, but there are no detailed reports describing the preparation of a systematic substitution up to 100% at the nanoscale. The aim of this work was therefore to fabricate systematic series (0-100 atomic% Sr) of SrHA pastes and gels using two different rapid-mixing methodological approaches, wet precipitation and sol-gel. Read More

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PRF-Solution in Large Sinus Membrane Perforation with Simultaneous Implant Placement-Micro CT and Histological Analysis.

Membranes (Basel) 2021 Jun 10;11(6). Epub 2021 Jun 10.

Department of Pediatric Dentistry, School of Dental Medicine, Tel-Aviv University, Tel-Aviv 6997801, Israel.

Background: The purpose of the study was to analyze the efficacy of platelet-rich fibrin (PRF) as a single augmentation material for complicated cases of maxillary sinus floor elevation, resulting from membrane perforation or previous infections.

Methods: Implant insertion in the posterior region of the maxilla was simultaneously performed with maxillary sinus floor augmentation. Schneiderian membrane elevation can be accompanied by extremely serious sinus membrane perforation, due to accidental tearing or intended incision for mucocele removal. Read More

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Comparative Evaluation of Mineral Trioxide Aggregate Obturation Using Four Different Techniques-A Laboratory Study.

Materials (Basel) 2021 Jun 7;14(11). Epub 2021 Jun 7.

Adelaide Dental School, University of Adelaide, Adelaide, SA 5000, Australia.

This study aimed to compare the density of mineral trioxide aggregate (MTA) as a root canal filling material in the apical 5 mm of artificial root canals. Forty transparent acrylic blocks with 30-degree curved canals were instrumented and allocated into four compaction technique groups ( = 10): Lawaty (hand files); gutta-percha (GP) points; auger (nickel-titanium rotary files in reverse mode); and plugger technique. Filled canals were weighed after setting the MTA to calculate difference in mass. Read More

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Evaluation of curved root canals filled with a new bioceramic sealer: A microcomputed tomographic study using images with different voxel sizes and segmentation methods.

Microsc Res Tech 2021 Jun 28. Epub 2021 Jun 28.

Department of Restorative Dentistry, Sao Paulo State University (UNESP), School of Dentistry, Araraquara, Sao Paulo, Brazil.

The aim of this study was to investigate the filling ability of a new premixed bioceramic sealer in comparison with an epoxy resin-based sealer in curved root canals using different segmentation methods and voxel sizes in micro-CT images. Twelve curved mesial roots of mandibular molars with two separated canals were selected. All root canals were prepared by using HyFlex EDM files size 25/. Read More

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Investigation of a modified hydraulic calcium silicate-based material - Bio-C Pulpo.

Braz Oral Res 2021 16;35:e077. Epub 2021 Jun 16.

Universidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Restorative Dentistry, Piracicaba, SP, Brazil.

This study evaluated the physicochemical, biological, and antimicrobial properties of a new hydraulic calcium silicate-based modified material, and compared it with MTA Repair HP and MTA Angelus. The materials were assessed regarding color luminosity (L), color change, radiopacity, setting time, and ISO 6876:2012 linear flow. Volumetric filling and volume change were evaluated using microcomputed-tomography (µCT). Read More

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A Novel IFITM5 Variant Associated with Phenotype of Osteoporosis with Calvarial Doughnut Lesions: A Case Report.

Calcif Tissue Int 2021 Jun 22. Epub 2021 Jun 22.

Folkhälsan Institute of Genetics, University of Helsinki, P.O. Box 63, FIN-00014, Helsinki, Finland.

Osteogenesis imperfecta (OI) and other decreased bone density disorders comprise a heterogeneous group of heritable diseases with skeletal fragility. Recently, it was discovered that mutations in SGMS2, encoding sphingomyelin synthetase 2, result in aberrant sphingomyelin metabolism and lead to a novel form of OI termed osteoporosis with calvarial doughnut lesions (OP-CDL) with moderate to severe skeletal fragility and variable cranial hyperostotic lesions. This study describes a Japanese family with the skeletal phenotype of OP-CDL. Read More

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Injectable and thermosensitive hydrogels mediating a universal macromolecular contrast agent with radiopacity for noninvasive imaging of deep tissues.

Bioact Mater 2021 Dec 23;6(12):4717-4728. Epub 2021 May 23.

State Key Laboratory of Molecular Engineering of Polymers, Department of Macromolecular Science, Shanghai Stomatological Hospital, Fudan University, Shanghai, 200438, China.

It is very challenging to visualize implantable medical devices made of biodegradable polymers in deep tissues. Herein, we designed a novel macromolecular contrast agent with ultrahigh radiopacity (iodinate content > 50%) via polymerizing an iodinated trimethylene carbonate monomer into the two ends of poly(ethylene glycol) (PEG). A set of thermosensitive and biodegradable polyester-PEG-polyester triblock copolymers with varied polyester compositions synthesized by us, which were soluble in water at room temperature and could spontaneously form hydrogels at body temperature, were selected as the demonstration materials. Read More

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December 2021

Amphiphilic phospholipid-iodinated polymer conjugates for bioimaging.

Biomater Sci 2021 Jul;9(14):5045-5056

Department of Chemistry, North Carolina Agricultural and Technical State University, Greensboro, North Carolina 27411, USA.

Amphiphilic phospholipid-iodinated polymer conjugates were designed and synthesized as new macromolecular probes for a highly radiopaque and biocompatible imaging technology. Bioconjugation of PEG 2000-phospholipids and iodinated polyesters by click chemistry created amphiphilic moieties with hydrophobic polyesters and hydrophilic PEG units, which allowed their self-assemblies into vesicles or spiked vesicles. More importantly, the conjugates exhibited high radiopacity and biocompatibility in in vitro X-ray and cell viability measurements. Read More

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Core-shell structured [email protected]@SiO filler for radiopacity and ultra-low shrinkage dental composite resins.

J Mech Behav Biomed Mater 2021 09 28;121:104593. Epub 2021 May 28.

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Materials Science and Engineering, Donghua University, Shanghai, 201620, PR China.

To overcome the interfacial problem between X-ray radiopaque ZrO fillers and polymer resin in dental composites, monodispersed [email protected]@SiO (SZS) microspheres with narrow size distribution were prepared by a controlled sol-gel method. In the presence of SiO coating layer over [email protected] (SZ) microspheres, they were easily silanized same as SiO microspheres. Ethoxylated bisphenol A dimethacrylate (EBPADMA) with a higher molecular weight and a lower viscosity was used as base resin monomer mixed with a low amount of diluent triethylene glycol dimethacrylate (TEGDMA). Read More

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September 2021

Ultrasound-gated computed tomography coronary angiography: Development of ultrasound transducers with improved computed tomography compatibility.

Med Phys 2021 Aug 11;48(8):4191-4204. Epub 2021 Jul 11.

Department of Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, USA.

Purpose: Cardiovascular disease (CVD) is a leading cause of death worldwide, with coronary artery disease (CAD) accounting for nearly half of all CVD deaths. The current gold standard for CAD diagnosis is catheter coronary angiography (CCA), an invasive, expensive procedure. Computed tomography coronary angiography (CTCA) represents an attractive non-invasive alternative to CCA, however, CTCA requires gated acquisition of CT data during periods of minimal cardiac motion (quiescent periods) to avoid non-diagnostic scans. Read More

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Interaction of Poly L-Lactide and Tungsten Disulfide Nanotubes Studied by in Situ X-ray Scattering during Expansion of PLLA/WSNT Nanocomposite Tubes.

Polymers (Basel) 2021 May 27;13(11). Epub 2021 May 27.

Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, CA 91125, USA.

In situ synchrotron X-ray scattering was used to reveal the transient microstructure of poly(L-lactide) (PLLA)/tungsten disulfide inorganic nanotubes (WSNTs) nanocomposites. This microstructure is formed during the blow molding process ("tube expansion") of an extruded polymer tube, an important step in the manufacturing of PLLA-based bioresorbable vascular scaffolds (BVS). A fundamental understanding of how such a microstructure develops during processing is relevant to two unmet needs in PLLA-based BVS: increasing strength to enable thinner devices and improving radiopacity to enable imaging during implantation. Read More

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Characterization, Antimicrobial Effects, and Cytocompatibility of a Root Canal Sealer Produced by Pozzolan Reaction between Calcium Hydroxide and Silica.

Materials (Basel) 2021 May 27;14(11). Epub 2021 May 27.

Department of Conservative Dentistry, School of Dentistry and Institute of Oral Bioscience, Jeonbuk National University, Jeonju 54896, Korea.

This study aimed to evaluate a newly developed pozzolan-based bioceramic sealer (PZBS) regarding setting time, radiopacity, antibacterial effect, and cytocompatibility. The PZBS was manufactured by mixing calcium hydroxide and silica. The pozzolan reaction was verified by identification of calcium silicate hydrate (C-S-H) using X-ray diffraction analysis. Read More

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Crystallization Behavior and Mechanical Properties of Poly(ε-caprolactone) Reinforced with Barium Sulfate Submicron Particles.

Materials (Basel) 2021 May 2;14(9). Epub 2021 May 2.

Department of Mining-Metallurgy Engineering and Materials Science, POLYMAT, Faculty of Engineering in Bilbao, University of the Basque Country (UPV/EHU), Plaza Torres Quevedo 1, 48013 Bilbao, Spain.

Poly(ε-caprolactone) (PCL) was mixed with submicron particles of barium sulfate to obtain biodegradable radiopaque composites. X-ray images comparing with aluminum samples show that 15 wt.% barium sulfate (BaSO) is sufficient to present radiopacity. Read More

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Radiopacity endowed magnetic nanocomposite with hyperthermia andmineralization potential: a combinatorial therapeutic system for osteosarcoma.

Biomed Mater 2021 May 28;16(4). Epub 2021 May 28.

Department of Polymer Science and Rubber Technology, Cochin University of Science and Technology, Kochi 682022, India.

The development of clinically advanced multifaceted therapeutic materials for osteosarcoma is at the forefront of cancer research. Accordingly, this work presents the design of a multifunctional magnetic nanocomposite composed of maghemite, strontium doped hydroxyapatite and silica nanoparticles prospectively holding indispensable therapeutic features such as magnetic hyperthermia,biomineralization, sustained drug release and intrinsic radiopacity for the treatment of osteosarcoma. The optimal composition has been identified by sequentially modulating the ratio of precursors of the magnetic nanocomposite synthesized by sol-gel technique. Read More

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Radiographic changes in endodontically treated teeth submitted to drowning and burial simulations: is it a useful tool in forensic investigation?

J Forensic Odontostomatol 2021 Apr 30;1(39):9-15. Epub 2021 Apr 30.

Department of Public Health, Stomatology and Forensic Odontology. School of Dentistry of Ribeirão Preto, University of São Paulo - Brazil.

Dental radiographs, endodontic treatment and materials are a source of useful forensic data. The response of dental materials to death-related events are widely studied and provide forensic evidence for experts. This study aimed to analyze the radiographic images of endodontically treated teeth submitted to burial and drowning simulation, verifying its forensic feasibility, applicability and usefulness. Read More

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Lipiodol as an intra-procedural imaging biomarker for liver tumor response to transarterial chemoembolization: Post-hoc analysis of a prospective clinical trial.

Clin Imaging 2021 Oct 18;78:194-200. Epub 2021 May 18.

Department of Radiology and Biomedical Imaging, Yale University School of Medicine, 330 Cedar Street, New Haven, CT 06520, USA. Electronic address:

Background: The use of the ethiodized oil- Lipiodol in conventional trans-arterial chemoembolization (cTACE) ensures radiopacity to visualize drug delivery in the process of providing selective drug targeting to hepatic cancers and arterial embolization. Lipiodol functions as a carrier of chemo drugs for targeted therapy, as an embolic agent, augmenting the drug effect by efflux into the portal veins as well as a predictor for the tumor response and survival.

Purpose: To prospectively evaluate the role of 3D quantitative assessment of intra-procedural Lipiodol deposition in liver tumors on CBCT immediately after cTACE as a predictive biomarker for the outcome of cTACE. Read More

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October 2021

Radiopacity of sodium zirconium cyclosilicate on CT imaging.

CEN Case Rep 2021 May 19. Epub 2021 May 19.

St John's Riverside Hospital, 967 North Broadway, Yonkers, NY, 10701, USA.

A patient who post-operatively develops hyperkalemia is treated with sodium zirconium cyclosilicate (Lokelma), a novel agent used for the treatment of non-life-threatening hyperkalemia with reduced side effects as compared with its predecessors. On CT imaging of the chest, abdomen, and pelvis, a radiopaque fluid is noticed despite the patient not having received any oral or intravenous contrast nor any medications or supplements that may appear radiopaque. Based on previous CT imaging of zirconium-based tooth implants and their radiopaque appearance on images, it is hypothesized that the sodium zirconium cyclosilicate that the patient was administered is the explanation of the radiopacity on CT imaging. Read More

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