Carbohydr Polym 2020 Mar 21;231:115652. Epub 2019 Nov 21.
Institute of Nuclear Physics and Chemistry, China Academy of Engineering Physics, 621900, Mianyang, PR China; Collaborative Innovation Center of Radiation Medicine of Jiangsu, Higher Education Institutions, 215123, Suzhou, PR China; Key Laboratory of Nuclear Medicine and Molecular Imaging of Sichuan Province, 621999, Mianyang, PR China. Electronic address:
Hyaluronan (HA) have been widely used as the ideal biomaterials. It is important to understand their degradation and distribution for better optimization. From a new aspect of using radiotracers, we designed the HA-tyramine-bisphosphonate derivative for dual-labelling with two radionuclides (Tc and I) simultaneously for in vitro and in vivo tracking. Read More