7 results match your criteria rabv exposures

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Evidence of Arctic Fox Survival following Exposure to Rabies Virus.

J Wildl Dis 2021 Nov 23. Epub 2021 Nov 23.

US Department of Agriculture, National Wildlife Research Center, 4101 Laporte Avenue, Fort Collins, Colorado 80521, USA.

The arctic fox variant of the rabies virus (RABV) is enzootic in the circumpolar north. Reports of abortive RABV exposures motivated a retrospective analysis of sera from 41 arctic foxes captured at Karrak Lake in Nunavut, Canada, during 2011-2015. Estimated RABV antibody prevalence among foxes was 14% (95% confidence interval, 7-28%). Read More

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November 2021

Incidence and seroprevalence of rabies virus in humans, dogs and other animal species in Africa, a systematic review and meta-analysis.

One Health 2021 Dec 26;13:100285. Epub 2021 Jun 26.

Virology Department, Centre, Pasteur of Cameroon, Yaounde, Cameroon.

Rabies is transmitted to humans mainly by dogs but also by other animal species. Reliable data on the incidence of Rabies virus (RABV) in humans, dogs, and other animal species in Africa, could be essential in the implementation of a global strategic plan to eliminate the RABV by 2030 as adopted by the WHO, OIE, and FAO. We searched the Pubmed, Embase, Scopus, African Journal Online, and African Index Medicus databases for relevant studies that report data on the incidence of RABV in Africa up to February 17, 2020. Read More

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December 2021

Establishment of a Chinese street rabies virus library and its application for detecting neutralizing activity.

Infect Dis Poverty 2018 Dec 5;7(1):117. Epub 2018 Dec 5.

Key Laboratory of Medical Virology, Ministry of Health, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, 102206, China.

Background: The injection of rabies immune globulin (RIG) is of the utmost importance in the management of category III exposures to rabies-suspect animals. Because of the high cost and limited availability of existing RIG, one possible replacement for RIG is monoclonal antibodies (MAbs) against the rabies virus (RABV). Consequently, it is necessary to determine the neutralizing activity of the MAbs against rabies viruses, especially street rabies virus. Read More

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December 2018

Bat rabies in Washington State: Temporal-spatial trends and risk factors for zoonotic transmission (2000-2017).

PLoS One 2018 9;13(10):e0205069. Epub 2018 Oct 9.

Office of Communicable Disease Epidemiology, Washington State Department of Health, Shoreline, Washington, United States of America.

Background: Rabies is a zoonotic viral disease that can affect all mammals. In the United States, the majority of human rabies cases are caused by bats, which are the only known reservoirs for rabies virus (RABV) in Washington State. We sought to characterize bat RABV epidemiology in Washington among bats submitted by the public for RABV testing. Read More

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A Systematic Review of Human Bat Rabies Virus Variant Cases: Evaluating Unprotected Physical Contact with Claws and Teeth in Support of Accurate Risk Assessments.

PLoS One 2016 26;11(7):e0159443. Epub 2016 Jul 26.

The Wistar Institute, Philadelphia, PA, United States of America.

In the United States and Canada, the most recent documented cases of rabies have been attributed to bat rabies viruses (RABV). We undertook this systematic review in an effort to summarize and enhance understanding of the risk of infection for individuals who have been potentially exposed to a suspect or confirmed rabid bat. United States rabies surveillance summaries documented a total of 41 human bat-rabies virus variant verified non-transplant cases between 1990 and 2015. Read More

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Safety and serological response to a matrix gene-deleted rabies virus-based vaccine vector in dogs.

Vaccine 2014 Mar 7;32(15):1716-9. Epub 2014 Feb 7.

Department of Microbiology and Immunology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA, United States; Jefferson Vaccine Center, Thomas Jefferson University, Philadelphia, PA, United States.

Dogs account for the majority of human exposures and deaths due to rabies virus (RABV) worldwide. In this report, we show that a replication-deficient RABV-based vaccine in which the matrix gene is deleted (RABV-ΔM) is safe and induces rapid and potent VNA titers after a single inoculation in dogs. Average VNA titers peaked at 3. Read More

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Lyssavirus infection: 'low dose, multiple exposure' in the mouse model.

Virus Res 2014 Mar 29;181:35-42. Epub 2013 Dec 29.

Wildlife Zoonoses and Vector Borne Diseases Research Group, Animal Health and Veterinary Laboratories Agency, Woodham Lane, New Haw, Surrey KT15 3NB, United Kingdom; Department of Clinical Infections, University of Liverpool, Microbiology and Immunology, United Kingdom.

The European bat lyssaviruses (EBLV-1 and EBLV-2) are zoonotic pathogens present within bat populations across Europe. The maintenance and transmission of lyssaviruses within bat colonies is poorly understood. Cases of repeated isolation of lyssaviruses from bat roosts have raised questions regarding the maintenance and intraspecies transmissibility of these viruses within colonies. Read More

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