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Qiyusanlong Formula Induces Autophagy in Non-Small-Cell Lung Cancer Cells and Xenografts through the mTOR Signaling Pathway.

Evid Based Complement Alternat Med 2021 22;2021:5575453. Epub 2021 May 22.

Institute of Traditional Chinese Medicine of Respiratory Disease Prevention, Anhui University of Chinese Medicine, Hefei, Anhui, China.

Objective: Qiyusanlong (QYSL) formula has been used in the clinic for more than 20 years and has been proved to have pronounced efficacy in the treatment of non-small-cell lung cancer (NSCLC). This work aims to evaluate the molecular mechanism of QYSL formula action on NSCLC, specifically in relation to autophagy induction.

Methods: In vitro, CCK-8 was used to detect the effect of QYSL serum on cell viability in A549 cells. Read More

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