3 results match your criteria qysl

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Qiyusanlong Formula Induces Autophagy in Non-Small-Cell Lung Cancer Cells and Xenografts through the mTOR Signaling Pathway.

Evid Based Complement Alternat Med 2021 22;2021:5575453. Epub 2021 May 22.

Institute of Traditional Chinese Medicine of Respiratory Disease Prevention, Anhui University of Chinese Medicine, Hefei, Anhui, China.

Objective: Qiyusanlong (QYSL) formula has been used in the clinic for more than 20 years and has been proved to have pronounced efficacy in the treatment of non-small-cell lung cancer (NSCLC). This work aims to evaluate the molecular mechanism of QYSL formula action on NSCLC, specifically in relation to autophagy induction.

Methods: In vitro, CCK-8 was used to detect the effect of QYSL serum on cell viability in A549 cells. Read More

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Qiyusanlong decoction suppresses lung cancer in mice via Wnt/β-catenin pathway.

Mol Med Rep 2018 Apr 24;17(4):5320-5327. Epub 2018 Jan 24.

Key Laboratory of Xin An Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei, Anhui 230012, P.R. China.

Lung cancer is one of the most fatal cancers due to its high metastatic rate. Traditional Chinese medicine has been used in cancer patients for decades to improve quality of life and prolong survival time. The present study used a novel Qiyusanlong (QYSL) decoction composed of 10 kinds of Chinese medicine including astragalus membranaceus (Huangqi), polygonatumod oratum (yuzu), scolopendra (tianlong), pberetima (dilong), solanum nigrum (longkui), herbahedyotis (baihushecao), semen coicis (yiyiren), euphorbia helioscopia (zeqi), curcuma longa (eshu) and tendril-leaved fritillary bulb (chuanbei). Read More

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[Qiyusanlong decoction inhibits the level of PD-1/PD-L1 in mice bearing Lewis lung carcinoma].

Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2016 Jun;32(6):770-4

Anhui University of Chinese Medicine, Hefei 230038; Institute of Chinese Medicine for Respiratory Diseases, Anhui Provincial Academy of Chinese Medical Sciences, Hefei 230038, China. *Corresponding author, E-mail:

Objective To investigate the anti-tumor effect of Qiyusanlong decoction (QYSL) in the mice with Lewis lung cancer (LLC) and its effect on the expression of programmed death 1 and programmed death ligand 1 (PD-1/PD-L1). Methods The model of lung cancer subcutaneous allograft was established using LLC cells. The model mice were randomly divided into six groups: a model group, a chemotherapy group, three QYSL groups of high, middle and low doses, and a combined group, each group containing 8 mice. Read More

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