1,328,542 results match your criteria quantitative evaluation

A quantitative evaluation of aerosol generation during supraglottic airway insertion and removal.

Anaesthesia 2021 Jul 20. Epub 2021 Jul 20.

Pain and Critical Care Sciences and School of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, UK.

Many guidelines consider supraglottic airway use to be an aerosol-generating procedure. This status requires increased levels of personal protective equipment, fallow time between cases and results in reduced operating theatre efficiency. Aerosol generation has never been quantitated during supraglottic airway use. Read More

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Reply to the Letter to the Editor: Quantitative evaluation of COVID-19 pneumonia severity by CT pneumonia analysis algorithm using deep learning technology and blood test results.

Tomohisa Okuma

Jpn J Radiol 2021 Jul 21. Epub 2021 Jul 21.

Department of Diagnostic Radiology, Osaka City General Hospital, 2-13-22 Miyakojima-hondori, Miyakojima-ku, Osaka, 534-0021, Japan.

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Identification and Quantification of Bu Shen Yi Sui Capsule by UPLC-LTQ-Orbitrap-MSn and UPLC-QTOF-MS/MS.

J Chromatogr Sci 2021 Jul 21. Epub 2021 Jul 21.

School of Traditional Chinese Medicine, Beijing Key Lab of TCM Collateral Disease Theory Research, Capital Medical University, Beijing 100069, China.

Traditional Chinese medicines (TCMs) have been considered as important alternative therapeutics because of their significant medicinal benefits in specific diseases. Chinese herb formula is characterized by a vast molecule that differs in routine medicines. Due to TCMs chemical complexity, proper quality control has been a great challenge. Read More

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Stem cell therapy for dilated cardiomyopathy.

Cochrane Database Syst Rev 2021 Jul 21;7:CD013433. Epub 2021 Jul 21.

Interdisciplinary Centre for Health Studies CIESAL, Universidad de Valparaíso, Viña del Mar, Chile.

Background: Stem cell therapy (SCT) has been proposed as an alternative treatment for dilated cardiomyopathy (DCM), nonetheless its effectiveness remains debatable.

Objectives: To assess the effectiveness and safety of SCT in adults with non-ischaemic DCM.

Search Methods: We searched CENTRAL in the Cochrane Library, MEDLINE, and Embase for relevant trials in November 2020. Read More

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Optimization for synthesis of silver nanoparticles through response surface methodology using leaf extract of Boswellia sacra and its application in antimicrobial activity.

Environ Monit Assess 2021 Jul 20;193(8):497. Epub 2021 Jul 20.

Department of Chemistry, Aligarh Muslim University, Uttar Pradesh, Aligarh, 202002, India.

In the present work, leaf extract of Boswellia sacra was used as reductant for synthesis of silver nanoparticles (AgNPs). The variables such as volume of Boswellia sacra leaf extract (1%), volume of silver nitrate (1 mM), and temperature were optimized by response surface methodology via Box-Behnken design for the synthesis of AgNPs. Design-Expert software generated the optimum conditions for the highest yield of silver nanoparticles as 8 mL of 1 mM AgNO, 8 mL of 1% Boswellia sacra leaf extract, and temperature = 55 °C. Read More

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Effectiveness of the Elos 2.0 prevention programme for the reduction of problem behaviours and promotion of social skills in schoolchildren: study protocol for a cluster-randomized controlled trial.

Trials 2021 Jul 20;22(1):468. Epub 2021 Jul 20.

Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil.

Background: Early interventions benefit the mental health, academic performance and productivity of children and adolescents throughout their life. The present study protocol will evaluate the effectiveness of the Elos 2.0 Programme, which is a version adapted for Brazil by the Ministry of Health, in reducing problem behaviours (e. Read More

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Identification of novel antioxidant gene signature to predict the prognosis of patients with gastric cancer.

World J Surg Oncol 2021 Jul 20;19(1):219. Epub 2021 Jul 20.

Department of Oncology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.

Background: Gastric cancer (GC) commonly relates to dismal prognosis and lacks efficient biomarkers. This study aimed to establish an antioxidant-related gene signature and a comprehensive nomogram to explore novel biomarkers and predict GC prognosis.

Methods: Clinical and expression data of GC patients were extracted from The Cancer Genome Atlas database. Read More

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Physiologically Based Pharmacokinetic Modeling of Transporter-Mediated Hepatic Disposition of Imaging Biomarker Gadoxetate in Rats.

Mol Pharm 2021 Jul 20. Epub 2021 Jul 20.

Centre for Applied Pharmacokinetic Research, School of Health Sciences, University of Manchester, Manchester M13 9PL, U.K.

Physiologically based pharmacokinetic (PBPK) models are increasingly used in drug development to simulate changes in both systemic and tissue exposures that arise as a result of changes in enzyme and/or transporter activity. Verification of these model-based simulations of tissue exposure is challenging in the case of transporter-mediated drug-drug interactions (tDDI), in particular as these may lead to differential effects on substrate exposure in plasma and tissues/organs of interest. Gadoxetate, a promising magnetic resonance imaging (MRI) contrast agent, is a substrate of organic-anion-transporting polypeptide 1B1 (OATP1B1) and multidrug resistance-associated protein 2 (MRP2). Read More

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The Q-Pass Index: A Multifactorial IMUs-Based Tool to Assess Passing Skills in Basketball.

Sensors (Basel) 2021 Jul 5;21(13). Epub 2021 Jul 5.

Department of Physical Activity and Sport, Faculty of Sport Sciences, University of Murcia, 30720 Murcia, Spain.

Despite being a key sport-specific characteristic in performance, there is no practical tool to assess the quality of the pass in basketball. The aim of this study is to develop a tool (the quality-pass index or Q-Pass) able to deliver a quantitative, practical measure of passing skills quality based on a combination of accuracy, execution time and pass pattern variability. Temporal, kinematics and performance parameters were analysed in five different types of passes (chest, bounce, crossover, between-the-leg and behind-the-back) using a field-based test, video cameras and body-worn inertial sensors (IMUs). Read More

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Received Signal Strength Fingerprinting-Based Indoor Location Estimation Employing Machine Learning.

Sensors (Basel) 2021 Jul 5;21(13). Epub 2021 Jul 5.

Department of Informatics, University of Piraeus, 185 34 Pireas, Greece.

The fingerprinting technique is a popular approach to reveal location of persons, instruments or devices in an indoor environment. Typically based on signal strength measurement, a power level map is created first in the learning phase to align with measured values in the inference. Second, the location is determined by taking the point for which the recorded received power level is closest to the power level actually measured. Read More

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Biosensors for European Zoonotic Agents: A Current Portuguese Perspective.

Sensors (Basel) 2021 Jul 2;21(13). Epub 2021 Jul 2.

[email protected], School of Engineering, Polytechnic Institute of Porto, 4249-015 Porto, Portugal.

Emerging and recurrent outbreaks caused by zoonotic agents pose a public health risk. They result in morbidity and mortality in humans and significant losses in the livestock and food industries. This highlights the need for rapid surveillance methods. Read More

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Estimating Vehicle and Pedestrian Activity from Town and City Traffic Cameras.

Sensors (Basel) 2021 Jul 3;21(13). Epub 2021 Jul 3.

Data Science Campus, Office for National Statistics, Newport, South Wales NP10 8XG, UK.

Traffic cameras are a widely available source of open data that offer tremendous value to public authorities by providing real-time statistics to understand and monitor the activity levels of local populations and their responses to policy interventions such as those seen during the COrona VIrus Disease 2019 (COVID-19) pandemic. This paper presents an end-to-end solution based on the Google Cloud Platform with scalable processing capability to deal with large volumes of traffic camera data across the UK in a cost-efficient manner. It describes a deep learning pipeline to detect pedestrians and vehicles and to generate mobility statistics from these. Read More

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Construct validity of the Suboptimal Health Status Questionnaire-25 in a Ghanaian population.

Health Qual Life Outcomes 2021 Jul 19;19(1):180. Epub 2021 Jul 19.

Center for Precision Health, Edith Cowan University, 270 Joondalup Drive, Joondalup, WA, Australia.

Background: The Suboptimal Health Status Questionnaire-25 (SHS-Q-25) developed to measure Suboptimal Health Status has been used worldwide, but its construct validity has only been tested in the Chinese population. Applying Structural Equation Modelling, we investigate aspects of the construct validity of the SHS-Q-25 to determine the interactions between SHS subscales in a Ghanaian population.

Methods: The study involved healthy Ghanaian participants (n = 263; aged 20-80 years; 63% female), who responded to the SHSQ-25. Read More

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Taste sensitivity in healthy adults: gustatory test validation and observational study.

J Biol Regul Homeost Agents 2021 Mar-Apr;35(2 Suppl. 1):173-180

Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, Dental Clinic, Department of Oral Medicine, University of Brescia, Brescia, Italy.

Gustatory sensitivity has important biological functions and taste disorders are generally difficult to diagnose and treat. The aim of this study was to investigate taste sensitivity on a sample of adult healthy patients through the validation and administration of a gustatory test, to describe a possible baseline of reference. A gustatory test was performed following a standardized protocol, using primary flavors solutions at 4 known increasing concentrations for a total of 16 sapid solutions. Read More

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[Quantitative evaluation of printing accuracy of multi-color and multi-hardness three-dimensional printing dental model with photopolymer jetting].

Zhonghua Kou Qiang Yi Xue Za Zhi 2021 Jul;56(7):652-658

Center of Digital Dentistry, Faculty of Prosthodontics, Peking University School and Hospital of Stomatology & National Center of Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Laboratory for Digital and Material Technology of Stomatology & Research Center of Engineering and Technology for Computerized Dentistry Ministry of Health & Beijing Key Laboratory of Digital Stomatology, Beijing 100081, China.

To quantitatively evaluate the accuracy of multi-color and multi-hardness dental models printed by using the photopolymer jetting (PJ) technology, and to provide protocol for the clinical application. A maxillary partially edentulous (Kennedy class Ⅱ subclass 1) standard digital model obtained through scanning and processing was selected as reference data. Five monochromatic DLP (digital light processing) models with single hardness were printed by printer DLP-800d based on DLP technology (DLP group), and five multi-color and multi-hardness PJ models were printed by printer J300Plus based on PJ technology (PJ group). Read More

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Interobserver Agreement in Semi-Quantitative Scale-Based Interpretation of Chest Radiographs in COVID-19 Patients.

Med Sci Monit 2021 Jul 18;27:e931277. Epub 2021 Jul 18.

Department of Radiology, Medical Centre for Postgraduate Education, Warsaw, Poland.

BACKGROUND The chest X-ray is the most available imaging modality enabling semi-quantitative evaluation of pulmonary involvement. Parametric evaluation of chest radiographs in patients with SARS-CoV-2 infection is crucial for triage and therapeutic management. The CXR Score (Brixia Score), SARI CXR Severity Scoring System, and Radiographic Assessment of Lung Edema (RALE), proposed to evaluate SARS-CoV-2 infiltration of the lungs, were analyzed for interobserver agreement. Read More

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Ultrasonic characterization of localized passive elastic properties of human pennate muscle with a single-probe setup.

Ultrasonics 2021 Jul 8;116:106512. Epub 2021 Jul 8.

Department of Ultrasonography, Shenzhen Hospital of Guangzhou University of Chinese Medicine, Shenzhen 518034, China.

Quantitative evaluation of passive elastic properties of an individual skeletal muscle in vivo is among the major challenges of biomechanics, and its clinical application is severely limited. By combining shear-wave elastography (SWE) and B-mode imaging techniques, this study develops a novel non-invasive method to measure the local elastic modulus-fascicle strain curve of human pennation muscle during passive stretching using a single probe. Physiologically meaningful parameters are estimated and compared in subjects with different ages or pathological conditions. Read More

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Design and validation of a food frequency questionnaire to assess the dietary intake for adults in pastoral settings in Northern Tanzania.

BMC Res Notes 2021 Jul 17;14(1):274. Epub 2021 Jul 17.

Department of Epidemiology and Biostatistics, Muhimbili University of Health and Allied Sciences, Dar-Es-Salaam, Tanzania.

Objective: Food frequency questionnaires are widely used as a dietary assessment tool in nutritional epidemiology to determine the relationship between diet and diseases. In Tanzania, there are several cultural variations in food intake which makes it necessary to design and validate a culture-specific food frequency questionnaire (CFFQ). Therefore, we designed a 27-items CFFQ and examine its validity in pastoral communities. Read More

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Embedding qualitative research in randomised controlled trials to improve recruitment: findings from two recruitment optimisation studies of orthopaedic surgical trials.

Trials 2021 Jul 17;22(1):461. Epub 2021 Jul 17.

Department of Health Sciences, York Trials Unit, University of York, York, YO10 5DD, UK.

Background: Recruitment of patients is one of the main challenges when designing and conducting randomised controlled trials (RCTs). Trials of rare injuries or those that include surgical interventions pose added challenges due to the small number of potentially eligible patients and issues with patient preferences and surgeon equipoise. We explore key issues to consider when recruiting to orthopaedic surgical trials from the perspective of staff and patients with the aim of informing the development of strategies to improve recruitment in future research. Read More

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ARPEGGIO: Automated Reproducible Polyploid EpiGenetic GuIdance workflOw.

BMC Genomics 2021 Jul 17;22(1):547. Epub 2021 Jul 17.

SIB Swiss Institute of Bioinformatics, University of Zurich, Zurich, Switzerland.

Background: Whole genome duplication (WGD) events are common in the evolutionary history of many living organisms. For decades, researchers have been trying to understand the genetic and epigenetic impact of WGD and its underlying molecular mechanisms. Particular attention was given to allopolyploid study systems, species resulting from an hybridization event accompanied by WGD. Read More

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Stakeholder perspectives on barriers and enablers to recruiting anxious children undergoing day surgery under general anaesthetic: a qualitative internal pilot study of the MAGIC randomised controlled trial.

Trials 2021 Jul 16;22(1):458. Epub 2021 Jul 16.

School of Clinical Dentistry, University of Sheffield, 19 Claremont Crescent, Sheffield, S10 2TA, UK.

Background: The 'Melatonin for Anxiety prior to General anaesthesia In Children' (MAGIC) trial was designed to compare midazolam and melatonin as pre-medications for anxious children (aged five to fourteen), undergoing day-case surgical procedures under general anaesthesia. Low recruitment is a challenge for many trials, particularly paediatric trials and those in 'emergency' settings. A qualitative study as part of MAGIC aimed to gather stakeholder perspectives on barriers and enablers to recruitment. Read More

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Psychometric testing of the Iranian version of the TeamSTEPPS teamwork perception questionnaire: a cross-cultural validation study.

BMC Health Serv Res 2021 Jul 17;21(1):705. Epub 2021 Jul 17.

Chung-Ang University, Red Cross College of Nursing, Seoul, Republic of Korea.

Background: The use of validated questionnaires to assess the perception of teamwork can be an early step in improving team training activities. Team-STEPPS® Teamwork Perception Questionnaire (T-TPQ) has been adapted and validated for hospital setting use in several countries. Due to linguistic and cultural differences, there is need to test the psychometrics of the adapted versions. Read More

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Novel approach for large-scale monitoring of submerged aquatic vegetation - a nationwide example from Sweden.

Integr Environ Assess Manag 2021 Jul 16. Epub 2021 Jul 16.

Department of Marine Sciences, University of Gothenburg, Gothenburg, Sweden.

According to the EU Habitats directive, the Water Framework Directive and the Marine Strategy Framework Directive, member states are required to map, monitor and evaluate changes in quality and areal distribution of different marine habitats and biotopes to protect more effectively the marine environment. Submerged aquatic vegetation (SAV) is one of the key indicators of ecological status of coastal ecosystems, and therefore widely used in reporting related to these directives. Environmental monitoring of the areal distribution of SAV is lacking in Sweden, due to the challenges of large-scale monitoring using traditional small-scale methods. Read More

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[Linguistic adaptation and validation of the voice handicap index (VHI)-30 in patients with dysphonia into Russian].

Vestn Otorinolaringol 2021 ;86(3):20-27

Belarusian Medical Academy of Postgraduate Education, Minsk, Republic of Belarus.

Purpose of the study is to assess the internal consistency, reliability of retesting and clinical reliability of the Russian version of the Voice Handicap Index (VHI)-30 questionnaire.

Material And Methods: It is prospective observational study. The original English version of the VHI-30 questionnaire was translated into Russian by two independent researchers (professional translators). Read More

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[Features of bacterial microbiota in acute purulent otitis media in children].

Vestn Otorinolaringol 2021 ;86(3):4-8

Morozovskaya Pediatric Municipal Clinical Hospital, Moscow, Russia.

Purpose Of The Study: The purpose is to study the spectrum of bacterial pathogens that cause acute purulent otitis media (APOM) in children of the Moscow region in modern conditions and assess their sensitivity to the main groups of antibiotics.

Material And Methods: The study included 1.864 children who underwent examination and received treatment in the otorhinolaryngological department of Morozovskaya Pediatric Municipal Clinical Hospital in the period from 01 July 2018 to 31 June 2020 with a diagnosis of APOM. Read More

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A Few Considerations on Quantitative Evaluation of Hypoechogenicity of the Lateral Collateral Ligament of the Knee.

J Ultrasound Med 2021 Jul 15. Epub 2021 Jul 15.

Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Bei-Hu Branch and National Taiwan University College of Medicine, Taipei, Taiwan.

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[Results of 10 years of the Colorectal Cancer Prevention Program in the Valencian Community.]

Rev Esp Salud Publica 2021 Jul 21;95. Epub 2021 Jul 21.

Dirección General de Salud Pública y Adicciones. Conselleria de Sanidad Universal y Salud Pública. Generalitat Valenciana. España.

Objective: The population-based Program for the Prevention of Colorectal Cancer (PPCRC) was implemented in 2005 in the Valencian Community, following the guidelines of the European Union. To achieve the desired effectiveness in these programs, it is necessary to achieve a series of requirements, assessable through the program indicators. The objective of this study was to analyze the evolution of the program indicators from 2006 to 2016. Read More

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Teledentistry-based Program to Improve Oral Hygiene Indicators in Rural Pakistan-A Protocol.

J Contemp Dent Pract 2021 Apr 1;22(4):406-411. Epub 2021 Apr 1.

Centre of Clinical Research, Telemedicine and Telepharmacy, School of Medicinal and Health Products Sciences, University of Camerino, Macerta, Italy.

Aim: The primary aim of this research protocol is to secure funding to initiate a teledentistry pilot project in order to improve the oral hygiene conditions of the most vulnerable population of rural Sindh in Pakistan, through hands-on training of 1,000 lady health workers by dentists and community dentistry specialists of other colleges led by Jinnah Medical and Dental College.

Materials And Methods: Training courses on digital health consultation would be given to participating healthcare workers. The trainees would be trained on all aspects of dental hygiene including precautions, tooth brushing techniques, and oral care. Read More

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The Low Window Technique: Comparison between Manual and CAD/CAM-guided Design.

J Contemp Dent Pract 2021 Apr 1;22(4):400-405. Epub 2021 Apr 1.

Department of Cariology and Comprehensive Care, New York University College of Dentistry, New York, United States.

Aim: The aim of this bench study was to provide quantitative data addressing the difference between the manual low window design and the corresponding computer-aided design and computer-aided manufacturing (CAD/CAM)-guided design.

Materials And Methods: Five cone-beam computed tomography (CBCT) scans of as many patients (two males and three females, age range: 61-78 years) with partially edentulous maxilla to be rehabilitated through sinus augmentation, one- or two-step implant placement, and implant-supported prostheses were used to 3D-print the corresponding five maxillary stereolithographic models. Five independent highly skilled maxillofacial surgeons, who were provided with the patients' orthopantomographs, drew on the models the access windows for sinus augmentation according to the "high" (standard) and the low window design both by free-hand and using a surgical guide prepared by computer-guided design. Read More

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