15,846 results match your criteria quadriceps muscles


HoxD transcription factors define monosynaptic sensory-motor specificity in the developing spinal cord.

Development 2021 Jun 15;148(12). Epub 2021 Jun 15.

Neural Connectivity Development in Physiology and Disease Laboratory, Burke Neurological Institute, White Plains, NY 10605, USA.

The specificity of monosynaptic connections between proprioceptive sensory neurons and their recipient spinal motor neurons depends on multiple factors, including motor neuron positioning and dendrite morphology, axon projection patterns of proprioceptive sensory neurons in the spinal cord, and the ligand-receptor molecules involved in cell-to-cell recognition. However, with few exceptions, the transcription factors engaged in this process are poorly characterized. Here, we show that members of the HoxD family of transcription factors play a crucial role in the specificity of monosynaptic sensory-motor connections. Read More

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Effects of TheraBand and Theratube Eccentric Exercises on Quadriceps Muscle Strength and Muscle Mass in Young Adults.

Biomed Res Int 2021 25;2021:5560144. Epub 2021 May 25.

Rehabilitation Research Chair, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.

Purpose: This study was aimed at comparing the effects of TheraBand and theratube eccentric exercises on quadriceps muscle strength in young adults.

Methods: Thirty young adults (19 females, 11 males) participated in this pretest-posttest experimental study. Participants were randomly assigned to one of the two groups: TheraBand and theratube groups. Read More

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Skeletal muscle mitochondrial adaptations induced by long-term cigarette smoke exposure.

Am J Physiol Endocrinol Metab 2021 06 14. Epub 2021 Jun 14.

Department of Kinesiology, University of Massachusetts Amherst, United States.

Because patients with Chronic Obstructive Pulmonary Disease (COPD) are often physically inactive, it is still unclear whether the lower respiratory capacity in the locomotor muscles of these patients is due to cigarette smoking per se or is secondary to physical deconditioning. Accordingly, the purpose of this study was to examine mitochondrial alterations in the quadriceps muscle of 10 mice exposed to 8-months of cigarette smoke, a sedentary mouse model of emphysema, and 9 control mice, using immunoblotting, spectrophotometry, and high-resolution respirometry in permeabilized muscle fibers. Mice exposed to smoke displayed a two-fold increase in the oxidative stress marker, 4-HNE, (p < 0. Read More

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Reliability and validity of a standardised ultrasound examination protocol to quantify vastus lateralis muscle.

J Rehabil Med 2021 Jun 14. Epub 2021 Jun 14.

Cardiology, Angiology, Pneumonology, Medical Clinic, University Hospital of Heidelberg, Heidelberg, Germany. E-mail:

Objective: To evaluate the reliability and validity of a standardized ultrasound examination protocol for measuring vastus lateralis muscle size.

Design: Prospective cohort study.

Subjects: Sixteen staff members of the university hospital of Heidelberg. Read More

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Diagnosing sarcopenia: functional perspectives and a new algorithm from the ISPRM special interest group on sarcopenia.

J Rehabil Med 2021 Jun 14. Epub 2021 Jun 14.

Physical and Rehabilitation Medicine, Hacettepe University Medical School, Ankara, Turkey. E-mail:

Sarcopenia is an important public health problem, characterized by age-related loss of muscle mass and muscle function. It is a precursor of physical frailty, mobility limitation, and premature death. Although muscle loss is mainly due to the loss of type II muscle fibres, progressive loss of motor neurones is thought to be the primary underlying factor. Read More

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Effects of Hip Flexion on Knee Extension and Flexion Isokinetic Angle-Specific Torques and HQ-Ratios.

Sports Med Open 2021 Jun 12;7(1):41. Epub 2021 Jun 12.

Institute of Movement and Training Science I, University of Leipzig, Jahnallee 59, 04109, Leipzig, Germany.

Background And Methods: During isokinetic knee strength testing, the knee flexion angles that correspond to the measured torque values are rarely considered. Additionally, the hip flexion angle during seated testing diverges from that in the majority of daily life and sporting activities. Limited information concerning the influence of hip angle, muscle contraction mode, and velocity on the isokinetic knee strength over the entire range of motion (ROM) is available. Read More

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Volume and T2 relaxation time measurements of quadriceps femoris and hamstring muscles are reliable and reproducible.

Turk J Med Sci 2021 Jun 13. Epub 2021 Jun 13.

Background/aim: Volume and T2 relaxation time measurements of the skeletal muscle provide quantitative information. We aimed to evaluate the inter-observer reliability and the intra-observer reproducibility of measurements of volumes and T2 relaxation times of the quadriceps femoris and the hamstring muscles.

Materials And Methods: A cross-sectional reliability study was conducted on ten recreational athletes. Read More

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Relationship of the knee extensor strength but not the quadriceps femoris muscularity with sprint performance in sprinters: a reexamination and extension.

BMC Sports Sci Med Rehabil 2021 Jun 10;13(1):67. Epub 2021 Jun 10.

Faculty of Sport Science, Nippon Sport Science University, Shiga, Kusatsu, Japan.

Purpose: This study examined the relationships of knee extensor strength and quadriceps femoris size with sprint performance in sprinters.

Methods: Fifty-eight male sprinters and 40 body size-matched male non-sprinters participated in this study. The knee extensor isometric and isokinetic strengths were measured using a dynamometer. Read More

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Differences in fatigability of vastus medialis muscle between patients with limb symmetry index of <90% and ≥90% after chronic anterior cruciate ligament reconstruction.

Knee 2021 Jun 7;31:39-45. Epub 2021 Jun 7.

Department of Rehabilitation Medicine, Wakayama Medical University, Wakayama City, Wakayama 641-8509, Japan. Electronic address:

Background: A limb symmetry index (LSI) of ≥90% for the quadriceps is recommended for return to sports activity after anterior cruciate ligament reconstruction (ACLR). However, there is no information on differences in muscle fatigability between patients with LSI of <90% and ≥90%. The aim of this study was to assess the difference in quadriceps muscle fatigability on the involved side between post-ACLR patients with LSI of <90% and ≥90%. Read More

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Assessment of Muscle Volume Using Magnetic Resonance Imaging (MRI) in Football Players after Hamstring Injuries.

Eur J Sport Sci 2021 Jun 10:1-17. Epub 2021 Jun 10.

Institute for Diagnostic and Interventional Radiology, Goethe University Frankfurt, Frankfurt am Main, Germany.

Muscle injuries of the hamstrings are among the most frequent in football and a main cause for significant time away from training and competition. The purpose of this study was to prospectively evaluate the loss of muscle volume in recreational football players three and six weeks after initial trauma. We hypothesized that significant muscle volume loss occurs within 6 weeks after the initial injury event. Read More

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Distinct patterns of spasticity and corticospinal connectivity following complete spinal cord injury.

J Physiol 2021 Jun 9. Epub 2021 Jun 9.

Shirley Ryan AbilityLab, Chicago, Illinois, 60611.

Key Points: Damage to corticospinal axons have implications for the development of spasticity following spinal cord injury (SCI). Here, we examined to which extent residual corticospinal connections and spasticity are present in muscles below the injury (quadriceps femoris and soleus) in humans with motor complete thoracic SCI. We found three distinct sub-groups of people: participants with spasticity and corticospinal responses in the quadriceps femoris and soleus, participants with spasticity and corticospinal responses in the quadriceps femoris only, and participants with no spasticity or corticospinal responses in either muscle. Read More

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Effects of Neuromuscular Electrical Stimulation on Quadriceps Muscle Strength and Mass in Healthy Young and Older Adults: A Scoping Review.

Phys Ther 2021 Jun 9. Epub 2021 Jun 9.

Department of Physical Education and Sport Sciences, Faculty of Literature and Human Sciences, Lorestan University, Khoramabad, Iran.

Objective: Although neuromuscular electrical stimulation (NMES) has been used as a safe and relevant complement to voluntary resistance training, its effectiveness in increasing quadriceps femoris muscle strength and mass in healthy young and older adults has not been determined. The aim of this scoping review was to assess the effects of NMES on quadriceps muscle strength and mass in healthy young and older adults.

Methods: CENTRAL, Pedro, MEDLINE, PubMed were searched from inception to September 2019. Read More

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The anatomical, electrophysiological and histological observations of muscle contraction units in rabbits: a new perspective on nerve injury and regeneration.

Neural Regen Res 2022 Jan;17(1):228-232

Department of Trauma and Orthopedics, Peking University People's Hospital; Key Laboratory of Trauma and Neural Regeneration (Peking University), Ministry of Education; Trauma Center, Peking University People's Hospital; National Trauma Medical Center, Beijing, China.

In the conventional view a muscle is composed of intermediate structures before its further division into microscopic muscle fibers. Our experiments in mice have confirmed this intermediate structure is composed of the lamella cluster formed by motor endplates, the innervating nerve branches and the corresponding muscle fibers, which can be viewed as an independent structural and functional unit. In this study, we verified the presence of these muscle construction units in rabbits. Read More

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January 2022

The impact of ultrasound-guided transmuscular quadratus lumborum block combined with local infiltration analgesia for arthroplasty on postoperative pain relief.

J Clin Anesth 2021 Jun 4;73:110372. Epub 2021 Jun 4.

Department of Anesthesiology, West China Hospital, Sichuan University, No. 37 Wainan Guoxue Road, Chengdu 610041, China. Electronic address:

Study Objective: This study aimed to evaluate the efficacy of ultrasound-guided transmuscular quadratus lumborum block (QLB) combined with local infiltration analgesia (LIA) for pain management and recovery in patients who have undergone total hip arthroplasty (THA) via a posterolateral approach.

Design: This was a prospective, randomized controlled trial.

Setting: We collected data in the preoperative area, operating room, and bed ward. Read More

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Heterogeneity of the strength response to progressive resistance exercise training in older adults: Contributions of muscle contractility.

Exp Gerontol 2021 Jun 4;152:111437. Epub 2021 Jun 4.

Ohio Musculoskeletal and Neurological Institute, Ohio University, Athens, OH, USA; Department of Biomedical Sciences, Ohio University, Athens, OH, USA. Electronic address:

Background: Older adults display wide individual variability (heterogeneity) in the effects of resistance exercise training on muscle strength. The mechanisms driving this heterogeneity are poorly understood. Understanding of these mechanisms could permit development of more targeted interventions and/or improved identification of individuals likely to respond to resistance training interventions. Read More

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Do the quadriceps and hamstring muscles have an effect on patella stability in trochlear dysplasia?

Pol J Radiol 2021 24;86:e232-e238. Epub 2021 Apr 24.

Department of Musculoskeletal Imaging, Royal Orthopaedic Hospital, Birmingham, UK.

Introduction: Trochlear dysplasia (TD) is a condition that is characterized by the presence of either a flat or convex trochlear, which impedes the stability of the patellofemoral joint (PFJ). The PFJ function is dependent on many different structures that surround the knee joint. The aim of this study was to analyse all the muscle components around the PFJ and identify whether gross muscle imbalance could contribute to the stability of the patella in TD. Read More

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Patients With Becker Muscular Dystrophy Have Severe Paraspinal Muscle Involvement.

Front Neurol 2021 21;12:613483. Epub 2021 May 21.

Copenhagen Neuromuscular Center, Department of Neurology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.

Paraspinal muscles are important for gross motor functions. Impairment of these muscles can lead to poor postural control and ambulation difficulty. Little knowledge exists about the involvement of paraspinal muscles in Becker muscular dystrophy. Read More

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Measuring the force perception in knee flexor/ extensor muscles in patients with anterior cruciate ligament injury and healthy subjects.

J Back Musculoskelet Rehabil 2021 Jun 4. Epub 2021 Jun 4.

Physiotherapy Department, Faculty of Rehabilitation Sciences, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Force perception as a contributor to the neuromuscular control of the knee joint may be altered after anterior cruciate ligament (ACL) injury.

Objective: This study aimed to compare the force perception accuracy in the knee joints of patients with ACL injury and healthy subjects.

Methods: Twenty-six patients with ACL injury and 26 healthy subjects participated in this case-control study. Read More

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Comparison between femoral block and PENG block in femoral neck fractures: A cohort study.

PLoS One 2021 4;16(6):e0252716. Epub 2021 Jun 4.

Department of Anesthesiology and Intensive Care, Hôpital Saint-Antoine, Assistance Publique-Hôpitaux de Paris, Paris, France.

Background: Regional analgesia is worth performing in the multimodal postoperative management of hip fracture (HF) because it reduces hospital morbidity and mortality. The aim of this study is to compare the efficacy and side effects of the recently described "Pericapsular Nerve Group (PENG) Block" with those of the femoral block, which is considered the standard of care for postoperative pain control after femoral neck fracture.

Materials And Methods: We conducted a comparative observational study at a university hospital (Saint Antoine Hospital, Sorbonne University, Paris, France), where the PENG block was introduced in August 2019. Read More

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Effects of Eccentric Single-Leg Decline Squat Training Performed With Different Execution Times on Maximal Strength and Muscle Contraction Properties of the Knee Extensor Muscles.

J Strength Cond Res 2021 Jun 2. Epub 2021 Jun 2.

Performance and Sport Rehabilitation Laboratory, Faculty of Sport Sciences, University of Castilla-La Mancha, Toledo, Spain; and Faculty of Humanities and Social Sciences, Comillas Pontifical University, Madrid, Spain.

Abstract: Abián-Vicén, J, Martínez, F, Jiménez, F, and Abián, P. Effects of eccentric single-leg decline squat training performed with different execution times on maximal strength and muscle contraction properties of the knee extensor muscles. J Strength Cond Res XX(X): 000-000, 2021-The eccentric phase of the single-leg decline squat (SLDSe) has been described as a method to maximally load the knee extensor and has been used as an easy and effective rehabilitation exercise for patellar tendinopathy. Read More

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Home-based pulmonary rehabilitation in people with bronchiectasis: a randomised controlled trial.

ERJ Open Res 2021 Apr 31;7(2). Epub 2021 May 31.

Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, Sao Paulo-SP, Brazil.

Aim: To investigate the short- and long-term effects of home-based pulmonary rehabilitation (HBPR) on functional capacity, quality of life, peripheral muscle strength, dyspnoea and daily physical activity in people with bronchiectasis.

Methods: Randomised controlled trial with 63 participants with bronchiectasis. The HBPR group performed three sessions per week for 8 weeks (aerobic exercise: step training for 20 min; resistance training: exercises for quadriceps, hamstrings, deltoids and biceps brachii using elastic bands). Read More

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Effect of Neuromuscular Exercises on Strength, Proprioceptive Receptors, and Balance in Females with Multiple Sclerosis.

Int J Prev Med 2021 19;12. Epub 2021 Jan 19.

Department of Sport Management, Faculty of Management, Farabi Campus, University of Tehran, Iran.

Background: Multiple sclerosis (MS) is the third most common cause of adult neurologic disabilities. The aim of this study was to determine the effect of 8 weeks of neuromuscular exercises on strength, proprioceptive receptors, and balance of women with MS.

Methods: In this randomized controlled trial study, 20 female volunteers with relapsing-remitting MS were randomly assigned into the experimental group ( = 10) and control group ( = 10). Read More

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January 2021

Muscle stimulation in advanced idiopathic pulmonary fibrosis: a randomised placebo-controlled feasibility study.

BMJ Open 2021 Jun 2;11(6):e048808. Epub 2021 Jun 2.

Harefield Respiratory Research Group, Royal Brompton and Harefield Clinical Group, Guy's and St Thomas' Hospitals NHS Trust, London, UK.

Objectives: To assess the acceptability of neuromuscular electrical stimulation (NMES) of the quadriceps muscles in people with idiopathic pulmonary fibrosis (IPF) and to identify whether a future definitive trial is feasible.

Design: A randomised, parallel, two-group, participant and assessor-blinded, placebo-controlled feasibility trial with embedded qualitative interviews.

Setting: Outpatient department, Royal Brompton and Harefield Hospitals. Read More

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Older adults are not more susceptible to acute muscle atrophy after immobilisation compared to younger adults: a systematic review.

Eur J Trauma Emerg Surg 2021 Jun 3. Epub 2021 Jun 3.

LIRRM, Academic T&O Unit, Clarendon Wing, D floor, Great George Street, Leeds, LS1 3EX, UK.

Purpose: To identify if older adults are more susceptible to acute muscle atrophy compared to younger adults.

Methods: All studies whose design involved a period of enforced immobilisation and a comparison between an older (> 40) and a younger cohort (< 40) were included. Outcome of interest was change in muscle mass, measured by radiological techniques or histological analysis of fibre size. Read More

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Extrapulmonary features of post-COVID-19 patients: muscle function, physical activity, mood, and sleep quality.

Ir J Med Sci 2021 Jun 2. Epub 2021 Jun 2.

Department of Cardiology, Faculty of Medicine, Dokuz Eylül University, Izmir, Turkey.

Background: Coronavirus disease 2019 (COVID-19) represents a wide range of clinical manifestations, even if mild disease severity. It has been known that pulmonary function is affected by COVID-19 during infection and mid-to-long term. However, there is inadequate evidence about extrapulmonary features in post-COVID-19 patients. Read More

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Regional variation of thigh muscle fat infiltration in patients with neuromuscular diseases compared to healthy controls.

Quant Imaging Med Surg 2021 Jun;11(6):2610-2621

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.

Background: Chemical shift encoding-based water-fat magnetic resonance imaging (CSE-MRI) measures a quantitative biomarker: the proton density fat fraction (PDFF). The aim was to assess regional and proximo-distal PDFF variations at the thigh in patients with myotonic dystrophy type 2 (DM2), limb-girdle muscular dystrophy type 2A (LGMD2A), and late-onset Pompe disease (LOPD) as compared to healthy controls.

Methods: Seven patients (n=2 DM2, n=2 LGMD2A, n=3 LOPD) and 20 controls were recruited. Read More

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Isotonic quadriceps endurance is better associated with daily physical activity than quadriceps strength and power in COPD: an international multicentre cross-sectional trial.

Sci Rep 2021 Jun 2;11(1):11557. Epub 2021 Jun 2.

Department of Community Medicine and Rehabilitation, Physiotherapy, Umeå University , Umeå, Sweden.

Knowledge about modifiable determinants of daily physical activity (PA) in patients with chronic obstructive pulmonary disease (COPD) is crucial to design effective PA interventions. The present study aimed to determine the contribution of quadriceps strength, power and endurance to daily PA in COPD. Additionally, for quadriceps endurance, we also aimed to determine to what extent the association varies according to the mode of movement (isotonic, isometric, or isokinetic). Read More

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Effect of taurine associated gold nanoparticles on oxidative stress in muscle of mice exposed to overuse model.

An Acad Bras Cienc 2021 31;93(2):e20191450. Epub 2021 May 31.

Laboratório de Bioquímica do Exercício em Saúde, Programa de Pós-Graduação em Ciências da Saúde, Faculdade de Medicina, Rua Imaculada Conceição, 155, Pontifícia Universidade Católica do Paraná, 80215-901 Curitiba, PR, Brazil.

Muscle overuse and its consequent muscle damage has no cure. Therefore, the present study aimed to investigate the regulatory role of tau-AuNPs on muscle recovery of muscle overuse model. The animals (Male Swiss mice) were randomly divided into four groups: Control (Ctr; n=6); tau-AuNPs (n=6); overuse (n=6); and overuse plus tau-AuNPs (n=6). Read More

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Effects of Cardiopulmonary Rehabilitation on the Muscle Function of Children with Congenital Heart Disease: A Prospective Cohort Study.

Int J Environ Res Public Health 2021 May 30;18(11). Epub 2021 May 30.

Department of Physiotherapy, Universidad Cardenal Herrera-CEU, CEU Universities, Alfara del Patriarca, 46113 Valencia, Spain.

Critical medical and surgical advances have led to a shift in the care and management of children with congenital heart disease (CHD). These patients present with muscle deconditioning, which negatively influences their response to exercise, functional capacities, and quality of life. This study evaluates the influence of a cardiopulmonary rehabilitation program (CPRP) on the function of peripheral musculature of children with CHD. Read More

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