J Mater Chem B 2020 12 28;8(45):10373-10383. Epub 2020 Oct 28.
State Key Laboratory of Oral Diseases & National Clinical Research Centre for Oral Disease, Sichuan University, No. 14, Section 3 of Renmin Road South, Chengdu, China. and Department of Cariology and Endodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, China.
Amelogenin and its various derived peptides play important roles in promoting biomimetic mineralization of enamel. Previously, an amelogenin-derived peptide named QP5 was proved to be able to repair demineralized enamel. The objective here was to interpret the mechanism of QP5 by elucidating the specific function of each domain for further sequence and efficacy improvement. Read More