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In-Office Needle Arthroscopy for the Treatment of Anterior Ankle Impingement Yields High Patient Satisfaction with High Rates of Return to Work and Sport.

Arthroscopy 2021 Sep 24. Epub 2021 Sep 24.

NYU Langone Health, Department of Orthopaedic Surgery, New York, NY. Electronic address:

Purpose: The purpose of the current study was to evaluate the clinical outcomes of in-office needle arthroscopy (IONA) for the treatment of anterior ankle impingement in the office setting, and also evaluate patient experience of the IONA procedure.

Methods: A prospectively collected database of 31 patients undergoing IONA for the treatment of anterior ankle impingement between January 2019 and January 2021 was retrospectively reviewed. Inclusion criteria for this study was: patients ≥ 18 years of age, clinical history, physical exam, radiographic imaging, and MRI consistent with anterior ankle impingement for which each patient underwent IONA and had a minimum of 12-month follow-up. Read More

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September 2021

Frailty and Its Correlates in Cognitively Intact Community-Dwelling Older Adults.

Dement Geriatr Cogn Disord 2021 Sep 16:1-7. Epub 2021 Sep 16.

Faculty of Nursing, Jordan University of Science and Technology, Irbid, Jordan.

Background: Frailty syndrome is characterized by a decline in physiological and psychological reserve and may be associated with poor health outcomes.

Objectives: The current study explored frailty and its correlates among cognitively intact community-dwelling older adults.

Methods: A secondary analysis of data collected from 109 community-dwelling older adults who are cognitively intact was conducted for the purpose of this study. Read More

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September 2021

Quality of Life of Urolithiasis Patients During the COVID-19 Pandemic: A Multi-Institutional Cross-Sectional Study.

J Endourol 2021 Sep 25. Epub 2021 Sep 25.

University of British Columbia, Urologic Sciences, Level 6, 2775 Laurel st., Level 6 - 2775 Laurel St, Vancouver, British Columbia, Canada, V5Z 1M9.

Purpose The COVID-19 pandemic is an unprecedented global event that has caused significant fear and anxiety across all populations. To date, there have been no studies on how major health crises have affected the stone-related quality-of-life (QOL) of urolithiasis patients. In this multi-institutional study, we investigated whether the fear of COVID-19 affects the QOL of urolithiasis patients during the COVID-19 pandemic using the Fear of COVID-19 Scale (FCV-19S) and the Wisconsin Stone Quality of Life (WISQOL) questionnaires. Read More

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September 2021

Assessment of quality of work life (QWL) among healthcare staff of intensive care unit (ICU) and emergency unit during COVID-19 outbreak using WHOQoL-BREF.

Saudi Pharm J 2021 Sep 20. Epub 2021 Sep 20.

Department of Clinical Pharmacy, College of Pharmacy, Umm Al Qura University, Makkah, Saudi Arabia.

Objective: The study aimed to document the quality of work life (QWL) among healthcare staff of intensive care unit (ICU) and emergency unit during COVID-19 outbreak using WHOQoL-BREF.

Methods: A multicenter cross-sectional study was conducted for two months (May - June 2020) among healthcare staff working in intensive care units (ICUs) and emergency units of the hospitals under National Guard Health Authority (NGHA) across five cities of Saudi Arabia. The study used the WHOQoL-BREF instrument to document the QWL through an electronic institutional survey. Read More

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September 2021

Effect of a multi-domain intervention on the quality of life in older adults with major neurocognitive disorder: A pilot study.

Rev Neurol (Paris) 2021 Sep 23. Epub 2021 Sep 23.

Ambulatory geriatric unit, Bretonneau hospital, Assistance publique-Hôpitaux de Paris, 23, rue Joseph-de-Maistre, 75018 Paris, France; Inserm UMR-S 1144, université de Paris, Paris, France.

Purpose: Major neurocognitive disorders (MND) have multiple negative consequences on patients' lives and on their caregivers' health. Occupational therapy and cognitive stimulation have failed to show any significant efficacy on quality of life (QoL), cognitive functioning and behavioural symptoms. Bretonneau Hospital's Day Care Unit offers personalized and structured multi-domain interventions to cognitively impaired older patients on a weekly basis, for a 3-month period. Read More

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September 2021

Effect of Light Therapy on Cancer-related Fatigue: A Systematic Review and Meta-Analysis.

J Pain Symptom Manage 2021 Sep 23. Epub 2021 Sep 23.

Department of Rehabilitation Sciences (Andy SK Cheng), The Hong Kong Polytechnic University, Hong Kong, China.

Context: Light therapy is a non-pharmacological therapy that is currently being studied in cancer-related symptoms and is certificated as a low-risk intervention by FDA. Cancer-related fatigue (CRF) is the most common symptom reported by cancer patients.

Objective: To examine the effectiveness of light therapy for CRF in cancer patients through a systematic review and meta-analysis. Read More

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September 2021

Effectiveness of self-care interventions for integrated morbidity management of skin neglected tropical diseases in Anambra State, Nigeria.

BMC Public Health 2021 Sep 25;21(1):1748. Epub 2021 Sep 25.

Department of Internal Medicine, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Ebonyi State, Nigeria.

Background: Lymphatic filariasis (LF), Buruli ulcer (BU) and leprosy are neglected tropical diseases (NTDs) of the skin co-endemic in some communities in Nigeria. Not enough is known about the effectiveness of integrated morbidity management and disability prevention in people with these conditions. An integrated self-care intervention was carried out for people with these skin NTDs in two endemic communities of Anambra state, Nigeria. Read More

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September 2021

Quality of Life of Infants, Toddlers and Preschoolers with Seborrhoeic, Allergic Contact and Atopic Dermatitis Before and During COVID-19 Pandemic.

Dermatol Ther (Heidelb) 2021 Sep 25. Epub 2021 Sep 25.

Kiev City Clinical Dermatovenereologic Hospital, Kiev, Ukraine.

Introduction: Different aspects of quality of life (QoL) of infants and children with atopic dermatitis (AD) are well studied but there is a lack of studies on seborrhoeic dermatitis (SD) and allergic contact dermatitis (ACD). The aim of this study was to compare the impact of SD, ACD and AD on young children. Parts of questionnaires were filled in during the COVID-19 pandemic and therefore we decided to check if the pandemic affected dermatology-specific health-related quality of life (HRQoL) in our patients. Read More

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September 2021

Patients' preferences for quality-of-life aspects in sarcopenia: a best-worst scaling study.

Eur Geriatr Med 2021 Sep 25. Epub 2021 Sep 25.

Division of Public Health, Epidemiology and Health Economics, World Health Organization Collaborating Centre for Public Health Aspects of Musculoskeletal Health and Ageing, University of Liège, Liège, Belgium.

Purpose: As information on patients' preferences regarding quality-of-life aspects in sarcopenia is lacking, this study aims to assess the relative importance of the 14 items of a QoL questionnaire designed for sarcopenia (the SF-SarQoL) using a best-worst scaling (BWS) survey.

Methods: Participants, aged 65 years or older and community dwelling, who previously participated in the SarcoPhAge study, received a BWS survey via the mail. An object case BWS was selected in which participants completed 12 choice tasks, picking the most and least important aspect from 4 out of 14 SF-SarQoL items for each task. Read More

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September 2021

Long-term quality of life among breast cancer survivors eligible for screening at diagnosis: a systematic review and meta-analysis.

Public Health 2021 Sep 21;199:65-76. Epub 2021 Sep 21.

Cancer Registry of Norway, Section of Cancer Screening, P.O. 5313, Majorstuen, Oslo, 0304, Norway; Department of Health and Care Sciences, UiT The Artic University of Norway, P.O. 6050, Tromsø, 9037, Norway. Electronic address:

Objectives: This study aimed to explore the long-term quality of life (QoL) among breast cancer survivors eligible for mammographic screening at diagnosis and compare that to QoL among women with no history of breast cancer.

Study Design: Systematic review and meta-analysis.

Methods: A systematic review of randomised controlled trials and observational studies published between January 2000 and July 2019 was performed. Read More

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September 2021

Quality of life in patients with locally advanced head and neck cancer treated with concurrent chemoradiation with cisplatin and nimotuzumab versus cisplatin alone - Additional data from a phase 3 trial.

Oral Oncol 2021 Sep 21;122:105517. Epub 2021 Sep 21.

Department of Medical Oncology, Tata Memorial Centre, Homi Bhabha National Institute (HBNI), Mumbai, India. Electronic address:

Introduction: The addition of Nimotuzumab to radical chemoradiation (CRT) improved outcomes in patients with locally advanced head and neck squamous cell carcinoma (LAHNSCC) undergoing radical CRT in a phase 3 randomized trial. The current study focuses on the quality of life (QoL) of patients in this trial.

Methods: In this phase III randomized trial, patients with newly diagnosed, nonmetastatic, stage III/IV LAHNSCC of the oral cavity, oropharynx, hypopharynx, or larynx were randomized to receive cisplatin 30 mg/m or cisplatin 30 mg/m with nimotuzumab once a week with curative radiotherapy. Read More

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September 2021

Randomized Prospective Trial Exploring the Impact of Structured Journaling in Patients With Sarcoma on the Management of Treatment-Related Adverse Events.

JCO Oncol Pract 2021 Sep 24:OP2100309. Epub 2021 Sep 24.

Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, OH.

Purpose: Treatment-related adverse events associated with systemic anticancer therapy (SACT) can deter patients with sarcoma from completing treatment. With self-monitoring, patients may be better empowered to self-advocate for improved symptom management. We hypothesized that by incorporating journaling, a structured form of self-monitoring, care team communication, and symptom management would improve. Read More

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September 2021

Does drainage or resection predict subsequent interventions and long-term quality of life in patients with Grade IV pancreatic injuries: A population-based analysis.

J Trauma Acute Care Surg 2021 Oct;91(4):708-715

From the Department of Surgery (C.G.B., A.W.K.), University of Calgary, Calgary, Alberta, Canada; Department of Surgery (W.L.B.), Scripps Clinic Medical Group, La Jolla, California; Department of Surgery (S.M.H.), University of British Columbia, Vancouver, BC, Canada; Department of Surgery (K.V., N.G.P.), Western University, London, Ontario, Canada; and Department of Surgery (M.K.), Cook County Hospital, Chicago, Illinois.

Background: Clinical equipoise remains significant for the treatment of Grade IV pancreatic injuries in stable patients (i.e., drainage vs. Read More

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October 2021

Health-Related Quality of Life of Patients with Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma Treated with Pembrolizumab in KEYNOTE-629.

Dermatol Ther (Heidelb) 2021 Sep 23. Epub 2021 Sep 23.

Aix-Marseille University, Marseille, France.

Introduction: Pembrolizumab provided durable responses and acceptable safety in recurrent or metastatic (R/M) cutaneous squamous cell carcinoma (cSCC) in the KEYNOTE-629 study. In this elderly, fragile population with disfiguring tumours, preservation of health-related quality of life (HRQoL) is critical. Here, we present pre-specified exploratory HRQoL analyses from the first interim analysis of KEYNOTE-629. Read More

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September 2021

Normobaric oxygen treatment for mild-to-moderate depression: a randomized, double-blind, proof-of-concept trial.

Sci Rep 2021 Sep 23;11(1):18911. Epub 2021 Sep 23.

Department of Nursing, Faculty of Health Sciences, School for Community Health Professions, Ben-Gurion University of the Negev, P.O.B 653, 8410501, Beer-Sheva, Israel.

Oxygen enriched air may increase oxygen pressure in brain tissue and have biochemical effects even in subjects without lung disease. Consistently, several studies demonstrated that normobaric oxygen treatment has clinical benefits in some neurological conditions. This study examined the efficacy of normobaric oxygen treatment in subjects with depression. Read More

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September 2021

Comparison of Postoperative Quality of Life and Pain with and without a Metal Rib Spreader in Patients Undergoing Lobectomy through Axillary Mini-Thoracotomy for Stage I Lung Cancer.

Ann Thorac Cardiovasc Surg 2021 Sep 23. Epub 2021 Sep 23.

Department of Thoracic Surgery, University of Tsukuba, Tsukuba, Ibaraki, Japan.

Purpose: To evaluate postoperative patient-reported quality of life (QOL) and pain with and without a metal rib spreader (MRS) in patients with stage I lung cancer who underwent lobectomy through axillary mini-thoracotomy (AMT).

Methods: This single-institution prospective observational study enrolled patients between January 2015 and April 2018. Their QOL and pain were evaluated using the EQ-5D and the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire 30 items (QLQ-C30). Read More

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September 2021

Health-related quality of life for early-stage cervical cancer survivors after primary radical surgery followed by radiotherapy versus radical surgery alone.

J Obstet Gynaecol 2021 Sep 23:1-8. Epub 2021 Sep 23.

Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

This study compared the quality of life (QoL) of 265 stage IA2-IIA cervical cancer patients treated with radical surgery alone (group 1: 137 patients) versus those who underwent primary radical surgery followed by radiotherapy (group 2: 128 patients) and identified clinical characteristics that predict the poor quality of life. All participants completed quality of life questionnaires: EORTC QLQ-C30 and CMU cervical cancer QoL. For the EORTC QLQ-C30, the study groups were comparable regarding global health status/QoL scale and summary scores. Read More

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September 2021

Effect of an ashwagandha (Withania Somnifera) root extract on climacteric symptoms in women during perimenopause: A randomized, double-blind, placebo-controlled study.

J Obstet Gynaecol Res 2021 Sep 22. Epub 2021 Sep 22.

Department of Pharmacology, D Y Patil University School of Medicine, Navi Mumbai, India.

Background: Perimenopause is the period during which many physiological changes mark the transition into the final menstrual period of a woman and these changes are associated with climacteric symptoms.

Objectives: This study aimed to assess the efficacy and tolerability of an Ashwagandha root extract on the climacteric symptoms, quality of life (QoL), and hormonal parameters in perimenopausal women.

Materials And Methods: In this 8-week, randomized, double-blind, placebo-controlled study, 100 women with climacteric symptoms were randomly allocated to take either a placebo or 300 mg of an Ashwagandha root extract twice daily. Read More

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September 2021

Effects of Cataract Surgery on Vision-Related Quality of Life in Patients with Retinitis Pigmentosa and the Predictive Factors of Quality of Life Improvement.

Biomed Res Int 2021 13;2021:3846867. Epub 2021 Sep 13.

Department of Ophthalmology and Visual Science, Chiba University Graduate School of Medicine, Chiba, Japan.

Purpose: To determine the effects of cataract surgery and preoperative factors on the vision-related quality of life (QOL) in patients with retinitis pigmentosa (RP).

Materials And Methods: This was a prospective, interventional study of 54 patients diagnosed with RP. The 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) was used to determine the QOL before and after the cataract surgery. Read More

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September 2021

The impact of radiotherapy on the quality of life in patients with early-stage clinical head and neck cancer.

Otolaryngol Pol 2021 May;75(5):1-8

Department of Otolaryngology and Laryngological Oncology, Medical University of Karol Marcinkowski in Poznan, Poland.

Radiotherapy (RT) for patients with head and neck squamous cell carcinoma (HNSCC) affects vital functions related to the irradiation volume of the head and neck region and, in addition, has a negative impact on social functioning, thereby significantly impairing patients' quality of life (QoL). The aim of this study was to assess changes in the quality of life in patients with head and neck cancer treated with curative RT at 12 months after completion of RT. The aim of this study was to assess the differences between the baseline QoL of patients with early clinical stage HNSCC and at 12 months after curative/radical RT. Read More

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Clinical features and related factors of freezing of gait in patients with Parkinson's disease.

Brain Behav 2021 Sep 22:e2359. Epub 2021 Sep 22.

Department of Neurology, General Hospital of Ningxia Medical University, Ningxia Key Laboratory of Cerebrocranial Diseases, Incubation Base of National Key Laboratory, Yinchuan, China.

Background: Freezing of gait (FOG) is a disabling paroxysmal gait disorder that prevents starting or resuming walking, which seriously negatively affects patients' quality of life (QOL). The diagnosis and treatment of FOG remain a huge medical challenge. The purpose of this study was to explore the clinical characteristics and related factors of FOG in patients with Parkinson's disease (PD). Read More

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September 2021

A Longitudinal Examination of Quality of Life of Older Adults with Complicated Grief Receiving Accelerated Resolution Therapy.

J Palliat Med 2021 Sep 22. Epub 2021 Sep 22.

Csomay Center for Gerontological Excellence, University of Iowa College of Nursing, Iowa City, Iowa, USA.

To examine the effect of Accelerated Resolution Therapy (ART) on the quality of life (QOL) of older adults with complicated grief (CG) over time. Subanalysis of a randomized controlled trial. Older adult, former caregivers were recruited from a large hospice in the southeastern United States to be treated with ART for CG. Read More

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September 2021

Survival analysis of a prospective multicenter observational study on surgical palliation among patients with malignant bowel obstruction caused by peritoneal dissemination of gastric cancer.

Gastric Cancer 2021 Sep 22. Epub 2021 Sep 22.

Department of Surgical Oncology, Gifu University Graduate School of Medicine, Gifu, Japan.

Background: Our previous report showed that surgical palliation maintained quality of life (QOL), improved solid food intake, and had an acceptable surgical safety among patients with malignant bowel obstruction (MBO) caused by advanced gastric cancer. This study performed a survival analysis stratified by the patients' QOL to elucidate its impact on survival.

Methods: Patients who underwent resection or bypass of the small intestine/colon or ileostomy/colostomy for bowel obstruction caused by peritoneal dissemination of gastric cancer were included. Read More

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September 2021

Longitudinal Comparison of Stability and Sensitivity in Quality of Life Scores Among Nursing Home Residents With and Without Diagnoses of Alzheimer's Disease and Related Dementias.

Innov Aging 2021 21;5(3):igab024. Epub 2021 Jul 21.

Division of Health Policy and Management, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA.

Background And Objectives: Prevalence of nursing home residents with Alzheimer's disease and related dementias (ADRD) has increased along with a growing consensus that person-centered ADRD care in nursing homes should maximize quality of life (QoL). However, concerns about whether residents with ADRD can make appropriate QoL judgments persist. This study assesses the stability and sensitivity of a self-reported, multidomain well-being QoL measure for nursing home residents with and without ADRD. Read More

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Quality of Life Assessment and Pain Severity in Breast Cancer Patients Prior to Palliative Oncology Treatment in Indonesia: A Cross-Sectional Study.

Patient Prefer Adherence 2021 14;15:2017-2026. Epub 2021 Sep 14.

Institute for Medical Epidemiology, Biometrics and Informatics (IMEBI), Interdisciplinary Center for Health Sciences, Medical School of the Martin-Luther-University Halle-Wittenberg, Halle (Saale), Germany.

Purpose: Studies assessing quality of life (QOL) in palliative care settings are still scarce. We assessed the QOL score and pain severity in advanced breast cancer patients at the National Cancer Hospital in Indonesia and associations between QOL domains with QOL and pain scores.

Materials And Methods: A total of 160 patients who met the study inclusion criteria (female, >18 years old, diagnosed with stage III or IV breast cancer) answered the European Organization for Research and Treatment of Cancer QOL questionnaire (EORTC QLQ-C15-PAL) and the visual analogue scale (VAS) tool for pain severity, prior to palliative oncology treatment. Read More

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September 2021

Impact of using spirometry on clinical decision making and quality of life in children: protocol for a single centre randomised controlled trial.

BMJ Open 2021 Sep 21;11(9):e050974. Epub 2021 Sep 21.

Child Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia.

Introduction: Although spirometry has been available for decades, it is underused in paediatric practice, other than in specialist clinics. This is unsurprising as there is limited evidence on the benefit of routine spirometry in improving clinical decision making and/or outcomes for children. We hypothesised that using spirometry for children being evaluated for respiratory diseases impacts on clinical decision making and/or improves patient-related outcome measures (PROMs) and/or quality of life (QoL), compared with not using spirometry. Read More

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September 2021

Long-term functional and psychosocial outcome in adolescents and young adults treated for lower urinary tract dysfunction in childhood.

J Pediatr Urol 2021 Sep 3. Epub 2021 Sep 3.

Department of Medical Psychology, Radboud University Medical Center, Amalia Children's Hospital, Nijmegen, the Netherlands. Electronic address:

Background: Lower urinary tract dysfunction (LUTD) in childhood might affect lower urinary tract function and psychological wellbeing later in life. This study presents long-term functional outcome, psychological outcome and quality of life (QOL) of adolescents and young adults treated for childhood LUTD compared to healthy age-matched controls. In addition, association with past treatment outcomes is evaluated. Read More

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September 2021

Colloid cysts: Neuropsychological outcome, quality of life and long-term control after endoscopic gross total resection.

Clin Neurol Neurosurg 2021 Sep 16;209:106951. Epub 2021 Sep 16.

Department of Neurosurgery, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.

Background: Endoscopy is increasingly being adopted for removing colloid cysts. However, the neuropsychological outcome and quality of life (QOL) have not been studied in detail. This study is to evaluate the efficacy of endoscopic excision on cognitive measures and QOL. Read More

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September 2021

Facial emotion recognition and its association with quality of life and socio-occupational functioning in patients with bipolar disorder and their first-degree relatives.

Asian J Psychiatr 2021 Sep 11;65:102843. Epub 2021 Sep 11.

Wellcome Trust / DBT Alliance Intermediate Fellow, Associate Consultant Psychiatry, KEM Hospital Research Centre, 489, Rastapeth, Sardar Moodliar Road, Pune, Maharashtra 411011, India. Electronic address:

Introduction: Facial emotion recognition deficits (FERD) are common even in the remitted phase of bipolar disorder (BD). Research regarding FERD in first-degree relatives is inconclusive. This study aimed to assess the facial emotion recognition in remitted patients of bipolar disorder and first-degree relatives(FDR) in comparison with healthy controls. Read More

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September 2021

The estimation of a preference-based single index for the IBS-QoL by mapping to the EQ-5D-5L in patients with irritable bowel syndrome.

Qual Life Res 2021 Sep 21. Epub 2021 Sep 21.

Department of Clinical Epidemiology and Medical Technology Assessment, CAPHRI Care and Public Health Research Institute, Maastricht University Medical Center, Maastricht, The Netherlands.

Purpose: The Irritable Bowel Syndrome Quality of Life (IBS-QoL) questionnaire is a commonly used and validated IBS-specific QoL instrument. However, this questionnaire is in contrast to the EQ-5D-5L, not preference-based and as such does not allow calculation of QALYs. The objective of this study was to describe the convergent- and known-group validity of both questionnaires and to develop a mapping algorithm from EQ-5D-5L which enable IBS-QoL scores to be transformed into utility scores for use in economic evaluations. Read More

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September 2021