Graefes Arch Clin Exp Ophthalmol 2019 Nov 16;257(11):2401-2427. Epub 2019 Sep 16.
Centre de Recherches des Cordeliers, UMR_S INSERM 1138, Equipe 17, Université Paris Descartes, 15 rue de l'école de médecine, 75006, Paris, France.
Purpose: This study was conducted in order to study Sostdc1 expression in rat and human developing and adult eyes.
Methods: Using the yeast signal sequence trap screening method, we identified the Sostdc1 cDNA encoding a protein secreted by the adult rat retinal pigment epithelium. We determined by in situ hybridization, RT-PCR, immunohistochemistry, and western blot analysis Sostdc1 gene and protein expression in developing and postnatal rat ocular tissue sections. Read More