280,173 results match your criteria psychiatric patients


Anxiety and Depression Impact on Inhospital Complications and Outcomes After Total Knee and Hip Arthroplasty: A Propensity Score-Weighted Retrospective Analysis.

J Am Acad Orthop Surg 2020 Nov 18. Epub 2020 Nov 18.

From the Department of Orthopeadic Surgery and Sports Medicine, Detroit Medical Center, Detorit, MI (Zalikha and El-Othmani), and the Department of Biomedical Sciences, Oakland University William Beaumont School of Medicine, Auburn Hills, MI (Karabon and Hajj Hussein).

Introduction: The purpose of this study was to assess the impact of anxiety and depression on immediate inhospital outcomes and complications after total joint arthroplasty of the hip (total hip arthroplasty [THA]) and knee (total knee arthroplasty [TKA]) using a large national registry.

Methods: Data from the National Inpatient Sample was used to identify all patients undergoing TKA and THA between 2006 and 2015. Patients were divided in four groups based on a concomitant diagnosis of depression, anxiety, depression plus anxiety, and neither depression nor anxiety (control group). Read More

View Article and Full-Text PDF
November 2020

Multivariate pattern analysis links drug use severity to distributed cortical hypoactivity during emotional inhibitory control in opioid use disorder.

Neuroimage Clin 2021 Aug 29;32:102806. Epub 2021 Aug 29.

Center for Studies of Addiction, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, 3535 Market St Ste 500, Philadelphia, PA 19104, USA.

Opioid use disorder (OUD) is characterized by emotional and cognitive impairements that are associated with poor treatment outcomes. The present study investigated the neural mechanism underlying emotion evaluation and inhibitory control using an affective go/no-go (AGN) task and its association with drug use severity and craving in patients with OUD. Twenty-six recently detoxified patients with OUD underwent functional magnetic resonance imaging (fMRI) while performing the AGN task that required response to frequently presented appetitive stimuli ("go") and inhibition of response to infrequently presented aversive stimuli ("no-go"). Read More

View Article and Full-Text PDF

A retrospective records study of patterns in mental health and criminal justice service use by people found not criminally responsible on account of mental disorder.

Crim Behav Ment Health 2021 Sep 15. Epub 2021 Sep 15.

Department of Psychiatry, University of British Columbia, Vancouver, British Columbia, Canada.

Background: While the presence or absence of previous healthcare and criminal justice system (CJS) contacts in the histories of mentally ill offenders has been well-studied, the frequency of these contacts and when they occur in the period leading up to an index criminal event has received less research attention.

Aims: To explore patterns of healthcare and CJS use in the year prior to a criminal act leading to a Not Criminally Responsible on Account of Mental Disorder (NCRMD) finding in Canada.

Methods: In this 3-year retrospective records study, the case files of all patients newly admitted to the British Columbia forensic psychiatric system after a finding of NCRMD between 1st July 2012 and 31st July 2015 were reviewed. Read More

View Article and Full-Text PDF
September 2021

Understanding factors in burn patient follow-up.

J Burn Care Res 2021 Sep 15. Epub 2021 Sep 15.

Department of Surgery, Division of Burn Surgery, University of California, Davis, Sacramento, CA,. Stockton Blvd, Sacramento, CA.

Follow-up rates (FUR) are concerningly low among burn-injured patients. This study investigates the factors associated with low FUR and missed appointments (MA). We hypothesize that patients who are homeless, use illicit substances, and have psychiatric comorbidities will have lower rates of follow-up (FU) and more MAs. Read More

View Article and Full-Text PDF
September 2021

Cerebello-Thalamo-Cortical Hyperconnectivity Classifies Patients and Predicts Long-Term Treatment Outcome in First-Episode Schizophrenia.

Schizophr Bull 2021 Sep 15. Epub 2021 Sep 15.

Huaxi MR Research Center, Department of Radiology, West China Hospital of Sichuan University, Chengdu, China.

It has previously been shown that cerebello-thalamo-cortical (CTC) hyperconnectivity is likely a state-independent neural signature for psychosis. However, the potential clinical utility of this change has not yet been evaluated. Here, using fMRI and clinical data acquired from 214 untreated first-episode patients with schizophrenia (62 of whom were clinically followed-up at least once at the 12th and 24th months after treatment initiation) and 179 healthy controls, we investigated whether CTC hyperconnectivity would serve as an individualized biomarker for diagnostic classification and prediction of long-term treatment outcome. Read More

View Article and Full-Text PDF
September 2021

Identifying risk factors that increase analgesic requirements at discharge among patients with burn injuries.

J Burn Care Res 2021 Sep 15. Epub 2021 Sep 15.

Division of Plastic and Reconstructive Surgery, University of Toronto, Toronto, Ontario, Canada.

Patients with burn injuries require large doses of opioids and gabapentinoids to achieve pain control and are often discharged from hospital with similar amounts. This study aimed to identify patient risk factors that increase analgesic requirements among patients with burn injuries and to determine the relationship between opioid and gabapentinoid use. Patient charts from July 1, 2015 - 2018 were reviewed retrospectively to determine analgesic requirements 24 hours before discharge. Read More

View Article and Full-Text PDF
September 2021

Attitudes of legal guardians and legally supervised persons with and without previous research experience towards participation in research projects: A quantitative cross-sectional study.

PLoS One 2021 15;16(9):e0256689. Epub 2021 Sep 15.

Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.

Background: Vulnerable groups, e.g. persons with mental illness, neurological deficits or dementia, are often excluded as participants from research projects because obtaining informed consent can be difficult and tedious. Read More

View Article and Full-Text PDF
September 2021

Impact on the Risk and Severity of Childhood Onset Schizophrenia of Schizophrenia Risk Genetic Variants at the DRD2 and ZNF804A Loci.

Child Psychiatry Hum Dev 2021 Sep 15. Epub 2021 Sep 15.

Department of Clinical Genetics, Mental Health Research Center, Moscow, Russia.

The study explored whether schizophrenia risk alleles of the DRD2 rs2514218 and ZNF804A rs1344706 polymorphisms also influenced the risk and severity of childhood-onset schizophrenia (COS) and differentiated it from autism spectrum disorders (ASD). We compared 75 children with COS to 75 children with ASD, 150 patients with adult-onset schizophrenia and 150 healthy individuals. Frequency of the DRD2 T-allele, assumed to be protective against schizophrenia overall, was higher in COS compared to adult-onset schizophrenia and healthy controls. Read More

View Article and Full-Text PDF
September 2021

Perceived quality of life (QOLIE-31-P), depression (NDDI-E), anxiety (GAD-7), and insomnia in patients with epilepsy attended at a refractory epilepsy unit in real-life clinical practice.

Neurol Sci 2021 Sep 15. Epub 2021 Sep 15.

Epilepsy Unit, Neurology Department, Hospital Universitario de La Princesa & Instituto de Investigación Sanitaria La Princesa, Madrid, Spain.

Objectives: This study aims to evaluate the relationship between psychiatric comorbidity (anxiety and depression), somnolence, and quality of life, using validated scales in patients with epilepsy in real-life clinical practice and clinical and demographic variables.

Methods: A cross-sectional observational study was conducted. Self-administered scales of anxiety disorders (GAD-7), depression (NDDI-E), somnolence (Epworth Sleepiness Scale (ESS)), and quality of life (QOLIE-31-P) in patients with epilepsy treated in the refractory epilepsy unit of a tertiary hospital were employed. Read More

View Article and Full-Text PDF
September 2021

Interplay between spirituality and religiosity on the physical and mental well-being of cancer survivors.

Support Care Cancer 2021 Sep 15. Epub 2021 Sep 15.

Department of Internal Medicine, Section of Hematology-Oncology, University of Nebraska Medical Center, Omaha, NE, USA.

Purpose: This study explored the relationship of spirituality and religiosity as it affects the physical and mental quality of life (pQOL, mQOL) of cancer survivors.

Methods: This is a prospective observational study that included adults ≥ 19 years who received treatment for various types of cancer. Patients' QOL was obtained at baseline, 6, and 12 months. Read More

View Article and Full-Text PDF
September 2021

Post-traumatic stress disorder in refugee minors in an outpatient care center: prevalence and associated factors.

Eur Child Adolesc Psychiatry 2021 Sep 15. Epub 2021 Sep 15.

Department of Child and Adolescent Psychiatry, Psychotherapy, and Psychosomatics, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany.

Due to their likelihood for experiencing a number of traumatic events, refugee minors have an increased risk of developing post-traumatic stress disorder (PTSD). However, the prevalence of PTSD in refugee children varies widely between studies, and it remains somewhat unclear what factors increase children's risk of PTSD. This study aimed to assess the prevalence of PTSD in a clinical outpatient sample of refugee minors, and to evaluate the association of different risk factors with a PTSD diagnosis. Read More

View Article and Full-Text PDF
September 2021

Analysis of State Cannabis Laws and Dispensary Staff Recommendations to Adults Purchasing Medical Cannabis.

JAMA Netw Open 2021 Sep 1;4(9):e2124511. Epub 2021 Sep 1.

Center to Improve Veteran Involvement in Care, VA Portland Health Care System, Portland, Oregon.

Importance: Over the last decade, cannabis has become more accessible through the proliferation of dispensaries in states that have legalized its use. Most patients using cannabis for medical purposes report getting advice from dispensaries, yet there has been little exploration of frontline dispensary staff practices.

Objective: To describe the practices of frontline dispensary workers who interact with customers purchasing cannabis for medical purposes and assess whether dispensary practices are associated with medicalization of state cannabis laws (degree to which they resemble regulation of prescription or over-the-counter drugs) and statewide adult use. Read More

View Article and Full-Text PDF
September 2021

Perturbations in Gut Microbiota Composition in Psychiatric Disorders: A Review and Meta-analysis.

JAMA Psychiatry 2021 Sep 15. Epub 2021 Sep 15.

Centre for Affective Disorders, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, United Kingdom.

Importance: Evidence of gut microbiota perturbations has accumulated for multiple psychiatric disorders, with microbiota signatures proposed as potential biomarkers. However, no attempts have been made to evaluate the specificity of these across the range of psychiatric conditions.

Objective: To conduct an umbrella and updated meta-analysis of gut microbiota alterations in general adult psychiatric populations and perform a within- and between-diagnostic comparison. Read More

View Article and Full-Text PDF
September 2021

The interplay between stress and fullness in patients with functional dyspepsia and healthy controls: an exploratory experience sampling method study.

Psychosom Med 2021 Sep 14. Epub 2021 Sep 14.

Division of Gastroenterology-Hepatology, Department of Internal Medicine, School of Nutrition and Translational Research in Metabolism (NUTRIM), Maastricht University Medical Centre+, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands Food Innovation and Health, Centre for Healthy Eating and Food Innovation, Maastricht University, 5911 AA Venlo, The Netherlands Department of Psychiatry and Psychology, Maastricht University Medical Centre, Maastricht, The Netherlands.

Objective: Fullness is a cardinal symptom in functional dyspepsia (FD). The use of real-time symptom assessment might provide more insight in factors, such as daily stress, that can influence fullness. Therefore, this study aimed to use the Experience Sampling Method (ESM, a real-time, repeated measurement method making use of repeated questionnaires available at random moments for a limited amount of time) to assess the association between stress and fullness in patients with FD and healthy controls (HC). Read More

View Article and Full-Text PDF
September 2021

Shift in Social Media App Usage During COVID-19 Lockdown and Clinical Anxiety Symptoms: Machine Learning-Based Ecological Momentary Assessment Study.

JMIR Ment Health 2021 Sep 15;8(9):e30833. Epub 2021 Sep 15.

Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

Background: Anxiety symptoms during public health crises are associated with adverse psychiatric outcomes and impaired health decision-making. The interaction between real-time social media use patterns and clinical anxiety during infectious disease outbreaks is underexplored.

Objective: We aimed to evaluate the usage pattern of 2 types of social media apps (communication and social networking) among patients in outpatient psychiatric treatment during the COVID-19 surge and lockdown in Madrid, Spain and their short-term anxiety symptoms (7-item General Anxiety Disorder scale) at clinical follow-up. Read More

View Article and Full-Text PDF
September 2021

The costs of bipolar disorder in the United Kingdom.

Brain Behav 2021 Sep 15:e2351. Epub 2021 Sep 15.

Department of Psychiatry, University of Oxford and Oxford Health NHS Trust, Oxford, United Kingdom.

Objectives: To estimate the individual cost and population-level economic burden of Bipolar Disorder (BD), and explore the impact of clinical and sociodemographic factors on costs in the United Kingdom.

Methods: Annual UK health care, social care and societal cost data were collected from a prospective cohort of 91 BD patients using digital monitoring of symptoms. Costs (in £) were calculated for the year of resource use collection (2010-2011) and main results inflated to year 2018-2019. Read More

View Article and Full-Text PDF
September 2021

Emotional dysfunction in avoidant personality disorder and borderline personality disorder: A cross-sectional comparative study.

Scand J Psychol 2021 Sep 15. Epub 2021 Sep 15.

Psychiatry, Aalborg University Hospital, Aalborg, Denmark.

According to the literature, avoidant personality disorder (APD) is often overlooked in research on personality disorders. In the present study, patients with APD were compared to patients with borderline personality disorder (BPD) with respect to emotional dysfunction. Emotional dysfunction was operationalized through the Affect Integration Inventory. Read More

View Article and Full-Text PDF
September 2021

[The therapeutic alliance as predictor in the treatment of young people].

Tijdschr Psychiatr 2021 ;63(7):535-542

Background: The quality of the therapeutic alliance is an important factor in the treatment of both adult and adolescent patients in psychiatry. Little is known about the importance of the therapeutic alliance among youths who seek help for their substance abuse problems in addiction treatment.

Aim: We investigated the importance of first treatment session therapeutic alliance for outcome in youth mental health and addiction treatment, considering both the youths' and therapists' perspective. Read More

View Article and Full-Text PDF
September 2021

[Pregnancy and psychiatry: a description of patients and the conducted interventions seen at a POP-clinic].

Tijdschr Psychiatr 2021 ;63(7):526-534

Background: Pregnancy and the postpartum period is a vulnerable phase in life for women and can influence the development or course of a psychiatric disorder. These patients can receive extra guidance during this period by the POP-collaboration (Psychiatry, Obstetrics and Pediatrics) in many hospitals.

Aim: To describe the characteristics of patients who received psychiatric consultation by the POP-collaboration at the LUMC and the interventions that were conducted. Read More

View Article and Full-Text PDF
September 2021

[Neuropsychiatric recovery after COVID-19 - an observational cohort-study].

Tijdschr Psychiatr 2021 ;63(7):514-521

Background: Since the end of 2019, COVID-19 and its consequences are present everywhere. Dutch professionals are concerned about the mental consequences, and in particular that during and after hospitalization little attention is paid to psychological problems.

Aim: To monitor the short-term course and severity of (neuro)psychiatric symptoms after hospitalization for COVID-19. Read More

View Article and Full-Text PDF
September 2021

[Neuropsychiatric manifestations of COVID-19 in intensive care unit patients].

Tijdschr Psychiatr 2021 ;63(7):509-513

It has become clear that COVID-19 can lead to neuropsychiatric complications. In this article, three cases are discussed that illustrate how neuropsychiatric complications can manifest within the COVID-19 disease course. Patients are at risk to develop a severe, hyperactive delirium, which is often accompanied by anxiety and sometimes neurological symptoms. Read More

View Article and Full-Text PDF
September 2021

[COVID-19 and severe mental illness, especially in clozapine use].

Tijdschr Psychiatr 2021 ;63(7):499-508

Background: The Clozapine Plus Working Group is frequently consulted for advice on measures in case of infection with SARSCoV-2 and on vaccination against COVID-19 in patients receiving clozapine.

AIM: Inform about risks of infection with SARS-CoV-2 in patients with severe mental illness (SMI), patients with schizophrenia spectrum disorders (SSD), and patients treated with clozapine. Advise on monitoring of clozapine plasma levels and white blood cell count and differential in COVID-19 and after vaccination, as well as measures to be taken. Read More

View Article and Full-Text PDF
September 2021

Factors associated with fluoxetine and norfluoxetine plasma concentrations and clinical response in Mexican patients with mental disorders.

Pharmacol Res Perspect 2021 Oct;9(5):e00864

Department of Pharmacy, Faculty of Chemical Sciences, Autonomous University of San Luis Potosí, San Luis Potosí, México.

Over the last few years, fluoxetine has been one of the most prescribed medications for the treatment of diverse psychiatric conditions in Mexico. Fluoxetine therapeutic effect is consequence of the joint action of the parent drug and its active metabolite, norfluoxetine. However, the clinical efficacy of fluoxetine, can be affected due to diverse factors, such as drug-drug interactions and the large interindividual variability in the pharmacokinetics of this drug. Read More

View Article and Full-Text PDF
October 2021

Provisional posttraumatic stress disorder is associated with greater severity of eating disorder and comorbid symptoms in adolescents treated in residential care.

Eur Eat Disord Rev 2021 Sep 14. Epub 2021 Sep 14.

Monte Nido and Affiliates, Miami, Florida, USA.

Objective: Past traumatic events, subsequent posttraumatic stress disorder (PTSD) and related psychiatric comorbidities are commonly associated with eating disorders (EDs) in adults but remain understudied in adolescents.

Methods: Adolescent participants (mean [SD] age = 15.1 ± 1. Read More

View Article and Full-Text PDF
September 2021

Is non-completion of treatment related to security need?

Crim Behav Ment Health 2021 Sep 14. Epub 2021 Sep 14.

National Forensic Mental Health Service, Central Mental Hospital, Dublin, Ireland.

Background: Treatment completion difficulties are common in forensic mental health settings and may have a profound impact on recidivism rates.

Aims: To test for associations between measures of risk and of security needs on the one hand and treatment non-completion on the other among male offender-patients in one medium security hospital.

Methods: We conducted a retrospective file study in a Flemish medium security hospital. Read More

View Article and Full-Text PDF
September 2021

Electroconvulsive Therapy and Psychiatric Readmission in Major Depressive Disorder - A Population-Based Register Study.

Acta Psychiatr Scand 2021 Sep 15. Epub 2021 Sep 15.

Faculty of Medicine and Health, Örebro University, Örebro, Sweden.

Objective: The primary aim was to determine whether electroconvulsive therapy (ECT) is associated with reduced risk of psychiatric readmission in major depressive disorder (MDD).

Methods: This study was based on data from multiple Swedish population-based registries. All adult patients admitted to any Swedish hospital for moderate-to-severe MDD between 2012-2018 were included. Read More

View Article and Full-Text PDF
September 2021

Hepatitis C prevalences in the psychiatric setting: Cost-effectiveness of scaling-up screening and direct-acting antiviral therapy.

JHEP Rep 2021 Jun 18;3(3):100279. Epub 2021 Mar 18.

Division of Clinical Pharmacology and Toxicology, Department of Anaesthesiology, Clinical Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland.

Background & Aims: Patients hospitalised because of mental illness often have risk factors for contracting HCV. Scaling-up HCV screening for all psychiatric inpatients as a case-detection strategy for viral elimination is underexplored. This study aimed to evaluate the cost-effectiveness of scaling-up HCV screening and treatment for psychiatry hospital admissions in Switzerland the current standard-of-care risk-based approach, where only those with a history of substance misuse disorder are offered testing. Read More

View Article and Full-Text PDF

Encephalopathy-causing mutations in Gβ () alter regulation of neuronal GIRK channels.

iScience 2021 Sep 21;24(9):103018. Epub 2021 Aug 21.

Department of Physiology and Pharmacology, School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.

Mutations in the gene, encoding the Gβ subunit of heterotrimeric G proteins, cause Encephalopathy. Patients experience seizures, pointing to abnormal activity of ion channels or neurotransmitter receptors. We studied three Gβ mutations (K78R, I80N and I80T) using computational and functional approaches. Read More

View Article and Full-Text PDF
September 2021