1,033 results match your criteria psychiatric nonpsychiatric

Commentary: Psychiatric Presentations of Nonpsychiatric Illness or Treatment.

Amir Garakani

J Psychiatr Pract 2021 Sep 16;27(5):404-405. Epub 2021 Sep 16.

GARAKANI: Department of Psychiatry and Behavioral Health, Greenwich Hospital, Greenwich, CT; Department of Psychiatry, Yale University School of Medicine, New Haven, CT.

Patients presenting with psychiatric symptoms, even in cases where there is no clear psychiatric history, are often labeled as having "psychogenic" symptoms or a psychosomatic reaction, and a tendency does exist to mislabel and/or misdiagnose certain patients in medical settings. The 3 cases presented in this issue of the Journal provide examples of patients presenting with psychotic or manic symptoms in the context of an underlying nonpsychiatric medical disorder. Kim and colleagues describe the case of a 65-year-old man with no psychiatric history who presented with acute visual hallucinations 1 day after starting omeprazole for gastroesophageal reflux. Read More

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September 2021

The Sensory Gating Inventory-Brief.

Schizophr Bull Open 2021 Jan 1;2(1):sgab019. Epub 2021 Jun 1.

Psychological & Brain Sciences, Indiana University, Bloomington, IN, USA.

The Sensory Gating Inventory (SGI) is a 36-item measure used to assess an individual's subjective ability to modulate, filter, over-include, discriminate, attend to, and tolerate sensory stimuli. Due to its theoretical and empirical link with sensory processing deficits, this measure has been used extensively in studies of psychosis and other psychopathology. The current work fills a need within the field for a briefer measure of sensory gating aberrations that maintains the original measure's utility. Read More

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January 2021

Prevalence and Functional Consequences of Social Anxiety in Individuals at Clinical High-Risk for Psychosis: Perspective From a Community Sample Comparison.

Schizophr Bull Open 2021 Jan 26;2(1):sgab025. Epub 2021 Jun 26.

Department of Psychology, Northwestern University, Evanston, IL, USA.

Background: Social anxiety disorder (SAD) commonly occurs among individuals at clinical high-risk (CHR) for psychosis. Extant research has yet to examine the prevalence and clinical/functional correlates of SAD in this population compared to a community control (CC) sample. This comparison may improve the generalizability that traditional nonpsychiatric control samples cannot provide. Read More

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January 2021

Antipsychotics Use Is Associated With Greater Adherence to Cardiometabolic Medications in Patients With Schizophrenia: Results From a Nationwide, Within-subject Design Study.

Schizophr Bull 2021 Jul 21. Epub 2021 Jul 21.

Niuvanniemi Hospital, Kuopio,Finland.

Background: People with schizophrenia/schizoaffective disorder (schizophrenia) die early, largely due to cardiovascular-related mortality. Antipsychotics are associated with lower mortality. We aimed to explore whether antipsychotic use can reduce discontinuation of medications for cardiovascular risk factors and diseases ("cardiometacolic drugs"), using a within-study design controlling for subject-related factors. Read More

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Bipolar disorder and Susac syndrome: a case report.

Int Clin Psychopharmacol 2021 Jul 15. Epub 2021 Jul 15.

Bipolar and Depressive Disorders Unit, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM Autoimmune Diseases Department, Institut d'Investigacions August Pi i Sunyer, Universitat de Barcelona, Hospital Clinic, Barcelona, Catalonia, Spain.

Susac-syndrome is a rare autoimmune disease that manifests with mood alterations in up to 15% of cases and is usually treated with corticosteroids. We present the case of a 41-year-old woman with a first manic episode and history of Susac-syndrome, secondary Cushing's syndrome after receiving high doses of corticosteroids and a previous depressive episode. Differentiating between primary and secondary mania is difficult, as people with bipolar disorder are prone to multiple psychiatric and nonpsychiatric comorbidities, in this case, the differential diagnosis included secondary mania, corticoid-induced manic episode and primary bipolar disorder. Read More

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Fecal Short-Chain Fatty Acid Ratios as Related to Gastrointestinal and Depressive Symptoms in Young Adults.

Psychosom Med 2021 Sep;83(7):693-699

From the Department of Molecular Sciences, BioCentrum (Müller, Jayarathna, Moazzami), Swedish University of Agricultural Sciences; and Department of Neurosciences, Psychiatry (Rasmusson, Just, Novicic, Cunningham), Uppsala University Hospital, Uppsala, Sweden.

Objective: Short-chain fatty acids (SCFAs) are produced by the gut microbiota and may reflect health. Gut symptoms are common in individuals with depressive disorders, and recent data indicate relationships between gut microbiota and psychiatric health. We aimed to investigate potential associations between SCFAs and self-reported depressive and gut symptoms in young adults. Read More

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September 2021

National Practice Guidelines for Peer Support Specialists and Supervisors.

Psychiatr Serv 2021 Jul 13:appips202000901. Epub 2021 Jul 13.

National Association of Peer Supporters, Washington, D.C. (Foglesong, Edwards); South Florida Wellness Network, Fort Lauderdale (Knowles); Department of Psychiatric Rehabilitation, School of Health Professions, Rutgers University Piscataway, New Jersey (Cronise); Department of Psychiatry, Yale University, New Haven, Connecticut (Wolf). Nev Jones, Ph.D., and Keris Jän Myrick, M.B.A., M.S., are editors of this column.

In 2017, the National Association of Peer Supporters (N.A.P. Read More

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Erectile and Ejaculatory Dysfunction Associated with Use of Psychotropic Drugs: A Systematic Review.

J Sex Med 2021 08 8;18(8):1354-1363. Epub 2021 Jul 8.

Department of Urology, IRCCS Ca' Granda Ospedale Maggiore Policlinico - University of Milan, Milan, Italy. Electronic address:

Background: Sexual dysfunction may be a side effect of treatment with antipsychotics, antidepressants, and other psychotropic drugs.

Aim: To review the evidence concerning male sexual dysfunctions in patients taking psychotropic drugs to provide specific information to nonpsychiatric physicians for the management of these dysfunctions.

Methods: A systematic search of Medline and Embase databases was performed up to October 15, 2020. Read More

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Medicinal cannabis: knowledge, beliefs, and attitudes of Colombian psychiatrists.

J Cannabis Res 2021 Jul 5;3(1):26. Epub 2021 Jul 5.

Pontificia Universidad Javeriana, Bogotá, Colombia.

Background: The use of cannabinoids in mental health has gained strength in recent years due to emerging scientific evidence and the lifting of prohibitionist laws that prevailed for years in many countries, including Colombia. This study describes the results of a survey of Colombian psychiatrists on some aspects of medicinal cannabis, such as attitudes towards its potential use, perceived knowledge, and beliefs surrounding its regulation and safety.

Methods: We conducted a cross-sectional survey of 145 psychiatrists in 14 territories of Colombia between November 2019 and July 2020. Read More

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Mapping of Transdiagnostic Neuropsychiatric Phenotypes Across Patients in Two General Hospitals.

J Acad Consult Liaison Psychiatry 2021 Jul-Aug;62(4):430-439. Epub 2021 Mar 4.

Center for Quantitative Health, Massachusetts General Hospital, Boston, MA. Electronic address:

Background: Multidimensional transdiagnostic phenotyping systems are increasingly important to neuropsychiatric phenotyping, particularly in translational research settings. The relationship the National Institute of Mental Health's Research Domain Criteria multidimensional approach to psychopathology and nonpsychiatric diagnoses has not been studied at scale but is relevant to those caring for neuropsychiatric illness in medical and surgical settings.

Methods: We applied the CQH Dimensional Phenotyper natural language processing tool to estimate National Institute of Mental Health's Research Domain Criteria domain-associated symptoms of individuals admitted to nonpsychiatric wards at each of 2 large academic general hospitals over an 8-year period. Read More

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The viability of the frequency following response characteristics for use as biomarkers of cognitive therapeutics in schizophrenia.

Schizophr Res 2021 Jun 26. Epub 2021 Jun 26.

VISN 22 Mental Illness Research, Education, & Clinical Center (MIRECC), San Diego VA Healthcare System, San Diego, CA, USA; Department of Psychiatry, University of California San Diego, San Diego, CA, USA.

Deficits in early auditory information processing contribute to cognitive and psychosocial disability; this has prompted development of interventions that target low-level auditory processing, which may alleviate these disabilities. The frequency following response (FFR) is a constellation of event-related potential and frequency characteristics that reflect the processing of acoustic stimuli at the level of the brainstem and ascending portions of the auditory pathway. While FFR is a promising candidate biomarker of response to auditory-based cognitive training interventions, the psychometric properties of FFR in schizophrenia patients have not been studied. Read More

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Event-related potentials to rare visual targets and negative symptom severity in a transdiagnostic psychiatric sample.

Clin Neurophysiol 2021 07 9;132(7):1526-1536. Epub 2021 Apr 9.

Department of Psychology, University of Central Florida, 4111 Pictor Lane, Orlando, FL 32816, USA. Electronic address:

Objectives: Negative psychiatric symptoms are often resistant to treatments, regardless of the disorder in which they appear. One model for a cause of negative symptoms is impairment in higher-order cognition. The current study examined how particular bottom-up and top-down mechanisms of selective attention relate to severity of negative symptoms across a transdiagnostic psychiatric sample. Read More

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Clinical, Neuroimmunologic, and CSF Investigations in First Episode Psychosis.

Neurology 2021 07 12;97(1):e61-e75. Epub 2021 May 12.

From the Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) (M.G., E.M., E.M.-H., M.B., Y.M.-O., G.S., I.P, L.S., A.S., F.G., J.C.-F., E.P., J.D.), Hospital Clínic, and Department of Medicine (M.B., A.S., J.C.-F., E.P.), Universitat de Barcelona; Neurology Department (M.G., E.M.-H., A.S., J.D.), Department of Child and Adolescent Psychiatry and Psychology (M.R.-J., G.S., J.C.-F.), Barcelona Clínic Schizophrenia Unit (BCSU) (M.B., E.P.), and Bipolar and Depressive Disorders Unit (I.P.), Institute of Neuroscience, Hospital Clínic; Centro de Investigación Biomédica en Red (M.G., E.M.-H., L.S., J.D.), Enfermedades Raras (CIBERER); Psychiatry Department (E.G.-S., E.B.-Q., E.D.-L.), Hospital de Mataró Consorci Sanitari del Maresme, Mataró; Centro de Investigación Biomédica en Red (M.B., G.S., I.P., J.C.-F., E.P.), Salud Mental (CIBERSAM); Neurology Department (V.C., N.G., D.M., C.T.-R.), Hospital de Mataró Consorci Sanitari del Maresme; Medical Statistics Core Facility (J.R.), IDIBAPS and Hospital Clínic, Barcelona, Spain; Department of Neurology (J.D.), Perelman School of Medicine, University of Pennsylvania, Philadelphia; and Catalan Institute for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.

Objectives: To report the neuropsychiatric features and frequency of NMDA receptor (NMDAR) and other neuronal immunoglobulin G antibodies in patients with first episode psychosis (FEP) and to assess the performance of reported warning signs and criteria for autoimmune psychosis (AP).

Methods: This was a prospective observational study of patients with FEP assessed for neuropsychiatric symptoms, serum and CSF neuronal antibodies (brain immunohistochemistry, cell-based assays, live neurons), and warning signs and criteria of AP. Previous autoimmune FEP series were reviewed. Read More

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Patterns and Impact of Electronic Health Records-Defined Depression Phenotypes in Spine Surgery.

Neurosurgery 2021 06;89(1):E19-E32

Pacific Northwest University of Health Sciences, Yakima, Washington, USA.

Background: Preoperative depression is a risk factor for poor outcomes after spine surgery.

Objective: To understand effects of depression on spine surgery outcomes and healthcare resource utilization.

Methods: Using IBM's MarketScan Database, we identified 52 480 patients who underwent spinal fusion. Read More

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Healthcare burden and factors of type 2 diabetes mellitus with Schizophrenia.

Eur Arch Psychiatry Clin Neurosci 2021 Apr 15. Epub 2021 Apr 15.

Department of Healthcare Administration and Medical Informatics, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.

This study investigated healthcare utilization and expenditure for patients with type 2 diabetes mellitus and schizophrenia and associated factors. Healthcare utilization (outpatient visits and hospitalization) and expenditure (outpatient, inpatient, and total medical expenditure) between 2002 and 2013 of patients with T2DM with schizophrenia (case group) and without (control group) were examined using the Taiwan National Health Insurance Research Database. (1) The average total numbers of outpatient visits and hospital admissions of the case group were 35. Read More

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Storying the Past and the Future: Agency and Communion Themes Among Individuals With Schizophrenia and Depression.

J Nerv Ment Dis 2021 May;209(5):343-352

Abstract: Research has linked disturbances in narrative identity with schizophrenia and other psychiatric disorders. One such disturbance is diminished agency and communion themes in past life stories. However, projecting oneself into the future is also central to identity and potentially impacts recovery. Read More

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Prevalence of corona-associated anxiety and mental health disorder among dentists during the COVID-19 pandemic.

Neuropsychopharmacol Rep 2021 06 6;41(2):223-229. Epub 2021 Apr 6.

Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Birjand University of Medical Sciences, Birjand, Iran.

Aim: The aim of this study was to investigate the prevalence and severity of corona-associated anxiety and mental health disorder among Iranian dentists during the COVID-19 pandemic.

Methods: A study was conducted using online survey from May 2nd to 14th, 2020. The questionnaire consisted of three sections: demographic information, anxiety (18 questions), and general health (GH) (GHQ-28). Read More

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Obsessive-Compulsive Symptoms as a Manifestation of Homocystinuria.

Case Rep Psychiatry 2021 20;2021:5523453. Epub 2021 Mar 20.

Centro Hospitalar Barreiro Montijo, Barreiro, Portugal.

Homocystinuria is a rare autosomal recessive metabolic disorder due to a defect in the cystathionine -synthase (CBS) that leads to high homocysteine plasma levels. Psychiatric symptoms secondary to homocystinuria have been described in the literature; however, there is a lack of information about obsessive-compulsive symptoms correlated to this disorder. We describe the case of a 39 years old man, diagnosed with homocystinuria in childhood, with no previous psychiatric history that presented obsessive-compulsive disorder (OCD) like symptoms, as a manifestation of homocystinuria. Read More

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Utility of MyHEARTSMAP in Youth Presenting to the Emergency Department with Mental Health Concerns.

J Pediatr 2021 Aug 2;235:124-129. Epub 2021 Apr 2.

Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

Objectives: To evaluate the utility of a digital psychological self-assessment tool, MyHEARTSMAP (scores on 10 sections: home, education and activities, alcohol and drugs, relationships and bullying, thoughts and anxiety, safety, sexual health, mood, abuse, and professional resources), in youth presenting to the pediatric emergency department (ED) with a mental health concern.

Study Design: We conducted a prospective cohort study in 2 tertiary care pediatric EDs from December 2017 to October 2019. Youth 10-17 years old triaged for a mental health concern were screened and enrolled to complete MyHEARTSMAP on a mobile device. Read More

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Psychological distress among medically complex veterans with a recent emergency department visit.

Psychol Serv 2021 Apr 1. Epub 2021 Apr 1.

Geriatric Research, Education, and Clinical Center (GRECC), Durham VA Health Care System.

Medical complexity and psychological distress are associated with frequent emergency department (ED) use. Despite this known association, our understanding is limited about which patients are at risk for persistent psychological distress and what patterns of distress emerge over time. A secondary data analysis was used to examine self-reported psychological distress (defined as ≥14 unhealthy days due to poor mental health in the past month) at 30 and 180 days following enrollment in a randomized control trial of 513 medically complex Veterans after a nonpsychiatric ED visit. Read More

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MAP2 is differentially phosphorylated in schizophrenia, altering its function.

Mol Psychiatry 2021 Feb 1. Epub 2021 Feb 1.

Department of Psychiatry, Translational Neuroscience Program, School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.

Schizophrenia (Sz) is a highly polygenic disorder, with common, rare, and structural variants each contributing only a small fraction of overall disease risk. Thus, there is a need to identify downstream points of convergence that can be targeted with therapeutics. Reduction of microtubule-associated protein 2 (MAP2) immunoreactivity (MAP2-IR) is present in individuals with Sz, despite no change in MAP2 protein levels. Read More

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February 2021

Evaluation of intramuscular olanzapine and ziprasidone in the medically ill.

Ment Health Clin 2021 Jan 8;11(1):6-11. Epub 2021 Jan 8.

Rhona Arenstein Professor of Psychiatry, Virginia Commonwealth University Health System, Department of Psychiatry, Virginia Commonwealth University School of Medicine, Richmond, Virginia.

Introduction: Despite the paucity of studies evaluating short-acting parenteral second-generation antipsychotics in the medically ill, their use in this population has increased. The purpose of this study was to characterize the use of IM olanzapine and ziprasidone in the medically ill at an academic medical center.

Methods: This is a retrospective medical record review of all patients who received IM olanzapine or ziprasidone on nonpsychiatric inpatient units at a large academic medical center from August 1, 2015 to July 31, 2017. Read More

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January 2021

Assessment of Racial Differences in Pharmacotherapy Efficacy for Smoking Cessation: Secondary Analysis of the EAGLES Randomized Clinical Trial.

JAMA Netw Open 2021 01 4;4(1):e2032053. Epub 2021 Jan 4.

Department of Medicine, Bioengineering, and Therapeutic Sciences, University of California, San Francisco.

Importance: Understanding Black vs White differences in pharmacotherapy efficacy and the underlying reasons is critically important to reducing tobacco-related health disparities.

Objective: To compare pharmacotherapy efficacy and examine variables to explain Black vs White differences in smoking abstinence.

Design, Setting, And Participants: This study is a secondary analysis of the Evaluating Adverse Events in a Global Smoking Cessation Study (EAGLES) double-blind, placebo-controlled, randomized clinical trial, which took place at clinical trial centers, academic centers, and outpatient clinics in 29 states in the US. Read More

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January 2021

Relationship of Hair Cortisol with History of Psychosis, Neuropsychological Performance and Functioning in Remitted Later-Life Major Depression.

Neuropsychobiology 2021 13;80(4):313-320. Epub 2021 Jan 13.

Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

Introduction: Major depressive disorder (MDD) is associated with hypothalamic-pituitary-adrenal axis dysfunction that may persist into remission. Preliminary evidence suggests that this dysfunction may be associated with impaired neuropsychological performance in remitted MDD. MDD with psychotic features ("psychotic depression") is associated with greater neuropsychological and functional impairment than nonpsychotic depression, including in remission. Read More

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January 2021

Accuracy of initial psychiatric diagnoses given by nonpsychiatric physicians: A retrospective chart review.

Medicine (Baltimore) 2020 Dec;99(51):e23708

Department of Psychiatry, McGill University, Montreal, Quebec, Canada.

Abstract: Despite the increased morbidity and mortality associated with psychiatric illnesses, there remains a substantial level of inaccuracy of the initial psychiatric diagnoses given by nonpsychiatric physicians. This study examines the accuracy of initial psychiatric diagnoses by non-psychiatric physicians at the McGill University Health Center (MUHC).We conducted a retrospective chart review for all consultations requested from the consultation-liaison psychiatry service at MUHC. Read More

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December 2020

Reliability and validity of the Chinese version of the post-traumatic embitterment disorder self-rating scale (PTED-21) among inpatients in general hospital.

Clin Psychol Psychother 2021 Jul 30;28(4):882-890. Epub 2020 Dec 30.

Department of Psychosomatics and Psychiatry, Zhongda Hospital, Medical School, Southeast University, Nanjing, China.

Embitterment and in some cases also post-traumatic embitterment disorder (PTED) are relevant problem in the general population and even more so in psychiatric patients. PTED screening should be an essential component of routine mental health management, which can be done by the 21-item Post-traumatic Embitterment Disorder Self-Rating Scale (C-PTED-21), which measures the intensity of reactive stimulus bound embitterment. The PTED-21 German version was translated into Chinese, and 200 nonpsychiatric inpatients, reporting major negative life events, were recruited through convenience sampling to evaluate test performance. Read More

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