107 results match your criteria pswe

Liver fibrosis assessment: MR and US elastography.

Abdom Radiol (NY) 2021 Oct 23. Epub 2021 Oct 23.

Division of Abdominal Imaging, Radiology, Mayo Clinic Rochester, 200, First Street SW, Rochester, MN, 55905, USA.

Elastography has emerged as a preferred non-invasive imaging technique for the clinical assessment of liver fibrosis. Elastography methods provide liver stiffness measurement (LSM) as a surrogate quantitative biomarker for fibrosis burden in chronic liver disease (CLD). Elastography can be performed either with ultrasound or MRI. Read More

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October 2021

Reliability of performing ultrasound derived SWE and fat fraction in adult livers.

Clin Imaging 2021 Dec 17;80:424-429. Epub 2021 Sep 17.

Rocky Vista University, Ivins, UT, USA.

Purpose: The aim of the study was to test the reproducibility of performing conventional point shear wave elastography (pSWE), auto-pSWE, and ultrasound derived fat fraction (UDFF) in adult livers.

Methods: The Institutional Review Board approved the study and all participants provided written informed consent. Conventional pSWE (obtaining 10 measurements through 10 acquisitions), auto-pSWE (automatically obtaining 15 measurements by a single acquisition), and UDFF (one measurement obtained by one acquisition) of the liver were prospectively performed in 21 participants (10 men, 11 women, mean age 63y) by senior and junior operators in February-May 2021. Read More

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December 2021

Fluctuating biomarkers in primary sclerosing cholangitis: A longitudinal comparison of alkaline phosphatase, liver stiffness, and ELF.

JHEP Rep 2021 Oct 2;3(5):100328. Epub 2021 Jul 2.

Norwegian PSC Research Centre, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital Rikshospitalet, Oslo, Norway.

Background & Aims: Primary sclerosing cholangitis (PSC) is a progressive liver disease characterised by fluctuating liver biochemistries and highly variable disease progression. The Enhanced Liver Fibrosis (ELF®) test and liver stiffness measurements (LSMs) reflect fibrosis and predict clinical outcomes in PSC; however, longitudinal assessments are missing. We aimed to characterise the systematic change in ELF and LSM over time in a prospective cohort of patients with PSC, along with their longitudinal relationship to alkaline phosphatase (ALP) and bilirubin. Read More

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October 2021

Evaluation of Children and Adolescent with Cystic Fibrosis by Pancreatic Elastography.

Pediatr Int 2021 Aug 13. Epub 2021 Aug 13.

Dicle University School of Medicine, Department of Pulmonology, Diyarbakir, Turkey.

Background: Cystic fibrosis (CF) is an autosomal recessively inherited disease. Clinical findings vary by age of the patient, the organ systems involved, and the severity of the CFTR gene mutation. Pancreatic and liver involvement is prominent and exocrine pancreatic insufficiency is observed in the majority of patients. Read More

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Non-invasive assessment of fibrosis regression and portal hypertension in patients with advanced chronic hepatitis C virus (HCV)-associated liver disease and sustained virologic response (SVR): 3 years follow-up of a prospective longitudinal study.

J Viral Hepat 2021 Nov 1;28(11):1604-1613. Epub 2021 Oct 1.

Medizinische Klinik 1, Universitätsklinikum Frankfurt, Frankfurt am Main, Germany.

Long-term effects on cirrhosis and portal hypertension of direct antiviral agent (DAA)-based eradication of hepatitis C virus (HCV) are still under debate. We analysed dynamics of liver and spleen elastography to assess potential regression of cirrhosis and portal hypertension 3 years post-treatment. Fifty-four patients with HCV-associated cirrhosis and DAA-induced SVR were included. Read More

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November 2021

Diagnostic performance of shear wave elastography and diffusion-weighted magnetic resonance imaging in cervical lymph nodes: a comparative study.

Turk J Med Sci 2021 Aug 2. Epub 2021 Aug 2.

Background/aim: To investigate the potential diagnostic value of point shear wave elastography (pSWE) and the contribution of concurrent diffusion weighted magnetic resonance imaging (DW-MRI) to diagnostic performance in patients with cervical lymphadenopathy.

Materials And Methods: This cross-sectional study included 116 cervical lymph nodes of 94 patients. All lymph nodes were evaluated before the treatment or histopathological sampling. Read More

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Spleen Stiffness for Predicting Varices Needing Treatment: Comparison between Two Different Elastography Techniques (Point vs. 2D-SWE).

Can J Gastroenterol Hepatol 2021 28;2021:6622726. Epub 2021 Mar 28.

Department of Gastroenterology and Hepatology, Victor Babeş University of Medicine and Pharmacy, Timişoara, Romania.

The study aimed to establish the benefits of using spleen stiffness values measured by two elastography techniques as noninvasive markers for predicting varices needing treatment and comparing their performances. A prospective study was performed, including 107 subjects with compensated liver cirrhosis, who underwent upper digestive endoscopy, as well as spleen stiffness measurements by means of two elastography techniques: pSWE (point shear wave elastography using Virtual Touch Quantification-Siemens Acuson S2000) and 2D-SWE (2D-shear wave elastography-LOGIQ E9, General Electric). Reliable spleen stiffness measurements were obtained in 96. Read More

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Diagnostic accuracy of elastography and magnetic resonance imaging in patients with NAFLD: A systematic review and meta-analysis.

J Hepatol 2021 10 13;75(4):770-785. Epub 2021 May 13.

Oxford Centre for Clinical Magnetic Resonance Research, Radcliffe Department of Medicine, University of Oxford, Oxford, UK; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, UK; NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust and the University of Oxford, Oxford, UK. Electronic address:

Background And Aims: Vibration-controlled transient elastography (VCTE), point shear wave elastography (pSWE), 2-dimensional shear wave elastography (2DSWE), magnetic resonance elastography (MRE), and magnetic resonance imaging (MRI) have been proposed as non-invasive tests for patients with non-alcoholic fatty liver disease (NAFLD). This study evaluated their diagnostic accuracy for liver fibrosis and non-alcoholic steatohepatitis (NASH).

Methods: PubMED/MEDLINE, EMBASE and the Cochrane Library were searched for studies examining the diagnostic accuracy of these index tests, against histology as the reference standard, in adult patients with NAFLD. Read More

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October 2021

Measurements of Serum Mac-2-Binding Protein Glycosylation Isomer and Shear Wave Velocity in Health Checkups Are Useful in Screening for Non-Alcoholic Steatohepatitis.

Healthcare (Basel) 2021 Apr 29;9(5). Epub 2021 Apr 29.

Department of Internal Medicine, Wakayama Rosai Hospital, Wakayama 640-8505, Japan.

Liver-related mortality rates in patients with non-alcoholic steatohepatitis (NASH) increase with advancing liver fibrosis stage. The present study aimed to elucidate whether adding non-invasive liver fibrosis tests to a comprehensive health checkup system is useful for NASH screening. Both serum Mac-2-binding protein glycosylation isomer (M2BPGi) and point shear wave elastography (pSWE) using ultrasonography were performed for 483 health checkup subjects who consented to participate in this prospective study. Read More

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Is There a Place for Elastography in the Diagnosis of Hepatocellular Carcinoma?

J Clin Med 2021 Apr 15;10(8). Epub 2021 Apr 15.

Department of Gastroenterology and Hepatology, "Victor Babeș" University of Medicine and Pharmacy, 300041 Timișoara, Romania.

Background And Aims: Elastography can provide information regarding tissue stiffness (TS). This study aimed to analyze the elastographic features of hepatocellular carcinoma (HCC) and the factors that influence intratumoral elastographic variability in patients with liver cirrhosis.

Methods: This prospective study included 115 patients with liver cirrhosis and hepatocellular carcinoma evaluated between June 2016-November 2019. Read More

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Point Shear Wave Elastography for Assessing Liver Stiffness in Chronic Liver Diseases of Different Etiologies Compared to Biopsy.

Isr Med Assoc J 2021 Apr;23(4):223-228

Department of Radiology, Rambam Health Care Campus, Haifa, Israel.

Background: Point shear-wave elastography (pSWE) is a new method to assess the degree of liver fibrosis. It has been shown to be effective in detecting stiffness in viral hepatitis.

Objectives: To determine the feasibility of pSWE for assessing liver stiffness and fibrosis in liver diseases of different etiologies. Read More

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Determining the effects of excess weight on renal cortical stiffness in children and adolescents with point Shear Wave Elastography.

Med Ultrason 2021 Aug 14;23(3):271-276. Epub 2021 Mar 14.

Metabolism and nutrition of pediatrics, Erciyes university, Kayseri, Turkey.

Aim: To determine the early effects of excess weight on renal cortical stiffness in children and adolescents using point shear wave elastography (pSWE).

Materials And Methods: One hundred and forty-six overweight and obese children (43.2% male; mean age, 12. Read More

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Point shear wave elastography of the liver in healthy adult cats.

Am J Vet Res 2021 Apr;82(4):286-291

Objective: To evaluate stiffness of the liver parenchyma in healthy adult cats by means of point shear wave elastography (PSWE).

Animals: 18 client-owned adult (1- to 6-year-old) healthy cats.

Procedures: Echogenicity and echotexture of the liver parenchyma were assessed by means of conventional B-mode ultrasonography. Read More

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Cystic fibrosis and noninvasive liver fibrosis assessment methods in children.

Pediatr Res 2021 Mar 17. Epub 2021 Mar 17.

Pediatric Hepatology and Gastroenterology Unit, Bordeaux University Hospital, Pellegrin-Enfants Hospital, Bordeaux, France.

Background: Noninvasive assessments of liver fibrosis are currently used to evaluate cystic fibrosis (CF)-related liver disease. However, there is scarce data regarding their repeatability and reproducibility, especially in children with CF. The present study aimed to evaluate the repeatability and reproducibility of transient elastography (TE) (FibroScan®) and point shear-wave elastography using virtual touch quantification (pSWE VTQ) in children with CF. Read More

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Comparison of Elastography Point Quantification with Transient Elastography in Patients with Chronic Viral Hepatitis and Nonalcoholic Fatty Liver Disease: A Pilot Study.

J Clin Exp Hepatol 2021 Jan-Feb;11(1):21-29. Epub 2020 Jul 2.

Departments of Radiodiagnosis and Imaging, Chandigarh, 160012, India.

Aims: The objective of this study was to compare diagnostic accuracy of elastography point quantification (ElastPQ) with transient elastography (TE) and liver histology for measuring liver stiffness in patients with chronic viral hepatitis (CVH) and nonalcoholic fatty liver disease (NAFLD).

Methods: Thirty-two patients with chronic liver disease (CVH and NAFLD) were evaluated by ElastPQ and TE within 7 days of liver biopsy. Within the CVH group, subgroup analysis was carried out in patients with end-stage renal disease (ESRD) and without ESRD. Read More

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Evaluation of Schistosomiasis Mansoni Morbidity by Hepatic and Splenic Elastography.

Ultrasound Med Biol 2021 05 20;47(5):1235-1243. Epub 2021 Feb 20.

Postgraduate Program in Tropical Medicine, Center of Medical Sciences, Universidade Federal de Pernambuco (UFPE), Recife, Brazil; Gastroenterology Service, Hospital das Clínicas, UFPE, Recife, Brazil. Electronic address:

In patients with Mansoni schistosomiasis, it is fundamental to evaluate the disease morbidity, which is reflected by the severity of periportal fibrosis (PPF) and parameters of portal hypertension, as analyzed by ultrasonography (US). This study aimed to evaluate the morbidity of schistosomiasis by hepatic and splenic point shear-wave elastography (pSWE) and relate this to US parameters. The PPF pattern, the diameter of the portal and splenic veins and the size of the spleen were evaluated by US. Read More

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Spleen elastography in patients with Systemic sclerosis.

Rheumatol Int 2021 Mar 25;41(3):633-641. Epub 2021 Jan 25.

Medical University - Plovdiv, Plovdiv, Bulgaria.

Systemic sclerosis (SSc) is an autoimmune inflammatory connective tissue disease. It is characterized by varying degrees of fibrosis of the skin and internal organs. Tissue fibrosis is the final phase of a complex biological process of immune activation and vascular damage. Read More

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Shear wave elastography and transient elastography in HCV patients after direct-acting antivirals.

Radiol Med 2021 Jun 25;126(6):894-899. Epub 2021 Jan 25.

Departement of Radiological Sciences, A.O.U Ospedali Riuniti di Ancona, Via Conca 71, 60126, Torrette-Ancona, Italy.

Purpose: To compare the ultrasound (US) and pulse shear wave elastography (pSWE, Elast PQ) methods with transient elastography (TE), clinical scores and laboratory tests, during the follow-up of HCV patients receiving direct-acting antiviral drugs (DAA).

Methods: Our prospective study from June 2016 to December 2017 included 22 consecutively enrolled HCV-positive patients (59.7 ± 12. Read More

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Point Shear-Wave Elastography Using Acoustic Radiation Force Impulse Imaging for the Prediction of Liver-Related Events in Patients With Chronic Viral Hepatitis.

Hepatol Commun 2021 01 12;5(1):112-121. Epub 2020 Nov 12.

Department of Internal Medicine 1 University Hospital Frankfurt Goethe University Frankfurt am Main Germany.

Chronic viral hepatitis is associated with substantial morbidity and mortality worldwide. The aim of our study was to assess the ability of point shear-wave elastography (pSWE) using acoustic radiation force impulse imaging for the prediction of the following liver-related events (LREs): new diagnosis of HCC, liver transplantation, or liver-related death (hepatic decompensation was not included as an LRE). pSWE was performed at study inclusion and compared with liver histology, transient elastography (TE), and serologic biomarkers (aspartate aminotransferase to platelet ratio index, Fibrosis-4, FibroTest). Read More

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January 2021

Analysis of Point Shear Wave Elastography and Biochemical Markers for the Detection of Liver Fibrosis.

Medicina (Kaunas) 2021 Jan 6;57(1). Epub 2021 Jan 6.

Department of Radiodiagnostics and Invasive Radiology, School of Medicine in Katowice, Medical University of Silesia, 40-752 Katowice, Poland.

This work focuses on the possibility of using the point shear wave elastography (pSWE) method for detecting biochemical markers in diffuse liver diseases. Additionally, this study addresses the issue of the influence of ultrasound factors on the pSWE quality indicators of the obtained measurements. A pSWE examination was performed on 139 patients (69 female and 70 male) diagnosed with diffuse liver disease. Read More

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January 2021

Liver Elastography in Healthy Children Using Three Different Systems - How Many Measurements Are Necessary?

Ultraschall Med 2020 Dec 21. Epub 2020 Dec 21.

Medicine, Haraldsplass Diakonale Sykehus AS, Bergen, Norway.

Purpose:  Liver elastography is increasingly being applied in screening for and follow-up of pediatric liver disease, and has been shown to correlate well with fibrosis staging through liver biopsy. Because time is of the essence when examining children, we wanted to evaluate if a reliable result can be achieved with fewer acquisitions.

Materials And Methods:  243 healthy children aged 4-17 years were examined after three hours of fasting. Read More

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December 2020

Comparison of 2-D Shear Wave Elastography and Point Shear Wave Elastography for Assessing Liver Fibrosis.

Ultrasound Med Biol 2021 03 17;47(3):408-427. Epub 2020 Dec 17.

Organ Transplant Center, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China; Guangdong Provincial Key Laboratory of Organ Donation and Transplant Immunology, First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China; Guangdong Provincial International Cooperation Base of Science and Technology (Organ Transplantation), First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China. Electronic address:

Progressive liver fibrosis may result in cirrhosis, portal hypertension and increased risk of hepatocellular carcinoma. We performed a meta-analysis to compare liver fibrosis staging in chronic liver disease patients using 2-D shear wave elastography (2-D SWE) and point shear wave elastography (pSWE). The PubMed, Web of Science and Cochrane Library databases were searched until May 31, 2020 for studies evaluating the diagnostic performance of 2-D SWE and pSWE in assessing liver fibrosis. Read More

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Point Shear Wave Elastography and the Effect of Physical Exercise, Alcohol Consumption, and Respiration in Healthy Adults.

Ultrasound Int Open 2020 Dec 8;6(3):E54-E61. Epub 2020 Dec 8.

Department of Clinical Science, University of Bergen Faculty of Medicine and Dentistry, Bergen, Norway.

Ultrasound elastography is a noninvasive method for liver stiffness measurement (LSM) with the aim of reflecting approximate liver fibrosis load. Despite minimal evidence, current guidelines recommend 10 min of rest and breath hold prior to measurements and offer no advice concerning recent alcohol consumption, leading to challenges in clinical practice. We aimed to investigate how LSM in healthy adults is influenced by physical exercise, recent alcohol consumption, and respiration. Read More

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December 2020

Spleen Stiffness Predicts Survival after Transjugular Intrahepatic Portosystemic Shunt in Cirrhotic Patients.

Biomed Res Int 2020 13;2020:3860390. Epub 2020 Nov 13.

Department of Gastroenterology, Affiliated Drum Tower Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.

Objectives: Transjugular intrahepatic portosystemic shunt (TIPS) is an effective intervention for portal hypertensive complications. Little is known about the ability of spleen stiffness (SS) for predicting the survival of cirrhotic patients undergoing TIPS. This study is to evaluate the influence of SS detected by point shear wave elastography (pSWE) in predicting survival after TIPS. Read More

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Diagnostic value of conventional ultrasound and shear wave elastography in detecting transjugular intrahepatic portosystemic shunt dysfunction.

Acta Radiol 2021 Dec 28;62(12):1575-1582. Epub 2020 Nov 28.

Department of Ultrasound, Jinling Hospital, Nanjing Medical University, Nanjing, PR China.

Background: Transjugular intrahepatic portosystemic shunt (TIPS) dysfunction can cause recurrent portal hypertension (PH)-related complications such as ascites and gastroesophageal variceal bleeding. Portography is invasive and costly limits its use as a screening modality.

Purpose: To assess the clinical value of conventional ultrasound in combination with point shear wave elastography (pSWE) to predict TIPS dysfunction. Read More

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December 2021

The effect of maternal vitamin D levels on placental shear wave elastography findings in the first trimester.

J Obstet Gynaecol 2021 Aug 16;41(6):860-863. Epub 2020 Oct 16.

Division of Perinatology, Department of Obstetrics and Gynecology, School of Medicine, Manisa Celal Bayar University, Manisa, Turkey.

The aim of this study was to investigate the effect of maternal serum Vitamin D levels on the elasticity of placenta. Seventy-four spontaneously conceived singleton pregnancies in their first trimester were enrolled into this study. Fifty-one of them had Vitamin D deficiency (<20 ng/mL), while 23 pregnancies had Vitamin D levels ≥20 ng/mL. Read More

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Hepatocellular Carcinoma and Non-Alcoholic Fatty Liver Disease: A Step Forward for Better Evaluation Using Ultrasound Elastography.

Cancers (Basel) 2020 Sep 28;12(10). Epub 2020 Sep 28.

Community Medicine Department, Iuliu Hatieganu University of Medicine and Pharmacy, 400001 Cluj-Napoca, Romania.

The increasing prevalence of non-alcoholic fatty liver disease (NAFLD) in the general population prompts for a quick response from physicians. As NAFLD can progress to liver fibrosis, cirrhosis, and even hepatocellular carcinoma (HCC), new non-invasive, rapid, cost-effective diagnostic methods are needed. In this review, we explore the diagnostic performance of ultrasound elastography for non-invasive assessment of NAFLD and NAFLD-related HCC. Read More

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September 2020

Hepatitis C Clearance by Direct-Acting Antivirals Impacts Glucose and Lipid Homeostasis.

J Clin Med 2020 Aug 21;9(9). Epub 2020 Aug 21.

Department of Internal Medicine, University Hospital Frankfurt, 60596 Frankfurt, Germany.

Background: Chronic hepatitis C virus (HCV) infections are causally linked with metabolic comorbidities such as insulin resistance, hepatic steatosis, and dyslipidemia. However, the clinical impact of HCV eradication achieved by direct-acting antivirals (DAAs) on glucose and lipid homeostasis is still controversial. The study aimed to prospectively investigate whether antiviral therapy of HCV with DAAs alters glucose and lipid parameters. Read More

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Liver stiffness value obtained by point shear-wave elastography is significantly related with atrial septal defect size.

Diagn Interv Radiol 2020 Jul;26(4):284-291

Department of Cardiology, University of Health Sciences Adana Health Practice and Research Center, Adana, Turkey.

PURPOSE The increase in volume and pressure in the right atrium (RA) and right ventricle (RV) has been shown to increase the liver stiffness (LS). In the literature, there is no information about the changes in LS value in patients with atrial septal defect (ASD). The aim of our study was to investigate the change of LS values obtained by point shear-wave elastography (pSWE) in patients with ASD and the clinical utility of pSWE for this disease. Read More

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Virtual Touch Quantification using Acoustic Radiation Force Impulse Imaging Technology versus Transient Elastography for the Noninvasive Assessment of Liver Fibrosis in Patients with Chronic Hepatitis B or C using Liver Biopsy as the Gold Standard.

J Gastrointestin Liver Dis 2020 Jun 3;29(2):181-190. Epub 2020 Jun 3.

Department of Gastroenterology and Hepatology, Victor Babeș University of Medicine and Pharmacy, Timișoara, Romania.

Aims: Our aim was to assess the diagnostic performance of transient elastography (TE) and Virtual Touch Quantification (VTQ), a point Shear Wave Elastography (pSWE) technique, using Acoustic Radiation Force Impulse (ARFI) technology, for liver fibrosis assessment, as compared to percutaneous liver biopsy (LB), in patients with chronic hepatitis B or C.

Methods: We analyzed 157 patients (80 with chronic hepatitis B and 77 with chronic hepatitis C) with reliable liver stiffness (LS) measurements, in whom we compared TE and VTQ to the LB performed during the same session (evaluated according to the Metavir scoring system: F0-F4). LS was assessed by TE (FibroScan, EchoSens, Paris, France) and VTQ using the Siemens Acuson S2000TM ultrasound system (Siemens AG, Erlangen, Germany). Read More

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